PMC Links for Gene (Select 1576) - PMC

Melissa Gonzalez Veiga, Rogério Tadeu Felizi, Dayane Guerino Reis, Ivo Carelli Filho, Cesar Eduardo Fernandes, Ricardo Peres do Souto, Emerson Oliveira

Rev Bras Ginecol Obstet. 2018 Nov; 40(11): 699–704. Published online 2018 Oct 18. doi: 10.1055/s-0038-1673365

PMCID:: PMC10309480

Abstract Article PDF–218K

Select item 97282675.

Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4

Marie Yamada, Koji Hatsuta, Mayuko Niikawa, Hiromasa Imaishi

J Microbiol Biotechnol. 2020 Aug 28; 30(8): 1207–1213. Published online 2020 May 13. doi: 10.4014/jmb.2003.03032

PMCID:: PMC9728267

Abstract Article PDF–772K

Select item 96044836.

Crystal Structure of CYP3A4 Complexed with Fluorol Identifies the Substrate Access Channel as a High-Affinity Ligand Binding Site

Irina F. Sevrioukova

Int J Mol Sci. 2022 Oct; 23(20): 12591. Published online 2022 Oct 20. doi: 10.3390/ijms232012591

PMCID:: PMC9604483

Abstract Article PDF–3.2M

Select item 92727027.

Tacrolimus CYP3A Single-Nucleotide Polymorphisms and Preformed T- and B-Cell Alloimmune Memory Improve Current Pretransplant Rejection-Risk Stratification in Kidney Transplantation

Elena Crespo, Anna Vidal-Alabró, Thomas Jouve, Pere Fontova, Maik Stein, Sonila Mocka, Maria Meneghini, Anett Sefrin, Petra Hruba, Montserrat Gomà, Alba Torija, Laura Donadeu, Alex Favà, Josep M. Cruzado, Edoardo Melilli, Francesc Moreso, Ondrej Viklicky, Frederike Bemelman, Petra Reinke, Josep Grinyó, Nuria Lloberas, Oriol Bestard

Front Immunol. 2022; 13: 869554. Published online 2022 Jun 27. doi: 10.3389/fimmu.2022.869554

PMCID:: PMC9272702

Abstract Article PDF–3.4M

Select item 88579408.

Midazolam as a Probe for Drug–Drug Interactions Mediated by CYP3A4: Homotropic Allosteric Mechanism of Site-Specific Hydroxylation

Ilia G. Denisov, Yelena V. Grinkova, Tyler Camp, Mark A. McLean, Stephen G. Sligar

Biochemistry. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Biochemistry. 2021 Jun 1; 60(21): 1670–1681. Published online 2021 May 20. doi: 10.1021/acs.biochem.1c00161

PMCID:: PMC8857940

Abstract Article PDF–1.7M

Select item 83015639.

Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function

Alison E. Fohner, Rachel Dalton, Kasse Skagen, Konner Jackson, Katrina G. Claw, Scarlett E. Hopkins, Renee Robinson, Burhan A. Khan, Bhagwat Prasad, Erin G. Schuetz, Deborah A. Nickerson, Timothy A. Thornton, Denise A. Dillard, Bert B. Boyer, Kenneth E. Thummel, Erica L. Woodahl

Clin Transl Sci. 2021 Jul; 14(4): 1292–1302. Published online 2021 Jan 27. doi: 10.1111/cts.12970

PMCID:: PMC8301563

Abstract Article PDF–313K

Select item 827838410.

Homotropic Cooperativity of Midazolam Metabolism by Cytochrome P450 3A4: Insight from Computational Studies

Junhao Li, Yue Chen, Yun Tang, Weihua Li, Yaoquan Tu

J Chem Inf Model. 2021 May 24; 61(5): 2418–2426. Published online 2021 Apr 22. doi: 10.1021/acs.jcim.1c00266

PMCID:: PMC8278384

Abstract Article PDF–4.6M

Select item 814405911.

Comparison of the inhibitory effects of azole antifungals on cytochrome P450 3A4 genetic variants

Yuki Yamaguchi, Takeshi Akiyoshi, Go Kawamura, Ayuko Imaoka, Mitsue Miyazaki, F. Peter Guengerich, Katsunori Nakamura, Koujirou Yamamoto, Hisakazu Ohtani

Drug Metab Pharmacokinet. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Drug Metab Pharmacokinet. 2021 Jun; 38: 100384. Published online 2021 Jan 22. doi: 10.1016/j.dmpk.2021.100384

PMCID:: PMC8144059

Abstract Article PDF–497K

Select item 799328312.

Effect of Crohn’s Disease on Villous Length and CYP3A4 Expression in the Pediatric Small Intestine

Carrie A Vyhlidal, Brian D. Chapron, Atif Ahmed, Vivekanand Singh, Rebecca Casini, Valentina Shakhnovich

Clin Transl Sci. 2021 Mar; 14(2): 729–736. Published online 2020 Dec 16. doi: 10.1111/cts.12938

PMCID:: PMC7993283

Abstract Article PDF–315K

Select item 782763413.

Effect of Microbial Short-Chain Fatty Acids on CYP3A4-Mediated Metabolic Activation of Human Pluripotent Stem Cell-Derived Liver Organoids

Seon Ju Mun, Jaeseo Lee, Kyung-Sook Chung, Mi-Young Son, Myung Jin Son

Cells. 2021 Jan; 10(1): 126. Published online 2021 Jan 11. doi: 10.3390/cells10010126

PMCID:: PMC7827634

Abstract Article PDF–2.0M

Select item 771823014.

Association of clozapine-related metabolic disturbances with CYP3A4 expression in patients with schizophrenia

Ádám Menus, Ádám Kiss, Katalin Tóth, Dávid Sirok, Máté Déri, Ferenc Fekete, Gábor Csukly, Katalin Monostory

Sci Rep. 2020; 10: 21283. Published online 2020 Dec 4. doi: 10.1038/s41598-020-78474-0

PMCID:: PMC7718230

Abstract Article PDF–1.1M

Select item 765321115.

A new parameter in multiple myeloma: CYP3A4*1B single nucleotide polymorphism

Istemi Serin, Sacide Pehlivan, Ilknur Gundes, Yasemin Fidan Oyaci, Mustafa Pehlivan

Ann Hematol. 2021; 100(2): 421–427. Published online 2020 Nov 10. doi: 10.1007/s00277-020-04339-1

PMCID:: PMC7653211

Abstract Article PDF–414K

Select item 706584916.

Nonalcoholic fatty liver disease and diabetes is associated with decreased CYP3A4 protein expression and activity in human liver

Rohitash Jamwal, Suzanne M. de la Monte, Ken Ogasawara, Sravani Adusumalli, Benjamin B Barlock, Fatemeh Akhlaghi

Mol Pharm. Author manuscript; available in PMC 2020 Mar 11.

Published in final edited form as: Mol Pharm. 2018 Jul 2; 15(7): 2621–2632. Published online 2018 Jun 11. doi: 10.1021/acs.molpharmaceut.8b00159

PMCID:: PMC7065849

Abstract Article PDF–1012K

Select item 685468517.

Neurovascular drug biotransformation machinery in focal human epilepsies: Brain CYP3A4 correlates with seizure frequency and antiepileptic drug therapy

Sherice Williams, Mohammed Hossain, Lisa Ferguson, Robyn M. Busch, Nicola Marchi, Jorge Gonzalez-Martinez, Emilio Perucca, Imad M. Najm, Chaitali Ghosh

Mol Neurobiol. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Mol Neurobiol. 2019 Dec; 56(12): 8392–8407. Published online 2019 Jun 26. doi: 10.1007/s12035-019-01673-y

PMCID:: PMC6854685

Abstract Article PDF–3.0M

Select item 676949118.

Molecular Dynamics Simulation Framework to Probe the Binding Hypothesis of CYP3A4 Inhibitors

Yusra Sajid Kiani, Kara E. Ranaghan, Ishrat Jabeen, Adrian J. Mulholland

Int J Mol Sci. 2019 Sep; 20(18): 4468. Published online 2019 Sep 10. doi: 10.3390/ijms20184468

PMCID:: PMC6769491

Abstract Article PDF–2.6M

Select item 661974619.

Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C

Keizo Kato, Noritomo Shimada, Masanori Atsukawa, Hiroshi Abe, Norio Itokawa, Yoshihiro Matsumoto, Rie Agata, Akihito Tsubota

PLoS One. 2019; 14(7): e0219022. Published online 2019 Jul 10. doi: 10.1371/journal.pone.0219022

PMCID:: PMC6619746

Abstract Article PDF–1.1M

Select item 656554220.

Estimation of CYP3A4*1B single nucleotide polymorphism in patients with recurrent Major Depressive Disorder

Rafał Świechowski, Agnieszka Jeleń, Marek Mirowski, Monika Talarowska, Piotr Gałecki, Jacek Pietrzak, Damian Wodziński, Ewa Balcerczak

Mol Genet Genomic Med. 2019 Jun; 7(6): e669. Published online 2019 Apr 25. doi: 10.1002/mgg3.669

PMCID:: PMC6565542

Abstract Article PDF–461K

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