U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from Gene

Items: 1 to 20 of 61

1.
Targeting DNA2 overcomes metabolic reprogramming in multiple myeloma
Natthakan Thongon, Feiyang Ma, Natalia Baran, Pamela Lockyer, Jintan Liu, Christopher Jackson, Ashley Rose, Ken Furudate, Bethany Wildeman, Matteo Marchesini, Valentina Marchica, Paola Storti, Giannalisa Todaro, Irene Ganan-Gomez, Vera Adema, Juan Jose Rodriguez-Sevilla, Yun Qing, Min Jin Ha, Rodrigo Fonseca, Caleb Stein, Caleb Class, Lin Tan, Sergio Attanasio, Guillermo Garcia-Manero, Nicola Giuliani, David Berrios Nolasco, Andrea Santoni, Claudio Cerchione, Carlos Bueso-Ramos, Marina Konopleva, Philip Lorenzi, Koichi Takahashi, Elisabet Manasanch, Gabriella Sammarelli, Rashmi Kanagal-Shamanna, Andrea Viale, Marta Chesi, Simona Colla
Nat Commun. 2024; 15: 1203. Published online 2024 Feb 8. doi: 10.1038/s41467-024-45350-8
PMCID:
PMC10853245
AbstractArticlePDF–2.8M
2.
Estrogen upregulates DNA2 expression through the PI3K-AKT pathway in endometrial carcinoma
Xinyan WANG, Xiuling XU, Ting ZHANG, Yang JIN, Sheng XU, Lifeng CHEN, Yucheng LAI, Ling ZHANG, Ruolang PAN, Yan YU
J Zhejiang Univ Sci B. 2023 Mar 15; 24(3): 262–268. doi: 10.1631/jzus.B2200436
PMCID:
PMC10014318
ArticlePDF–1.3M
3.
The nuclease activity of DNA2 promotes exonuclease 1–independent mismatch repair
Lyudmila Y. Kadyrova, Basanta K. Dahal, Vaibhavi Gujar, James M. Daley, Patrick Sung, Farid A. Kadyrov
J Biol Chem. 2022 Apr; 298(4): 101831. Published online 2022 Mar 15. doi: 10.1016/j.jbc.2022.101831
PMCID:
PMC9036127
AbstractArticlePDF–1.2M
4.
Up-regulation of DNA2 results in cell proliferation and migration in endometriosis
Xinyan Wang, Wenjie Zeng, Sheng Xu, Jingya Nie, Lu Huang, Yucheng Lai, Yan Yu
J Mol Histol. 2021; 52(4): 741–749. Published online 2021 May 28. doi: 10.1007/s10735-021-09983-z
PMCID:
PMC8324585
AbstractArticlePDF–1.1M
5.
Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer
Yingyan Han, Zeyu Zhang, Zhi Wang, Shujuan Sun
Dis Markers. 2021; 2021: 8860728. Published online 2021 Jan 26. doi: 10.1155/2021/8860728
PMCID:
PMC7857872
AbstractArticlePDF–2.7M
6.
Limiting homologous recombination at stalled replication forks is essential for cell viability: DNA2 to the rescue
Rowin Appanah, David Jones, Benoît Falquet, Ulrich Rass
Curr Genet. 2020; 66(6): 1085–1092. Published online 2020 Sep 9. doi: 10.1007/s00294-020-01106-7
PMCID:
PMC7599155
AbstractArticlePDF–874K
7.
The iron–sulphur cluster in human DNA2 is required for all biochemical activities of DNA2
Laura Mariotti, Sebastian Wild, Giulia Brunoldi, Alessandra Piceni, Ilaria Ceppi, Sandra Kummer, Richard E. Lutz, Petr Cejka, Kerstin Gari
Commun Biol. 2020; 3: 322. Published online 2020 Jun 23. doi: 10.1038/s42003-020-1048-4
PMCID:
PMC7311471
AbstractArticlePDF–1.7M
8.
Multiple roles of DNA2 nuclease/helicase in DNA metabolism, genome stability and human diseases
Li Zheng, Yuan Meng, Judith L Campbell, Binghui Shen
Nucleic Acids Res. 2020 Jan 10; 48(1): 16–35. Published online 2019 Nov 22. doi: 10.1093/nar/gkz1101
PMCID:
PMC6943134
AbstractArticlePDF–2.0M
9.
hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability
Zhengke Li, Bochao Liu, Weiwei Jin, Xiwei Wu, Mian Zhou, Vincent Zewen Liu, Ajay Goel, Zhiyuan Shen, Li Zheng, Binghui Shen
EMBO J. 2018 Jul 13; 37(14): e96729. Published online 2018 May 17. doi: 10.15252/embj.201796729
PMCID:
PMC6043852
AbstractArticlePDF–2.9M
10.
DNA2 drives processing and restart of reversed replication forks in human cells
Saravanabhavan Thangavel, Matteo Berti, Maryna Levikova, Cosimo Pinto, Shivasankari Gomathinayagam, Marko Vujanovic, Ralph Zellweger, Hayley Moore, Eu Han Lee, Eric A. Hendrickson, Petr Cejka, Sheila Stewart, Massimo Lopes, Alessandro Vindigni
J Cell Biol. 2015 Mar 2; 208(5): 545–562. doi: 10.1083/jcb.201406100
PMCID:
PMC4347643
AbstractArticlePDF–4.7M
11.
The DNA2 nuclease/helicase is an estrogen-dependent gene mutated in breast and ovarian cancers
Carmit Strauss, Maya Kornowski, Avraham Benvenisty, Amit Shahar, Hadas Masury, Ittai Ben-Porath, Tommer Ravid, Ayelet Arbel-Eden, Michal Goldberg
Oncotarget. 2014 Oct; 5(19): 9396–9409. Published online 2014 Nov 1. doi: 10.18632/oncotarget.2414
PMCID:
PMC4253442
AbstractArticlePDF–1.5M
12.
Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells
Kenneth K Karanja, Eu Han Lee, Eric A Hendrickson, Judith L Campbell
Cell Cycle. 2014 May 15; 13(10): 1540–1550. Published online 2014 Mar 12. doi: 10.4161/cc.28476
PMCID:
PMC4050159
AbstractArticlePDF–1.8M
13.
Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1
Jason W. Gloor, Lata Balakrishnan, Judith L. Campbell, Robert A. Bambara
Nucleic Acids Res. 2012 Aug; 40(14): 6774–6786. Published online 2012 May 8. doi: 10.1093/nar/gks388
PMCID:
PMC3413157
AbstractArticlePDF–10M
14.
Okazaki Fragment Processing-independent Role for Human Dna2 Enzyme during DNA Replication
Julien P. Duxin, Hayley R. Moore, Julia Sidorova, Kenneth Karanja, Yuchi Honaker, Benjamin Dao, Helen Piwnica-Worms, Judith L. Campbell, Raymond J. Monnat, Jr., Sheila A. Stewart
J Biol Chem. 2012 Jun 22; 287(26): 21980–21991. Published online 2012 May 7. doi: 10.1074/jbc.M112.359018
PMCID:
PMC3381158
AbstractArticlePDF–2.0M
15.
Human Dna2 Is a Nuclear and Mitochondrial DNA Maintenance Protein
Julien P. Duxin, Benjamin Dao, Peter Martinsson, Nina Rajala, Lionel Guittat, Judith L. Campbell, Johannes N. Spelbrink, Sheila A. Stewart
Mol Cell Biol. 2009 Aug; 29(15): 4274–4282. Published online 2009 Jun 1. doi: 10.1128/MCB.01834-08
PMCID:
PMC2715806
AbstractArticlePDF–1.6M
16.
Biochemical analysis of human Dna2
Taro Masuda-Sasa, Osamu Imamura, Judith L. Campbell
Nucleic Acids Res. 2006; 34(6): 1865–1875. Published online 2006 Apr 4. doi: 10.1093/nar/gkl070
PMCID:
PMC1428797
AbstractArticlePDF–3.2M
17.
Isolation of human Dna2 endonuclease and characterization of its enzymatic properties
Jeong-Hoon Kim, Hee-Dai Kim, Gi-Hyuck Ryu, Do-Hyung Kim, Jerard Hurwitz, Yeon-Soo Seo
Nucleic Acids Res. 2006; 34(6): 1854–1864. Published online 2006 Apr 4. doi: 10.1093/nar/gkl102
PMCID:
PMC1428795
AbstractArticlePDF–1.3M
18.
CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection
Ilaria Ceppi, Sean M. Howard, Kristina Kasaciunaite, Cosimo Pinto, Roopesh Anand, Ralf Seidel, Petr Cejka
Proc Natl Acad Sci U S A. 2020 Apr 21; 117(16): 8859–8869. Published online 2020 Apr 2. doi: 10.1073/pnas.2001165117
PMCID:
PMC7183222
AbstractArticlePDF–1.9M
19.
TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity
Yuan Meng, Changwei Liu, Lei Shen, Mian Zhou, Wenpeng Liu, Claudia Kowolik, Judith L Campbell, Li Zheng, Binghui Shen
Nucleic Acids Res. 2019 Aug 22; 47(14): 7564–7579. Published online 2019 Jun 19. doi: 10.1093/nar/gkz537
PMCID:
PMC6698806
AbstractArticlePDF–10M
20.
Mutations in DNA2 Link Progressive Myopathy to Mitochondrial DNA Instability
Dario Ronchi, Alessio Di Fonzo, Weiqiang Lin, Andreina Bordoni, Changwei Liu, Elisa Fassone, Serena Pagliarani, Mafalda Rizzuti, Li Zheng, Massimiliano Filosto, Maria Teresa Ferrò, Michela Ranieri, Francesca Magri, Lorenzo Peverelli, Hongzhi Li, Yate-Ching Yuan, Stefania Corti, Monica Sciacco, Maurizio Moggio, Nereo Bresolin, Binghui Shen, Giacomo Pietro Comi
Am J Hum Genet. 2013 Feb 7; 92(2): 293–300. doi: 10.1016/j.ajhg.2012.12.014
PMCID:
PMC3567272
AbstractArticlePDF–884K

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center