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Select item 84534361.

The rs74794265 SNP of the SREK1 Gene is Associated with COPD in Kashi, China

Zulipikaer Abudureheman, Li Li, XueMei Zhong, JingRan Xu, Hui Gong, Subinuer Yilamujiang, Jie Ren, ChengXin Xie, AiFang Zheng, Dilala Tuerxun, Ayiguzali Abudukadeer, Paierda Aini, AiMin Xu, XiaoGuang Zou

Int J Chron Obstruct Pulmon Dis. 2021; 16: 2631–2636. Published online 2021 Sep 16. doi: 10.2147/COPD.S321150

PMCID:: PMC8453436

Abstract Article PDF–279K

Select item 30709112.

Analysis of SRrp86-regulated alternative splicing: Control of c-Jun and IκBβ activity

Amanda S Solis, James G Patton

RNA Biol. 2010 Jul-Aug; 7(4): 486–494. Published online 2010 Jul 1. doi: 10.4161/rna.7.4.11567

PMCID:: PMC3070911

Abstract Article PDF–16M

Select item 89271593.

The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma

Cunjie Chang, Muthukumar Rajasekaran, Yiting Qiao, Heng Dong, Yu Wang, Hongping Xia, Amudha Deivasigamani, Minjie Wu, Karthik Sekar, Hengjun Gao, Mengqing Sun, Yuqin Niu, Qian Li, Lin Tao, Zhen Yan, Menglan Wang, Shasha Chen, Shujuan Zhao, Dajing Chen, Lina Li, Fan Yang, Haojin Gao, Baodong Chen, Ling Su, Liang Xu, Ye Chen, Veerabrahma Pratap Seshachalam, Gongxing Chen, Jayantha Gunaratne, Wanjin Hong, Junping Shi, Gongying Chen, David S. Grierson, Benoit Chabot, Tian Xie, Kam Man Hui, Jianxiang Chen

Nat Commun. 2022; 13: 1363. Published online 2022 Mar 16. doi: 10.1038/s41467-022-29016-x

PMCID:: PMC8927159

Abstract Article PDF–16M

Select item 73634964.

Pathogenic SREK1 decrease in Huntington’s disease lowers TAF1 mimicking X-linked dystonia parkinsonism

Ivó H Hernández, Jorge R Cabrera, María Santos-Galindo, Manuel Sánchez-Martín, Verónica Domínguez, Ramón García-Escudero, María J Pérez-Álvarez, Belén Pintado, José J Lucas

Brain. 2020 Jul; 143(7): 2207–2219. Published online 2020 Jun 12. doi: 10.1093/brain/awaa150

PMCID:: PMC7363496

Abstract Article PDF–1.2M

Select item 13702735.

Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins.

Daron C Barnard, Jun Li, Rui Peng, James G Patton

RNA. 2002 Apr; 8(4): 526–533. doi: 10.1017/s1355838202029928

PMCID:: PMC1370273

Summary PDF–1.5M

Select item 855846.

Identification and Characterization of a Novel Serine-Arginine-Rich Splicing Regulatory Protein

Daron C. Barnard, James G. Patton

Mol Cell Biol. 2000 May; 20(9): 3049–3057. doi: 10.1128/mcb.20.9.3049-3057.2000

PMCID:: PMC85584

Abstract Article PDF–1.6M

Select item 13703417.

PSF and p54nrb bind a conserved stem in U5 snRNA.

Rui Peng, Billy T Dye, Ismael Pérez, Daron C Barnard, Amanda B Thompson, James G Patton

RNA. 2002 Oct; 8(10): 1334–1347. doi: 10.1017/s1355838202022070

PMCID:: PMC1370341

Summary PDF–555K

Select item 1866338.

Large-Scale Proteomic Analysis of the Human Spliceosome

Juri Rappsilber, Ursula Ryder, Angus I. Lamond, Matthias Mann

Genome Res. 2002 Aug; 12(8): 1231–1245. doi: 10.1101/gr.473902

PMCID:: PMC186633

Abstract Article PDF–428K

Select item 2076169.

Regulation of Alternative Splicing by SRrp86 and Its Interacting Proteins

Jun Li, Ian C. Hawkins, Christopher D. Harvey, Jennifer L. Jennings, Andrew J. Link, James G. Patton

Mol Cell Biol. 2003 Nov; 23(21): 7437–7447. doi: 10.1128/MCB.23.21.7437-7447.2003

PMCID:: PMC207616

Abstract Article PDF–399K

Select item 381740410.

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities

Franco J Vizeacoumar, Roland Arnold, Frederick S Vizeacoumar, Megha Chandrashekhar, Alla Buzina, Jordan T F Young, Julian H M Kwan, Azin Sayad, Patricia Mero, Steffen Lawo, Hiromasa Tanaka, Kevin R Brown, Anastasia Baryshnikova, Anthony B Mak, Yaroslav Fedyshyn, Yadong Wang, Glauber C Brito, Dahlia Kasimer, Taras Makhnevych, Troy Ketela, Alessandro Datti, Mohan Babu, Andrew Emili, Laurence Pelletier, Jeff Wrana, Zev Wainberg, Philip M Kim, Robert Rottapel, Catherine A O’Brien, Brenda Andrews, Charles Boone, Jason Moffat

Mol Syst Biol. 2013; 9: 696. Published online 2013 Oct 8. doi: 10.1038/msb.2013.54

PMCID:: PMC3817404

Abstract Article PDF–13M

Select item 282753811.

A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks

Etsuko Miyamoto-Sato, Shigeo Fujimori, Masamichi Ishizaka, Naoya Hirai, Kazuyo Masuoka, Rintaro Saito, Yosuke Ozawa, Katsuya Hino, Takanori Washio, Masaru Tomita, Tatsuhiro Yamashita, Tomohiro Oshikubo, Hidetoshi Akasaka, Jun Sugiyama, Yasuo Matsumoto, Hiroshi Yanagawa

PLoS One. 2010; 5(2): e9289. Published online 2010 Feb 24. doi: 10.1371/journal.pone.0009289

PMCID:: PMC2827538

Abstract Article PDF–676K

Select item 816786612.

Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb‐202 in gastric cancer

Hitomi Sakai, Hisato Kawakami, Takeshi Teramura, Yuta Onodera, Elizabeth Somers, Keiji Furuuchi, Toshimitsu Uenaka, Ryoji Kato, Kazuhiko Nakagawa

Clin Transl Med. 2021 Jun; 11(6): e454. Published online 2021 Jun 1. doi: 10.1002/ctm2.454

PMCID:: PMC8167866

Abstract Article PDF–7.0M

Select item 584026613.

Insights into the ubiquitin-proteasome system of human embryonic stem cells

Isabel Saez, Seda Koyuncu, Ricardo Gutierrez-Garcia, Christoph Dieterich, David Vilchez

Sci Rep. 2018; 8: 4092. Published online 2018 Mar 6. doi: 10.1038/s41598-018-22384-9

PMCID:: PMC5840266

Abstract Article PDF–2.9M

Select item 546003514.

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

Philippe Cloutier, Christian Poitras, Mathieu Durand, Omid Hekmat, Émilie Fiola-Masson, Annie Bouchard, Denis Faubert, Benoit Chabot, Benoit Coulombe

Nat Commun. 2017; 8: 15615. Published online 2017 May 31. doi: 10.1038/ncomms15615

PMCID:: PMC5460035

Abstract Article PDF–2.9M

Select item 402487815.

TRIM65 regulates microRNA activity by ubiquitination of TNRC6

Shitao Li, Lingyan Wang, Bishi Fu, Michael A. Berman, Alos Diallo, Martin E. Dorf

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 6970–6975. Published online 2014 Apr 28. doi: 10.1073/pnas.1322545111

PMCID:: PMC4024878

Abstract Article PDF–1.1M

Select item 962912116.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 988113617.

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke

Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188

PMCID:: PMC9881136

Abstract Article PDF–4.4M

Select item 992246818.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 289232019.

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

David Llères, Marco Denegri, Marco Biggiogera, Paul Ajuh, Angus I Lamond

EMBO Rep. 2010 Jun; 11(6): 445–451. Published online 2010 May 14. doi: 10.1038/embor.2010.64

PMCID:: PMC2892320

Abstract Article PDF–895K

Select item 943756320.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

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PMC Links for Gene (Select 140890) (55)
PMC
PREDICTED: Homo sapiens zinc finger and BTB domain containing 1 (ZBTB1), transcr...
PREDICTED: Homo sapiens zinc finger and BTB domain containing 1 (ZBTB1), transcript variant X3, mRNA
gi|2462539249|ref|XM_054375583.1|

Nucleotide
Homo sapiens zinc finger and BTB domain containing 1 (ZBTB1), transcript variant...
Homo sapiens zinc finger and BTB domain containing 1 (ZBTB1), transcript variant 2, mRNA
gi|1677531278|ref|NM_014950.3|

Nucleotide

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