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Select item 98626131.

The Elusive Coreceptors for the SARS-CoV-2 Spike Protein

Reed L. Berkowitz, David A. Ostrov

Viruses. 2023 Jan; 15(1): 67. Published online 2022 Dec 25. doi: 10.3390/v15010067

PMCID:: PMC9862613

Abstract Article PDF–2.1M

Select item 97538912.

Multi-omics identify falling LRRC15 as a COVID-19 severity marker and persistent pro-thrombotic signals in convalescence

Jack S. Gisby, Norzawani B. Buang, Artemis Papadaki, Candice L. Clarke, Talat H. Malik, Nicholas Medjeral-Thomas, Damiola Pinheiro, Paige M. Mortimer, Shanice Lewis, Eleanor Sandhu, Stephen P. McAdoo, Maria F. Prendecki, Michelle Willicombe, Matthew C. Pickering, Marina Botto, David C. Thomas, James E. Peters

Nat Commun. 2022; 13: 7775. Published online 2022 Dec 15. doi: 10.1038/s41467-022-35454-4

PMCID:: PMC9753891

Abstract Article PDF–8.1M

Select item 86004163.

Cancer-associated fibroblast-derived LRRC15 promotes the migration and invasion of triple-negative breast cancer cells via Wnt/β-catenin signalling pathway regulation

Yang Yang, Haiying Wu, Shaoxia Fan, Yanqing Bi, Min Hao, Jian Shang

Mol Med Rep. 2022 Jan; 25(1): 2. Published online 2021 Nov 2. doi: 10.3892/mmr.2021.12518

PMCID:: PMC8600416

Abstract Article PDF–6.4M

Select item 81846924.

Integrated microenvironment‐associated genomic profiles identify LRRC15 mediating recurrent glioblastoma‐associated macrophages infiltration

Haichao Tang, Wensi Liu, Zhaoxu Xu, Jianhang Zhao, Weitao Wang, Zhaojin Yu, Minjie Wei

J Cell Mol Med. 2021 Jun; 25(12): 5534–5546. Published online 2021 May 7. doi: 10.1111/jcmm.16563

PMCID:: PMC8184692

Abstract Article PDF–2.3M

Select item 100865575.

RUNX1 Ameliorates Rheumatoid Arthritis Progression through Epigenetic Inhibition of LRRC15

Hao Ding, Xiaoliang Mei, Lintao Li, Peng Fang, Ting Guo, Jianning Zhao

Mol Cells. 2023 Apr 30; 46(4): 231–244. Published online 2023 Jan 10. doi: 10.14348/molcells.2023.2136

PMCID:: PMC10086557

Abstract Article PDF–41M

Select item 98975556.

LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein

Jarrod Shilts, Thomas W. M. Crozier, Ana Teixeira-Silva, Ildar Gabaev, Pehuén Pereyra Gerber, Edward J. D. Greenwood, Samuel James Watson, Brian M. Ortmann, Christian M. Gawden-Bone, Tekle Pauzaite, Markus Hoffmann, James A. Nathan, Stefan Pöhlmann, Nicholas J. Matheson, Paul J. Lehner, Gavin J. Wright

PLoS Biol. 2023 Feb; 21(2): e3001959. Published online 2023 Feb 3. doi: 10.1371/journal.pbio.3001959

PMCID:: PMC9897555

Abstract Article PDF–2.7M

Select item 85485477.

Transcriptomic and epigenomic analyses uncovered Lrrc15 as a contributing factor to cartilage damage in osteoarthritis

Purva Singh, Mengying Wang, Piali Mukherjee, Samantha G. Lessard, Tania Pannellini, Camila B. Carballo, Scott A. Rodeo, Mary B. Goldring, Miguel Otero

Sci Rep. 2021; 11: 21107. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00269-8

PMCID:: PMC8548547

Abstract Article PDF–5.2M

Select item 23951238.

Tumor Antigen LRRC15 Impedes Adenoviral Infection: Implications for Virus-Based Cancer Therapy

Jim O'Prey, Simon Wilkinson, Kevin M. Ryan

J Virol. 2008 Jun; 82(12): 5933–5939. Published online 2008 Apr 2. doi: 10.1128/JVI.02273-07

PMCID:: PMC2395123

Abstract Article PDF–472K

Select item 1964529.

Identification of a DNA-binding site and transcriptional target for the EWS–WT1(+KTS) oncoprotein

Paul A. Reynolds, Gromoslaw A. Smolen, Rachel E. Palmer, Dennis Sgroi, Vijay Yajnik, William L. Gerald, Daniel A. Haber

Genes Dev. 2003 Sep 1; 17(17): 2094–2107. doi: 10.1101/gad.1110703

PMCID:: PMC196452

Abstract Article PDF–831K

Select item 991074410.

Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs

Lipin Loo, Matthew A. Waller, Cesar L. Moreno, Alexander J. Cole, Alberto Ospina Stella, Oltin-Tiberiu Pop, Ann-Kristin Jochum, Omar Hasan Ali, Christopher E. Denes, Zina Hamoudi, Felicity Chung, Anupriya Aggarwal, Jason K. K. Low, Karishma Patel, Rezwan Siddiquee, Taeyoung Kang, Suresh Mathivanan, Joel P. Mackay, Wolfram Jochum, Lukas Flatz, Daniel Hesselson, Stuart Turville, G. Gregory Neely

PLoS Biol. 2023 Feb; 21(2): e3001967. Published online 2023 Feb 9. doi: 10.1371/journal.pbio.3001967

PMCID:: PMC9910744

Abstract Article PDF–3.1M

Select item 959556311.

LRRC15 inhibits SARS-CoV-2 cellular entry in trans

Jaewon Song, Ryan D. Chow, Mario A. Peña-Hernández, Li Zhang, Skylar A. Loeb, Eui-Young So, Olin D. Liang, Ping Ren, Sidi Chen, Craig B. Wilen, Sanghyun Lee

PLoS Biol. 2022 Oct; 20(10): e3001805. Published online 2022 Oct 13. doi: 10.1371/journal.pbio.3001805

PMCID:: PMC9595563

Abstract Article PDF–3.9M

Select item 1117915812.

Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis

Shuji Gong, Kun Xiang, Le Chen, Huanwei Zhuang, Yaning Song, Jinlan Chen

IET Syst Biol. 2024 Jun; 18(3): 77–91. Published online 2024 Apr 2. doi: 10.1049/syb2.12091

PMCID:: PMC11179158

Abstract Article PDF–3.4M

Select item 648477213.

S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia

Maurizio Gianni, Mineko Terao, Mami Kurosaki, Gabriela Paroni, Laura Brunelli, Roberta Pastorelli, Adriana Zanetti, Monica Lupi, Andrea Acquavita, Marco Bolis, Maddalena Fratelli, Cecile Rochette-Egly, Enrico Garattini

Oncogene. 2019; 38(14): 2482–2500. Published online 2018 Dec 7. doi: 10.1038/s41388-018-0599-z

Correction in:: Oncogene. 2023; 42(3): 254–258.

PMCID:: PMC6484772

Abstract Article PDF–7.7M

Select item 602600514.

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma

Reinaldo Franqui-Machin, Mu Hao, Hua Bai, Zhimin Gu, Xin Zhan, Hasem Habelhah, Yogesh Jethava, Lugui Qiu, Ivana Frech, Guido Tricot, Fenghuang Zhan

J Clin Invest. 2018 Jul 2; 128(7): 2877–2893. Published online 2018 Jun 4. doi: 10.1172/JCI98765

PMCID:: PMC6026005

Abstract Article PDF–13M

Select item 649756915.

Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy

Changlong Liu, Carolyn E. Banister, Phillip J. Buckhaults

Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Res. 2019 May 1; 79(9): 2392–2403. Published online 2019 Mar 12. doi: 10.1158/0008-5472.CAN-18-3024

PMCID:: PMC6497569

Abstract Article PDF–2.2M

Select item 289717316.

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery

Brian D. Freibaum, Raghu Chitta, Anthony A. High, J. Paul Taylor

J Proteome Res. Author manuscript; available in PMC 2011 Feb 5.

Published in final edited form as: J Proteome Res. 2010 Feb 5; 9(2): 1104–1120. doi: 10.1021/pr901076y

PMCID:: PMC2897173

Abstract Article PDF–2.1M

Select item 910272617.

VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway

Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan

J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5

PMCID:: PMC9102726

Abstract Article PDF–15M

Select item 422778618.

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling

Rajat Roy, Danielle Durie, Hui Li, Bing-Qian Liu, John Mark Skehel, Francesco Mauri, Lucia Veronica Cuorvo, Mattia Barbareschi, Lin Guo, Martin Holcik, Michael J. Seckl, Olivier E. Pardo

Nucleic Acids Res. 2014 Nov 10; 42(20): 12483–12497. Published online 2014 Oct 16. doi: 10.1093/nar/gku953

Correction in:: Nucleic Acids Res. 2024 Jul 22; 52(13): 8034.

PMCID:: PMC4227786

Abstract Article PDF–688K

Select item 449890319.

Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme

Célia Jeronimo, Diane Forget, Annie Bouchard, Qintong Li, Gordon Chua, Christian Poitras, Cynthia Thérien, Dominique Bergeron, Sylvie Bourassa, Jack Greenblatt, Benoit Chabot, Guy G. Poirier, Timothy R. Hughes, Mathieu Blanchette, David H. Price, Benoit Coulombe

Mol Cell. Author manuscript; available in PMC 2015 Jul 10.

Published in final edited form as: Mol Cell. 2007 Jul 20; 27(2): 262–274. doi: 10.1016/j.molcel.2007.06.027

PMCID:: PMC4498903

Abstract Article PDF–1.5M

Select item 509804220.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells

Giorgio Oliviero, Gerard L. Brien, Ariane Waston, Gundula Streubel, Emilia Jerman, Darrell Andrews, Benjamin Doyle, Nayla Munawar, Kieran Wynne, John Crean, Adrian P. Bracken, Gerard Cagney

Mol Cell Proteomics. 2016 Nov; 15(11): 3450–3460. Published online 2016 Sep 15. doi: 10.1074/mcp.M116.062240

PMCID:: PMC5098042

Abstract Article PDF–1.9M

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PMC Links for Gene (Select 131578) (30)
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Homo sapiens anaphase promoting complex subunit 15 (ANAPC15), transcript variant...
Homo sapiens anaphase promoting complex subunit 15 (ANAPC15), transcript variant 1, mRNA
gi|1677500966|ref|NM_001278485.2|

Nucleotide

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