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Select item 101160811.

Identification and Characterization of chCR2, a Protein That Binds Chicken Complement Component 3d

Huan Jin, ZiMeng Kong, Bo Jiang, Min Tu, Jian Xu, Jing Cheng, Wenxiao Liu, Zhenhua Zhang, Yongqing Li

J Immunol. 2023 May 1; 210(9): 1408–1418. Published online 2023 Mar 24. doi: 10.4049/jimmunol.2200423

PMCID:: PMC10116081

Abstract Article PDF–2.6M

Select item 80473172.

Revisiting the Coreceptor Function of Complement Receptor Type 2 (CR2, CD21); Coengagement With the B-Cell Receptor Inhibits the Activation, Proliferation, and Antibody Production of Human B Cells

Kristóf G. Kovács, Bernadett Mácsik-Valent, János Matkó, Zsuzsa Bajtay, Anna Erdei

Front Immunol. 2021; 12: 620427. Published online 2021 Apr 1. doi: 10.3389/fimmu.2021.620427

PMCID:: PMC8047317

Abstract Article PDF–1.9M

Select item 72694323.

CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells

Nicholas A. Smith, Carrie B. Coleman, Benjamin E. Gewurz, Rosemary Rochford

J Virol. 2020 Jun; 94(11): e00428-20. Prepublished online 2020 Apr 1. Published online 2020 May 18. doi: 10.1128/JVI.00428-20

PMCID:: PMC7269432

Abstract Article PDF–1.6M

Select item 52156934.

Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

Iliana Michailidou, Daphne M. P. Naessens, Simon Hametner, Willemijn Guldenaar, Evert‐Jan Kooi, Jeroen J. G. Geurts, Frank Baas, Hans Lassmann, Valeria Ramaglia

Glia. 2017 Feb; 65(2): 264–277. Published online 2016 Oct 25. doi: 10.1002/glia.23090

PMCID:: PMC5215693

Abstract Article PDF–1.5M

Select item 50546945.

The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21)

Sanjay Khandelwal, Grace M. Lee, C. Garren Hester, Mortimer Poncz, Steven E. McKenzie, Bruce S. Sachais, Lubica Rauova, Garnett Kelsoe, Douglas B. Cines, Michael Frank, Gowthami M. Arepally

Blood. 2016 Oct 6; 128(14): 1789–1799. Prepublished online 2016 Jul 13. doi: 10.1182/blood-2016-04-709634

PMCID:: PMC5054694

Abstract Article

Select item 49440486.

Association of Complement Receptor 2 Gene Polymorphisms with Susceptibility to Osteonecrosis of the Femoral Head in Systemic Lupus Erythematosus

Tae-Ho Kim, Sang-Cheol Bae, Sang-Han Lee, Shin-Yoon Kim, Seung-Hoon Baek

Biomed Res Int. 2016; 2016: 9208035. Published online 2016 Jun 30. doi: 10.1155/2016/9208035

PMCID:: PMC4944048

Abstract Article PDF–620K

Select item 47417217.

A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL

Eva-Maria Nichols, Rachel Jones, Rachael Watson, Chris J. Pepper, Chris Fegan, Kevin J. Marchbank

Oncotarget. 2015 Oct 20; 6(32): 32669–32680. Published online 2015 Oct 3. doi: 10.18632/oncotarget.5404

PMCID:: PMC4741721

Abstract Article PDF–1.7M

Select item 47173928.

Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA

Jian Zhao, Brendan M Giles, Rhonda L Taylor, Gabriel A Yette, Kara M Lough, Han Leng Ng, Lawrence J Abraham, Hui Wu, Jennifer A Kelly, Stuart B Glenn, Adam J Adler, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda Marion, Marta E Alarcón-Riquelme, for the BIOLUPUS and GENLES Networks, Graciela S Alarcón, Juan-Manuel Anaya, Sang-Cheol Bae, Dam Kim, Hye-Soon Lee, Lindsey A Criswell, Barry I Freedman, Gary S Gilkeson, Joel M Guthridge, Chaim O Jacob, Judith A James, Diane L Kamen, Joan T Merrill, Kathy Moser Sivils, Timothy B Niewold, Michelle A Petri, Rosalind Ramsey-Goldman, John D Reveille, R Hal Scofield, Anne M Stevens, Luis M Vilá, Timothy J Vyse, Kenneth M Kaufman, John B Harley, Carl D Langefeld, Patrick M Gaffney, Elizabeth E Brown, Jeffrey C Edberg, Robert P Kimberly, Daniela Ulgiati, Betty P Tsao, Susan A Boackle

Ann Rheum Dis. 2016 Jan; 75(1): 242–252. Published online 2014 Sep 1. doi: 10.1136/annrheumdis-2014-205584

PMCID:: PMC4717392

Abstract Article PDF–1.8M

Select item 47116829.

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

Rhonda L Taylor, Mark N Cruickshank, Mahdad Karimi, Han Leng Ng, Elizabeth Quail, Kenneth M Kaufman, John B Harley, Lawrence J Abraham, Betty P Tsao, Susan A Boackle, Daniela Ulgiati

Cell Mol Immunol. 2016 Jan; 13(1): 119–131. Published online 2015 Feb 2. doi: 10.1038/cmi.2014.138

PMCID:: PMC4711682

Abstract Article PDF–3.1M

Select item 447919310.

Expansion of autoreactive unresponsive CD21^-/low B cells in Sjögren's syndrome associated lymphoproliferation

D Saadoun, B Terrier, J Bannock, T Vazquez, C Massad, I Kang, F Joly, M Rosenzwajg, D Sene, P Benech, D Klatzmann, E Meffre, P Cacoub

Arthritis Rheum. Author manuscript; available in PMC 2015 Jun 24.

Published in final edited form as: Arthritis Rheum. 2013 Apr; 65(4): 1085–1096. doi: 10.1002/art.37828

PMCID:: PMC4479193

Abstract Article PDF–605K

Select item 432399411.

C3d adjuvant effects are mediated through the activation of C3d-specific autoreactive T cells

Anne S. De Groot, Ted M. Ross, Lauren Levitz, Timothy J. Messitt, Ryan Tassone, Christine M. Boyle, Amber J. Vincelli, Leonard Moise, William Martin, Paul M. Knopf

Immunol Cell Biol. Author manuscript; available in PMC 2015 Aug 1.

Published in final edited form as: Immunol Cell Biol. 2015 Feb; 93(2): 189–197. Published online 2014 Nov 11. doi: 10.1038/icb.2014.89

PMCID:: PMC4323994

Abstract Article PDF–2.0M

Select item 401909112.

Analysis of Host Gene Expression Changes Reveals Distinct Roles for the Cytoplasmic Domain of the Epstein-Barr Virus Receptor/CD21 in B-Cell Maturation, Activation, and Initiation of Virus Infection

Mohamed S. Arredouani, Manoj K. Bhasin, David R. Sage, Laura K. Dunn, Michael B. Gill, Deep Agnani, Towia A. Libermann, Joyce D. Fingeroth

J Virol. 2014 May; 88(10): 5559–5577. doi: 10.1128/JVI.03099-13

PMCID:: PMC4019091

Abstract Article PDF–3.3M

Select item 396815213.

Impact of the Common Genetic Associations of Age-Related Macular Degeneration upon Systemic Complement Component C3d Levels

Tina Ristau, Constantin Paun, Lebriz Ersoy, Moritz Hahn, Yara Lechanteur, Carel Hoyng, Eiko K. de Jong, Mohamed R. Daha, Bernd Kirchhof, Anneke I. den Hollander, Sascha Fauser

PLoS One. 2014; 9(3): e93459. Published online 2014 Mar 27. doi: 10.1371/journal.pone.0093459

PMCID:: PMC3968152

Abstract Article PDF–213K

Select item 340124314.

Transcriptional effects of a lupus-associated polymorphism in the 5´ untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

Mark N. Cruickshank, Mahdad Karimi, Rhonda L. Mason, Emily Fenwick, Tim Mercer, Betty P. Tsao, Susan A. Boackle, Daniela Ulgiati

Mol Immunol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Mol Immunol. 2012 Oct; 52(3-4): 165–173. Published online 2012 Jun 4. doi: 10.1016/j.molimm.2012.04.013

PMCID:: PMC3401243

Abstract Article PDF–1.0M

Select item 293072415.

Biophysical Investigations of Complement Receptor 2 (CD21 and CR2)-Ligand Interactions Reveal Amino Acid Contacts Unique to Each Receptor-Ligand Pair

James M. Kovacs, Jonathan P. Hannan, Elan Z. Eisenmesser, V. Michael Holers

J Biol Chem. 2010 Aug 27; 285(35): 27251–27258. Published online 2010 Jun 17. doi: 10.1074/jbc.M110.106617

PMCID:: PMC2930724

Abstract Article PDF–1.3M

Select item 272634816.

Circulating CD21^low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

Mirzokhid Rakhmanov, Baerbel Keller, Sylvia Gutenberger, Christian Foerster, Manfred Hoenig, Gertjan Driessen, Mirjam van der Burg, Jacques J. van Dongen, Elisabeth Wiech, Marcella Visentini, Isabella Quinti, Antje Prasse, Nadine Voelxen, Ulrich Salzer, Sigune Goldacker, Paul Fisch, Hermann Eibel, Klaus Schwarz, Hans-Hartmut Peter, Klaus Warnatz

Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32): 13451–13456. Published online 2009 Jul 29. doi: 10.1073/pnas.0901984106

PMCID:: PMC2726348

Abstract Article PDF–1.0M

Select item 271440717.

Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing

Katherine B. Douglas, Daniel C. Windels, Jian Zhao, Agnessa V. Gadeliya, Hui Wu, Kenneth M. Kaufman, John B. Harley, Joan Merrill, Robert P. Kimberly, Graciela S. Alarcón, Elizabeth E. Brown, Jeffrey C. Edberg, Rosalind Ramsey-Goldman, Michelle Petri, John D. Reveille, Luis M. Vilá, Patrick M. Gaffney, Judith A. James, Kathy L. Moser, Marta E. Alarcón-Riquelme, Timothy J. Vyse, Gary S. Gilkeson, Chaim O. Jacob, Julie T. Ziegler, Carl D. Langefeld, Daniela Ulgiati, Betty P. Tsao, Susan A. Boackle

Genes Immun. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Genes Immun. 2009 Jul; 10(5): 457–469. Published online 2009 Apr 23. doi: 10.1038/gene.2009.27

Correction in:: volume 10 on page 606

PMCID:: PMC2714407

Abstract Article PDF–993K

Select item 265783118.

Increased B cell deletion and significantly reduced auto-antibody titre due to premature expression of human complement receptor 2 (CR2, CD21)

Isabel Y. Pappworth, Liudmila Kulik, Catherine Haluszczak, Jason W. Reuter, V. Michael Holers, Kevin J. Marchbank

Mol Immunol. 2009 Mar; 46(6): 1042–1049. doi: 10.1016/j.molimm.2008.08.273

PMCID:: PMC2657831

Abstract Article

Select item 219609519.

Follicular Dendritic Cells Specifically Express the Long CR2/CD21 Isoform

Yong-Jun Liu, Jiangchun Xu, Odette de Bouteiller, Christi L. Parham, Géraldine Grouard, Odile Djossou, Blandine de Saint-Vis, Serge Lebecque, Jacques Banchereau, Kevin W. Moore

J Exp Med. 1997 Jan 6; 185(1): 165–170. doi: 10.1084/jem.185.1.165

PMCID:: PMC2196095

Abstract Article PDF–416K

Select item 218889420.

Structure of the human B lymphocyte receptor for C3d and the Epstein- Barr virus and relatedness to other members of the family of C3/C4 binding proteins [published erratum appears in J Exp Med 1988 Nov 1;168(5):1953-4]

J Exp Med. 1988 Mar 1; 167(3): 1047–1066. doi: 10.1084/jem.167.3.1047

PMCID:: PMC2188894

Summary PDF–1.1M

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