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Items: 18

Select item 50768281.

Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases

Ling Liu, Yu Wei Phua, Rachel S. Lee, Xiuquan Ma, Yiping Jenkins, Karel Novy, Emily S. Humphrey, Howard Chan, Robert Shearer, Poh Chee Ong, Weiwen Dai, Darren N. Saunders, Isabelle S. Lucet, Roger J. Daly

J Biol Chem. 2016 Oct 7; 291(41): 21571–21583. Published online 2016 Aug 16. doi: 10.1074/jbc.M116.748897

PMCID:: PMC5076828

Abstract Article PDF–2.2M

Select item 106472202.

Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study

Anastasiia A. Buianova, Mariia V. Proskura, Valery V. Cheranev, Vera A. Belova, Anna O. Shmitko, Anna S. Pavlova, Iuliia A. Vasiliadis, Oleg N. Suchalko, Denis V. Rebrikov, Edita K. Petrosyan, Dmitriy O. Korostin

Int J Mol Sci. 2023 Nov; 24(21): 15984. Published online 2023 Nov 5. doi: 10.3390/ijms242115984

PMCID:: PMC10647220

Abstract Article PDF–3.7M

Select item 56600933.

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association

Onisha Patel, Michael D. W. Griffin, Santosh Panjikar, Weiwen Dai, Xiuquan Ma, Howard Chan, Celine Zheng, Ashleigh Kropp, James M. Murphy, Roger J. Daly, Isabelle S. Lucet

Nat Commun. 2017; 8: 1157. Published online 2017 Oct 27. doi: 10.1038/s41467-017-01279-9

PMCID:: PMC5660093

Abstract Article PDF–2.3M

Select item 45176514.

The pseudokinase SgK223 promotes invasion of pancreatic ductal epithelial cells through JAK1/Stat3 signaling

Carole M. Tactacan, Yu Wei Phua, Ling Liu, Luxi Zhang, Emily S. Humphrey, Mark Cowley, Mark Pinese, Andrew V. Biankin, Roger J. Daly

Mol Cancer. 2015; 14: 139. Published online 2015 Jul 29. doi: 10.1186/s12943-015-0412-3

PMCID:: PMC4517651

Abstract Article PDF–1.9M

Select item 31691395.

Mammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors

Fatemeh Safari, Naoko Murata-Kamiya, Yasuhiro Saito, Masanori Hatakeyama

Proc Natl Acad Sci U S A. 2011 Sep 6; 108(36): 14938–14943. Published online 2011 Aug 22. doi: 10.1073/pnas.1107740108

PMCID:: PMC3169139

Abstract Article PDF–625K

Select item 49467046.

C‐terminal Src kinase‐mediated EPIYA phosphorylation of Pragmin creates a feed‐forward C‐terminal Src kinase activation loop that promotes cell motility

Yoshie Senda, Naoko Murata‐Kamiya, Masanori Hatakeyama

Cancer Sci. 2016 Jul; 107(7): 972–980. Published online 2016 Jun 13. doi: 10.1111/cas.12962

PMCID:: PMC4946704

Abstract Article PDF–1.4M

Select item 41549947.

NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis

Kelly L. Weaver, Marie-Clotilde Alves-Guerra, Ke Jin, Zhiqiang Wang, Xiaoqing Han, Prathibha Ranganathan, Xiaoxia Zhu, Thiago DaSilva, Wei Liu, Francesca Ratti, Renee M. Demarest, Cristos Tzimas, Meghan Rice, Rodrigo Vasquez-Del Carpio, Nadia Dahmane, David J. Robbins, Anthony J. Capobianco

Cancer Res. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Cancer Res. 2014 Sep 1; 74(17): 4741–4751. Published online 2014 Jul 18. doi: 10.1158/0008-5472.CAN-14-1547

PMCID:: PMC4154994

Abstract Article PDF–878K

Select item 38947868.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Abstract Article PDF–5.0M

Select item 100729069.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 926261410.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 698120611.

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS^G13D

Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch

Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9

PMCID:: PMC6981206

Abstract Article PDF–3.7M

Select item 910523512.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 583915813.

Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells

Giorgio Giurato, Giovanni Nassa, Annamaria Salvati, Elena Alexandrova, Francesca Rizzo, Tuula A. Nyman, Alessandro Weisz, Roberta Tarallo

Sci Data. 2018; 5: 180031. Published online 2018 Mar 6. doi: 10.1038/sdata.2018.31

PMCID:: PMC5839158

Abstract Article PDF–1.9M

Select item 582692614.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 289646415.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 1023742216.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011