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Select item 111597311.

Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer

Hideki Kataoka, Hisaki Igarashi, Masao Kanamori, Megumi Ihara, Jian‐Dong Wang, You‐Jie Wang, Zhong‐You Li, Takahiro Shimamura, Toshihiko Kobayashi, Keiji Maruyama, Toshio Nakamura, Hajime Arai, Masayoshi Kajimura, Hiroyuki Hanai, Masamitsu Tanaka, Haruhiko Sugimura

Cancer Sci. 2004 Feb; 95(2): 136–141. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb03194.x

PMCID:: PMC11159731

Abstract Article PDF–745K

Select item 107134242.

EphA2 as a phase separation protein associated with ferroptosis and immune cell infiltration in colorectal cancer

Yanling Li, Qiu Peng, Lujuan Wang

Aging (Albany NY) 2023 Nov 30; 15(22): 12952–12965. Published online 2023 Nov 16. doi: 10.18632/aging.205212

PMCID:: PMC10713424

Abstract Article PDF–1.9M

Select item 101969873.

Cellular stress induces non-canonical activation of the receptor tyrosine kinase EphA2 through the p38-MK2-RSK signaling pathway

Yue Zhou, Ryota Oki, Akihiro Tanaka, Leixin Song, Atsushi Takashima, Naru Hamada, Satoru Yokoyama, Seiji Yano, Hiroaki Sakurai

J Biol Chem. 2023 May; 299(5): 104699. Published online 2023 Apr 12. doi: 10.1016/j.jbc.2023.104699

PMCID:: PMC10196987

Abstract Article PDF–2.2M

Select item 101913324.

EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells

Xiao-Dong Dong, Yan Li, Ying Li, Cong Sun, Shang-Xin Liu, Hao Duan, Run Cui, Qian Zhong, Yong-Gao Mou, Le Wen, Bo Yang, Mu-Sheng Zeng, Min-Hua Luo, Hua Zhang

PLoS Pathog. 2023 May; 19(5): e1011304. Published online 2023 May 5. doi: 10.1371/journal.ppat.1011304

PMCID:: PMC10191332

Abstract Article PDF–1.9M

Select item 99318335.

Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance

Lucien Torlot, Anna Jarzab, Johanna Albert, Ágnes Pók-Udvari, Arndt Stahler, Julian Walter Holch, Marco Gerlinger, Volker Heinemann, Frederick Klauschen, Thomas Kirchner, Jörg Kumbrink, Bernhard Küster, Andreas Jung

J Cancer Res Clin Oncol. 2023; 149(2): 669–682. Published online 2022 Nov 19. doi: 10.1007/s00432-022-04416-0

PMCID:: PMC9931833

Abstract Article PDF–1.9M

Select item 95195566.

EphA2 on urinary extracellular vesicles as a novel biomarker for bladder cancer diagnosis and its effect on the invasiveness of bladder cancer

Eisuke Tomiyama, Kazutoshi Fujita, Kyosuke Matsuzaki, Ryohei Narumi, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yoko Koh, Makoto Matsushita, Yujiro Hayashi, Mamoru Hashimoto, Eri Banno, Taigo Kato, Koji Hatano, Atsunari Kawashima, Motohide Uemura, Ryo Ukekawa, Tetsuya Takao, Shingo Takada, Hirotsugu Uemura, Jun Adachi, Takeshi Tomonaga, Norio Nonomura

Br J Cancer. 2022 Oct 19; 127(7): 1312–1323. Published online 2022 Jul 6. doi: 10.1038/s41416-022-01860-0

PMCID:: PMC9519556

Abstract Article PDF–1.7M

Select item 88071517.

EphA2 Is a Lung Epithelial Cell Receptor for Pneumocystis β-Glucans

Theodore J Kottom, Kyle Schaefbauer, Eva M Carmona, Andrew H Limper

J Infect Dis. 2022 Feb 1; 225(3): 525–530. Published online 2021 Jul 21. doi: 10.1093/infdis/jiab384

PMCID:: PMC8807151

Abstract Article PDF–699K

Select item 86399868.

Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker

Bernhard C. Lechtenberg, Marina P. Gehring, Taylor P. Light, Christopher R. Horne, Mike W. Matsumoto, Kalina Hristova, Elena B. Pasquale

Nat Commun. 2021; 12: 7047. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27343-z

PMCID:: PMC8639986

Abstract Article PDF–6.7M

Select item 86165269.

EphA2 Expression in Bone Sarcomas: Bioinformatic Analyses and Preclinical Characterization in Patient-Derived Models of Osteosarcoma, Ewing’s Sarcoma and Chondrosarcoma

Giorgia Giordano, Alessandra Merlini, Giulio Ferrero, Giulia Mesiano, Erika Fiorino, Silvia Brusco, Maria Laura Centomo, Valeria Leuci, Lorenzo D’Ambrosio, Massimo Aglietta, Dario Sangiolo, Giovanni Grignani, Ymera Pignochino

Cells. 2021 Nov; 10(11): 2893. Published online 2021 Oct 26. doi: 10.3390/cells10112893

PMCID:: PMC8616526

Abstract Article PDF–6.7M

Select item 850882610.

Biallelic Variants in EPHA2 Identified in Three Large Inbred Families with Early-Onset Cataract

Priya Jarwar, Shakeel Ahmed Sheikh, Yar Muhammad Waryah, Ikram Uddin Ujjan, Saima Riazuddin, Ali Muhammad Waryah, Zubair M. Ahmed

Int J Mol Sci. 2021 Oct; 22(19): 10655. Published online 2021 Sep 30. doi: 10.3390/ijms221910655

PMCID:: PMC8508826

Abstract Article PDF–1.1M

Select item 839737111.

Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility

Zhongwen Chen, Dongmyung Oh, Kabir Hassan Biswas, Ronen Zaidel-Bar, Jay T Groves

eLife. 2021; 10: e67379. Published online 2021 Aug 20. doi: 10.7554/eLife.67379

PMCID:: PMC8397371

Abstract Article PDF–8.5M

Select item 825466012.

Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells

Dan Li, Xiaoyan Han, Zhennan Zhao, Yi Lu, Jin Yang

Mol Vis. 2021; 27: 403–414. Published online 2021 Jul 1.

PMCID:: PMC8254660

Abstract Article PDF–3.4M

Select item 821950513.

Functional analysis of deleterious EPHA2 SNPs in lens epithelial cells

Dan Li, Xiaoyan Han, Zhennan Zhao, Yi Lu, Jin Yang

Mol Vis. 2021; 27: 384–395. Published online 2021 Jun 23.

PMCID:: PMC8219505

Abstract Article PDF–3.4M

Select item 805834214.

Drug-resistant cancer cell-derived exosomal EphA2 promotes breast cancer metastasis via the EphA2-Ephrin A1 reverse signaling

Zicong Gao, Xingxing Han, Yuying Zhu, He Zhang, Ran Tian, Zhiyong Wang, Yanfen Cui, Zhaosong Wang, Ruifang Niu, Fei Zhang

Cell Death Dis. 2021 May; 12(5): 414. Published online 2021 Apr 20. doi: 10.1038/s41419-021-03692-x

PMCID:: PMC8058342

Abstract Article PDF–6.5M

Select item 803521215.

Oncogenic Functions and Therapeutic Targeting of EphA2 in Cancer

Kalin Wilson, Eileen Shiuan, Dana M. Brantley-Sieders

Oncogene. Author manuscript; available in PMC 2021 Sep 8.

Published in final edited form as: Oncogene. 2021 Apr; 40(14): 2483–2495. Published online 2021 Mar 8. doi: 10.1038/s41388-021-01714-8

PMCID:: PMC8035212

Abstract Article PDF–732K

Select item 801656216.

EPHA2 Promotes the Invasion and Migration of Human Tongue Squamous Cell Carcinoma Cal-27 Cells by Enhancing AKT/mTOR Signaling Pathway

Fengqin Wang, Hanzhong Zhang, Zhigang Cheng

Biomed Res Int. 2021; 2021: 4219690. Published online 2021 Mar 24. doi: 10.1155/2021/4219690

PMCID:: PMC8016562

Abstract Article PDF–3.7M

Select item 793855717.

Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids

Ezgi Oner, Mustafa Kotmakci, Anne-Marie Baird, Steven G. Gray, Bilge Debelec Butuner, Emir Bozkurt, Ayse Gulten Kantarci, Stephen P. Finn

J Nanobiotechnology. 2021; 19: 71. Published online 2021 Mar 8. doi: 10.1186/s12951-021-00781-z

PMCID:: PMC7938557

Abstract Article PDF–3.9M

Select item 792121518.

Non-canonical EphA2 signaling is a driver of tumor-endothelial cell interactions and metastatic dissemination in BRAF inhibitor resistant melanoma

Chao Zhang, Inna Smalley, Michael F. Emmons, Ritin Sharma, Victoria Izumi, Jane Messina, John M. Koomen, Elena B. Pasquale, Peter A. Forsyth, Keiran S. M. Smalley

J Invest Dermatol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: J Invest Dermatol. 2021 Apr; 141(4): 840–851.e4. Published online 2020 Sep 2. doi: 10.1016/j.jid.2020.08.012

PMCID:: PMC7921215

Abstract Article PDF–2.5M

Select item 746636019.

EphA2-enriched exosomes promote cell migration and are a potential diagnostic serum marker in pancreatic cancer

Qian Wei, Lijuan Wei, Jingya Zhang, Ze Li, Honglei Feng, Li Ren

Mol Med Rep. 2020 Oct; 22(4): 2941–2947. Published online 2020 Jul 28. doi: 10.3892/mmr.2020.11384

PMCID:: PMC7466360

Abstract Article PDF–816K

Select item 744997120.

Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway

Yi-Ping Xiang, Ta Xiao, Qi-Guang Li, Shan-Shan Lu, Wei Zhu, Yun-Ya Liu, Jie-Ya Qiu, Zheng-Hui Song, Wei Huang, Hong Yi, Yao-Yun Tang, Zhi-Qiang Xiao

Cell Death Dis. 2020 Aug; 11(8): 709. Published online 2020 Aug 27. doi: 10.1038/s41419-020-02831-0

PMCID:: PMC7449971

Abstract Article PDF–3.6M

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