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Select item 50092381.

NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length

Audrey Deligny, Tabea Dierker, Anders Dagälv, Anders Lundequist, Inger Eriksson, Alison V. Nairn, Kelley W. Moremen, Catherine L. R. Merry, Lena Kjellén

J Biol Chem. 2016 Sep 2; 291(36): 18600–18607. Published online 2016 Jul 7. doi: 10.1074/jbc.M116.744433

PMCID:: PMC5009238

Abstract Article PDF–1.7M

Select item 35167522.

N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland

Kevin T. Bush, Brett E. Crawford, Omai B. Garner, Kabir B. Nigam, Jeffrey D. Esko, Sanjay K. Nigam

J Biol Chem. 2012 Dec 7; 287(50): 42064–42070. Published online 2012 Oct 11. doi: 10.1074/jbc.M112.423327

PMCID:: PMC3516752

Abstract Article PDF–1.1M

Select item 33228443.

Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells

Maud Forsberg, Katarina Holmborn, Soumi Kundu, Anders Dagälv, Lena Kjellén, Karin Forsberg-Nilsson

J Biol Chem. 2012 Mar 30; 287(14): 10853–10862. Published online 2012 Feb 1. doi: 10.1074/jbc.M111.337030

PMCID:: PMC3322844

Abstract Article PDF–2.0M

Select item 33319184.

Functional overlap between chondroitin and heparan sulfate proteoglycans during VEGF-induced sprouting angiogenesis

Sébastien Le Jan, Makoto Hayashi, Zsolt Kasza, Inger Eriksson, Joseph R. Bishop, Irene Weibrecht, Johan Heldin, Katarina Holmborn, Lars Jakobsson, Ola Söderberg, Dorothe Spillmann, Jeffrey D. Esko, Lena Claesson-Welsh, Lena Kjellén, Johan Kreuger

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 May; 32(5): 1255–1263. Published online 2012 Feb 16. doi: 10.1161/ATVBAHA.111.240622

PMCID:: PMC3331918

Abstract Article PDF–2.4M

Select item 26691455.

Small changes in lymphocyte development and activation in mice through tissue-specific alteration of heparan sulphate

Omai B Garner, Yu Yamaguchi, Jeffrey D Esko, Vibeke Videm

Immunology. 2008 Nov; 125(3): 420–429. doi: 10.1111/j.1365-2567.2008.02856.x

PMCID:: PMC2669145

Abstract Article PDF–387K

Select item 66928686.

Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation

Yan Yin, Adam Wang, Li Feng, Yu Wang, Hong Zhang, Ivy Zhang, Brent M Bany, Liang Ma

Endocrinology. 2018 Jun; 159(6): 2459–2472. Published online 2018 Apr 23. doi: 10.1210/en.2018-00105

PMCID:: PMC6692868

Abstract Article

Select item 39194707.

Bioengineering murine mastocytoma cells to produce anticoagulant heparin

Leyla Gasimli, Charles A Glass, Payel Datta, Bo Yang, Guoyun Li, Trent R Gemmill, Jong Youn Baik, Susan T Sharfstein, Jeffrey D Esko, Robert J Linhardt

Glycobiology. 2014 Mar; 24(3): 272–280. Published online 2013 Dec 9. doi: 10.1093/glycob/cwt108

PMCID:: PMC3919470

Abstract Article PDF–450K

Select item 32480008.

Lowered Expression of Heparan Sulfate/Heparin Biosynthesis Enzyme N-Deacetylase/N-Sulfotransferase 1 Results in Increased Sulfation of Mast Cell Heparin

Anders Dagälv, Katarina Holmborn, Lena Kjellén, Magnus Åbrink

J Biol Chem. 2011 Dec 30; 286(52): 44433–44440. Published online 2011 Nov 2. doi: 10.1074/jbc.M111.303891

Correction in:: J Biol Chem. 2012 Mar 30; 287(14): 11282.

PMCID:: PMC3248000

Abstract Article PDF–1.8M

Select item 26103529.

Mast cells contribute to autoimmune inflammatory arthritis via their tryptase•heparin complexes

Kichul Shin, Peter A. Nigrovic, James Crish, Eric Boilard, H. Patrick McNeil, Katherine S. Larabee, Roberto Adachi, Michael F. Gurish, Reuben Gobezie, Richard L. Stevens, David M. Lee

J Immunol. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: J Immunol. 2009 Jan 1; 182(1): 647–656. doi: 10.4049/jimmunol.182.1.647

PMCID:: PMC2610352

Abstract Article PDF–2.6M

Select item 178512510.

Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development

Alexandra Abramsson, Sindhulakshmi Kurup, Marta Busse, Shuhei Yamada, Per Lindblom, Edith Schallmeiner, Denise Stenzel, Dominique Sauvaget, Johan Ledin, Maria Ringvall, Ulf Landegren, Lena Kjellén, Göran Bondjers, Jin-ping Li, Ulf Lindahl, Dorothe Spillmann, Christer Betsholtz, Holger Gerhardt

Genes Dev. 2007 Feb 1; 21(3): 316–331. doi: 10.1101/gad.398207

PMCID:: PMC1785125

Abstract Article PDF–1.7M

Select item 415670011.

Mannan induces ROS-regulated, IL-17A–dependent psoriasis arthritis-like disease in mice

Ia Khmaladze, Tiina Kelkka, Simon Guerard, Kajsa Wing, Angela Pizzolla, Amit Saxena, Katarina Lundqvist, Meirav Holmdahl, Kutty Selva Nandakumar, Rikard Holmdahl

Proc Natl Acad Sci U S A. 2014 Sep 2; 111(35): E3669–E3678. Published online 2014 Aug 18. doi: 10.1073/pnas.1405798111

PMCID:: PMC4156700

Abstract Article PDF–1.9M

Select item 927097312.

Chondroitin sulfate enhances the barrier function of basement membrane assembled by heparan sulfate

Chenqi Tao, Neoklis Makrides, Jen-Zen Chuang, Yihua Wu, Steven E. Brooks, Jeffrey D. Esko, Ching-Hwa Sung, Xin Zhang

Development. 2022 Jun 15; 149(12): dev200569. Published online 2022 Jun 16. doi: 10.1242/dev.200569

PMCID:: PMC9270973

Abstract Article

Select item 295100613.

Mast Cell Protease 5 Mediates Ischemia-Reperfusion Injury of Mouse Skeletal Muscle

J. Pablo Abonia, Daniel S. Friend, William G. Austen, Jr., Francis D. Moore, Jr., Michael C. Carroll, Rodney Chan, Jalil Afnan, Alison Humbles, Craig Gerard, Pamela Knight, Yoshihide Kanaoka, Shinsuke Yasuda, Nasa Morokawa, K. Frank Austen, Richard L. Stevens, Michael F. Gurish

J Immunol. Author manuscript; available in PMC 2010 Oct 7.

Published in final edited form as: J Immunol. 2005 Jun 1; 174(11): 7285–7291. doi: 10.4049/jimmunol.174.11.7285

PMCID:: PMC2951006

Abstract Article PDF–703K

Select item 242326314.

Altered Heparan Sulfate Structure in Mice with Deleted NDST3 Gene Function

Srinivas R. Pallerla, Roger Lawrence, Lars Lewejohann, Yi Pan, Tobias Fischer, Uwe Schlomann, Xin Zhang, Jeffrey D. Esko, Kay Grobe

J Biol Chem. 2008 Jun 13; 283(24): 16885–16894. doi: 10.1074/jbc.M709774200

PMCID:: PMC2423263

Abstract Article PDF–713K

Select item 400771415.

FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling

Chao Liu, Shuping Gu, Cheng Sun, Wenduo Ye, Zhongchen Song, Yanding Zhang, YiPing Chen

Development. 2013 Nov 1; 140(21): 4375–4385. doi: 10.1242/dev.097733

PMCID:: PMC4007714

Abstract Article

Select item 621436416.

A mutant cell library for systematic analysis of heparan sulfate structure-function relationships

Hong Qiu, Songshan Shi, Jingwen Yue, Meng Xin, Alison V Nairn, Lei Lin, Xinyue Liu, Guoyun Li, Stephanie A Archer-Hartmann, Mitche Dela Rosa, Melina Galizzi, Shunchun Wang, Fuming Zhang, Parastoo Azadi, Toin H. van Kuppevelt, Wellington V. Cardoso, Koji Kimata, Xingbin Ai, Kelley W Moremen, Jeffrey D. Esko, Robert J. Linhardt, Lianchun Wang

Nat Methods. Author manuscript; available in PMC 2019 Apr 30.

Published in final edited form as: Nat Methods. 2018 Nov; 15(11): 889–899. Published online 2018 Oct 30. doi: 10.1038/s41592-018-0189-6

PMCID:: PMC6214364

Abstract Article PDF–1.8M

Select item 310410917.

Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development

Xiuxia Qu, Kristina Hertzler, Yi Pan, Kay Grobe, Michael L. Robinson, Xin Zhang

Dev Biol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Dev Biol. 2011 Jul 1; 355(1): 12–20. Published online 2011 Apr 17. doi: 10.1016/j.ydbio.2011.04.007

PMCID:: PMC3104109

Abstract Article PDF–3.4M

Select item 1538818.

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

Craig McCormick, Gillian Duncan, K. Tina Goutsos, Frank Tufaro

Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2): 668–673. doi: 10.1073/pnas.97.2.668

PMCID:: PMC15388

Abstract Article PDF–321K

Select item 387954719.

Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Ananya Roy, Goutham Ganesh, Helena Sippola, Sara Bolin, Osama Sawesi, Anders Dagälv, Susan M. Schlenner, Thorsten Feyerabend, Hans-Reimer Rodewald, Lena Kjellén, Lars Hellman, Magnus Åbrink

J Biol Chem. 2014 Jan 3; 289(1): 237–250. Published online 2013 Nov 20. doi: 10.1074/jbc.M112.435156

PMCID:: PMC3879547

Abstract Article PDF–2.4M

Select item 417735820.

The Role of Heparan Sulfate Proteoglycans in Optic Disc and Stalk Morphogenesis

Zhigang Cai, Kay Grobe, Xin Zhang

Dev Dyn. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Dev Dyn. 2014 Oct; 243(10): 1310–1316. Published online 2014 May 6. doi: 10.1002/dvdy.24142

PMCID:: PMC4177358

Abstract Article PDF–2.0M

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PMC Links for Gene (Select 17423) (32)
PMC
RecName: Full=Uncharacterized protein YGR017W
RecName: Full=Uncharacterized protein YGR017W
gi|1723648|sp|P53210.1|YG1B_YEAST

Protein
Endocrine System
Endocrine System
The system of glands that release their secretions (hormones) directly into the circulatory system. In addition to the ENDOCRINE GLANDS, included are the CHROMAFFIN SYSTEM and...<br/>Year introduced: 1998

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