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Select item 5565941.

Comparison of mouse and human HOX-4 complexes defines conserved sequences involved in the regulation of Hox-4.4.

A Renucci, V Zappavigna, J Zàkàny, J C Izpisúa-Belmonte, K Bürki, D Duboule

EMBO J. 1992 Apr; 11(4): 1459–1468. doi: 10.1002/j.1460-2075.1992.tb05190.x

PMCID:: PMC556594

Summary Page Browse PDF–3.6M

Select item 5237722.

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements.

T Dalton, R D Palmiter, G K Andrews

Nucleic Acids Res. 1994 Nov 25; 22(23): 5016–5023. doi: 10.1093/nar/22.23.5016

PMCID:: PMC523772

Summary Page Browse PDF–1.8M

Select item 4009823.

Two gene members of the murine HOX-5 complex show regional and cell-type specific expression in developing limbs and gonads.

P Dollé, D Duboule

EMBO J. 1989 May; 8(5): 1507–1515. doi: 10.1002/j.1460-2075.1989.tb03535.x

PMCID:: PMC400982

Summary Page Browse PDF–3.1M

Select item 4529184.

J C Izpisúa-Belmonte, H Falkenstein, P Dollé, A Renucci, D Duboule

EMBO J. 1991 Aug; 10(8): 2279–2289. doi: 10.1002/j.1460-2075.1991.tb07764.x

PMCID:: PMC452918

Summary Page Browse PDF–3.0M

Select item 22233175.

Identification and Analysis of a Conserved Tcfap2a Intronic Enhancer Element Required for Expression in Facial and Limb Bud Mesenchyme

Weiguo Feng, Jian Huang, Jian Zhang, Trevor Williams

Mol Cell Biol. 2008 Jan; 28(1): 315–325. Published online 2007 Nov 5. doi: 10.1128/MCB.01168-07

PMCID:: PMC2223317

Abstract Article PDF–688K

Select item 93079946.

Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken

Aurélie Hintermann, Isabel Guerreiro, Lucille Lopez-Delisle, Christopher Chase Bolt, Sandra Gitto, Denis Duboule, Leonardo Beccari

Development. 2022 Jun 15; 149(12): dev200594. Published online 2022 Jun 30. doi: 10.1242/dev.200594

PMCID:: PMC9307994

Abstract Article

Select item 92058577.

Context-dependent enhancer function revealed by targeted inter-TAD relocation

Christopher Chase Bolt, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez, Antonella Rauseo, Guillaume Andrey, Denis Duboule

Nat Commun. 2022; 13: 3488. Published online 2022 Jun 17. doi: 10.1038/s41467-022-31241-3

PMCID:: PMC9205857

Abstract Article PDF–2.3M

Select item 85596748.

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

Ana Rita Amândio, Leonardo Beccari, Lucille Lopez-Delisle, Bénédicte Mascrez, Jozsef Zakany, Sandra Gitto, Denis Duboule

Genes Dev. 2021 Nov 1; 35(21-22): 1490–1509. doi: 10.1101/gad.348934.121

PMCID:: PMC8559674

Abstract Article PDF–22M

Select item 77338579.

Chromatin topology and the timing of enhancer function at the HoxD locus

Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Andréa Willemin, Leonardo Beccari, Sandra Gitto, Bénédicte Mascrez, Denis Duboule

Proc Natl Acad Sci U S A. 2020 Dec 8; 117(49): 31231–31241. Published online 2020 Nov 23. doi: 10.1073/pnas.2015083117

PMCID:: PMC7733857

Abstract Article PDF–2.5M

Select item 661314710.

The constrained architecture of mammalian Hox gene clusters

Fabrice Darbellay, Célia Bochaton, Lucille Lopez-Delisle, Bénédicte Mascrez, Patrick Tschopp, Saskia Delpretti, Jozsef Zakany, Denis Duboule

Proc Natl Acad Sci U S A. 2019 Jul 2; 116(27): 13424–13433. Published online 2019 Jun 17. doi: 10.1073/pnas.1904602116

PMCID:: PMC6613147

Abstract Article PDF–2.5M

Select item 40098011.

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

D Duboule, P Dollé

EMBO J. 1989 May; 8(5): 1497–1505. doi: 10.1002/j.1460-2075.1989.tb03534.x

PMCID:: PMC400980

Summary Page Browse PDF–2.4M

Select item 837393112.

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Christopher Chase Bolt, Lucille Lopez-Delisle, Bénédicte Mascrez, Denis Duboule

Nat Commun. 2021; 12: 5013. Published online 2021 Aug 18. doi: 10.1038/s41467-021-25330-y

PMCID:: PMC8373931

Abstract Article PDF–3.1M

Select item 1517213.

Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy

Feng Chen, Mario R. Capecchi

Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2): 541–546. doi: 10.1073/pnas.96.2.541

PMCID:: PMC15172

Abstract Article PDF–994K

Select item 264267014.

Uncoupling Time and Space in the Collinear Regulation of Hox Genes

Patrick Tschopp, Basile Tarchini, François Spitz, Jozsef Zakany, Denis Duboule

PLoS Genet. 2009 Mar; 5(3): e1000398. Published online 2009 Mar 6. doi: 10.1371/journal.pgen.1000398

PMCID:: PMC2642670

Abstract Article PDF–3.9M

Select item 221669415.

Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness

Thomas Montavon, Jean-François Le Garrec, Michel Kerszberg, Denis Duboule

Genes Dev. 2008 Feb 1; 22(3): 346–359. doi: 10.1101/gad.1631708

PMCID:: PMC2216694

Abstract Article PDF–798K

Select item 662636416.

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Nayuta Yakushiji-Kaminatsui, Asier Ullate-Agote, Denis Duboule

BMC Biol. 2019; 17: 55. Published online 2019 Jul 12. doi: 10.1186/s12915-019-0677-x

PMCID:: PMC6626364

Abstract Article PDF–1.9M

Select item 422415617.

Genetic Interactions Between Shox2 and Hox Genes During the Regional Growth and Development of the Mouse Limb

Stanley J. Neufeld, Fan Wang, John Cobb

Genetics. 2014 Nov; 198(3): 1117–1126. Published online 2014 Sep 11. doi: 10.1534/genetics.114.167460

PMCID:: PMC4224156

Abstract Article PDF–1.8M

Select item 448267218.

“Self-Regulation,” A New Facet of Hox Genes’ Function

Rushikesh Sheth, Maria Félix Bastida, Marie Kmita, Marian Ros

Dev Dyn. Author manuscript; available in PMC 2015 Jun 26.

Published in final edited form as: Dev Dyn. 2014 Jan; 243(1): 182–191. Published online 2013 Sep 2. doi: 10.1002/dvdy.24019

PMCID:: PMC4482672

Abstract Article PDF–1.0M

Select item 31277219.

Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations

François Spitz, Federico Gonzalez, Catherine Peichel, Thomas F. Vogt, Denis Duboule, József Zákány

Genes Dev. 2001 Sep 1; 15(17): 2209–2214. doi: 10.1101/gad.205701

PMCID:: PMC312772

Abstract Article PDF–533K

Select item 310275020.

Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human

Patrick Schorderet, Denis Duboule

PLoS Genet. 2011 May; 7(5): e1002071. Published online 2011 May 26. doi: 10.1371/journal.pgen.1002071

PMCID:: PMC3102750

Abstract Article PDF–1.4M

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PMC Links for Gene (Select 15438) (50)
PMC
pro-neuregulin-3, membrane-bound isoform isoform X2 [Homo sapiens]
pro-neuregulin-3, membrane-bound isoform isoform X2 [Homo sapiens]
gi|1034566157|ref|XP_016871063.1|

Protein
PREDICTED: Homo sapiens neuregulin 3 (NRG3), transcript variant X2, mRNA
PREDICTED: Homo sapiens neuregulin 3 (NRG3), transcript variant X2, mRNA
gi|2217275225|ref|XM_017015574.3|

Nucleotide

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