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Select item 90676511.

Expression of toll like receptor 8 (TLR8) in specific groups of mouse hippocampal interneurons

Lennart Seizer, Sadegh Rahimi, Sandra Santos-Sierra, Meinrad Drexel

PLoS One. 2022; 17(5): e0267860. Published online 2022 May 4. doi: 10.1371/journal.pone.0267860

PMCID:: PMC9067651

Abstract Article PDF–3.6M

Select item 80558052.

TLR8 in the Trigeminal Ganglion Contributes to the Maintenance of Trigeminal Neuropathic Pain in Mice

Lin-Xia Zhao, Ming Jiang, Xue-Qiang Bai, De-Li Cao, Xiao-Bo Wu, Jing Zhang, Jian-Shuang Guo, Tong-Tong Chen, Juan Wang, Hao Wu, Yong-Jing Gao, Zhi-Jun Zhang

Neurosci Bull. 2021 Apr; 37(4): 550–562. Published online 2020 Dec 23. doi: 10.1007/s12264-020-00621-4

PMCID:: PMC8055805

Abstract Article PDF–2.4M

Select item 47328503.

Molecular cloning and functional characterization of murine toll-like receptor 8

TINGTING LI, XIAOBING HE, HUAIJIE JIA, GUOHUA CHEN, SHUANG ZENG, YONGXIANG FANG, QIWANG JIN, ZHIZHONG JING

Mol Med Rep. 2016 Feb; 13(2): 1119–1126. Published online 2015 Dec 10. doi: 10.3892/mmr.2015.4668

PMCID:: PMC4732850

Abstract Article PDF–2.3M

Select item 107806604.

Gender Control of Mouse Embryos by Activation of TLR7/8 on X Sperm via Ligands dsRNA-40 and dsRNA-DR

Yunfei Hou, Jingfeng Peng, Linjun Hong, Zhenfang Wu, Enqin Zheng, Zicong Li

Molecules. 2024 Jan; 29(1): 262. Published online 2024 Jan 4. doi: 10.3390/molecules29010262

PMCID:: PMC10780660

Abstract Article PDF–3.3M

Select item 77631625.

TLR7/8 in the Pathogenesis of Parkinson’s Disease

Michela Campolo, Alessia Filippone, Carmelo Biondo, Giuseppe Mancuso, Giovanna Casili, Marika Lanza, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti

Int J Mol Sci. 2020 Dec; 21(24): 9384. Published online 2020 Dec 9. doi: 10.3390/ijms21249384

PMCID:: PMC7763162

Abstract Article PDF–5.9M

Select item 70376046.

Development of RNA/DNA Hydrogel Targeting Toll-Like Receptor 7/8 for Sustained RNA Release and Potent Immune Activation

Fusae Komura, Kana Okuzumi, Yuki Takahashi, Yoshinobu Takakura, Makiya Nishikawa

Molecules. 2020 Feb; 25(3): 728. Published online 2020 Feb 7. doi: 10.3390/molecules25030728

PMCID:: PMC7037604

Abstract Article PDF–2.7M

Select item 67385757.

Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling

Noël Hanna Kazazian, Yawen Wang, Annie Roussel-Queval, Laetitia Marcadet, Lionel Chasson, Caroline Laprie, Benoit Desnues, Jonathan Charaix, Magali Irla, Lena Alexopoulou

Front Immunol. 2019; 10: 2015. Published online 2019 Sep 4. doi: 10.3389/fimmu.2019.02015

PMCID:: PMC6738575

Abstract Article PDF–3.5M

Select item 66919848.

Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm

Takashi Umehara, Natsumi Tsujita, Masayuki Shimada

PLoS Biol. 2019 Aug; 17(8): e3000398. Published online 2019 Aug 13. doi: 10.1371/journal.pbio.3000398

PMCID:: PMC6691984

Abstract Article PDF–3.1M

Select item 44053249.

Toll-like receptor 8 deletion accelerates autoimmunity in a mouse model of lupus through a Toll-like receptor 7-dependent mechanism

Ngoc Lan Tran, Céline Manzin-Lorenzi, Marie-Laure Santiago-Raber

Immunology. 2015 May; 145(1): 60–70. Published online 2015 Apr 14. doi: 10.1111/imm.12426

PMCID:: PMC4405324

Abstract Article PDF–483K

Select item 438712610.

The role of TLR8 signaling in Acute Myeloid Leukemia Differentiation

James J Ignatz-Hoover, Huaiyu Wang, Stephen A Moreton, Amit Chakrabarti, Mukesh K Agarwal, Kevin Sun, Kalpana Gupta, David N Wald

Leukemia. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Leukemia. 2015 Apr; 29(4): 918–926. Published online 2014 Oct 6. doi: 10.1038/leu.2014.293

PMCID:: PMC4387126

Abstract Article PDF–2.2M

Select item 425290111.

Overexpression of Toll-like receptor 8 correlates with the progression of podocyte injury in murine autoimmune glomerulonephritis

Junpei Kimura, Osamu Ichii, Kosuke Miyazono, Teppei Nakamura, Taro Horino, Saori Otsuka-Kanazawa, Yasuhiro Kon

Sci Rep. 2014; 4: 7290. Published online 2014 Dec 3. doi: 10.1038/srep07290

PMCID:: PMC4252901

Abstract Article PDF–892K

Select item 380440112.

Modulation of Murine Macrophage TLR7/8-Mediated Cytokine Expression by Mesenchymal Stem Cell-Conditioned Medium

Takahiro Asami, Makoto Ishii, Hideki Fujii, Ho Namkoong, Sadatomo Tasaka, Kenichi Matsushita, Ken Ishii, Kazuma Yagi, Hiroshi Fujiwara, Yohei Funatsu, Naoki Hasegawa, Tomoko Betsuyaku

Mediators Inflamm. 2013; 2013: 264260. Published online 2013 Sep 28. doi: 10.1155/2013/264260

PMCID:: PMC3804401

Abstract Article PDF–1.5M

Select item 314106413.

Poly-Thymidine Oligonucleotides Mediate Activation of Murine Glial Cells Primarily Through TLR7, Not TLR8

Min Du, Niranjan B. Butchi, Tyson Woods, Karin E. Peterson

PLoS One. 2011; 6(7): e22454. Published online 2011 Jul 21. doi: 10.1371/journal.pone.0022454

PMCID:: PMC3141064

Abstract Article PDF–824K

Select item 308376214.

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

Kathrin Kastenmüller, Ulrike Wille-Reece, Ross W.B. Lindsay, Lauren R. Trager, Patricia A. Darrah, Barbara J. Flynn, Maria R. Becker, Mark C. Udey, Björn E. Clausen, Botond Z. Igyarto, Daniel H. Kaplan, Wolfgang Kastenmüller, Ronald N. Germain, Robert A. Seder

J Clin Invest. 2011 May 2; 121(5): 1782–1796. Published online 2011 Apr 11. doi: 10.1172/JCI45416

PMCID:: PMC3083762

Abstract Article PDF–1.5M

Select item 294722315.

TLR8 deficiency leads to autoimmunity in mice

Olivier Demaria, Philippe P. Pagni, Stephanie Traub, Aude de Gassart, Nora Branzk, Andrew J. Murphy, David M. Valenzuela, George D. Yancopoulos, Richard A. Flavell, Lena Alexopoulou

J Clin Invest. 2010 Oct 1; 120(10): 3651–3662. Published online 2010 Sep 1. doi: 10.1172/JCI42081

PMCID:: PMC2947223

Abstract Article PDF–3.2M

Select item 206456216.

Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

Yinghua Ma, Jianxue Li, Isaac Chiu, Yawen Wang, Jacob A. Sloane, Jining Lü, Bela Kosaras, Richard L. Sidman, Joseph J. Volpe, Timothy Vartanian

J Cell Biol. 2006 Oct 23; 175(2): 209–215. doi: 10.1083/jcb.200606016

PMCID:: PMC2064562

Abstract Article PDF–3.3M

Select item 1035453617.

TLR7/8 stress response drives histiocytosis in SLC29A3 disorders

Takuma Shibata, Ryota Sato, Masato Taoka, Shin-Ichiroh Saitoh, Mayumi Komine, Kiyoshi Yamaguchi, Susumu Goyama, Yuji Motoi, Jiro Kitaura, Kumi Izawa, Yoshio Yamauchi, Yumiko Tsukamoto, Takeshi Ichinohe, Etsuko Fujita, Ryosuke Hiranuma, Ryutaro Fukui, Yoichi Furukawa, Toshio Kitamura, Toshiyuki Takai, Arinobu Tojo, Mamitaro Ohtsuki, Umeharu Ohto, Toshiyuki Shimizu, Manabu Ozawa, Nobuaki Yoshida, Toshiaki Isobe, Eicke Latz, Kojiro Mukai, Tomohiko Taguchi, Hiroaki Hemmi, Shizuo Akira, Kensuke Miyake

J Exp Med. 2023 Sep 4; 220(9): e20230054. Published online 2023 Jul 18. doi: 10.1084/jem.20230054

PMCID:: PMC10354536

Abstract Article PDF–6.5M

Select item 818338018.

TLR7 Signaling Drives the Development of Sjögren’s Syndrome

Yawen Wang, Annie Roussel-Queval, Lionel Chasson, Noël Hanna Kazazian, Laetitia Marcadet, Andrianos Nezos, Michael H. Sieweke, Clio Mavragani, Lena Alexopoulou

Front Immunol. 2021; 12: 676010. Published online 2021 May 24. doi: 10.3389/fimmu.2021.676010

PMCID:: PMC8183380

Abstract Article PDF–1.8M

Select item 512368819.

TLR8 couples SOCS-1 and restrains TLR7-mediated antiviral immunity exacerbating West Nile virus infection in mice

Amber M. Paul, Dhiraj Acharya, Linda Le, Penghua Wang, Dobrivoje S. Stokic, A. Arturo Leis, Lena Alexopoulou, Terrence Town, Richard A. Flavell, Erol Fikrig, Fengwei Bai

J Immunol. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: J Immunol. 2016 Dec 1; 197(11): 4425–4435. Published online 2016 Oct 21. doi: 10.4049/jimmunol.1600902

PMCID:: PMC5123688

Abstract Article PDF–1.8M

Select item 391060520.

TLR8 on dendritic cells and TLR9 on B cells restrain TLR7-mediated spontaneous autoimmunity in C57BL/6 mice

Benoit Desnues, Amanda Beatriz Macedo, Annie Roussel-Queval, Johnny Bonnardel, Sandrine Henri, Olivier Demaria, Lena Alexopoulou

Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4): 1497–1502. Published online 2014 Jan 13. doi: 10.1073/pnas.1314121111

PMCID:: PMC3910605

Abstract Article PDF–1.2M

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