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Select item 100236941.

DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice

Laura Senatus, Lander Egaña-Gorroño, Raquel López-Díez, Sonia Bergaya, Juan Francisco Aranda, Jaume Amengual, Lakshmi Arivazhagan, Michaele B. Manigrasso, Gautham Yepuri, Ramesh Nimma, Kaamashri N. Mangar, Rollanda Bernadin, Boyan Zhou, Paul F. Gugger, Huilin Li, Richard A. Friedman, Neil D. Theise, Alexander Shekhtman, Edward A. Fisher, Ravichandran Ramasamy, Ann Marie Schmidt

Commun Biol. 2023; 6: 280. Published online 2023 Mar 17. doi: 10.1038/s42003-023-04643-2

PMCID:: PMC10023694

Abstract Article PDF–3.7M

Select item 73714982.

Mechanochemical Coupling of Formin-induced Actin Interaction at the Level of Single Molecular Complex

Zhenhai Li, Hyunjung Lee, Suzanne G. Eskin, Shoichiro Ono, Cheng Zhu, Larry V. McIntire

Biomech Model Mechanobiol. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Biomech Model Mechanobiol. 2020 Oct; 19(5): 1509–1521. Published online 2020 Jan 21. doi: 10.1007/s10237-019-01284-5

PMCID:: PMC7371498

Abstract Article PDF–1.7M

Select item 72780823.

Mammalian diaphanous-related formin 1 (mDia1) coordinates mast cell migration and secretion through its actin-nucleating activity

Ofir Klein, Rebecca A. Krier-Burris, Pia Lazki-Hagenbach, Yaara Gorzalczany, Yang Mei, Peng Ji, Bruce S. Bochner, Ronit Sagi-Eisenberg

J Allergy Clin Immunol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: J Allergy Clin Immunol. 2019 Oct; 144(4): 1074–1090. Published online 2019 Jul 3. doi: 10.1016/j.jaci.2019.06.028

PMCID:: PMC7278082

Abstract Article PDF–1.2M

Select item 63369944.

Deletion of the formin Diaph1 protects from structural and functional abnormalities in the murine diabetic kidney

Michaele B. Manigrasso, Richard A. Friedman, Ravichandran Ramasamy, Vivette D’Agati, Ann Marie Schmidt

Am J Physiol Renal Physiol. 2018 Dec 1; 315(6): F1601–F1612. Published online 2018 Aug 22. doi: 10.1152/ajprenal.00075.2018

PMCID:: PMC6336994

Abstract Article

Select item 58814945.

Dia1-dependent adhesions are required by epithelial tissues to initiate invasion

Tim B. Fessenden, Yvonne Beckham, Mathew Perez-Neut, Guillermina Ramirez-San Juan, Aparajita H. Chourasia, Kay F. Macleod, Patrick W. Oakes, Margaret L. Gardel

J Cell Biol. 2018 Apr 2; 217(4): 1485–1502. doi: 10.1083/jcb.201703145

PMCID:: PMC5881494

Abstract Article PDF–3.4M

Select item 55403656.

Inhibition of diaphanous formin signaling in vivo impairs cardiovascular development and alters smooth muscle cell phenotype

Laura Weise-Cross, Joan M. Taylor, Christopher P. Mack

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Aug 2.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Nov; 35(11): 2374–2383. Published online 2015 Sep 17. doi: 10.1161/ATVBAHA.115.305879

PMCID:: PMC5540365

Abstract Article PDF–1.8M

Select item 41116647.

Formins as effector proteins of Rho GTPases

Sonja Kühn, Matthias Geyer

Small GTPases. 2014; 5: e29513. Published online 2014 Jun 10. doi: 10.4161/sgtp.29513

PMCID:: PMC4111664

Abstract Article PDF–3.6M

Select item 36967768.

Directing exocrine secretory vesicles to the apical membrane by actin cables generated by the formin mDia1

Erez Geron, Eyal D. Schejter, Ben-Zion Shilo

Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10652–10657. Published online 2013 Jun 10. doi: 10.1073/pnas.1303796110

PMCID:: PMC3696776

Abstract Article PDF–1.0M

Select item 34167469.

Structure and activity of full-length formin mDia1

Sankar Maiti, Alphee Michelot, Christopher Gould, Laurent Blanchoin, Olga Sokolova, Bruce L. Goode

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Cytoskeleton (Hoboken). 2012 Jun; 69(6): 393–405. doi: 10.1002/cm.21033

PMCID:: PMC3416746

Abstract Article PDF–2.6M

Select item 338190910.

The Formin mDia1 Mediates Vascular Remodeling via Integration of Oxidative & Signal Transduction Pathways

Fatouma Touré, Günter Fritz, Qing Li, Vivek Rai, Gurdip Daffu, Yu Shan Zou, Rosa Rosario, Ravichandran Ramasamy, Arthur S. Alberts, Shi Fang Yan, Ann Marie Schmidt

Circ Res. Author manuscript; available in PMC 2013 May 11.

Published in final edited form as: Circ Res. 2012 May 11; 110(10): 1279–1293. Published online 2012 Apr 17. doi: 10.1161/CIRCRESAHA.111.262519

PMCID:: PMC3381909

Abstract Article PDF–2.3M

Select item 294801911.

Crystal Structure of the Formin mDia1 in Autoinhibited Conformation

Takanori Otomo, Diana R. Tomchick, Chinatsu Otomo, Mischa Machius, Michael K. Rosen

PLoS One. 2010; 5(9): e12896. Published online 2010 Sep 30. doi: 10.1371/journal.pone.0012896

PMCID:: PMC2948019

Abstract Article PDF–4.9M

Select item 271129012.

The Uncoupling of the Effects of Formins on the Local and Global Dynamics of Actin Filaments

Tünde Kupi, Pál Gróf, Miklós Nyitrai, József Belágyi

Biophys J. 2009 Apr 8; 96(7): 2901–2911. doi: 10.1016/j.bpj.2008.11.058

PMCID:: PMC2711290

Abstract Article PDF–278K

Select item 211870513.

Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1

Daiji Sakata, Hiroyuki Taniguchi, Shingo Yasuda, Aki Adachi-Morishima, Yoko Hamazaki, Rika Nakayama, Takashi Miki, Nagahiro Minato, Shuh Narumiya

J Exp Med. 2007 Sep 3; 204(9): 2031–2038. doi: 10.1084/jem.20062647

PMCID:: PMC2118705

Abstract Article PDF–2.7M

Select item 135631814.

The regulation of mDia1 by autoinhibition and its release by Rho•GTP

Michael Lammers, Rolf Rose, Andrea Scrima, Alfred Wittinghofer

EMBO J. 2005 Dec 7; 24(23): 4176–4187. Published online 2005 Nov 17. doi: 10.1038/sj.emboj.7600879

PMCID:: PMC1356318

Abstract Article PDF–530K

Select item 13361615.

The Diaphanous-related Formin mDia1 Controls Serum Response Factor Activity through its Effects on Actin Polymerization

John W. Copeland, Richard Treisman

Mol Biol Cell. 2002 Nov; 13(11): 4088–4099. doi: 10.1091/mbc.02-06-0092

PMCID:: PMC133616

Abstract Article PDF–557K

Select item 863570716.

Loss of mDia1 and Fhod1 impacts platelet formation but not platelet function

Malou Zuidscherwoude, Elizabeth J. Haining, Victoria A. Simms, Stephanie Watson, Beata Grygielska, Alex T. Hardy, Andrea Bacon, Stephen P. Watson, Steven G. Thomas

Platelets. 2021; 32(8): 1051–1062. Published online 2020 Sep 27. doi: 10.1080/09537104.2020.1822522

PMCID:: PMC8635707

Abstract Article PDF–4.5M

Select item 736693317.

The integrity of cochlear hair cells is established and maintained through the localization of Dia1 at apical junctional complexes and stereocilia

Yuzuru Ninoyu, Hirofumi Sakaguchi, Chen Lin, Toshiaki Suzuki, Shigeru Hirano, Yasuo Hisa, Naoaki Saito, Takehiko Ueyama

Cell Death Dis. 2020 Jul; 11(7): 536. Published online 2020 Jul 16. doi: 10.1038/s41419-020-02743-z

PMCID:: PMC7366933

Abstract Article PDF–3.1M

Select item 617552918.

mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility

Satoko Sakamoto, Dean Thumkeo, Hiroshi Ohta, Zhen Zhang, Shuangru Huang, Pakorn Kanchanawong, Takayoshi Fuu, Sadanori Watanabe, Kentaro Shimada, Yoshitaka Fujihara, Shosei Yoshida, Masahito Ikawa, Naoki Watanabe, Mitinori Saitou, Shuh Narumiya

PLoS Biol. 2018 Sep; 16(9): e2004874. Published online 2018 Sep 26. doi: 10.1371/journal.pbio.2004874

PMCID:: PMC6175529

Abstract Article PDF–19M

Select item 588605719.

Y Mei, B Zhao, A A Basiorka, J Yang, L Cao, J Zhang, A List, P Ji

Leukemia. 2018 Apr; 32(4): 1023–1033. Prepublished online 2017 Nov 16. Published online 2018 Jan 5. doi: 10.1038/leu.2017.326

PMCID:: PMC5886057

Abstract Article PDF–1.8M

Select item 583256520.

The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury

Karen M. O'Shea, Radha Ananthakrishnan, Qing Li, Nosirudeen Quadri, Devi Thiagarajan, Gopalkrishna Sreejit, Lingjie Wang, Hylde Zirpoli, Juan Francisco Aranda, Arthur S. Alberts, Ann Marie Schmidt, Ravichandran Ramasamy

EBioMedicine. 2017 Dec; 26: 165–174. Published online 2017 Nov 21. doi: 10.1016/j.ebiom.2017.11.012

PMCID:: PMC5832565

Abstract Article PDF–1.0M

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