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Select item 34543441.

In Vitro Phosphorylation and Acetylation of the Murine Pocket Protein Rb2/p130

Muhammad Saeed, Florian Schwarze, Adele Loidl, Joachim Meraner, Markus Lechner, Peter Loidl

PLoS One. 2012; 7(9): e46174. Published online 2012 Sep 24. doi: 10.1371/journal.pone.0046174

PMCID:: PMC3454344

Abstract Article PDF–1.0M

Select item 29904062.

A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

Roberta Benetti, Susana Gonzalo, Isabel Jaco, Purificación Muñoz, Susana Gonzalez, Stefan Schoeftner, Elizabeth Murchison, Thomas Andl, Taiping Chen, Peter Klatt, En Li, Manuel Serrano, Sarah Millar, Gregory Hannon, Maria A Blasco

Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Nov 23.

Published in final edited form as: Nat Struct Mol Biol. 2008 Mar; 15(3): 268–279. Published online 2008 Mar 2. doi: 10.1038/nsmb.1399

Correction in:: volume 15 on page 998

PMCID:: PMC2990406

Abstract Article PDF–3.2M

Select item 22685553.

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130

Qiang Wang, Yan Chun Li, Jinhua Wang, Juan Kong, Yuchen Qi, Richard J. Quigg, Xinmin Li

Proc Natl Acad Sci U S A. 2008 Feb 26; 105(8): 2889–2894. Published online 2008 Feb 19. doi: 10.1073/pnas.0800178105

PMCID:: PMC2268555

Abstract Article PDF–1.0M

Select item 42620664.

Altered Signaling in the G1 Phase Deregulates Chondrocyte Growth in a Mouse Model With Proteoglycan Undersulfation

Fabio De Leonardis, Luca Monti, Benedetta Gualeni, Ruggero Tenni, Antonella Forlino, Antonio Rossi

J Cell Biochem. 2014 Oct; 115(10): 1779–1786. Published online 2014 May 13. doi: 10.1002/jcb.24844

PMCID:: PMC4262066

Abstract Article PDF–240K

Select item 40542845.

Loss of the Mammalian DREAM Complex Deregulates Chondrocyte Proliferation

Chantal Forristal, Shauna A. Henley, James I. MacDonald, Jason R. Bush, Carley Ort, Daniel T. Passos, Srikanth Talluri, Charles A. Ishak, Michael J. Thwaites, Chris J. Norley, Larisa Litovchick, James A. DeCaprio, Gabriel DiMattia, David W. Holdsworth, Frank Beier, Frederick A. Dick

Mol Cell Biol. 2014 Jun; 34(12): 2221–2234. doi: 10.1128/MCB.01523-13

PMCID:: PMC4054284

Abstract Article PDF–2.2M

Select item 31321026.

Mature Mice Lacking Rbl2/p130 Gene Have Supernumerary Inner Ear Hair Cells and Supporting Cells

Sonia M. Rocha-Sanchez, Laura R. Scheetz, Melissa Contreras, Michael D. Weston, Megan Korte, JoAnn McGee, Edward J. Walsh

J Neurosci. 2011 Jun 15; 31(24): 8883–8893. doi: 10.1523/JNEUROSCI.5821-10.2011

PMCID:: PMC3132102

Abstract Article PDF–3.6M

Select item 21740077.

FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest

Emmanuel Laplantine, Ferdinand Rossi, Malika Sahni, Claudio Basilico, David Cobrinik

J Cell Biol. 2002 Aug 19; 158(4): 741–750. doi: 10.1083/jcb.200205025

PMCID:: PMC2174007

Abstract Article PDF–453K

Select item 15927878.

p27^Kip1 and p130 Cooperate To Regulate Hematopoietic Cell Proliferation In Vivo

Inês Soeiro, Azim Mohamedali, Hanna M. Romanska, Nicholas C. Lea, Emma S. Child, Janet Glassford, Stephen J. Orr, Claudia Roberts, Kikkeri N. Naresh, El-Nasir Lalani, David J. Mann, Roger J. Watson, N. Shaun B. Thomas, Eric W.-F. Lam

Mol Cell Biol. 2006 Aug; 26(16): 6170–6184. doi: 10.1128/MCB.02182-05

PMCID:: PMC1592787

Abstract Article PDF–3.3M

Select item 10616089.

Overlapping Roles of Pocket Proteins in the Myocardium Are Unmasked by Germ Line Deletion of p130 plus Heart-Specific Deletion of Rb

W. R. MacLellan, A. Garcia, H. Oh, P. Frenkel, M. C. Jordan, K. P. Roos, M. D. Schneider

Mol Cell Biol. 2005 Mar; 25(6): 2486–2497. doi: 10.1128/MCB.25.6.2486-2497.2005

PMCID:: PMC1061608

Abstract Article PDF–896K

Select item 12147810.

p130 Is Dispensable in Peripheral T Lymphocytes: Evidence for Functional Compensation by p107 and pRB

George J. Mulligan, James Wong, Tyler Jacks

Mol Cell Biol. 1998 Jan; 18(1): 206–220. doi: 10.1128/mcb.18.1.206

PMCID:: PMC121478

Abstract Article PDF–2.0M

Select item 727707511.

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-Tumor Immunity in Small Cell Lung Cancer

Hua Zhang, Camilla L. Christensen, Ruben Dries, Matthew G. Oser, Jiehui Deng, Brian Diskin, Fei Li, Yuanwang Pan, Xuzhu Zhang, Yandong Yin, Eleni Papadopoulos, Val Pyon, Cassandra Thakurdin, Nicholas Kwiatkowski, Kandarp Jani, Alexandra R. Rabin, Dayanne M Castro, Ting Chen, Heather Silver, Qingyuan Huang, Mirna Bulatovic, Catríona M. Dowling, Belen Sundberg, Alan Leggett, Michela Ranieri, Han Han, Shuai Li, Annan Yang, Kristen E. Labbe, Christina Almonte, Vladislav O. Sviderskiy, Max Quinn, Jack Donaghue, Eric S. Wang, Tinghu Zhang, Zhixiang He, Vamsidhar Velcheti, Peter S. Hammerman, Gordon J. Freeman, Richard Bonneau, William G. Kaelin, Jr, Kate D. Sutherland, Ariena Kersbergen, Andrew J. Aguirre, Guo-Cheng Yuan, Eli Rothenberg, George Miller, Nathanael S. Gray, Kwok-Kin Wong

Cancer Cell. Author manuscript; available in PMC 2021 Jan 13.

Published in final edited form as: Cancer Cell. 2020 Jan 13; 37(1): 37–54.e9. Published online 2019 Dec 26. doi: 10.1016/j.ccell.2019.11.003

PMCID:: PMC7277075

Abstract Article PDF–3.2M

Select item 656383412.

Targeting DNA damage response promotes anti-tumor immunity through STING-mediated T-cell activation in small cell lung cancer

Triparna Sen, B. Leticia Rodriguez, Limo Chen, Carminia Della Corte, Naoto Morikawa, Junya Fujimoto, Sandra Cristea, Thuyen Nguyen, Lixia Diao, Lerong Li, Youhong Fan, Yongbin Yang, Jing Wang, Bonnie S. Glisson, Ignacio I. Wistuba, Julien Sage, John V. Heymach, Don L. Gibbons, Lauren A. Byers

Cancer Discov. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Discov. 2019 May; 9(5): 646–661. Published online 2019 Feb 18. doi: 10.1158/2159-8290.CD-18-1020

PMCID:: PMC6563834

Abstract Article PDF–1.5M

Select item 556385413.

CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib

Triparna Sen, Pan Tong, C. Allison Stewart, Sandra Cristea, Aly Valliani, David S. Shames, Abena B. Redwood, You Hong Fan, Lerong Li, Bonnie S. Glisson, John D. Minna, Julien Sage, Don L. Gibbons, Helen Piwnica-Worms, John V. Heymach, Jing Wang, Lauren Averett Byers

Cancer Res. Author manuscript; available in PMC 2017 Aug 21.

Published in final edited form as: Cancer Res. 2017 Jul 15; 77(14): 3870–3884. Published online 2017 May 10. doi: 10.1158/0008-5472.CAN-16-3409

PMCID:: PMC5563854

Abstract Article PDF–2.2M

Select item 535483914.

Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

Sara Lázaro, Miriam Pérez-Crespo, Ana Belén Enguita, Pilar Hernández, Jesús Martínez-Palacio, Marta Oteo, Julien Sage, Jesús M. Paramio, Mirentxu Santos

Oncotarget. 2017 Jan 17; 8(3): 4373–4386. Published online 2016 Dec 10. doi: 10.18632/oncotarget.13875

Correction in:: Oncotarget. 2017 Jul 25; 8(30): 50323.

PMCID:: PMC5354839

Abstract Article PDF–16M

Select item 414029515.

Regulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes

Grace O. Iyirhiaro, Yi Zhang, Carmen Estey, Michael J. O'Hare, Farzaneh Safarpour, Mohammad Parsanejad, Suzi Wang, Elizabeth Abdel-Messih, Steve M. Callaghan, Matthew J. During, Ruth S. Slack, David S. Park

J Biol Chem. 2014 Jun 27; 289(26): 18202–18213. Published online 2014 May 14. doi: 10.1074/jbc.M114.574145

PMCID:: PMC4140295

Abstract Article PDF–1.5M

Select item 386457116.

A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors

Nadine S Jahchan, Joel T Dudley, Pawel K Mazur, Natasha Flores, Dian Yang, Alec Palmerton, Anne-Flore Zmoos, Dedeepya Vaka, Kim QT Tran, Margaret Zhou, Karolina Krasinska, Jonathan W Riess, Joel W Neal, Purvesh Khatri, Kwon S Park, Atul J Butte, Julien Sage

Cancer Discov. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Cancer Discov. 2013 Dec; 3(12): 10.1158/2159-8290.CD-13-0183. Published online 2013 Sep 26. doi: 10.1158/2159-8290.CD-13-0183

PMCID:: PMC3864571

Abstract Article PDF–2.5M

Select item 377022417.

Animal models in retinoblastoma research

Rohini M. Nair, Swathi Kaliki, Geeta K. Vemuganti

Saudi J Ophthalmol. 2013 Jul; 27(3): 141–146. Published online 2013 Jul 4. doi: 10.1016/j.sjopt.2013.06.008

PMCID:: PMC3770224

Abstract Article PDF–746K

Select item 347312018.

Inactivating all three Rb family pocket proteins is insufficient to initiate cervical cancer

Myeong-Kyun Shin, Julien Sage, Paul F. Lambert

Cancer Res. Author manuscript; available in PMC 2013 Oct 15.

Published in final edited form as: Cancer Res. 2012 Oct 15; 72(20): 5418–5427. Published online 2012 Aug 31. doi: 10.1158/0008-5472.CAN-12-2083

PMCID:: PMC3473120

Abstract Article PDF–3.2M

Select item 329399619.

Pocket Proteins Suppress Head and Neck Cancer

Myeong-Kyun Shin, Henry C. Pitot, Paul F. Lambert

Cancer Res. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Cancer Res. 2012 Mar 1; 72(5): 1280–1289. Published online 2012 Jan 11. doi: 10.1158/0008-5472.CAN-11-2833

PMCID:: PMC3293996

Abstract Article PDF–1.7M

Select item 328059620.

Induction of Wnt/β-Catenin Signaling in Mouse Mesenchymal Stem Cells Is Associated with Activation of the p130 and E2f4 and Formation of the p130/Gsk3β/β-Catenin Complex

Nikolay Petrov, Olga Zhidkova, Vladimir Serikov, Valery Zenin, Boris Popov

Stem Cells Dev. 2012 Mar 1; 21(4): 589–597. Published online 2011 Jun 1. doi: 10.1089/scd.2011.0048

PMCID:: PMC3280596

Abstract Article PDF–736K

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PMC Links for Gene (Select 19651) (112)
PMC
PREDICTED: Mus musculus AKT interacting protein (Aktip), transcript variant X13,...
PREDICTED: Mus musculus AKT interacting protein (Aktip), transcript variant X13, mRNA
gi|1907187280|ref|XM_006530673.5|

Nucleotide
structural protein [Human astrovirus]
structural protein [Human astrovirus]
gi|367465400|gb|AEX15491.1|

Protein
RecName: Full=Retinoblastoma-like protein 2; AltName: Full=130 kDa retinoblastom...
RecName: Full=Retinoblastoma-like protein 2; AltName: Full=130 kDa retinoblastoma-associated protein; Short=p130; AltName: Full=Retinoblastoma-related protein 2; Short=RBR-2; AltName: Full=pRb2
gi|341942165|sp|Q64700.3|RBL2_MOUSE

Protein
RecName: Full=Capsid polyprotein VP90; Contains: RecName: Full=Capsid polyprotei...
RecName: Full=Capsid polyprotein VP90; Contains: RecName: Full=Capsid polyprotein VP70; Contains: RecName: Full=Core protein VP34; Contains: RecName: Full=Spike protein VP27; Contains: RecName: Full=Spike protein VP25
gi|81920401|sp|O12792.1|CAPSD_HASV1

Protein

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