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Select item 107718111.

Dual transgene amelioration of Lama2-null muscular dystrophy

Karen K. McKee, Peter D. Yurchenco

Matrix Biol. Author manuscript; available in PMC 2024 Jan 7.

Published in final edited form as: Matrix Biol. 2023 Apr; 118: 1–15. Published online 2023 Mar 5. doi: 10.1016/j.matbio.2023.03.001

PMCID:: PMC10771811

Abstract Article PDF–4.2M

Select item 75267902.

Laminin-111 protein therapy after disease onset slows muscle disease in a mouse model of laminin-α2 related congenital muscular dystrophy

Pamela Barraza-Flores, Katherine E Bukovec, Marisela Dagda, Brandon W Conner, Ariany Oliveira-Santos, Robert W Grange, Dean J Burkin

Hum Mol Genet. 2020 Aug 3; 29(13): 2162–2170. Published online 2020 May 29. doi: 10.1093/hmg/ddaa104

PMCID:: PMC7526790

Abstract Article PDF–1.1M

Select item 72715473.

Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD

Pamela Barraza-Flores, Hailey J. Hermann, Christina R. Bates, Tyler G. Allen, Timothy T. Grunert, Dean J. Burkin

Skelet Muscle. 2020; 10: 18. Published online 2020 Jun 4. doi: 10.1186/s13395-020-00235-4

PMCID:: PMC7271547

Abstract Article PDF–4.7M

Select item 67780734.

Early skeletal muscle pathology and disease progress in the dy^3K/dy^3K mouse model of congenital muscular dystrophy with laminin α2 chain-deficiency

Kinga I. Gawlik, Zandra Körner, Bruno M. Oliveira, Madeleine Durbeej

Sci Rep. 2019; 9: 14324. Published online 2019 Oct 4. doi: 10.1038/s41598-019-50550-0

PMCID:: PMC6778073

Abstract Article PDF–9.4M

Select item 66180385.

Current understanding and treatment of cardiac and skeletal muscle pathology in laminin-α2 chain-deficient congenital muscular dystrophy

Quynh Nguyen, Kenji Rowel Q Lim, Toshifumi Yokota

Appl Clin Genet. 2019; 12: 113–130. Published online 2019 Jul 3. doi: 10.2147/TACG.S187481

PMCID:: PMC6618038

Abstract Article PDF–1.1M

Select item 65733026.

Clustering of Voltage-Sensitive Sodium Channels on Axons Is Independent of Direct Schwann Cell Contact in the Dystrophic Mouse

Thomas J. Deerinck, S. Rock Levinson, G. Vann Bennett, Mark H. Ellisman

J Neurosci. 1997 Jul 1; 17(13): 5080–5088. doi: 10.1523/JNEUROSCI.17-13-05080.1997

PMCID:: PMC6573302

Abstract Article PDF–1.4M

Select item 62149877.

Effects of metformin on congenital muscular dystrophy type 1A disease progression in mice: a gender impact study

Cibely C. Fontes-Oliveira, Bernardo M. Soares Oliveira, Zandra Körner, Vahid M. Harandi, Madeleine Durbeej

Sci Rep. 2018; 8: 16302. Published online 2018 Nov 2. doi: 10.1038/s41598-018-34362-2

PMCID:: PMC6214987

Abstract Article PDF–3.8M

Select item 59534808.

Natural disease history of the dy^2J mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy

S. Pasteuning-Vuhman, K. Putker, C. L. Tanganyika-de Winter, J. W. Boertje-van der Meulen, L. van Vliet, M. Overzier, J. J. Plomp, A. Aartsma-Rus, M. van Putten

PLoS One. 2018; 13(5): e0197388. Published online 2018 May 15. doi: 10.1371/journal.pone.0197388

PMCID:: PMC5953480

Abstract Article PDF–7.0M

Select item 56792259.

Laminin regulates postnatal oligodendrocyte production by promoting oligodendrocyte progenitor survival in the subventricular zone

Jenne Relucio, Michael J. Menezes, Yuko Miyagoe-Suzuki, Shin’ichi Takeda, Holly Colognato

Glia. Author manuscript; available in PMC 2017 Nov 9.

Published in final edited form as: Glia. 2012 Oct; 60(10): 1451–1467. Published online 2012 Jun 17. doi: 10.1002/glia.22365

PMCID:: PMC5679225

Abstract Article PDF–2.4M

Select item 533072310.

Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype

Karen K. McKee, Stephanie C. Crosson, Sarina Meinen, Judith R. Reinhard, Markus A. Rüegg, Peter D. Yurchenco

J Clin Invest. 2017 Mar 1; 127(3): 1075–1089. Published online 2017 Feb 20. doi: 10.1172/JCI90854

PMCID:: PMC5330723

Abstract Article PDF–4.3M

Select item 470123011.

Bortezomib Does Not Reduce Muscular Dystrophy in the dy^2J/dy^2J Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy

Zandra Körner, Madeleine Durbeej

PLoS One. 2016; 11(1): e0146471. Published online 2016 Jan 5. doi: 10.1371/journal.pone.0146471

PMCID:: PMC4701230

Abstract Article PDF–5.4M

Select item 408026112.

Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

Johan Holmberg, Azra Alajbegovic, Kinga Izabela Gawlik, Linda Elowsson, Madeleine Durbeej

Front Aging Neurosci. 2014; 6: 155. Published online 2014 Jul 3. doi: 10.3389/fnagi.2014.00155

PMCID:: PMC4080261

Abstract Article PDF–4.5M

Select item 386935613.

Laminin-111 improves muscle repair in a mouse model of merosin-deficient congenital muscular dystrophy

Pam M. Van Ry, Priscilla Minogue, Bradley L. Hodges, Dean J. Burkin

Hum Mol Genet. 2014 Jan 15; 23(2): 383–396. Published online 2013 Sep 5. doi: 10.1093/hmg/ddt428

PMCID:: PMC3869356

Abstract Article PDF–1.3M

Select item 367514414.

Omigapil Treatment Decreases Fibrosis and Improves Respiratory Rate in dy^2J Mouse Model of Congenital Muscular Dystrophy

Qing Yu, Arpana Sali, Jack Van der Meulen, Brittany K. Creeden, Heather Gordish-Dressman, Anne Rutkowski, Sree Rayavarapu, Kitipong Uaesoontrachoon, Tony Huynh, Kanneboyina Nagaraju, Christopher F. Spurney

PLoS One. 2013; 8(6): e65468. Published online 2013 Jun 6. doi: 10.1371/journal.pone.0065468

PMCID:: PMC3675144

Abstract Article PDF–489K

Select item 359838015.

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A)

Sarina Meinen, Shuo Lin, Markus A Ruegg

Skelet Muscle. 2012; 2: 18. Published online 2012 Sep 3. doi: 10.1186/2044-5040-2-18

PMCID:: PMC3598380

Abstract Article PDF–2.4M

Select item 341476116.

Inflammation modulates expression of laminin in the central nervous system following ischemic injury

Kyungmin Ji, Stella E Tsirka

J Neuroinflammation. 2012; 9: 159. Published online 2012 Jul 3. doi: 10.1186/1742-2094-9-159

PMCID:: PMC3414761

Abstract Article PDF–2.8M

Select item 337708817.

Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice

Sarina Meinen, Shuo Lin, Raphael Thurnherr, Michael Erb, Thomas Meier, Markus A Rüegg

EMBO Mol Med. 2011 Aug; 3(8): 465–479. doi: 10.1002/emmm.201100151

PMCID:: PMC3377088

Abstract Article PDF–1.7M

Select item 334989918.

Laminin-111 Protein Therapy Reduces Muscle Pathology and Improves Viability of a Mouse Model of Merosin-Deficient Congenital Muscular Dystrophy

Jachinta E. Rooney, Jolie R. Knapp, Bradley L. Hodges, Ryan D. Wuebbles, Dean J. Burkin

Am J Pathol. 2012 Apr; 180(4): 1593–1602. doi: 10.1016/j.ajpath.2011.12.019

PMCID:: PMC3349899

Abstract Article PDF–1.7M

Select item 311000419.

Peripheral nerve pathology, including aberrant Schwann cell differentiation, is ameliorated by doxycycline in a laminin-α2-deficient mouse model of congenital muscular dystrophy

Sachiko Homma, Mary Lou Beermann, Jeffrey Boone Miller

Hum Mol Genet. 2011 Jul 1; 20(13): 2662–2672. Published online 2011 Apr 19. doi: 10.1093/hmg/ddr168

PMCID:: PMC3110004

Abstract Article PDF–462K

Select item 306256520.

The Ras Antagonist, Farnesylthiosalicylic Acid (FTS), Decreases Fibrosis and Improves Muscle Strength in dy^2J/dy^2J Mouse Model of Muscular Dystrophy

Yoram Nevo, Shlomit Aga-Mizrachi, Edva Elmakayes, Nurit Yanay, Keren Ettinger, Moran Elbaz, Zivia Brunschwig, Oshrat Dadush, Galit Elad-Sfadia, Roni Haklai, Yoel Kloog, Joab Chapman, Shimon Reif

PLoS One. 2011; 6(3): e18049. Published online 2011 Mar 22. doi: 10.1371/journal.pone.0018049

PMCID:: PMC3062565

Abstract Article PDF–402K

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PMC Links for Gene (Select 16773) (139)
PMC
laminin subunit alpha-2 isoform X4 [Mus musculus]
laminin subunit alpha-2 isoform X4 [Mus musculus]
gi|568965053|ref|XP_006512629.1|

Protein
Mus musculus mitogen regulated protein 4 precursor (Mrpplf4) mRNA, complete cds
Mus musculus mitogen regulated protein 4 precursor (Mrpplf4) mRNA, complete cds
gi|8071617|gb|AF128884.1|

Nucleotide
Mus musculus prolactin family 2, subfamily c, member 4, mRNA (cDNA clone MGC:604...
Mus musculus prolactin family 2, subfamily c, member 4, mRNA (cDNA clone MGC:60424 IMAGE:30053850), complete cds
gi|37573964|gb|BC058816.1|

Nucleotide

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