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Select item 77602561.

Deletion of Exon 1 in AMER1 in Osteopathia Striata with Cranial Sclerosis

Jingyi Mi, Padmini Parthasarathy, Benjamin J. Halliday, Tim Morgan, John Dean, Malgorzata J. M. Nowaczyk, David Markie, Stephen P. Robertson, Emma M. Wade

Genes (Basel) 2020 Dec; 11(12): 1439. Published online 2020 Nov 30. doi: 10.3390/genes11121439

PMCID:: PMC7760256

Abstract Article PDF–627K

Select item 34167312.

WTX R353X mutation in a family with osteopathia striata and cranial sclerosis (OS-CS): case report and literature review of the disease clinical, genetic and radiological features

Anna Maria Zicari, Luigi Tarani, Daniela Perotti, Laura Papetti, Francesco Nicita, Natascia Liberati, Alberto Spalice, Guglielmo Salvatori, Federica Guaraldi, Marzia Duse

Ital J Pediatr. 2012; 38: 27. Published online 2012 Jun 20. doi: 10.1186/1824-7288-38-27

PMCID:: PMC3416731

Abstract Article PDF–511K

Select item 33101793.

The WTX tumor suppressor enhances p53 acetylation 9 by CBP/p300

Woo Jae Kim, Miguel N. Rivera, Erik J. Coffman, Daniel A. Haber

Mol Cell. Author manuscript; available in PMC 2012 Sep 9.

Published in final edited form as: Mol Cell. 2012 Mar 9; 45(5): 587–597. Published online 2012 Jan 26. doi: 10.1016/j.molcel.2011.12.025

PMCID:: PMC3310179

Abstract Article PDF–1.9M

Select item 29287944.

Mutations in the WTX - gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers

Silvio K Scheel, Marc Porzner, Sabine Pfeiffer, Steffen Ormanns, Thomas Kirchner, Andreas Jung

BMC Cancer. 2010; 10: 413. Published online 2010 Aug 9. doi: 10.1186/1471-2407-10-413

PMCID:: PMC2928794

Abstract Article PDF–685K

Select item 88122345.

IRF-2 inhibits cancer proliferation by promoting AMER-1 transcription in human gastric cancer

Yan-Jie Chen, Shu-Neng Luo, Hao Wu, Ning-Ping Zhang, Ling Dong, Tao-Tao Liu, Li Liang, Xi-Zhong Shen

J Transl Med. 2022; 20: 68. Published online 2022 Feb 3. doi: 10.1186/s12967-022-03275-0

PMCID:: PMC8812234

Abstract Article PDF–10M

Select item 72440356.

KIF23 activated Wnt/β-catenin signaling pathway through direct interaction with Amer1 in gastric cancer

Yi Liu, Hui Chen, Ping Dong, Guohua Xie, Yunlan Zhou, Yanhui Ma, Xiangliang Yuan, Junyao Yang, Li Han, Lei Chen, Lisong Shen

Aging (Albany NY) 2020 May 15; 12(9): 8372–8396. Published online 2020 May 4. doi: 10.18632/aging.103146

PMCID:: PMC7244035

Abstract Article PDF–3.3M

Select item 46092547.

Exome sequencing reveals AMER1 as a frequently mutated gene in colorectal cancer

Rebeca Sanz-Pamplona, Adriana Lopez-Doriga, Laia Paré-Brunet, Kira Lázaro, Fernando Bellido, M. Henar Alonso, Susanna Aussó, Elisabet Guinó, Sergi Beltrán, Francesc Castro-Giner, Marta Gut, Xavier Sanjuan, Adria Closa, David Cordero, Francisco D. Morón-Duran, Antonio Soriano, Ramón Salazar, Laura Valle, Victor Moreno

Clin Cancer Res. Author manuscript; available in PMC 2016 Oct 15.

Published in final edited form as: Clin Cancer Res. 2015 Oct 15; 21(20): 4709–4718. Published online 2015 Jun 12. doi: 10.1158/1078-0432.CCR-15-0159

PMCID:: PMC4609254

Abstract Article PDF–940K

Select item 31032998.

Structural and Functional Characterization of the Wnt Inhibitor APC Membrane Recruitment 1 (Amer1)

Kristina Tanneberger, Astrid S. Pfister, Vitezslav Kriz, Vitezslav Bryja, Alexandra Schambony, Jürgen Behrens

J Biol Chem. 2011 Jun 3; 286(22): 19204–19214. Published online 2011 Apr 15. doi: 10.1074/jbc.M111.224881

PMCID:: PMC3103299

Abstract Article PDF–3.1M

Select item 26770919.

The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity

Miguel N. Rivera, Woo Jae Kim, Julie Wells, Amanda Stone, Alexa Burger, Erik J. Coffman, Jianmin Zhang, Daniel A. Haber

Proc Natl Acad Sci U S A. 2009 May 19; 106(20): 8338–8343. Published online 2009 May 4. doi: 10.1073/pnas.0811349106

PMCID:: PMC2677091

Abstract Article PDF–1.6M

Select item 644551710.

MiR-4524b-5p/WTX/β-catenin axis functions as a regulator of metastasis in cervical cancer

Tong Li, Wenjuan Zhou, Yimin Li, Yaqi Gan, Yulong Peng, Qing Xiao, Chunli Ouyang, Anqi Wu, Sai Zhang, Jiaqi Liu, Lili Fan, Duo Han, Yu Wei, Guang Shu, Gang Yin

PLoS One. 2019; 14(4): e0214822. Published online 2019 Apr 2. doi: 10.1371/journal.pone.0214822

Correction in:: PLoS One. 2019; 14(12): e0226864.

PMCID:: PMC6445517

Abstract Article PDF–4.3M

Select item 433277211.

Wilms Tumor Genetics: Mutations in WT1, WTX, and CTNNB1 Account for Only About One-Third of Tumors

E. Cristy Ruteshouser, Stephen M. Robinson, Vicki Huff

Genes Chromosomes Cancer. Author manuscript; available in PMC 2015 Feb 18.

Published in final edited form as: Genes Chromosomes Cancer. 2008 Jun; 47(6): 461–470. doi: 10.1002/gcc.20553

PMCID:: PMC4332772

Abstract Article PDF–1.0M

Select item 294987012.

The WTX/AMER1 gene family: evolution, signature and function

Agnès Boutet, Glenda Comai, Andreas Schedl

BMC Evol Biol. 2010; 10: 280. Published online 2010 Sep 15. doi: 10.1186/1471-2148-10-280

PMCID:: PMC2949870

Abstract Article PDF–1.3M

Select item 388718013.

β-Arrestin Promotes Wnt-induced Low Density Lipoprotein Receptor-related Protein 6 (Lrp6) Phosphorylation via Increased Membrane Recruitment of Amer1 Protein

Vítězslav Kříž, Vendula Pospíchalová, Jan Mašek, Michaela Brita Christina Kilander, Josef Slavík, Kristina Tanneberger, Gunnar Schulte, Miroslav Machala, Alois Kozubík, Juergen Behrens, Vítězslav Bryja

J Biol Chem. 2014 Jan 10; 289(2): 1128–1141. Published online 2013 Nov 21. doi: 10.1074/jbc.M113.498444

PMCID:: PMC3887180

Abstract Article PDF–4.2M

Select item 310228014.

Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P₂ to LRP6 phosphorylation

Kristina Tanneberger, Astrid S Pfister, Katharina Brauburger, Jean Schneikert, Michel V Hadjihannas, Vitezslav Kriz, Gunnar Schulte, Vitezslav Bryja, Jürgen Behrens

EMBO J. 2011 Apr 20; 30(8): 1433–1443. Published online 2011 Feb 8. doi: 10.1038/emboj.2011.28

PMCID:: PMC3102280

Abstract Article PDF–1.2M

Select item 330731515.

Wilms Tumor Gene on X Chromosome (WTX) Inhibits Degradation of NRF2 Protein through Competitive Binding to KEAP1 Protein

Nathan D. Camp, Richard G. James, David W. Dawson, Feng Yan, James M. Davison, Scott A. Houck, Xiaobo Tang, Ning Zheng, Michael B. Major, Randall T. Moon

J Biol Chem. 2012 Feb 24; 287(9): 6539–6550. Published online 2012 Jan 3. doi: 10.1074/jbc.M111.316471

PMCID:: PMC3307315

Abstract Article PDF–1.9M

Select item 393250316.

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination

Bridgid E. Hast, Erica W. Cloer, Dennis Goldfarb, Heng Li, Priscila F. Siesser, Feng Yan, Vonn Walter, Ning Zheng, D. Neil Hayes, Michael B. Major

Cancer Res. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Cancer Res. 2014 Feb 1; 74(3): 808–817. Published online 2013 Dec 9. doi: 10.1158/0008-5472.CAN-13-1655

PMCID:: PMC3932503

Abstract Article PDF–4.1M

Select item 450550617.

The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28

Woo Jae Kim, Ben S. Wittner, Arnaud Amzallag, Brian W. Brannigan, David T. Ting, Sridhar Ramaswamy, Shyamala Maheswaran, Daniel A. Haber

J Biol Chem. 2015 Jun 5; 290(23): 14381–14390. Published online 2015 Apr 16. doi: 10.1074/jbc.M114.631945

PMCID:: PMC4505506

Abstract Article PDF–2.0M

Select item 266983718.

Genetic Mutations Associated With Cigarette Smoking in Pancreatic Cancer

Amanda Blackford, Giovanni Parmigiani, Thomas W. Kensler, Christopher Wolfgang, Siân Jones, Xiaosong Zhang, D. Willams Parsons, Jimmy Cheng-Ho Lin, Rebecca J. Leary, James R. Eshleman, Michael Goggins, Elizabeth M. Jaffee, Christine A. Iacobuzio-Donahue, Anirban Maitra, Alison Klein, John L. Cameron, Kelly Olino, Richard Schulick, Jordan Winter, Bert Vogelstein, Victor E. Velculescu, Kenneth W. Kinzler, Ralph H. Hruban

Cancer Res. Author manuscript; available in PMC 2010 Apr 15.

Published in final edited form as: Cancer Res. 2009 Apr 15; 69(8): 3681–3688. Published online 2009 Apr 7. doi: 10.1158/0008-5472.CAN-09-0015

PMCID:: PMC2669837

Abstract Article PDF–314K

Select item 705010319.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 429537520.

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

Tai Young Kim, Priscila F. Siesser, Kent L. Rossman, Dennis Goldfarb, Kathryn Mackinnon, Feng Yan, XianHua Yi, Michael J. MacCoss, Randall T. Moon, Channing J. Der, Michael B. Major

Mol Cell Biol. 2015 Jan; 35(1): 167–181. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00857-14

PMCID:: PMC4295375

Abstract Article PDF–5.6M

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PMC Links for Gene (Select 139285) (42)
PMC
Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member ...
Homo sapiens potassium voltage-gated channel, subfamily H (eag-related), member 2, mRNA (cDNA clone IMAGE:3510423), partial cds
gi|12804922|gb|BC001914.1|

Nucleotide
RecName: Full=B-lymphocyte antigen CD19; AltName: Full=B-lymphocyte surface anti...
RecName: Full=B-lymphocyte antigen CD19; AltName: Full=B-lymphocyte surface antigen B4; AltName: Full=Differentiation antigen CD19; AltName: Full=T-cell surface antigen Leu-12; AltName: CD_antigen=CD19; Flags: Precursor
gi|160332376|sp|P15391.6|CD19_HUMAN

Protein

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