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Select item 80184351.

Protein kinase C-θ knockout decreases serum IL-10 levels and inhibits insulin secretion from islet β cells

Feng Hong, Yang Yang, Baiyi Chen, Peng Li, Guoguang Wang, Yuxin Jiang

Islets. 2021; 13(1-2): 24–31. Published online 2021 Mar 9. doi: 10.1080/19382014.2021.1890963

PMCID:: PMC8018435

Abstract Article PDF–1.3M

Select item 71778082.

Targeting PKCθ Promotes Satellite Cell Self-Renewal

Anna Benedetti, Piera Filomena Fiore, Luca Madaro, Biliana Lozanoska-Ochser, Marina Bouché

Int J Mol Sci. 2020 Apr; 21(7): 2419. Published online 2020 Mar 31. doi: 10.3390/ijms21072419

PMCID:: PMC7177808

Abstract Article PDF–3.1M

Select item 69887323.

Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)

Ghazi M. Rahman, Sreejesh Shanker, Nancy E. Lewin, Noemi Kedei, Colin S. Hill, B. V. Venkataram Prasad, Peter M. Blumberg, Joydip Das

Biochem J. Author manuscript; available in PMC 2020 Jan 29.

Published in final edited form as: Biochem J. 2013 Apr 1; 451(1): 33–44. doi: 10.1042/BJ20121307

PMCID:: PMC6988732

Abstract Article PDF–2.1M

Select item 67293394.

The Role of the Theta Isoform of Protein Kinase C (PKC) in Activity-Dependent Synapse Elimination: Evidence from the PKC Theta Knock-Out Mouse In Vivo and In Vitro

Min-Xu Li, Min Jia, Li-Xia Yang, Hao Jiang, Maria A. Lanuza, Carmen M. Gonzalez, Phillip G. Nelson

J Neurosci. 2004 Apr 14; 24(15): 3762–3769. doi: 10.1523/JNEUROSCI.3930-03.2004

PMCID:: PMC6729339

Abstract Article PDF–465K

Select item 54396645.

Protein kinase C theta is dispensable for suppression mediated by CD25⁺CD4⁺ regulatory T cells

Kerstin Siegmund, Nikolaus Thuille, Katarzyna Wachowicz, Natascha Hermann-Kleiter, Gottfried Baier

PLoS One. 2017; 12(5): e0175463. Published online 2017 May 22. doi: 10.1371/journal.pone.0175463

PMCID:: PMC5439664

Abstract Article PDF–3.0M

Select item 53108406.

PKCθ links proximal T cell and Notch signaling through localized regulation of the actin cytoskeleton

Graham J Britton, Rachel Ambler, Danielle J Clark, Elaine V Hill, Helen M Tunbridge, Kerrie E McNally, Bronwen R Burton, Philomena Butterweck, Catherine Sabatos-Peyton, Lea A Hampton-O’Neil, Paul Verkade, Christoph Wülfing, David Cameron Wraith

eLife. 2017; 6: e20003. Published online 2017 Jan 31. doi: 10.7554/eLife.20003

PMCID:: PMC5310840

Abstract Article PDF–5.2M

Select item 52915377.

Protein kinase C theta is required for efficient induction of IL-10-secreting T cells

Graham J. Britton, Ruth E. Mitchell, Bronwen R. Burton, David C. Wraith

PLoS One. 2017; 12(2): e0171547. Published online 2017 Feb 3. doi: 10.1371/journal.pone.0171547

PMCID:: PMC5291537

Abstract Article PDF–2.6M

Select item 51133148.

Anatomical and Gene Expression Changes in the Retinal Pigmented Epithelium Atrophy 1 (rpea1) Mouse: A Potential Model of Serous Retinal Detachment

Gabriel Luna, Geoffrey P. Lewis, Kenneth A. Linberg, Bo Chang, Quiri Hu, Peter J. Munson, Arvydas Maminishkis, Sheldon S. Miller, Steven K. Fisher

Invest Ophthalmol Vis Sci. 2016 Sep; 57(11): 4641–4654. Published online 2016 Sep 7. doi: 10.1167/iovs.15-19044

PMCID:: PMC5113314

Abstract Article PDF–2.8M

Select item 42438649.

Inhibition of PKC-θ preserves cardiac function and reduces fibrosis in streptozotocin-induced diabetic cardiomyopathy

Zhao Li, Chowdhury S Abdullah, Zhu-Qiu Jin

Br J Pharmacol. 2014 Jun; 171(11): 2913–2924. Published online 2014 May 15. doi: 10.1111/bph.12621

PMCID:: PMC4243864

Abstract Article PDF–2.6M

Select item 400850310.

Protein Kinase C θ Regulates the Phenotype of Murine CD4⁺ Th17 Cells

Katarzyna Wachowicz, Natascha Hermann-Kleiter, Marlies Meisel, Kerstin Siegmund, Nikolaus Thuille, Gottfried Baier

PLoS One. 2014; 9(5): e96401. Published online 2014 May 2. doi: 10.1371/journal.pone.0096401

PMCID:: PMC4008503

Abstract Article PDF–1.5M

Select item 327454511.

Ameliorated ConA-Induced Hepatitis in the Absence of PKC-theta

Xianfeng Fang, Ruiqing Wang, Jian Ma, Yan Ding, Weirong Shang, Zuoming Sun

PLoS One. 2012; 7(2): e31174. Published online 2012 Feb 7. doi: 10.1371/journal.pone.0031174

PMCID:: PMC3274545

Abstract Article PDF–1.7M

Select item 317227212.

An active kinase domain is required for retention of PKCθ at the T cell immunological synapse

Natalia G. Cartwright, Anuj K. Kashyap, Brian C. Schaefer

Mol Biol Cell. 2011 Sep 15; 22(18): 3491–3497. doi: 10.1091/mbc.E10-11-0916

PMCID:: PMC3172272

Abstract Article PDF–2.4M

Select item 306981913.

Protein Kinase C-Theta Is Required for Development of Experimental Cerebral Malaria

Mathilde Fauconnier, Marie-Laure Bourigault, Sandra Meme, Frederic Szeremeta, Jennifer Palomo, Adeline Danneels, Sabine Charron, Lizette Fick, Muazzam Jacobs, Jean-Claude Beloeil, Bernhard Ryffel, Valerie F.J. Quesniaux

Am J Pathol. 2011 Jan; 178(1): 212–221. doi: 10.1016/j.ajpath.2010.11.008

PMCID:: PMC3069819

Abstract Article PDF–1.6M

Select item 303231314.

Protein kinase Cθ is required for cardiomyocyte survival and cardiac remodeling

R Paoletti, A Maffei, L Madaro, A Notte, E Stanganello, G Cifelli, P Carullo, M Molinaro, G Lembo, M Bouché

Cell Death Dis. 2010 May; 1(5): e45. Published online 2010 May 27. doi: 10.1038/cddis.2010.24

PMCID:: PMC3032313

Abstract Article PDF–662K

Select item 295034615.

Protein Kinase C θ Deficiency Increases Resistance of C57BL/6J Mice to Plasmodium berghei Infection-Induced Cerebral Malaria

Ariel Ohayon, Jacob Golenser, Rosa Sinay, Ami Tamir, Amnon Altman, Yaakov Pollack, Noah Isakov

Infect Immun. 2010 Oct; 78(10): 4195–4205. Published online 2010 Jul 26. doi: 10.1128/IAI.00465-10

PMCID:: PMC2950346

Abstract Article PDF–3.3M

Select item 293720916.

PKCθ is necessary for efficient activation of NFκB, NFAT, and AP-1 during positive selection of thymocytes

Thomas Gruber, Christa Pfeifhofer-Obermair, Gottfried Baier

Immunol Lett. 2010 Aug 16; 132(1-2): 6–11. doi: 10.1016/j.imlet.2010.04.008

PMCID:: PMC2937209

Abstract Article

Select item 291626117.

Protective Toxoplasma gondii-Specific T-Cell Responses Require T-Cell-Specific Expression of Protein Kinase C-Theta

Gopala Nishanth, Monika Sakowicz-Burkiewicz, Ulrike Händel, Stefanie Kliche, Xiaoqian Wang, Michael Naumann, Martina Deckert, Dirk Schlüter

Infect Immun. 2010 Aug; 78(8): 3454–3464. Published online 2010 May 24. doi: 10.1128/IAI.01407-09

PMCID:: PMC2916261

Abstract Article PDF–1.7M

Select item 288839718.

Protein Kinase Cθ Negatively Regulates Store-independent Ca²⁺ Entry and Phosphatidylserine Exposure Downstream of Glycoprotein VI in Platelets

Matthew T. Harper, Alastair W. Poole

J Biol Chem. 2010 Jun 25; 285(26): 19865–19873. Published online 2010 Apr 13. doi: 10.1074/jbc.M109.085654

PMCID:: PMC2888397

Abstract Article PDF–1.4M

Select item 273591719.

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents

Stephen C. Benoit, Christopher J. Kemp, Carol F. Elias, William Abplanalp, James P. Herman, Stephanie Migrenne, Anne-Laure Lefevre, Céline Cruciani-Guglielmacci, Christophe Magnan, Fang Yu, Kevin Niswender, Boman G. Irani, William L. Holland, Deborah J. Clegg

J Clin Invest. 2009 Sep 1; 119(9): 2577–2589. Published online 2009 Aug 10. doi: 10.1172/JCI36714