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Select item 99141071.

Endothelial Specific Deletion of Autotaxin Improves Stroke Outcomes

Susmita Bhattarai, Utsab Subedi, Shrivats Manikandan, Sudha Sharma, Papori Sharma, Chloe Miller, Md Shenuarin Bhuiyan, Srivatsan Kidambi, Vassilis Aidinis, Hong Sun, Sumitra Miriyala, Manikandan Panchatcharam

Cells. 2023 Feb; 12(3): 511. Published online 2023 Feb 3. doi: 10.3390/cells12030511

PMCID:: PMC9914107

Abstract Article PDF–3.5M

Select item 68173752.

Osteoclast-derived Autotaxin, a distinguishing factor for inflammatory bone loss

Sacha FLAMMIER, Olivier PEYRUCHAUD, Fanny BOURGUILLAULT, François DUBOEUF, Jean-Luc DAVIGNON, Derek D NORMAN, Sylvie ISAAC, Hubert MAROTTE, Gabor TIGYI, Irma MACHUCA-GAYET, Fabienne COURY

Arthritis Rheumatol. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Arthritis Rheumatol. 2019 Nov; 71(11): 1801–1811. Published online 2019 Sep 30. doi: 10.1002/art.41005

PMCID:: PMC6817375

Abstract Article

Select item 64045653.

Autotaxin determines colitis severity in mice and is secreted by B cells in the colon

Songbai Lin, Abedul Haque, Reben Raeman, Leilei Guo, Peijian He, Timothy L. Denning, Bassel El-Rayes, Wouter H. Moolenaar, C. Chris Yun

FASEB J. 2019 Mar; 33(3): 3623–3635. Published online 2018 Nov 27. doi: 10.1096/fj.201801415RR

PMCID:: PMC6404565

Abstract Article

Select item 63668704.

Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity

J. Anthony Brandon, Maria Kraemer, Julia Vandra, Suchismita Halder, Margo Ubele, Andrew J. Morris, Susan S. Smyth

PLoS One. 2019; 14(2): e0208099. Published online 2019 Feb 7. doi: 10.1371/journal.pone.0208099

PMCID:: PMC6366870

Abstract Article PDF–3.1M

Select item 61683045.

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

Kenneth D’Souza, Carine Nzirorera, Andrew M. Cowie, Geena P. Varghese, Purvi Trivedi, Thomas O. Eichmann, Dipsikha Biswas, Mohamed Touaibia, Andrew J. Morris, Vassilis Aidinis, Daniel A. Kane, Thomas Pulinilkunnil, Petra C. Kienesberger

J Lipid Res. 2018 Oct; 59(10): 1805–1817. Published online 2018 Aug 2. doi: 10.1194/jlr.M082008

PMCID:: PMC6168304

Abstract Article PDF–1.7M

Select item 58568376.

Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay

Ryunosuke Ohkawa, Makoto Kurano, Noboru Sakai, Tatsuya Kishimoto, Takahiro Nojiri, Koji Igarashi, Shigemi Hosogaya, Yukio Ozaki, Tomotaka Dohi, Katsumi Miyauchi, Hiroyuki Daida, Junken Aoki, Shigeo Okubo, Hitoshi Ikeda, Minoru Tozuka, Yutaka Yatomi

Sci Rep. 2018; 8: 4725. Published online 2018 Mar 16. doi: 10.1038/s41598-018-23009-x

PMCID:: PMC5856837

Abstract Article PDF–1.7M

Select item 50986537.

Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program

Cody Kime, Masayo Sakaki-Yumoto, Leeanne Goodrich, Yohei Hayashi, Salma Sami, Rik Derynck, Michio Asahi, Barbara Panning, Shinya Yamanaka, Kiichiro Tomoda

Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): 12478–12483. Published online 2016 Oct 13. doi: 10.1073/pnas.1608564113

PMCID:: PMC5098653

Abstract Article PDF–1.2M

Select item 48717978.

Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis

Katharine E. Black, Evgeny Berdyshev, Gretchen Bain, Flavia V. Castelino, Barry S. Shea, Clemens K. Probst, Benjamin A. Fontaine, Irina Bronova, Lance Goulet, David Lagares, Neil Ahluwalia, Rachel S. Knipe, Viswanathan Natarajan, Andrew M. Tager

FASEB J. 2016 Jun; 30(6): 2435–2450. Published online 2016 Mar 22. doi: 10.1096/fj.201500197R

PMCID:: PMC4871797

Abstract Article

Select item 44380009.

Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects

Hiroshi Yukiura, Kuniyuki Kano, Ryoji Kise, Asuka Inoue, Junken Aoki

PLoS One. 2015; 10(5): e0126734. Published online 2015 May 19. doi: 10.1371/journal.pone.0126734

PMCID:: PMC4438000

Abstract Article PDF–2.5M

Select item 427530310.

AUTOTAXIN DOWNREGULATES LPS – INDUCED MICROGLIA ACTIVATION AND PRO-INFLAMMATORY CYTOKINES PRODUCTION

Rana Awada, Jean Sébastien Saulnier-Blache, Sandra Grès, Emmanuel Bourdon, Philippe Rondeau, Avinash Parimisetty, Ruben Orihuela, G. Jean Harry, Christian Lefebvre d’Hellencourt

J Cell Biochem. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: J Cell Biochem. 2014 Dec; 115(12): 2123–2132. doi: 10.1002/jcb.24889

PMCID:: PMC4275303

Abstract Article PDF–1.3M

Select item 372363611.

Autotaxin Signaling Governs Phenotypic Heterogeneity in Visceral and Parietal Mesothelia

Elaine L. Shelton, Cristi L. Galindo, Charles H. Williams, Elise Pfaltzgraff, Charles C. Hong, David M. Bader

PLoS One. 2013; 8(7): e69712. Published online 2013 Jul 25. doi: 10.1371/journal.pone.0069712

PMCID:: PMC3723636

Abstract Article PDF–2.2M

Select item 309024512.

Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid

Rodolphe Dusaulcy, Chloé Rancoule, Sandra Grès, Estelle Wanecq, André Colom, Charlotte Guigné, Laurens A. van Meeteren, Wouter H. Moolenaar, Philippe Valet, Jean Sébastien Saulnier-Blache

J Lipid Res. 2011 Jun; 52(6): 1247–1255. doi: 10.1194/jlr.M014985

PMCID:: PMC3090245

Abstract Article PDF–1.0M

Select item 284003013.

Cancer Cell Expression of Autotaxin Controls Bone Metastasis Formation in Mouse through Lysophosphatidic Acid-Dependent Activation of Osteoclasts

Marion David, Estelle Wannecq, Françoise Descotes, Silvia Jansen, Blandine Deux, Johnny Ribeiro, Claire-Marie Serre, Sandra Grès, Nathalie Bendriss-Vermare, Mathieu Bollen, Simone Saez, Junken Aoki, Jean-Sébastien Saulnier-Blache, Philippe Clézardin, Olivier Peyruchaud

PLoS One. 2010; 5(3): e9741. Published online 2010 Mar 17. doi: 10.1371/journal.pone.0009741

PMCID:: PMC2840030

Abstract Article PDF–4.3M

Select item 265226914.

Autotaxin/Lysopholipase D and Lysophosphatidic Acid Regulate Murine Hemostasis and Thrombosis

Zehra Pamuklar, Lorenzo Federico, Shuying Liu, Makiko Umezu-Goto, Anping Dong, Manikandan Panchatcharam, Zachary Fulerson, Evgeny Berdyshev, Viswanathan Natarajan, Xianjun Fang, Laurens A. van Meeteren, Wouter H. Moolenaar, Gordon B. Mills, Andrew J. Morris, Susan S. Smyth

J Biol Chem. 2009 Mar 13; 284(11): 7385–7394. doi: 10.1074/jbc.M807820200

Correction in:: J Biol Chem. 2009 Jul 31; 284(31): 21100.

PMCID:: PMC2652269

Abstract Article PDF–576K

Select item 227739215.

Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

Makoto Inoue, Lin Ma, Junken Aoki, Jerold Chun, Hiroshi Ueda

Mol Pain. 2008; 4: 6. Published online 2008 Feb 8. doi: 10.1186/1744-8069-4-6

PMCID:: PMC2277392

Abstract Article PDF–394K

Select item 1107301316.

NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment

Yutong Miao, Yang Zhao, Lulu Han, Xiaolong Ma, Jiacheng Deng, Juan Yang, Silin Lü, Fangyu Shao, Wei Kong, Wengong Wang, Qingbo Xu, Xian Wang, Juan Feng

Cell Mol Life Sci. 2021 Feb; 78(4): 1709–1727. Published online 2020 Jul 30. doi: 10.1007/s00018-020-03607-7

PMCID:: PMC11073013

Abstract Article PDF–2.5M

Select item 1079242717.

Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling

Anna Janovicz, Aliz Majer, Mónika Kosztelnik, Miklós Geiszt, Jerold Chun, Satoshi Ishii, Gábor József Tigyi, Zoltán Benyó, Éva Ruisanchez

Exp Biol Med (Maywood) 2023 Oct; 248(20): 1887–1894. Published online 2023 Oct 14. doi: 10.1177/15353702231199081

PMCID:: PMC10792427

Abstract Article PDF–1.0M

Select item 839517418.

Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model

Lisha Joshi, Ioanna Plastira, Eva Bernhart, Helga Reicher, Alexander Triebl, Harald C. Köfeler, Wolfgang Sattler

Int J Mol Sci. 2021 Aug; 22(16): 8519. Published online 2021 Aug 7. doi: 10.3390/ijms22168519

PMCID:: PMC8395174

Abstract Article PDF–3.4M

Select item 711766919.

Genetic deletion of Autotaxin from CD11b⁺ cells decreases the severity of experimental autoimmune encephalomyelitis

Ioanna Ninou, Ioanna Sevastou, Christiana Magkrioti, Eleanna Kaffe, George Stamatakis, Spyros Thivaios, George Panayotou, Junken Aoki, George Kollias, Vassilis Aidinis

PLoS One. 2020; 15(4): e0226050. Published online 2020 Apr 2. doi: 10.1371/journal.pone.0226050