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Select item 108514871.

The scaffold of neutrophil extracellular traps promotes CCA progression and modulates angiogenesis via ITGAV/NFκB

Congyi Zhang, Dehai Wu, Bowen Dong, Guanqun Liao, Yang Yu, Shizhuan Huang, Feng Luo, Bin Zhang, Haotian Wu, Tianwei Li, Dixiang Wen, Sheng Tai

Cell Commun Signal. 2024; 22: 103. Published online 2024 Feb 8. doi: 10.1186/s12964-024-01500-5

PMCID:: PMC10851487

Abstract Article PDF–23M

Select item 105424462.

Transcriptomic analysis of PADI4 target genes during multi-lineage differentiation of embryonic stem cells

Anup Kumar Singh, Soumen Khan, Daniel Moore, Simon Andrews, Maria A. Christophorou

Philos Trans R Soc Lond B Biol Sci. November 20, 2023; 378(1890): 20220236. Published online October 02, 2023. doi: 10.1098/rstb.2022.0236

PMCID:: PMC10542446

Abstract Article PDF–1.4M

Select item 101516473.

The role of protein arginine deiminase 4-dependent neutrophil extracellular traps formation in ulcerative colitis

Ping Wang, Dan Liu, Ziqi Zhou, Fangjun Liu, Yiming Shen, Qi You, Shiping Lu, Jie Wu

Front Immunol. 2023; 14: 1144976. Published online 2023 Apr 18. doi: 10.3389/fimmu.2023.1144976

PMCID:: PMC10151647

Abstract Article PDF–17M

Select item 98475594.

Neutrophil inhibition improves acute inflammation in a murine model of viral myocarditis

Paolo Carai, Laura Florit González, Stijn Van Bruggen, Valerie Spalart, Daria De Giorgio, Nadéche Geuens, Kimberly Martinod, Elizabeth Anne Vincent Jones, Stephane Heymans

Cardiovasc Res. 2022 Dec; 118(17): 3331–3345. Published online 2022 Apr 15. doi: 10.1093/cvr/cvac052

PMCID:: PMC9847559

Abstract Article PDF–1.7M

Select item 95323745.

A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression

Hui Deng, Cindy Lin, Laura Garcia-Gerique, Shuyu Fu, Zachary Cruz, Erin E. Bonner, Matthew Rosenwasser, Sridharan Rajagopal, M Naveen Sadhu, Chandru Gajendran, Mohd Zainuddin, Ramachandraiah Gosu, Dhanalakshmi Sivanandhan, Miriam A. Shelef, Brian Nam, Dan T. Vogl, Dmitry I. Gabrilovich, Yulia Nefedova

Cancer Res. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Cancer Res. 2022 Oct 4; 82(19): 3561–3572. doi: 10.1158/0008-5472.CAN-21-4045

PMCID:: PMC9532374

Abstract Article PDF–1.6M

Select item 92468396.

The prominent role of hematopoietic peptidyl arginine deiminase 4 in arthritis: collagen and G-CSF induced arthritis model in C57BL/6 mice

Shoichi Fukui, Sarah Gutch, Saeko Fukui, Deya Cherpokova, Karen Aymonnier, Casey E Sheehy, Long Chu, Denisa D Wagner

Arthritis Rheumatol. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Arthritis Rheumatol. 2022 Jul; 74(7): 1139–1146. Published online 2022 Jun 7. doi: 10.1002/art.42093

PMCID:: PMC9246839

Abstract Article PDF–1.4M

Select item 90082067.

PAD4 Immunization Triggers Anti-Citrullinated Peptide Antibodies in Normal Mice: Analysis With Peptide Arrays

Marie F. Hemon, Nathalie C. Lambert, Fanny Arnoux, Jean Roudier, Isabelle Auger

Front Immunol. 2022; 13: 840035. Published online 2022 Mar 31. doi: 10.3389/fimmu.2022.840035

PMCID:: PMC9008206

Abstract Article PDF–3.8M

Select item 88014388.

Neutrophil Extracellular Traps Caused by Gut Leakage Trigger the Autoimmune Response in Nonobese Diabetic Mice

Qi You, Yiming Shen, Yiling Wu, Yuyan Li, Chang Liu, Fengjie Huang, Harvest F. Gu, Jie Wu

Front Immunol. 2021; 12: 711423. Published online 2022 Jan 17. doi: 10.3389/fimmu.2021.711423

PMCID:: PMC8801438

Abstract Article PDF–7.7M

Select item 81959839.

Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway

Shilong Sun, Zehua Duan, Xinyu Wang, Chengnan Chu, Chao Yang, Fang Chen, Daojuan Wang, Chenyang Wang, Qiurong Li, Weiwei Ding

Cell Death Dis. 2021 Jun; 12(6): 606. Published online 2021 Jun 11. doi: 10.1038/s41419-021-03896-1

PMCID:: PMC8195983

Abstract Article PDF–4.1M

Select item 819043510.

TcpC inhibits neutrophil extracellular trap formation by enhancing ubiquitination mediated degradation of peptidylarginine deiminase 4

Qian Ou, Jia-qi Fang, Zhe-sheng Zhang, Zhe Chi, Jie Fang, Di-yan Xu, Kai-zhong Lu, Meng-qing Qian, Da-yong Zhang, Jun-ping Guo, Wei Gao, Na-ru Zhang, Jian-ping Pan

Nat Commun. 2021; 12: 3481. Published online 2021 Jun 9. doi: 10.1038/s41467-021-23881-8

PMCID:: PMC8190435

Abstract Article PDF–6.4M

Select item 812823511.

Neutrophil stimulation with citrullinated histone H4 slows down calcium influx and reduces NET formation compared with native histone H4

Lai Shi, Karen Aymonnier, Denisa D. Wagner

PLoS One. 2021; 16(5): e0251726. Published online 2021 May 17. doi: 10.1371/journal.pone.0251726

PMCID:: PMC8128235

Abstract Article PDF–2.3M

Select item 723750212.

Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke

Lijing Kang, Huilin Yu, Xing Yang, Yuanbo Zhu, Xiaofei Bai, Ranran Wang, Yongliang Cao, Haochen Xu, Haiyu Luo, Lu Lu, Mei-Juan Shi, Yujing Tian, Wenying Fan, Bing-Qiao Zhao

Nat Commun. 2020; 11: 2488. Published online 2020 May 19. doi: 10.1038/s41467-020-16191-y

PMCID:: PMC7237502

Abstract Article PDF–6.1M

Select item 682558813.

Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth

Hamza O. Yazdani, Eva Roy, Alexander J. Comerci, Dirk J. van der Windt, Hongji Zhang, Hai Huang, Patricia Loughran, Sruti Shiva, David A. Geller, David L. Bartlett, Allan Tsung, Tai Sheng, Richard L. Simmons, Samer Tohme

Cancer Res. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Res. 2019 Nov 1; 79(21): 5626–5639. Published online 2019 Sep 13. doi: 10.1158/0008-5472.CAN-19-0800

PMCID:: PMC6825588

Abstract Article PDF–3.7M

Select item 677980614.

Compromised Anti-inflammatory Action of Neutrophil Extracellular Traps in PAD4-Deficient Mice Contributes to Aggravated Acute Inflammation After Myocardial Infarction

Kaveh Eghbalzadeh, Leena Georgi, Theresa Louis, Haizhi Zhao, Ugur Keser, Carolyn Weber, Martin Mollenhauer, Andreas Conforti, Thorsten Wahlers, Adnana Paunel-Görgülü

Front Immunol. 2019; 10: 2313. Published online 2019 Oct 1. doi: 10.3389/fimmu.2019.02313

PMCID:: PMC6779806

Abstract Article PDF–2.5M

Select item 642887915.

Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia

José Perdomo, Halina H. L. Leung, Zohra Ahmadi, Feng Yan, James J. H. Chong, Freda H. Passam, Beng H. Chong

Nat Commun. 2019; 10: 1322. Published online 2019 Mar 21. doi: 10.1038/s41467-019-09160-7

PMCID:: PMC6428879

Abstract Article PDF–4.7M

Select item 631453416.

Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

WonJae Lee, Song Yi Ko, Muhaned S. Mohamed, Hilary A. Kenny, Ernst Lengyel, Honami Naora

J Exp Med. 2019 Jan 7; 216(1): 176–194. doi: 10.1084/jem.20181170

PMCID:: PMC6314534

Abstract Article PDF–3.8M

Select item 623723317.

Neutrophil accumulation and NET release contribute to thrombosis in HIT

Kandace Gollomp, Minna Kim, Ian Johnston, Vincent Hayes, John Welsh, Gowthami M. Arepally, Mark Kahn, Michele P. Lambert, Adam Cuker, Douglas B. Cines, Lubica Rauova, M. Anna Kowalska, Mortimer Poncz

JCI Insight. 2018 Sep 20; 3(18): e99445. Published online 2018 Sep 20. doi: 10.1172/jci.insight.99445

PMCID:: PMC6237233

Abstract Article PDF–5.3M

Select item 607461218.

Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4)

T. J. Hollingsworth, Marko Z. Radic, Sarka Beranova-Giorgianni, Francesco Giorgianni, Yanming Wang, Alessandro Iannaccone

Invest Ophthalmol Vis Sci. 2018 Aug; 59(10): 3808–3815. doi: 10.1167/iovs.18-24118

PMCID:: PMC6074612

Abstract Article PDF–899K

Select item 579457319.

Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury

Wesley M. Raup-Konsavage, Yanming Wang, Wei Wei Wang, Denis Feliers, Hong Ruan, W. Brian Reeves

Kidney Int. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Kidney Int. 2018 Feb; 93(2): 365–374. Published online 2017 Oct 20. doi: 10.1016/j.kint.2017.08.014

PMCID:: PMC5794573

Abstract Article PDF–1.6M

Select item 534573520.

Platelets and neutrophil extracellular traps collaborate to promote intravascular coagulation during sepsis in mice

Braedon McDonald, Rachelle P. Davis, Seok-Joo Kim, Mandy Tse, Charles T. Esmon, Elzbieta Kolaczkowska, Craig N. Jenne

Blood. 2017 Mar 9; 129(10): 1357–1367. Prepublished online 2017 Jan 10. doi: 10.1182/blood-2016-09-741298

Correction in:: Blood. 2022 Feb 10; 139(6): 952.

PMCID:: PMC5345735

Abstract Article

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PMC Links for Gene (Select 18602) (103)
PMC
SH3 domain-containing protein [Bacillus subtilis]
SH3 domain-containing protein [Bacillus subtilis]
gi|2557549238|gnl|PRJNA924944|PIB33 0|gb|WLD62617.1|

Protein
aa68h04.s1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:826135 3', mRNA sequence
aa68h04.s1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:826135 3', mRNA sequence
gi|2261889|gnl|dbEST|1165986|gb|AA5 .1|

Nucleotide
hypothetical protein [Bacillus sp. SN1]
hypothetical protein [Bacillus sp. SN1]
gi|1280952318|ref|WP_100275653.1|

Protein
poly(A) RNA polymerase GLD2 isoform 2 [Homo sapiens]
poly(A) RNA polymerase GLD2 isoform 2 [Homo sapiens]
gi|1917203315|ref|NP_001375050.1|

Protein

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