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Select item 111601561.

Amplification, up‐regulation and over‐expression of DVL‐1, the human counterpart of the Drosophila disheveled gene, in primary breast cancers

Takemitsu Nagahata, Takashi Shimada, Akima Harada, Hisaki Nagai, Masamitsu Onda, Shiro Yokoyama, Tadayoshi Shiba, Enjing Jin, Oichi Kawanami, Mitsuru Emi

Cancer Sci. 2003 Jun; 94(6): 515–518. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01475.x

PMCID:: PMC11160156

Abstract Article PDF–282K

Select item 101649142.

The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation

Heather S. Carr, Yan Zuo, Jeffrey A. Frost

J Biol Chem. 2023 May; 299(5): 104645. Published online 2023 Mar 23. doi: 10.1016/j.jbc.2023.104645

PMCID:: PMC10164914

Abstract Article PDF–4.1M

Select item 85846353.

Decoding the Role of DVL1 in Intracranial Meningioma

Anja Bukovac, Katarina Dragičević, Anja Kafka, Darko Orešković, Sanja Cesarec-Augustinović, Nives Pećina-Šlaus

Int J Mol Sci. 2021 Nov; 22(21): 11996. Published online 2021 Nov 5. doi: 10.3390/ijms222111996

PMCID:: PMC8584635

Abstract Article PDF–2.5M

Select item 70663624.

Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma

Wen-Ying Liao, Chung-Chi Hsu, Tze-Sian Chan, Chia-Jui Yen, Wei-Yu Chen, Hung-Wei Pan, Kelvin K. Tsai

Stem Cell Reports. 2020 Mar 10; 14(3): 462–477. Published online 2020 Mar 10. doi: 10.1016/j.stemcr.2020.02.003

PMCID:: PMC7066362

Abstract Article PDF–4.8M

Select item 65905235.

Oxidative stress upregulates Wnt signaling in human retinal microvascular endothelial cells through activation of disheveled

Chi Zhang, Elizabeth Tannous, Jie J. Zheng

J Cell Biochem. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Cell Biochem. 2019 Aug; 120(8): 14044–14054. Published online 2019 Apr 8. doi: 10.1002/jcb.28679

PMCID:: PMC6590523

Abstract Article PDF–1.4M

Select item 64955466.

Silencing dishevelled‐1 sensitizes paclitaxel‐resistant human ovarian cancer cells via AKT/GSK‐3β/β‐catenin signalling

Kun Zhang, Haixing Song, Ping Yang, Xiaozhen Dai, Ya Li, Lan Wang, Jun Du, Kejian Pan, Tao Zhang

Cell Prolif. 2015 Apr; 48(2): 249–258. Published online 2015 Jan 21. doi: 10.1111/cpr.12161

PMCID:: PMC6495546

Abstract Article PDF–1.2M

Select item 43851937.

Mutations in DVL1 Cause an Osteosclerotic Form of Robinow Syndrome

Kieran J. Bunn, Phil Daniel, Heleen S. Rösken, Adam C. O’Neill, Sophia R. Cameron-Christie, Tim Morgan, Han G. Brunner, Angeline Lai, Henricus P.M. Kunst, David M. Markie, Stephen P. Robertson

Am J Hum Genet. 2015 Apr 2; 96(4): 623–630. doi: 10.1016/j.ajhg.2015.02.010

PMCID:: PMC4385193

Abstract Article PDF–622K

Select item 43851808.

DVL1 Frameshift Mutations Clustering in the Penultimate Exon Cause Autosomal-Dominant Robinow Syndrome

Janson White, Juliana F. Mazzeu, Alexander Hoischen, Shalini N. Jhangiani, Tomasz Gambin, Michele Calijorne Alcino, Samantha Penney, Jorge M. Saraiva, Hanne Hove, Flemming Skovby, Hülya Kayserili, Elicia Estrella, Anneke T. Vulto-van Silfhout, Marloes Steehouwer, Donna M. Muzny, V. Reid Sutton, Richard A. Gibbs, Baylor-Hopkins Center for Mendelian Genomics, James R. Lupski, Han G. Brunner, Bregje W.M. van Bon, Claudia M.B. Carvalho

Am J Hum Genet. 2015 Apr 2; 96(4): 612–622. doi: 10.1016/j.ajhg.2015.02.015

PMCID:: PMC4385180

Abstract Article PDF–953K

Select item 38216279.

Significant Overexpression of DVL1 in Taiwanese Colorectal Cancer Patients with Liver Metastasis

Ming-Yii Huang, Li-Chen Yen, Hsueh-Chiao Liu, Po-Ping Liu, Fu-Yen Chung, Tsu-Nai Wang, Jaw-Yuan Wang, Shiu-Ru Lin

Int J Mol Sci. 2013 Oct; 14(10): 20492–20507. Published online 2013 Oct 14. doi: 10.3390/ijms141020492

PMCID:: PMC3821627

Abstract Article PDF–870K

Select item 912002510.

DVL1 and DVL3 require nuclear localisation to regulate proliferation in human myoblasts

Johanna Pruller, Nicolas Figeac, Peter S. Zammit

Sci Rep. 2022; 12: 8388. Published online 2022 May 19. doi: 10.1038/s41598-022-10536-x

PMCID:: PMC9120025

Abstract Article PDF–13M

Select item 863755311.

FUBP1 promotes colorectal cancer stemness and metastasis via DVL1‐mediated activation of Wnt/β‐catenin signaling

Haofan Yin, Tianxiao Gao, Jinye Xie, Zhijian Huang, Xiaoyan Zhang, Fengyu Yang, Weiwei Qi, Zhonghan Yang, Ti Zhou, Guoquan Gao, Xia Yang

Mol Oncol. 2021 Dec; 15(12): 3490–3512. Published online 2021 Jul 29. doi: 10.1002/1878-0261.13064

PMCID:: PMC8637553

Abstract Article PDF–13M

Select item 733389212.

Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12

Zhuoyao Chen, Gregory A. Wasney, Sarah Picaud, Panagis Filippakopoulos, Masoud Vedadi, Vincenzo D'Angiolella, Alex N. Bullock

Open Biol. 2020 Jun; 10(6): 200041. Published online 2020 Jun 24. doi: 10.1098/rsob.200041

PMCID:: PMC7333892

Abstract Article PDF–1.9M

Select item 599765013.

Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner

Yoonmi Lee, Nam Hee Kim, Eunae Sandra Cho, Ji Hye Yang, Yong Hoon Cha, Hee Eun Kang, Jun Seop Yun, Sue Bean Cho, Seon-Hyeong Lee, Petra Paclikova, Tomasz W. Radaszkiewicz, Vitezslav Bryja, Chi Gu Kang, Young Soo Yuk, So Young Cha, Soo-Youl Kim, Hyun Sil Kim, Jong In Yook

Nat Commun. 2018; 9: 2301. Published online 2018 Jun 12. doi: 10.1038/s41467-018-04757-w

PMCID:: PMC5997650

Abstract Article PDF–9.9M

Select item 499596514.

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins

Igor Cervenka, Jana Valnohova, Ondrej Bernatik, Jakub Harnos, Matej Radsetoulal, Katerina Sedova, Katerina Hanakova, David Potesil, Miroslava Sedlackova, Alena Salasova, Zachary Steinhart, Stephane Angers, Gunnar Schulte, Ales Hampl, Zbynek Zdrahal, Vitezslav Bryja

Proc Natl Acad Sci U S A. 2016 Aug 16; 113(33): 9304–9309. Published online 2016 Aug 2. doi: 10.1073/pnas.1608783113

PMCID:: PMC4995965

Abstract Article PDF–1.0M

Select item 497697615.

Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I

Randall A. Dass, Aishe A. Sarshad, Brittany B. Carson, Jennifer M. Feenstra, Amanpreet Kaur, Ales Obrdlik, Matthew M. Parks, Varsha Prakash, Damon K. Love, Kristian Pietras, Rosa Serra, Scott C. Blanchard, Piergiorgio Percipalle, Anthony M. C. Brown, C. Theresa Vincent

PLoS Genet. 2016 Aug; 12(8): e1006217. Published online 2016 Aug 8. doi: 10.1371/journal.pgen.1006217

PMCID:: PMC4976976

Abstract Article PDF–14M

Select item 493346916.

Receptor for Activated C Kinase 1 (RACK1) Promotes Dishevelled Protein Degradation via Autophagy and Antagonizes Wnt Signaling

Minzhang Cheng, Hua Xue, Weipeng Cao, Wenxia Li, Hua Chen, Bofeng Liu, Benyu Ma, Xiaohua Yan, Ye-Guang Chen

J Biol Chem. 2016 Jun 10; 291(24): 12871–12879. Published online 2016 Apr 20. doi: 10.1074/jbc.M115.708818

PMCID:: PMC4933469

Abstract Article PDF–3.6M

Select item 480004417.

DVL3 Alleles Resulting in a −1 Frameshift of the Last Exon Mediate Autosomal-Dominant Robinow Syndrome

Janson J. White, Juliana F. Mazzeu, Alexander Hoischen, Yavuz Bayram, Marjorie Withers, Alper Gezdirici, Virginia Kimonis, Marloes Steehouwer, Shalini N. Jhangiani, Donna M. Muzny, Richard A. Gibbs, Baylor-Hopkins Center for Mendelian Genomics, Bregje W.M. van Bon, V. Reid Sutton, James R. Lupski, Han G. Brunner, Claudia M.B. Carvalho

Am J Hum Genet. 2016 Mar 3; 98(3): 553–561. Published online 2016 Feb 25. doi: 10.1016/j.ajhg.2016.01.005