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Select item 109385211.

Identification of a Novel CYP11B2 Variant in a Family with Varying Degrees of Aldosterone Synthase Deficiency

Mark R. Garrelfs, Tuula Rinne, Jacquelien J. Hillebrand, Peter Lauffer, Merijn W. Bijlsma, Hedi L. Claahsen-van der Grinten, Nicole de Leeuw, Martijn J.J. Finken, Joost Rotteveel, Nitash Zwaveling-Soonawala, Max Nieuwdorp, A.S. Paul van Trotsenburg, Christiaan F. Mooij

J Clin Res Pediatr Endocrinol. 2024 Mar; 16(1): 95–101. Published online 2024 Mar 11. doi: 10.4274/jcrpe.galenos.2022.2022-3-4

PMCID:: PMC10938521

Abstract Article PDF–552K

Select item 102978982.

Association between Aldosterone Synthase (CYP11B2) Gene Polymorphism and Hypertension in Pashtun Ethnic Population of Khyber Pakhtunkwha, Pakistan

Waheed Ali Shah, Asif Jan, Muhammad Asghar Khan, Muhammad Saeed, Naveed Rahman, Zakiullah, Muhammad Sajjad Afridi, Fazli Khuda, Rani Akbar

Genes (Basel) 2023 Jun; 14(6): 1184. Published online 2023 May 29. doi: 10.3390/genes14061184

PMCID:: PMC10297898

Abstract Article PDF–581K

Select item 81863403.

Clinical and Genetic Characteristics of Patients with Corticosterone Methyloxidase Deficiency Type 2: Novel Mutations in CYP11B2

Hande Turan, Aydilek Dağdeviren Çakır, Yavuz Özer, Gürkan Tarçın, Bahar Özcabi, Serdar Ceylaner, Oya Ercan, Saadet Olcay Evliyaoğlu

J Clin Res Pediatr Endocrinol. 2021 Jun; 13(2): 232–238. Published online 2021 Jun 2. doi: 10.4274/jcrpe.galenos.2020.2019.0216

PMCID:: PMC8186340

Abstract Article PDF–736K

Select item 79548694.

Characterization of human adrenal cytochrome P450 11B2 products of progesterone and androstenedione oxidation

Sarah M. Glass, Michael J. Reddish, Stella A. Child, Clayton J. Wilkey, Donald F. Stec, F. Peter Guengerich

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2021 Apr; 208: 105787. Published online 2020 Nov 12. doi: 10.1016/j.jsbmb.2020.105787

PMCID:: PMC7954869

Abstract Article PDF–1.4M

Select item 77102335.

Correlation between CYP11B2 polymorphism and the risk of preeclampsia

Yan Wang, Minhua Zhou, Xun Deng, Yanjiao Ma, Deqi Jiang

Medicine (Baltimore) 2020 Nov 25; 99(48): e23322. Published online 2020 Nov 25. doi: 10.1097/MD.0000000000023322

PMCID:: PMC7710233

Abstract Article PDF–396K

Select item 75030176.

Association of −344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension

Lili Wang, Zhi Zhang, Dongxia Liu, Kexin Yuan, Guohua Zhu, Xiaoyong Qi

J Int Med Res. 2020 Sep; 48(9): 0300060520949409. Published online 2020 Sep 16. doi: 10.1177/0300060520949409

PMCID:: PMC7503017

Abstract Article PDF–226K

Select item 74271327.

Lack of association between CYP11B2 -344T/C polymorphism and transient ischemic attack in a Chinese population

Jia Fan, Yaoliang Shen, Bo Chen, Chunyang Xu, Hongwei Ye, Jian Wang, Wenjun Zhou, Yuefeng Sheng, Feng Xu, Peng Yang

J Int Med Res. 2020 Aug; 48(8): 0300060520947916. Published online 2020 Aug 13. doi: 10.1177/0300060520947916

PMCID:: PMC7427132

Abstract Article PDF–574K

Select item 72997438.

IMMUNOHISTOCHEMISTRY OF THE HUMAN ADRENAL CYP11B2 IN NORMAL INDIVIDUALS AND IN PATIENTS WITH PRIMARY ALDOSTERONISM

Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Koshiro Nishimoto

Horm Metab Res. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Horm Metab Res. 2020 Jun; 52(6): 421–426. Published online 2020 Apr 14. doi: 10.1055/a-1139-2079

PMCID:: PMC7299743

Abstract Article PDF–518K

Select item 67867719.

Expression of aldosterone synthase CYP11B2 was inversely correlated with longevity

Taiki Hayashi, Zhen Zhang, Ghaith Al-Eyd, Atsushi Sasaki, Masanori Yasuda, Masafumi Oyama, Celso E. Gomez-Sanchez, Hirotaka Asakura, Tsugio Seki, Kuniaki Mukai, Koshiro Nishimoto

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2019 Jul; 191: 105361. Published online 2019 Apr 8. doi: 10.1016/j.jsbmb.2019.04.010

PMCID:: PMC6786771

Abstract Article PDF–1.8M

Select item 672195110.

Human cytochrome P450 11B2 produces aldosterone by a processive mechanism due to the lactol form of the intermediate 18-hydroxycorticosterone

Michael J. Reddish, F. Peter Guengerich

J Biol Chem. 2019 Aug 30; 294(35): 12975–12991. Published online 2019 Jul 11. doi: 10.1074/jbc.RA119.009830

PMCID:: PMC6721951

Abstract Article PDF–2.1M

Select item 584387611.

Association of aldosterone synthase (CYP11B2) -344 T/C polymorphism with diabetic nephropathy: A meta-analysis

Haiyan Xu, Xu Wang, Mingming Liu, Xin Shao, Xueyuan He

J Renin Angiotensin Aldosterone Syst. 2016 Jan-Mar; 17(1): 1470320316633896. Published online 2016 Mar 8. doi: 10.1177/1470320316633896

PMCID:: PMC5843876

Abstract Article PDF–525K

Select item 562630012.

A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension

Hao Zhang, Xueyan Li, Li Zhou, Keyong Zhang, Qi Zhang, Jingping Li, Ningning Wang, Ming Jin, Nan Wu, Mingyu Cong, Changchun Qiu

Medicine (Baltimore) 2017 Sep; 96(39): e8150. Published online 2017 Sep 29. doi: 10.1097/MD.0000000000008150

PMCID:: PMC5626300

Abstract Article PDF–314K

Select item 556880613.

Age-Related Autonomous Aldosteronism

Kazutaka Nanba, Anand Vaidya, Gordon H. Williams, Isabel Zheng, Tobias Else, William E. Rainey

Circulation. Author manuscript; available in PMC 2018 Jul 25.

Published in final edited form as: Circulation. 2017 Jul 25; 136(4): 347–355. Published online 2017 May 31. doi: 10.1161/CIRCULATIONAHA.117.028201

PMCID:: PMC5568806

Abstract Article PDF–1.0M

Select item 547892314.

Different Expression of 11β-Hydroxylase and Aldosterone Synthase Between Aldosterone-Producing Microadenomas and Macroadenomas

Yoshikiyo Ono, Yasuhiro Nakamura, Takashi Maekawa, Saulo J.A. Felizola, Ryo Morimoto, Yoshitsugu Iwakura, Masataka Kudo, Kazumasa Seiji, Kei Takase, Yoichi Arai, Celso E. Gomez-Sanchez, Sadayoshi Ito, Hironobu Sasano, Fumitoshi Satoh

Hypertension. Author manuscript; available in PMC 2017 Jun 21.

Published in final edited form as: Hypertension. 2014 Aug; 64(2): 438–444. Published online 2014 May 19. doi: 10.1161/HYPERTENSIONAHA.113.02944

PMCID:: PMC5478923

Abstract Article PDF–1.1M

Select item 515926115.

Hypo-methylation of CYP11B2 in aldosterone-producing adenoma

Yoko Yoshii, Kenji Oki, Celso E Gomez-Sanchez, Haruya Ohno, Kiyotaka Itcho, Kazuhiro Kobuke, Masayasu Yoneda

Hypertension. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Hypertension. 2016 Dec; 68(6): 1432–1437. Published online 2016 Oct 17. doi: 10.1161/HYPERTENSIONAHA.116.08313

PMCID:: PMC5159261

Abstract Article PDF–785K

Select item 512394616.

DISORDERED ZONAL AND CELLULAR CYP11B2 ENZYME EXPRESSION IN FAMILIAL HYPERALDOSTERONISM TYPE 3

Celso E. Gomez-Sanchez, Xin Qi, Elise P. Gomez-Sanchez, Hironobu Sasano, Martin O. Bohlen, Max Wisgerhof

Mol Cell Endocrinol. Author manuscript; available in PMC 2018 Jan 5.

Published in final edited form as: Mol Cell Endocrinol. 2017 Jan 5; 439: 74–80. Published online 2016 Oct 25. doi: 10.1016/j.mce.2016.10.025

PMCID:: PMC5123946

Abstract Article PDF–1.8M

Select item 506599817.

Discovery of Potential Inhibitors of Aldosterone Synthase from Chinese Herbs Using Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation Studies

Ganggang Luo, Fang Lu, Liansheng Qiao, Xi Chen, Gongyu Li, Yanling Zhang

Biomed Res Int. 2016; 2016: 4182595. Published online 2016 Oct 3. doi: 10.1155/2016/4182595

PMCID:: PMC5065998

Abstract Article PDF–2.0M

Select item 480317118.

Molecular Heterogeneity in Aldosterone-Producing Adenomas

Kazutaka Nanba, Andrew X. Chen, Kei Omata, Michelle Vinco, Thomas J. Giordano, Tobias Else, Gary D. Hammer, Scott A. Tomlins, William E. Rainey

J Clin Endocrinol Metab. 2016 Mar; 101(3): 999–1007. Published online 2016 Jan 14. doi: 10.1210/jc.2015-3239

PMCID:: PMC4803171

Abstract Article

Select item 412743819.

Genetic variant of the renin-angiotensin system and prevalence of type 2 diabetes mellitus: a modest but significant effect of aldosterone synthase

Mai Ichikawa, Tadashi Konoshita, Takahiro Nakaya, Katsushi Yamamoto, Mika Yamada, Satsuki Sato, Michiko Imagawa, Yasukazu Makino, Miki Fujii, Yasuo Zenimaru, Kenichiro Arakawa, Jinya Suzuki, Tamotsu Ishizuka, Hiroyuki Nakamura

Acta Diabetol. 2014; 51(4): 595–599. Published online 2014 Feb 19. doi: 10.1007/s00592-014-0561-7

PMCID:: PMC4127438

Abstract Article PDF–176K

Select item 412521620.

Computational Analysis of Functional Single Nucleotide Polymorphisms Associated with the CYP11B2 Gene

Minyue Jia, Boyun Yang, Zhongyi Li, Huiling Shen, Xiaoxiao Song, Wei Gu

PLoS One. 2014; 9(8): e104311. Published online 2014 Aug 7. doi: 10.1371/journal.pone.0104311

PMCID:: PMC4125216

Abstract Article PDF–3.3M

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