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Items: 1 to 20 of 33

1.
A novel autism-associated UBLCP1 mutation impacts proteasome regulation/activity
Jihane Soueid, Zeinab Hamze, Joe Bedran, Maria Chahrour, Rose-Mary Boustany
Transl Psychiatry. 2023; 13: 404. Published online 2023 Dec 21. doi: 10.1038/s41398-023-02702-0
PMCID:
PMC10739866
AbstractArticlePDF–17M
2.
Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function
Xiaoyan Liu, Weidi Xiao, Yanan Zhang, Sandra E. Wiley, Tao Zuo, Yingying Zheng, Natalie Chen, Lu Chen, Xiaorong Wang, Yawen Zheng, Lan Huang, Shixian Lin, Anne N. Murphy, Jack E. Dixon, Ping Xu, Xing Guo
Proc Natl Acad Sci U S A. 2020 Jan 7; 117(1): 328–336. Published online 2019 Dec 16. doi: 10.1073/pnas.1912531117
PMCID:
PMC6955308
AbstractArticlePDF–1.5M
3.
Solution Structure and Rpn1 Interaction of the UBL Domain of Human RNA Polymerase II C-Terminal Domain Phosphatase
Ji-Hye Yun, Sunggeon Ko, Chung-Kyung Lee, Hae-Kap Cheong, Chaejoon Cheong, Jong-Bok Yoon, Weontae Lee
PLoS One. 2013; 8(5): e62981. Published online 2013 May 7. doi: 10.1371/journal.pone.0062981
PMCID:
PMC3646893
AbstractArticlePDF–1.1M
4.
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity
Xing Guo, James L. Engel, Junyu Xiao, Vincent S. Tagliabracci, Xiaorong Wang, Lan Huang, Jack E. Dixon
Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46): 18649-18654. Published online 2011 Sep 26. doi: 10.1073/pnas.1113170108
PMCID:
PMC3219150
AbstractArticlePDF–1.7M
5.
UBASH3A regulates the synthesis and dynamics of T-cell receptor-CD3 complexes
Yan Ge, Taylor K. Paisie, Sixue Chen, Patrick Concannon
J Immunol. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: J Immunol. 2019 Dec 1; 203(11): 2827–2836. Published online 2019 Oct 28. doi: 10.4049/jimmunol.1801338
PMCID:
PMC6938261
AbstractArticlePDF–2.3M
6.
Phosphatase UBLCP1 controls proteasome assembly
Shuangwu Sun, Sisi Liu, Zhengmao Zhang, Wang Zeng, Chuang Sun, Tao Tao, Xia Lin, Xin-Hua Feng
Open Biol. 2017 May; 7(5): 170042. Published online 2017 May 24. doi: 10.1098/rsob.170042
PMCID:
PMC5451543
AbstractArticlePDF–1.6M
7.
Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes
Won Hoon Choi, Yejin Yun, Seoyoung Park, Jun Hyoung Jeon, Jeeyoung Lee, Jung Hoon Lee, Su-A Yang, Nak-Kyoon Kim, Chan Hoon Jung, Yong Tae Kwon, Dohyun Han, Sang Min Lim, Min Jae Lee
Proc Natl Acad Sci U S A. 2020 Aug 11; 117(32): 19190–19200. Published online 2020 Jul 28. doi: 10.1073/pnas.1920327117
PMCID:
PMC7430983
AbstractArticlePDF–2.2M
8.
Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome
Xiaorong Wang, Peter Cimermancic, Clinton Yu, Andreas Schweitzer, Nikita Chopra, James L. Engel, Charles Greenberg, Alexander S. Huszagh, Florian Beck, Eri Sakata, Yingying Yang, Eric J. Novitsky, Alexander Leitner, Paolo Nanni, Abdullah Kahraman, Xing Guo, Jack E. Dixon, Scott D. Rychnovsky, Ruedi Aebersold, Wolfgang Baumeister, Andrej Sali, Lan Huang
Mol Cell Proteomics. 2017 May; 16(5): 840–854. Published online 2017 Mar 14. doi: 10.1074/mcp.M116.065326
PMCID:
PMC5417825
AbstractArticlePDF–3.2M
9.
Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions
Aixin Song, Zachary Hazlett, Dulith Abeykoon, Jeremy Dortch, Andrew Dillon, Justin Curtiss, Sarah Bollinger Martinez, Christopher P Hill, Clinton Yu, Lan Huang, David Fushman, Robert E Cohen, Tingting Yao
eLife. 2021; 10: e72798. Published online 2021 Nov 11. doi: 10.7554/eLife.72798
PMCID:
PMC8635973
AbstractArticlePDF–10M
10.
Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates
Henrike C Besche, Zhe Sha, Nikolay V Kukushkin, Andreas Peth, Eva-Maria Hock, Woong Kim, Steven Gygi, Juan A Gutierrez, Hua Liao, Lawrence Dick, Alfred L Goldberg
EMBO J. 2014 May 16; 33(10): 1159–1176. Published online 2014 May 8. doi: 10.1002/embj.201386906
PMCID:
PMC4193922
AbstractArticlePDF–1.1M
11.
Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation
Clinton Yu, Yingying Yang, Xiaorong Wang, Shenheng Guan, Lei Fang, Fen Liu, Kylie J. Walters, Peter Kaiser, Lan Huang
Mol Cell Proteomics. 2016 Jul; 15(7): 2279–2292. Published online 2016 Apr 25. doi: 10.1074/mcp.M116.058271
PMCID:
PMC4937504
AbstractArticlePDF–1.5M
12.
Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles
Anja E. Eisenhardt, Adrian Sprenger, Michael Röring, Ricarda Herr, Florian Weinberg, Martin Köhler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, Jörn Dengjel, Tilman Brummer
Oncotarget. 2016 May 3; 7(18): 26628–26652. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8427
PMCID:
PMC5042004
AbstractArticlePDF–7.5M
13.
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase
Daniel C. Scott, Jared T. Hammill, Jaeki Min, David Y. Rhee, Michele Connelly, Vladislav O. Sviderskiy, Deepak Bhasin, Yizhe Chen, Su-Sien Ong, Sergio C. Chai, Asli N. Goktug, Guochang Huang, Julie K. Monda, Jonathan Low, Ho Shin Kim, Joao A. Paulo, Joe R. Cannon, Anang A. Shelat, Taosheng Chen, Ian R. Kelsall, Arno F. Alpi, Vishwajeeth Pagala, Xusheng Wang, Junmin Peng, Bhuvanesh Singh, J. Wade Harper, Brenda A. Schulman, R. Kip Guy
Nat Chem Biol. Author manuscript; available in PMC 2017 Dec 5.
Published in final edited form as: Nat Chem Biol. 2017 Aug; 13(8): 850–857. Published online 2017 Jun 5. doi: 10.1038/nchembio.2386
PMCID:
PMC5577376
AbstractArticlePDF–1.2M
14.
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak
Mol Cell. Author manuscript; available in PMC 2021 Jun 18.
Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027
PMCID:
PMC7306005
AbstractArticlePDF–3.2M
15.
Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull
PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606
PMCID:
PMC7392334
AbstractArticlePDF–2.7M
16.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
17.
The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang
J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009
PMCID:
PMC9058836
AbstractArticlePDF–2.9M
18.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
19.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
20.
A Census of Human Soluble Protein Complexes
Pierre C. Havugimana, G. Traver Hart, Tamás Nepusz, Haixuan Yang, Andrei L. Turinsky, Zhihua Li, Peggy I. Wang, Daniel R. Boutz, Vincent Fong, Sadhna Phanse, Mohan Babu, Stephanie A. Craig, Pingzhao Hu, Cuihong Wan, James Vlasblom, Vaqaarun-Nisa Dar, Alexander Bezginov, Gregory W. Clark, Gabriel C. Wu, Shoshana J. Wodak, Elisabeth R.M. Tillier, Alberto Paccanaro, Edward M. Marcotte, Andrew Emili
Cell. Author manuscript; available in PMC 2013 Aug 31.
Published in final edited form as: Cell. 2012 Aug 31; 150(5): 1068–1081. doi: 10.1016/j.cell.2012.08.011
PMCID:
PMC3477804
AbstractArticlePDF–7.7M

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