PMC Links for Gene (Select 1806) - PMC

Result Filters

Links from Gene

Items: 1 to 20 of 84

<< First< Prev

Page of 5

Select item 110607111.

Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)

Ting Zhang, Alisa Ambrodji, Huixing Huang, Kelly J Bouchonville, Amy S Etheridge, Remington E Schmidt, Brianna M Bembenek, Zoey B Temesgen, Zhiquan Wang, Federico Innocenti, Deborah Stroka, Robert B Diasio, Carlo R Largiadèr, Steven M Offer

eLife. 2024; 13: RP94075. Published online 2024 Apr 30. doi: 10.7554/eLife.94075

PMCID:: PMC11060711

Abstract Article PDF–1.0M

Select item 107867222.

Integrating rare genetic variants into DPYD pharmacogenetic testing may help preventing fluoropyrimidine-induced toxicity

Romain Larrue, Sandy Fellah, Benjamin Hennart, Naoual Sabaouni, Nihad Boukrout, Cynthia Van der Hauwaert, Clément Delage, Meyling Cheok, Michaël Perrais, Christelle Cauffiez, Delphine Allorge, Nicolas Pottier

Pharmacogenomics J. 2024; 24(1): 1. Published online 2024 Jan 12. doi: 10.1038/s41397-023-00322-x

PMCID:: PMC10786722

Abstract Article PDF–814K

Select item 102655963.

Impact of renal impairment on dihydropyrimidine dehydrogenase (DPD) phenotyping

B. Royer, M. Launay, J. Ciccolini, L. Derain, F. Parant, F. Thomas, J. Guitton

ESMO Open. 2023 Jun; 8(3): 101577. Published online 2023 May 31. doi: 10.1016/j.esmoop.2023.101577

PMCID:: PMC10265596

Abstract Article PDF–498K

Select item 101661674.

Allelic Frequency of DPYD Genetic Variants in Patients With Cancer in Spain: The PhotoDPYD Study

Marta Miarons, Alba Manzaneque Gordón, Pau Riera, Fernando Gutiérrez Nicolás, in Collaboration with the RedDPYD Research Group with the Spanish Society of Hospital Pharmacy (SEFH)

Oncologist. 2023 May; 28(5): e304–e308. Published online 2023 Apr 4. doi: 10.1093/oncolo/oyad077

PMCID:: PMC10166167

Abstract Article PDF–2.5M

Select item 101343045.

Poor association between dihydropyrimidine dehydrogenase (DPYD) genotype and fluoropyrimidine‐induced toxicity in an Asian population

Masashi Kanai, Takahisa Kawaguchi, Masahito Kotaka, Dai Manaka, Junichi Hasegawa, Akinori Takagane, Yoshinori Munemoto, Takeshi Kato, Tetsuya Eto, Tetsuo Touyama, Takanori Matsui, Katsunori Shinozaki, Shigemi Matsumoto, Tsunekazu Mizushima, Masaki Mori, Junichi Sakamoto, Atsushi Ohtsu, Takayuki Yoshino, Shigetoyo Saji, Fumihiko Matsuda

Cancer Med. 2023 Apr; 12(7): 7808–7814. Published online 2022 Dec 16. doi: 10.1002/cam4.5541

PMCID:: PMC10134304

Abstract Article PDF–196K

Select item 98576856.

DPYD Exon 4 Deletion Associated with Fluoropyrimidine Toxicity and Importance of Copy Number Variation

Theodore J. Wigle, Samantha Medwid, Cameron Ross, Ute I. Schwarz, Richard B. Kim

Curr Oncol. 2023 Jan; 30(1): 663–672. Published online 2023 Jan 4. doi: 10.3390/curroncol30010051

PMCID:: PMC9857685

Abstract Article PDF–427K

Select item 98103217.

Pharmacogenetic Study of the Dihydropyridine Dehydrogenase Gene in Jordanian Patients with Colorectal Cancer

Nusaiba A. Almashagbah, Amjad A. Mahasneh, Khaldon G. Bodoor

Asian Pac J Cancer Prev. 2022 Sep; 23(9): 3061–3069. doi: 10.31557/APJCP.2022.23.9.3061

PMCID:: PMC9810321

Abstract Article PDF–773K

Select item 88855588.

Consensus of experts from the Spanish Pharmacogenetics and Pharmacogenomics Society and the Spanish Society of Medical Oncology for the genotyping of DPYD in cancer patients who are candidates for treatment with fluoropyrimidines

P. García-Alfonso, M. Saiz-Rodríguez, R. Mondéjar, J. Salazar, D. Páez, A. M. Borobia, M. J. Safont, I. García-García, R. Colomer, X. García-González, M. J. Herrero, L. A. López-Fernández, F. Abad-Santos

Clin Transl Oncol. 2022; 24(3): 483–494. Published online 2021 Nov 13. doi: 10.1007/s12094-021-02708-4

PMCID:: PMC8885558

Abstract Article PDF–926K

Select item 86051729.

Dihydropyrimidine dehydrogenase (DPYD) gene c.1627A>G A/G and G/G genotypes are risk factors for lymph node metastasis and distant metastasis of colorectal cancer

Juanzi Zeng, Heming Wu, Qingyan Huang, Jiaquan Li, Zhikang Yu, Zhixiong Zhong

J Clin Lab Anal. 2021 Nov; 35(11): e24023. Published online 2021 Oct 6. doi: 10.1002/jcla.24023

PMCID:: PMC8605172

Abstract Article PDF–421K

Select item 838230410.

DPYD Genotyping in Patients Who Have Planned Cancer Treatment With Fluoropyrimidines: A Health Technology Assessment

Ontario Health (Quality)

Ont Health Technol Assess Ser. 2021; 21(14): 1–186. Published online 2021 Aug 12.

PMCID:: PMC8382304

Abstract Article PDF–2.6M

Select item 828373511.

DPYD, down-regulated by the potentially chemopreventive agent luteolin, interacts with STAT3 in pancreatic cancer

Hiroyuki Kato, Aya Naiki-Ito, Shugo Suzuki, Shingo Inaguma, Masayuki Komura, Kenju Nakao, Taku Naiki, Kenta Kachi, Akihisa Kato, Yoichi Matsuo, Satoru Takahashi

Carcinogenesis. 2021 Jul; 42(7): 940–950. Published online 2021 Feb 26. doi: 10.1093/carcin/bgab017

PMCID:: PMC8283735

Abstract Article PDF–20M

Select item 783188512.

Case report: severe toxicity in an African–American patient receiving FOLFOX carrying uncommon allelic variants in DPYD

Tristan M Sissung, Lisa Cordes, Cody J Peer, Shruti Gandhy, Jason Redman, Julius Strauss, William D Figg

Pharmacogenomics. 2021 Jan; 22(2): 81–85. Published online 2020 Dec 11. doi: 10.2217/pgs-2020-0120

PMCID:: PMC7831885

Abstract Article PDF–426K

Select item 729879813.

Evaluation of adverse effects of chemotherapy regimens of 5-fluoropyrimidines derivatives and their association with DPYD polymorphisms in colorectal cancer patients

Reza Negarandeh, Ebrahim Salehifar, Fatemeh Saghafi, Hossein Jalali, Ghasem Janbabaei, Mohammad Javad Abdhaghighi, Anahita Nosrati

BMC Cancer. 2020; 20: 560. Published online 2020 Jun 16. doi: 10.1186/s12885-020-06904-3

PMCID:: PMC7298798

Abstract Article PDF–278K

Select item 699651514.

Fluorouracil sensitivity in a head and neck squamous cell carcinoma with a somatic DPYD structural variant

Elisa Majounie, Kathleen Wee, Laura M. Williamson, Martin R. Jones, Erin Pleasance, Howard J. Lim, Cheryl Ho, Daniel J. Renouf, Stephen Yip, Steven J.M. Jones, Marco A. Marra, Janessa Laskin

Cold Spring Harb Mol Case Stud. 2020 Feb; 6(1): a004713. doi: 10.1101/mcs.a004713

PMCID:: PMC6996515

Abstract Article PDF–2.0M

Select item 698268415.

Influence of DPYD*9A, DPYD*6 and GSTP1 ile105val Genetic Polymorphisms on Capecitabine and Oxaliplatin (CAPOX) Associated Toxicities in Colorectal Cancer (CRC) Patients

Ashok Varma K, M Jayanthi, Biswajit Dubashi, D G Shewade

Asian Pac J Cancer Prev. 2019; 20(10): 3093–3100. doi: 10.31557/APJCP.2019.20.10.3093

PMCID:: PMC6982684

Abstract Article PDF–405K

Select item 653321916.

Clinical implementation of pre-treatment DPYD genotyping in capecitabine-treated metastatic breast cancer patients

Chara Stavraka, Athanasios Pouptsis, Leroy Okonta, Karen DeSouza, Philip Charlton, Matthaios Kapiris, Anthony Marinaki, Eleni Karapanagiotou, Dionysis Papadatos-Pastos, Janine Mansi

Breast Cancer Res Treat. 2019; 175(2): 511–517. Published online 2019 Feb 12. doi: 10.1007/s10549-019-05144-9

PMCID:: PMC6533219

Abstract Article PDF–554K

Select item 592671817.

Germline Mutation of Dihydropyrimidine Dehydrogenese Gene among a Japanese Population in Relation to Toxicity to 5‐Fluorouracil

Kensei Yamaguchi, Yoshiko Aral, Yuzo Kanda, Kiwamu Akagi

Jpn J Cancer Res. 2001 Mar; 92(3): 337–342. doi: 10.1111/j.1349-7006.2001.tb01100.x

PMCID:: PMC5926718

Summary PDF–522K

Select item 583363418.

Dihydropyrimidine dehydrogenase predicts survival and response to interferon-α in hepatocellular carcinoma

Wei-Ping Zhu, Ze-Yang Liu, Yi-Ming Zhao, Xi-Gan He, Qi Pan, Ning Zhang, Jia-Min Zhou, Long-Rong Wang, Miao Wang, Di-Hua Zhan, De-Ning Ma, Lu Wang

Cell Death Dis. 2018 Feb; 9(2): 69. Published online 2018 Jan 22. doi: 10.1038/s41419-017-0098-0

PMCID:: PMC5833634

Abstract Article PDF–3.6M

Select item 570967219.

Dihydropyrimidine dehydrogenase pharmacogenetics for predicting fluoropyrimidine-related toxicity in the randomised, phase III adjuvant TOSCA trial in high-risk colon cancer patients

A Ruzzo, F Graziano, Fabio Galli, Francesca Galli, E Rulli, S Lonardi, M Ronzoni, B Massidda, V Zagonel, N Pella, C Mucciarini, R Labianca, M T Ionta, I Bagaloni, E Veltri, P Sozzi, S Barni, V Ricci, L Foltran, M Nicolini, E Biondi, A Bramati, D Turci, S Lazzarelli, C Verusio, F Bergamo, A Sobrero, L Frontini, M Menghi, M Magnani

Br J Cancer. 2017 Oct 24; 117(9): 1269–1277. Published online 2017 Aug 24. doi: 10.1038/bjc.2017.289