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Select item 110457451.

NMR characterization of RNA binding property of the DEAD-box RNA helicase DDX3X and its implications for helicase activity

Yuki Toyama, Ichio Shimada

Nat Commun. 2024; 15: 3303. Published online 2024 Apr 25. doi: 10.1038/s41467-024-47659-w

PMCID:: PMC11045745

Abstract Article PDF–2.6M

Select item 110285712.

DEAD/H (Asp–Glu–Ala–Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells

Jun Koshio, Hiroshi Kagamu, Koichiro Nozaki, Yu Saida, Tomohiro Tanaka, Satoshi Shoji, Natsue Igarashi, Satoru Miura, Masaaki Okajima, Satoshi Watanabe, Hirohisa Yoshizawa, Ichiei Narita

Cancer Immunol Immunother. 2013 Oct; 62(10): 1619–1628. Published online 2013 Aug 22. doi: 10.1007/s00262-013-1467-x

PMCID:: PMC11028571

Abstract Article PDF–1.0M

Select item 102976143.

Perturbation Analysis of a Prognostic DDX3X-Mediated Gene Expression Signature Identifies the Antimetastatic Potential of Chaetocin in Hepatocellular Carcinoma

Tsung-Chieh Lin

Cells. 2023 Jun; 12(12): 1628. Published online 2023 Jun 14. doi: 10.3390/cells12121628

PMCID:: PMC10297614

Abstract Article PDF–10M

Select item 92744934.

DDX3 acts as a tumor suppressor in colorectal cancer as loss of DDX3 in advanced cancer promotes tumor progression by activating the MAPK pathway

Lin Shen, Jing Zhang, Meng Xu, Ying Zheng, Mo Wang, Suzhen Yang, Bin Qin, Shunle Li, Lei Dong, Fei Dai

Int J Biol Sci. 2022; 18(10): 3918–3933. Published online 2022 Jun 6. doi: 10.7150/ijbs.73491

PMCID:: PMC9274493

Abstract Article PDF–3.9M

Select item 89721365.

The translational landscape as regulated by the RNA helicase DDX3

Joon Tae Park, Sekyung Oh

BMB Rep. 2022 Mar 31; 55(3): 125–135. Published online 2022 Mar 31. doi: 10.5483/BMBRep.2022.55.3.188

PMCID:: PMC8972136

Abstract Article PDF–5.4M

Select item 89138476.

The RNA helicase DDX3 promotes IFNB transcription via enhancing IRF-3/p300 holocomplex binding to the IFNB promoter

Wilaiporn Saikruang, Lena Ang Yan Ping, Hiroto Abe, Dacquin M. Kasumba, Hiroki Kato, Takashi Fujita

Sci Rep. 2022; 12: 3967. Published online 2022 Mar 10. doi: 10.1038/s41598-022-07876-z

PMCID:: PMC8913847

Abstract Article PDF–2.0M

Select item 88470067.

DDX3X mRNA Expression in T Cells Is Associated with the Severity and Mortality of Septic Patients

Yukun Liu, Yongsheng Zhang, Qinxin Liu, Weiming Xie, Xiang Wang, Fan Yang, Wei Gao, Xiangjun Bai, Zhanfei Li, Yuchang Wang

Dis Markers. 2022; 2022: 5176915. Published online 2022 Feb 8. doi: 10.1155/2022/5176915

PMCID:: PMC8847006

Abstract Article PDF–544K

Select item 88327458.

Multi-omic analysis reveals significantly mutated genes and DDX3X as a sex-specific tumor suppressor in cutaneous melanoma

Rached Alkallas, Mathieu Lajoie, Dan Moldoveanu, Karen Vo Hoang, Philippe Lefrançois, Marine Lingrand, Mozhdeh Ahanfeshar-Adams, Kevin Watters, Alan Spatz, Jonathan H. Zippin, Hamed S. Najafabadi, Ian R. Watson

Nat Cancer. Author manuscript; available in PMC 2022 Feb 11.

Published in final edited form as: Nat Cancer. 2020 Jun; 1(6): 635–652. Published online 2020 Jun 22. doi: 10.1038/s43018-020-0077-8

PMCID:: PMC8832745

Abstract Article PDF–9.2M

Select item 85979819.

Targeting DDX3X triggers anti-tumor immunity via a dsRNA-mediated tumor-intrinsic type I interferon response

Hyeongjwa Choi, Juntae Kwon, Min Soon Cho, Yifan Sun, Xiaofeng Zheng, Jing Wang, Kerrie B. Bouker, John L. Casey, Michael B. Atkins, Jeffrey Toretsky, Cecil Han

Cancer Res. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Cancer Res. 2021 Jul 1; 81(13): 3607–3620. Published online 2021 May 3. doi: 10.1158/0008-5472.CAN-20-3790

PMCID:: PMC8597981

Abstract Article PDF–2.6M

Select item 854456910.

RNA helicase, DDX3X, is actively recruited to sites of DNA damage in live cells

Michael J. Cargill, Alicia Morales, Shashidhar Ravishankar, Edus H. Warren

DNA Repair (Amst) Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: DNA Repair (Amst). 2021 Jul; 103: 103137. Published online 2021 May 18. doi: 10.1016/j.dnarep.2021.103137

PMCID:: PMC8544569

Abstract Article PDF–973K

Select item 852025611.

DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes

Atish Kizhakeyil, Nurmahirah Binte Mohammed Zaini, Zhi Sheng Poh, Brandon Han Siang Wong, Xinpeng Loh, Aik Seng Ng, Zun Siong Low, Praseetha Prasannan, Chun Gong, Michelle Guet Khim Tan, Chandramouli Nagarajan, Dachuan Huang, Pang Wan Lu, Jing Quan Lim, Sharon Barrans, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, George Follows, Daniel J. Hodson, Ming Qing Du, Yeow Tee Goh, Suat Hoon Tan, Nicholas Francis Grigoropoulos, Navin Kumar Verma

Mol Cancer. 2021; 20: 134. Published online 2021 Oct 16. doi: 10.1186/s12943-021-01437-0

PMCID:: PMC8520256

Article PDF–3.7M

Select item 851678112.

Cytoplasmic DDX3 as prognosticator in male breast cancer

Carmen C. van der Pol, Cathy B. Moelans, Quirine F. Manson, Marilot C. T. Batenburg, Elsken van der Wall, Inne Borel Rinkes, Lenny Verkooijen, Venu Raman, Paul J. van Diest

Virchows Arch. 2021; 479(4): 647–655. Published online 2021 May 11. doi: 10.1007/s00428-021-03107-4

PMCID:: PMC8516781

Abstract Article PDF–1017K

Select item 813683113.

DDX3 depletion represses translation of mRNAs with complex 5′ UTRs

Lorenzo Calviello, Srivats Venkataramanan, Karol J Rogowski, Emanuel Wyler, Kevin Wilkins, Malvika Tejura, Bao Thai, Jacek Krol, Witold Filipowicz, Markus Landthaler, Stephen N Floor

Nucleic Acids Res. 2021 May 21; 49(9): 5336–5350. Published online 2021 Apr 27. doi: 10.1093/nar/gkab287

PMCID:: PMC8136831

Abstract Article PDF–3.1M

Select item 812724814.

Prospective and detailed behavioral phenotyping in DDX3X syndrome

Lara Tang, Tess Levy, Sylvia Guillory, Danielle Halpern, Jessica Zweifach, Ivy Giserman-Kiss, Jennifer H. Foss-Feig, Yitzchak Frank, Reymundo Lozano, Puneet Belani, Christina Layton, Bonnie Lerman, Emanuel Frowner, Michael S. Breen, Silvia De Rubeis, Ana Kostic, Alexander Kolevzon, Joseph D. Buxbaum, Paige M. Siper, Dorothy E. Grice

Mol Autism. 2021; 12: 36. Published online 2021 May 16. doi: 10.1186/s13229-021-00431-z

PMCID:: PMC8127248

Abstract Article PDF–1.3M

Select item 808766815.

Selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir

Shringar Rao, Cynthia Lungu, Raquel Crespo, Thijs H. Steijaert, Alicja Gorska, Robert-Jan Palstra, Henrieke A. B. Prins, Wilfred van Ijcken, Yvonne M. Mueller, Jeroen J. A. van Kampen, Annelies Verbon, Peter D. Katsikis, Charles A. B. Boucher, Casper Rokx, Rob A. Gruters, Tokameh Mahmoudi

Nat Commun. 2021; 12: 2475. Published online 2021 Apr 30. doi: 10.1038/s41467-021-22608-z

PMCID:: PMC8087668

Abstract Article PDF–3.1M

Select item 790376616.

DDX3X: structure, physiologic functions and cancer

Jie Mo, Huifang Liang, Chen Su, Pengcheng Li, Jin Chen, Bixiang Zhang

Mol Cancer. 2021; 20: 38. Published online 2021 Feb 24. doi: 10.1186/s12943-021-01325-7

PMCID:: PMC7903766

Abstract Article PDF–2.5M

Select item 767243717.

Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

Valentina Riva, Anna Garbelli, Federica Casiraghi, Francesca Arena, Claudia Immacolata Trivisani, Assunta Gagliardi, Luca Bini, Martina Schroeder, Antonio Maffia, Simone Sabbioneda, Giovanni Maga

Nucleic Acids Res. 2020 Nov 18; 48(20): 11551–11565. Published online 2020 Nov 2. doi: 10.1093/nar/gkaa948

PMCID:: PMC7672437

Abstract Article PDF–3.2M

Select item 711193018.

Cellular DDX3 regulates Japanese encephalitis virus replication by interacting with viral un-translated regions

Chen Li, Ling-ling Ge, Peng-peng Li, Yue Wang, Juan-juan Dai, Ming-xia Sun, Li Huang, Zhi-qiang Shen, Xiao-chun Hu, Hassan Ishag, Xiang Mao

Virology. 2014 Jan 20; 449: 70–81. Published online 2013 Nov 26. doi: 10.1016/j.virol.2013.11.008

PMCID:: PMC7111930

Abstract Article PDF–2.8M

Select item 677761819.

Three de novo DDX3X variants associated with distinctive brain developmental abnormalities and brain tumor in intellectually disabled females

Marcello Scala, Annalaura Torella, Mariasavina Severino, Giovanni Morana, Raffaele Castello, Andrea Accogli, Antonio Verrico, Maria Stella Vari, Gerarda Cappuccio, Michele Pinelli, Giuseppina Vitiello, Gaetano Terrone, Alessandra D’Amico, TUDP consortium, Vincenzo Nigro, Valeria Capra

Eur J Hum Genet. 2019 Aug; 27(8): 1254–1259. Published online 2019 Apr 1. doi: 10.1038/s41431-019-0392-7

PMCID:: PMC6777618

Abstract Article PDF–732K

Select item 662604320.

The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X

He Song, Xinhua Ji

Nat Commun. 2019; 10: 3085. Published online 2019 Jul 12. doi: 10.1038/s41467-019-11083-2

PMCID:: PMC6626043

Abstract Article PDF–2.3M

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PMC Links for Gene (Select 1654) (350)
PMC
PREDICTED: Homo sapiens RAB2B, member RAS oncogene family (RAB2B), transcript va...
PREDICTED: Homo sapiens RAB2B, member RAS oncogene family (RAB2B), transcript variant X2, mRNA
gi|2217298642|ref|XM_017021712.2|

Nucleotide
ATP-dependent RNA helicase DDX3X isoform 2 [Homo sapiens]
ATP-dependent RNA helicase DDX3X isoform 2 [Homo sapiens]
gi|301171467|ref|NP_001180345.1|

Protein
Microbe sample from Klebsiella pneumoniae
Microbe sample from Klebsiella pneumoniae

biosample
BioSample links for Nucleotide (Select 1566133641) (1)
BioSample

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