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Select item 88944501.

Structural basis of leukotriene B4 receptor 1 activation

Na Wang, Xinheng He, Jing Zhao, Hualiang Jiang, Xi Cheng, Yu Xia, H. Eric Xu, Yuanzheng He

Nat Commun. 2022; 13: 1156. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28820-9

PMCID:: PMC8894450

Abstract Article PDF–2.5M

Select item 81379292.

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

Nairie Michaelian, Anastasiia Sadybekov, Élie Besserer-Offroy, Gye Won Han, Harini Krishnamurthy, Beata A. Zamlynny, Xavier Fradera, Phieng Siliphaivanh, Jeremy Presland, Kerrie B. Spencer, Stephen M. Soisson, Petr Popov, Philippe Sarret, Vsevolod Katritch, Vadim Cherezov

Nat Commun. 2021; 12: 2971. Published online 2021 May 20. doi: 10.1038/s41467-021-23149-1

PMCID:: PMC8137929

Abstract Article PDF–2.3M

Select item 35298623.

Novel Computational Methodologies for Structural Modeling of Spacious Ligand Binding Sites of G-Protein-Coupled Receptors: Development and Application to Human Leukotriene B4 Receptor

Yoko Ishino, Takanori Harada

ScientificWorldJournal. 2012; 2012: 691579. Published online 2012 Dec 10. doi: 10.1100/2012/691579

PMCID:: PMC3529862

Abstract Article PDF–1.3M

Select item 32589294.

G Protein Activation by the Leukotriene B₄ Receptor Dimer: EVIDENCE FOR AN ABSENCE OF TRANS-ACTIVATION

Marjorie Damian, Sophie Mary, Aimée Martin, Jean-Philippe Pin, Jean-Louis Banères

J Biol Chem. 2008 Jul 25; 283(30): 21084–21092. doi: 10.1074/jbc.M710419200

PMCID:: PMC3258929

Abstract Article PDF–382K

Select item 27625855.

Engineering a G protein-coupled receptor for structural studies: Stabilization of the BLT1 receptor ground state

Aimée Martin, Marjorie Damian, Michel Laguerre, Joseph Parello, Bernard Pucci, Laurence Serre, Sophie Mary, Jacky Marie, Jean-Louis Banères

Protein Sci. 2009 Apr; 18(4): 727–734. Published online 2009 Jan 6. doi: 10.1002/pro.55

PMCID:: PMC2762585

Abstract Article PDF–256K

Select item 47471796.

The proinflammatory LTB₄/BLT1 signal axis confers resistance to TGF-β1-induced growth inhibition by targeting Smad3 linker region

Woo-Kwang Jeon, Jiyeon Choi, Seong Ji Park, Eun Ji Jo, Young K. Lee, Seunghwan Lim, Jae-Hong Kim, John J. Letterio, Fang Liu, Seong-Jin Kim, Byung-Chul Kim

Oncotarget. 2015 Dec 8; 6(39): 41650–41666. Published online 2015 Oct 19. doi: 10.18632/oncotarget.6146

PMCID:: PMC4747179

Abstract Article PDF–4.0M

Select item 36079867.

Leukotriene B₄ receptor locus gene characterisation and association studies in asthma

Asif S Tulah, Bianca Beghé, Sheila J Barton, John W Holloway, Ian Sayers

BMC Med Genet. 2012; 13: 110. Published online 2012 Nov 20. doi: 10.1186/1471-2350-13-110

PMCID:: PMC3607986

Abstract Article PDF–701K

Select item 16988958.

Asymmetric conformational changes in a GPCR dimer controlled by G-proteins

Marjorie Damian, Aimée Martin, Danielle Mesnier, Jean-Philippe Pin, Jean-Louis Banères

EMBO J. 2006 Dec 13; 25(24): 5693–5702. Published online 2006 Nov 30. doi: 10.1038/sj.emboj.7601449

PMCID:: PMC1698895

Abstract Article PDF–300K

Select item 14407679.

Differential induction of BLT receptor expression on human endothelial cells by lipopolysacharide, cytokines, and leukotriene B₄

Hong Qiu, Anne-Sofie Johansson, Mattias Sjöström, Min Wan, Oliver Schröder, Jan Palmblad, Jesper Z. Haeggström

Proc Natl Acad Sci U S A. 2006 May 2; 103(18): 6913–6918. Published online 2006 Apr 19. doi: 10.1073/pnas.0602208103

PMCID:: PMC1440767

Abstract Article PDF–677K

Select item 129766310.

Leukotriene B₄ signaling through NF-κB-dependent BLT₁ receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia

Magnus Bäck, De-xiu Bu, Robert Bränström, Yuri Sheikine, Zhong-Qun Yan, Göran K. Hansson

Proc Natl Acad Sci U S A. 2005 Nov 29; 102(48): 17501–17506. Published online 2005 Nov 17. doi: 10.1073/pnas.0505845102

PMCID:: PMC1297663

Abstract Article PDF–467K

Select item 121974611.

Signalling through the leukotriene B4 receptor involves both alphai and alpha16, but not alphaq or alpha11 G-protein subunits.

R Gaudreau, C Le Gouill, S Métaoui, S Lemire, J Stankovà, M Rola-Pleszczynski

Biochem J. 1998 Oct 1; 335(Pt 1): 15–18. doi: 10.1042/bj3350015

PMCID:: PMC1219746

Summary PDF–244K

Select item 520363712.

SNAP23-Dependent Surface Translocation of Leukotriene B₄ (LTB₄) Receptor 1 Is Essential for NOX2-Mediated Exocytotic Degranulation in Human Mast Cells Induced by Trichomonas vaginalis-Secreted LTB₄

Arim Min, Young Ah Lee, Kyeong Ah Kim, Jamel El-Benna, Myeong Heon Shin

Infect Immun. 2017 Jan; 85(1): e00526-16. Prepublished online 2016 Oct 24. Published online 2016 Dec 29. doi: 10.1128/IAI.00526-16

PMCID:: PMC5203637

Abstract Article PDF–2.6M

Select item 326768613.

The role of ALOX5AP, LTA4H and LTB4R polymorphisms in determining baseline lung function and COPD susceptibility in UK smokers

Asif S Tulah, Stuart G Parker, Miriam F Moffatt, Andrew J Wardlaw, Martin J Connolly, Ian Sayers

BMC Med Genet. 2011; 12: 173. Published online 2011 Dec 29. doi: 10.1186/1471-2350-12-173

PMCID:: PMC3267686

Abstract Article PDF–278K

Select item 219322414.

Cell-Specific Transcriptional Regulation of Human Leukotriene B₄ Receptor Gene

Kazuhiko Kato, Takehiko Yokomizo, Takashi Izumi, Takao Shimizu

J Exp Med. 2000 Aug 7; 192(3): 413–420. doi: 10.1084/jem.192.3.413

PMCID:: PMC2193224

Abstract Article PDF–198K

Select item 219321715.

A Second Leukotriene B₄ Receptor, Blt2: A New Therapeutic Target in Inflammation and Immunological Disorders

Takehiko Yokomizo, Kazuhiko Kato, Kan Terawaki, Takashi Izumi, Takao Shimizu

J Exp Med. 2000 Aug 7; 192(3): 421–432. doi: 10.1084/jem.192.3.421

PMCID:: PMC2193217

Abstract Article PDF–220K

Select item 185075316.

5-Lipoxygenase and Leukotriene B₄ Receptor Are Expressed in Human Pancreatic Cancers But Not in Pancreatic Ducts in Normal Tissue

René Hennig, Xian-Zhong Ding, Wei-Gang Tong, Matthias B. Schneider, Jens Standop, Helmut Friess, Markus W. Büchler, Parviz M. Pour, Thomas E. Adrian

Am J Pathol. 2002 Aug; 161(2): 421–428. doi: 10.1016/S0002-9440(10)64198-3

PMCID:: PMC1850753

Abstract Article PDF–605K

Select item 833584417.

SPM Receptor Expression and Localization in Irradiated Salivary Glands

Harim Tavares dos Santos, Kihoon Nam, Jason P. Hunt, Luke O. Buchmann, Marcus M. Monroe, Olga J. Baker

J Histochem Cytochem. 2021 Aug; 69(8): 523–534. Published online 2021 Aug 2. doi: 10.1369/00221554211031678

PMCID:: PMC8335844

Abstract Article PDF–2.9M

Select item 291127518.

Leukotriene B₄ BLT Receptor Signaling Regulates the Level and Stability of Cyclooxygenase-2 (COX-2) mRNA through Restricted Activation of Ras/Raf/ERK/p42 AUF1 Pathway

Beibei Zhai, Huiqing Yang, Arturo Mancini, QingWen He, John Antoniou, John A. Di Battista

J Biol Chem. 2010 Jul 30; 285(31): 23568–23580. Published online 2010 May 19. doi: 10.1074/jbc.M110.107623

PMCID:: PMC2911275

Abstract Article PDF–2.7M

Select item 411454719.

Genome-wide association analyses of child genotype effects and parent-of-origin effects in specific language impairment

R Nudel, N H Simpson, G Baird, A O’Hare, G Conti-Ramsden, P F Bolton, E R Hennessy, S M Ring, G Davey Smith, C Francks, S Paracchini, A P Monaco, S E Fisher, D F Newbury

Genes Brain Behav. 2014 Apr; 13(4): 418–429. Published online 2014 Mar 24. doi: 10.1111/gbb.12127

PMCID:: PMC4114547

Abstract Article PDF–1002K

Select item 266429920.

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women

Rachel T. Palmieri, Melanie A. Wilson, Edwin S. Iversen, Merlise A. Clyde, Brian Calingaert, Patricia G. Moorman, Charles Poole, A. Rebecca Anderson, Stephanie Anderson, Hoda Anton-Culver, Australian Cancer Study (Ovarian Cancer Group), Australian Ovarian Cancer Study Group, Jonathan Beesley, Estrid Hogdall, Wendy Brewster, Michael E. Carney, Xiaoqing Chen, Georgia Chenevix-Trench, Jenny Chang-Claude, Julie M. Cunningham, Richard A. DiCioccio, Jennifer A. Doherty, Douglas F. Easton, Christopher K. Edlund, Simon A. Gayther, Aleksandra Gentry-Maharaj, Ellen L. Goode, Marc T. Goodman, Susanne Kruger Kjaer, Claus K Hogdall, Michael P. Hopkins, Eric L. Jenison, Jan Blaakaer, Galina Lurie, Valerie McGuire, Usha Menon, Kirsten B. Moysich, Roberta B. Ness, Celeste Leigh Pearce, Paul D.P. Pharoah, Malcolm C. Pike, Susan J. Ramus, Mary Anne Rossing, Honglin Song, Keith Y. Terada, David Van Den Berg, Robert A. Vierkant, Shan Wang-Gohrke, Penelope M. Webb, Alice S. Whittemore, Anna H. Wu, Argyrios Ziogas, Andrew Berchuck, Joellen M. Schildkraut

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Dec; 17(12): 3567–3572. doi: 10.1158/1055-9965.EPI-08-0548

PMCID:: PMC2664299

Abstract Article PDF–345K

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