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Items: 1 to 20 of 131

1.
Association of solute carrier family 30 A8 zinc transporter gene variations with gestational diabetes mellitus risk in a Chinese population
Qiaoli Zeng, Bing Tan, Fengqiong Han, Xiujuan Huang, Jinzhi Huang, Yue Wei, Runmin Guo
Front Endocrinol (Lausanne) 2023; 14: 1159714. Published online 2023 May 31. doi: 10.3389/fendo.2023.1159714
PMCID:
PMC10266221
AbstractArticlePDF–1.3M
2.
ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition
Lina Sui, Qian Du, Anthony Romer, Qi Su, Pauline L. Chabosseau, Yurong Xin, Jinrang Kim, Sandra Kleiner, Guy A. Rutter, Dieter Egli
Cells. 2023 Mar; 12(6): 903. Published online 2023 Mar 15. doi: 10.3390/cells12060903
PMCID:
PMC10047077
AbstractArticlePDF–3.6M
3.
Autoantibodies to Zinc Transporter 8 and SLC30A8 Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa
Raouia Fakhfakh, Sana Kmiha, Safa Tahri, Sawsan Feki, Ferjeni Zouidi, Olfa Abida, Mongia Hachicha, Thouraya Kammoun, Hatem Masmoudi
J Diabetes Res. 2022; 2022: 2539871. Published online 2022 May 23. doi: 10.1155/2022/2539871
PMCID:
PMC9152414
AbstractArticlePDF–527K
4.
Insights into the Dynamics of the Human Zinc Transporter ZnT8 by MD Simulations
Davide Sala, Andrea Giachetti, Antonio Rosato
J Chem Inf Model. 2021 Feb 22; 61(2): 901–912. Published online 2021 Jan 29. doi: 10.1021/acs.jcim.0c01139
PMCID:
PMC8023586
AbstractArticlePDF–7.8M
5.
Probing the Structure and Function of the Cytosolic Domain of the Human Zinc Transporter ZnT8 with Nickel(II) Ions
Maria Carmen Catapano, Douglas S. Parsons, Radosław Kotuniak, Přemysl Mladěnka, Wojciech Bal, Wolfgang Maret
Int J Mol Sci. 2021 Mar; 22(6): 2940. Published online 2021 Mar 14. doi: 10.3390/ijms22062940
PMCID:
PMC8000985
AbstractArticlePDF–12M
6.
Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations
Jing Xue, Tian Xie, Weizhong Zeng, Youxing Jiang, Xiao-chen Bai
eLife. 2020; 9: e58823. Published online 2020 Jul 29. doi: 10.7554/eLife.58823
PMCID:
PMC7428307
AbstractArticlePDF–4.1M
7.
C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W)
Raheem Ullah, Aamir Shehzad, Majid Ali Shah, Matteo De March, Fouzia Ismat, Mazhar Iqbal, Silvia Onesti, Moazur Rahman, Michael J. McPherson
Int J Mol Sci. 2020 Feb; 21(3): 926. Published online 2020 Jan 31. doi: 10.3390/ijms21030926
PMCID:
PMC7037036
AbstractArticlePDF–2.3M
8.
Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
Chengfeng Merriman, Dax Fu
J Biol Chem. 2019 Nov 8; 294(45): 16992–17006. Published online 2019 Oct 7. doi: 10.1074/jbc.RA119.010937
PMCID:
PMC6851310
AbstractArticlePDF–3.2M
9.
What has zinc transporter 8 autoimmunity taught us about type 1 diabetes?
Claire L. Williams, Anna E. Long
Diabetologia. 2019; 62(11): 1969–1976. Published online 2019 Aug 23. doi: 10.1007/s00125-019-04975-x
PMCID:
PMC6805822
AbstractArticlePDF–748K
10.
SLC30A8 Gene rs13266634 C/T Polymorphism in Children with Type 1 Diabetes in Tamil Nadu, India
Ramasamy Thirunavukkarasu, Arthur Joseph Asirvatham, Ayyappan Chitra, Mariakuttikan Jayalakshmi
J Clin Res Pediatr Endocrinol. 2019 Mar; 11(1): 55–60. Published online 2019 Feb 20. doi: 10.4274/jcrpe.galenos.2018.2018.0195
PMCID:
PMC6398198
AbstractArticlePDF–443K
11.
Some dietary factors can modulate the effect of the zinc transporters 8 polymorphism on the risk of metabolic syndrome
Firoozeh Hosseini-Esfahani, Parvin Mirmiran, Gelareh Koochakpoor, Maryam S. Daneshpour, Kamran Guity, Fereidoun Azizi
Sci Rep. 2017; 7: 1649. Published online 2017 May 10. doi: 10.1038/s41598-017-01762-9
PMCID:
PMC5431973
AbstractArticlePDF–1.4M
12.
Exploring the Association Between Demographics, SLC30A8 Genotype, and Human Islet Content of Zinc, Cadmium, Copper, Iron, Manganese and Nickel
Winifred P. Wong, Norrina B. Allen, Matthew S. Meyers, Emma O. Link, Xiaomin Zhang, Keith W. MacRenaris, Malek El Muayed
Sci Rep. 2017; 7: 473. Published online 2017 Mar 28. doi: 10.1038/s41598-017-00394-3
PMCID:
PMC5428289
AbstractArticlePDF–1.3M
13.
Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans
Karla Fabiana Brasil Gomes, Cintia Semzezem, Rodolfo Batista, Rosa Tsuneshiro Fukui, Aritania Sousa Santos, Márcia Regina Correia, Maria Rita Passos-Bueno, Maria Elizabeth Rossi da Silva
Sci Rep. 2017; 7: 207. Published online 2017 Mar 16. doi: 10.1038/s41598-017-00307-4
PMCID:
PMC5428214
AbstractArticlePDF–1.3M
14.
hZnT8 (Slc30a8) Transgenic Mice That Overexpress the R325W Polymorph Have Reduced Islet Zn2+ and Proinsulin Levels, Increased Glucose Tolerance After a High-Fat Diet, and Altered Levels of Pancreatic Zinc Binding Proteins
Li Li, Shi Bai, Christian T. Sheline
Diabetes. 2017 Feb; 66(2): 551–559. Published online 2016 Nov 29. doi: 10.2337/db16-0323
Correction in:
Diabetes. 2019 Jul; 68(7): 1536.
PMCID:
PMC5248993
AbstractArticlePDF–1.4M
15.
Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes
Chengfeng Merriman, Qiong Huang, Guy A. Rutter, Dax Fu
J Biol Chem. 2016 Dec 30; 291(53): 26950–26957. Published online 2016 Nov 8. doi: 10.1074/jbc.M116.764605
PMCID:
PMC5207130
AbstractArticlePDF–1.3M
16.
Zinc-Associated Variant in SLC30A8 Gene Interacts With Gestational Weight Gain on Postpartum Glycemic Changes: A Longitudinal Study in Women With Prior Gestational Diabetes Mellitus
Tiange Wang, Huikun Liu, Leishen Wang, Tao Huang, Weiqin Li, Yan Zheng, Yoriko Heianza, Dianjianyi Sun, Junhong Leng, Shuang Zhang, Nan Li, Gang Hu, Lu Qi
Diabetes. 2016 Dec; 65(12): 3786–3793. Published online 2016 Sep 6. doi: 10.2337/db16-0730
PMCID:
PMC5127244
AbstractArticlePDF–866K
17.
Lack of Association between SLC30A8 Variants and Type 2 Diabetes in Mexican American Families
Hemant Kulkarni, Manju Mamtani, Juan Manuel Peralta, Vincent Diego, Thomas D. Dyer, Harald Goring, Laura Almasy, Michael C. Mahaney, Sarah Williams-Blangero, Ravindranath Duggirala, Joanne E. Curran, John Blangero
J Diabetes Res. 2016; 2016: 6463214. Published online 2016 Nov 8. doi: 10.1155/2016/6463214
PMCID:
PMC5118530
AbstractArticlePDF–668K
18.
News Feature: Genetic mutations you want
Sarah C. P. Williams
Proc Natl Acad Sci U S A. 2016 Mar 8; 113(10): 2554–2557. Published online 2016 Mar 8. doi: 10.1073/pnas.1601663113
Correction in:
Proc Natl Acad Sci U S A. 2016 Apr 5; 113(14): E2093.
PMCID:
PMC4791022
ArticlePDF–1.0M
19.
Association between SLC30A8 rs13266634 Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis
Liqing Cheng, Dongmei Zhang, Lina Zhou, Jie Zhao, Bing Chen
Med Sci Monit. 2015; 21: 2178–2189. Published online 2015 Jul 27. doi: 10.12659/MSM.894052
PMCID:
PMC4527121
AbstractArticlePDF–923K
20.
Effect of zinc supplementation on insulin secretion: interaction between zinc and SLC30A8 genotype in Old Order Amish
Nisa M. Maruthur, Jeanne M. Clark, Mao Fu, W. H. Linda Kao, Alan R. Shuldiner
Diabetologia. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Diabetologia. 2015 Feb; 58(2): 295–303. Published online 2014 Oct 28. doi: 10.1007/s00125-014-3419-1
PMCID:
PMC4505931
AbstractArticlePDF–518K

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