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Select item 98119981.

Dishevelled phase separation promotes Wnt signalosome assembly and destruction complex disassembly

Kexin Kang, Qiaoni Shi, Xu Wang, Ye-Guang Chen

J Cell Biol. 2022 Dec 5; 221(12): e202205069. Published online 2022 Nov 7. doi: 10.1083/jcb.202205069

PMCID:: PMC9811998

Abstract Article PDF–4.3M

Select item 82560322.

Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites

Gonzalo J. Beitia, Trevor J. Rutherford, Stefan M. V. Freund, Hugh R. Pelham, Mariann Bienz, Melissa V. Gammons

Proc Natl Acad Sci U S A. 2021 Jun 29; 118(26): e2103258118. Published online 2021 Jun 21. doi: 10.1073/pnas.2103258118

PMCID:: PMC8256032

Abstract Article PDF–1.9M

Select item 73383943.

Reversible acetylation modulates dishevelled-2 puncta formation in canonical Wnt signaling activation

Jinhong Shen, Lin Hu, Li Yang, Mengshi Zhang, Weihong Sun, Xiaomei Lu, Gufa Lin, Chao Huang, Xiaoren Zhang, Y. Eugene Chin

Signal Transduct Target Ther. 2020; 5: 115. Published online 2020 Jul 6. doi: 10.1038/s41392-020-00229-0

PMCID:: PMC7338394

Article PDF–1.6M

Select item 60596814.

Dishevelled-2 modulates osteogenic differentiation of human synovial fibroblasts in osteoarthritis

Lihua Zhang, Luan Luan, Yingying Ma

Mol Med Rep. 2018 Jul; 18(1): 292–298. Published online 2018 May 4. doi: 10.3892/mmr.2018.8975

PMCID:: PMC6059681

Abstract Article PDF–1.1M

Select item 32288975.

Dishevelled 2 signaling promotes self-renewal and tumorigenicity in human gliomas

Teodoro Pulvirenti, Maartje Van Der Heijden, Leif A. Droms, Jason T. Huse, Viviane Tabar, Alan Hall

Cancer Res. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Cancer Res. 2011 Dec 1; 71(23): 7280–7290. Published online 2011 Oct 11. doi: 10.1158/0008-5472.CAN-11-1531

PMCID:: PMC3228897

Abstract Article PDF–2.4M

Select item 110765556.

Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF

Aishwarya Omble, Shrutika Mahajan, Ashwini Bhoite, Kiran Kulkarni

Commun Biol. 2024; 7: 543. Published online 2024 May 7. doi: 10.1038/s42003-024-06194-6

PMCID:: PMC11076555

Abstract Article PDF–3.6M

Select item 88193047.

Dvl2 facilitates the coordination of NF‐κB and Wnt signaling to promote colitis‐associated colorectal progression

Feiyu Tang, Fuyang Cao, Can Lu, Xiang He, Liang Weng, Lunquan Sun

Cancer Sci. 2022 Feb; 113(2): 565–575. Published online 2021 Dec 15. doi: 10.1111/cas.15206

PMCID:: PMC8819304

Abstract Article PDF–1.4M

Select item 79339258.

TM4SF1, a binding protein of DVL2 in hepatocellular carcinoma, positively regulates beta‐catenin/TCF signalling

ChuanrRong Zhu, XiaoLing Luo, JinSheng Wu, YuTing Liu, Lei Liu, ShiJie Ma, Rui Xie, ShaoChuang Wang, Wu Ji

J Cell Mol Med. 2021 Mar; 25(5): 2356–2364. Published online 2019 Dec 26. doi: 10.1111/jcmm.14787

PMCID:: PMC7933925

Abstract Article PDF–1.3M

Select item 73682859.

Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation

Wenzhe Ma, Maorong Chen, Hong Kang, Zachary Steinhart, Stephane Angers, Xi He, Marc W. Kirschner

Proc Natl Acad Sci U S A. 2020 Jul 14; 117(28): 16690–16701. Published online 2020 Jun 29. doi: 10.1073/pnas.1910547117

PMCID:: PMC7368285

Abstract Article PDF–1.7M

Select item 535504210.

Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway

Xing Zhen Liu, Jie Fan, Ke Qi, Shu Peng Liu, Wei Dong Xu, Ying Gao, Xiao Dan Gu, Jia Li, Chen Guang Bai, Ye Qing Shi, Lan Ling Zhang, Dong Bao Zhao

Oncotarget. 2017 Feb 21; 8(8): 12649–12663. Published online 2017 Feb 7. doi: 10.18632/oncotarget.15172

PMCID:: PMC5355042

Abstract Article PDF–10M

Select item 360564711.

HECT Domain-containing E3 Ubiquitin Ligase NEDD4L Negatively Regulates Wnt Signaling by Targeting Dishevelled for Proteasomal Degradation

Yi Ding, Yan Zhang, Chao Xu, Qing-Hua Tao, Ye-Guang Chen

J Biol Chem. 2013 Mar 22; 288(12): 8289–8298. Published online 2013 Feb 9. doi: 10.1074/jbc.M112.433185

PMCID:: PMC3605647

Abstract Article PDF–4.0M

Select item 356638812.

Genetic Analysis of Disheveled 2 and Disheveled 3 in Human Neural Tube Defects

Patrizia De Marco, Elisa Merello, Alessandro Consales, Gianluca Piatelli, Armando Cama, Zoha Kibar, Valeria Capra

J Mol Neurosci. 2013 Mar; 49(3): 582–588. Published online 2012 Aug 15. doi: 10.1007/s12031-012-9871-9

PMCID:: PMC3566388

Abstract Article PDF–161K

Select item 906694113.

CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling

Lili Zhu, Xiaobei Yang, Jingyu Feng, Jian Mao, Qidong Zhang, Mengru He, Yang Mi, Yingwu Mei, Ge Jin, Haifeng Zhang

J Transl Med. 2022; 20: 194. Published online 2022 May 4. doi: 10.1186/s12967-022-03396-6

PMCID:: PMC9066941

Abstract Article PDF–14M

Select item 881693714.

HBx increases chromatin accessibility and ETV4 expression to regulate dishevelled-2 and promote HCC progression

Chuqian Zheng, Min Liu, Yanping Ge, Yanyan Qian, Hong Fan

Cell Death Dis. 2022 Feb; 13(2): 116. Published online 2022 Feb 4. doi: 10.1038/s41419-022-04563-9

PMCID:: PMC8816937

Abstract Article PDF–4.9M

Select item 701413515.

TBX1 and Basal Cell Carcinoma: Expression and Interactions with Gli2 and Dvl2 Signaling

Cinzia Caprio, Silvia Varricchio, Marchesa Bilio, Federica Feo, Rosa Ferrentino, Daniela Russo, Stefania Staibano, Daniela Alfano, Caterina Missero, Gennaro Ilardi, Antonio Baldini

Int J Mol Sci. 2020 Jan; 21(2): 607. Published online 2020 Jan 17. doi: 10.3390/ijms21020607

PMCID:: PMC7014135

Abstract Article PDF–8.0M

Select item 508765816.

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

Melissa V. Gammons, Trevor J. Rutherford, Zachary Steinhart, Stephane Angers, Mariann Bienz

J Cell Sci. 2016 Oct 15; 129(20): 3892–3902. doi: 10.1242/jcs.195685

PMCID:: PMC5087658

Abstract Article

Select item 361101317.

Atypical Protein Kinase Cι Is Required for Wnt3a-dependent Neurite Outgrowth and Binds to Phosphorylated Dishevelled 2

Yoshimi Endo Greer, Alan P. Fields, Anthony M. C. Brown, Jeffrey S. Rubin

J Biol Chem. 2013 Mar 29; 288(13): 9438–9446. Published online 2013 Feb 8. doi: 10.1074/jbc.M112.448282

PMCID:: PMC3611013

Abstract Article PDF–2.7M

Select item 330726918.

Malin Regulates Wnt Signaling Pathway through Degradation of Dishevelled2

Jaiprakash Sharma, Shalaka Mulherkar, Diptendu Mukherjee, Nihar Ranjan Jana

J Biol Chem. 2012 Feb 24; 287(9): 6830–6839. Published online 2012 Jan 5. doi: 10.1074/jbc.M111.315135

PMCID:: PMC3307269

Abstract Article PDF–1.9M

Select item 296416919.

Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1

Koji Kikuchi, Yohei Niikura, Katsumi Kitagawa, Akira Kikuchi

EMBO J. 2010 Oct 20; 29(20): 3470–3483. Published online 2010 Sep 7. doi: 10.1038/emboj.2010.221

PMCID:: PMC2964169

Abstract Article PDF–1.3M

Select item 285746820.

Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells

Shinji Matsumoto, Katsumi Fumoto, Tetsuji Okamoto, Kozo Kaibuchi, Akira Kikuchi

EMBO J. 2010 Apr 7; 29(7): 1192–1204. Published online 2010 Mar 11. doi: 10.1038/emboj.2010.26

PMCID:: PMC2857468

Abstract Article PDF–2.3M

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PMC Links for Gene (Select 1856) (124)
PMC
PREDICTED: Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcrip...
PREDICTED: Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X5, mRNA
gi|2217310426|ref|XM_047435522.1|

Nucleotide
segment polarity protein dishevelled homolog DVL-2 isoform X2 [Homo sapiens]
segment polarity protein dishevelled homolog DVL-2 isoform X2 [Homo sapiens]
gi|2217310421|ref|XP_047291474.1|

Protein
PREDICTED: Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcrip...
PREDICTED: Homo sapiens dishevelled segment polarity protein 2 (DVL2), transcript variant X1, mRNA
gi|2217310419|ref|XM_005256502.3|

Nucleotide

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