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Select item 47660141.

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding

Joseph A. Newman, Christopher D. O. Cooper, Anette K. Roos, Hazel Aitkenhead, Udo C. T. Oppermann, Hearn J. Cho, Roman Osman, Opher Gileadi

PLoS One. 2016; 11(2): e0148762. Published online 2016 Feb 24. doi: 10.1371/journal.pone.0148762

PMCID:: PMC4766014

Abstract Article PDF–3.3M

Select item 3438142.

Coordination of DNA Damage Responses via the Smc5/Smc6 Complex

Susan H. Harvey, Daniel M. Sheedy, Andrew R. Cuddihy, Matthew J. O'Connell

Mol Cell Biol. 2004 Jan; 24(2): 662–674. doi: 10.1128/MCB.24.2.662-674.2004

PMCID:: PMC343814

Abstract Article PDF–834K

Select item 62064843.

PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner

Wei Xu, Chunqiang Ma, Qi Zhang, Rong Zhao, Dan Hu, Xuewu Zhang, Junbo Chen, Fang Liu, Kailang Wu, Yingle Liu, Jianguo Wu

J Virol. 2018 Nov 15; 92(22): e00825-18. Prepublished online 2018 Sep 5. Published online 2018 Oct 29. doi: 10.1128/JVI.00825-18

PMCID:: PMC6206484

Abstract Article PDF–5.1M

Select item 34607894.

Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis

Xiaojun Hou, Wei Zhang, Zhenyu Xiao, Haiyun Gan, Xiwen Lin, Shangying Liao, Chunsheng Han

BMC Genomics. 2012; 13: 495. Published online 2012 Sep 19. doi: 10.1186/1471-2164-13-495

PMCID:: PMC3460789

Abstract Article PDF–1.7M

Select item 49663125.

Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease

Saskia N. van der Crabben, Marije P. Hennus, Grant A. McGregor, Deborah I. Ritter, Sandesh C.S. Nagamani, Owen S. Wells, Magdalena Harakalova, Ivan K. Chinn, Aaron Alt, Lucie Vondrova, Ron Hochstenbach, Joris M. van Montfrans, Suzanne W. Terheggen-Lagro, Stef van Lieshout, Markus J. van Roosmalen, Ivo Renkens, Karen Duran, Isaac J. Nijman, Wigard P. Kloosterman, Eric Hennekam, Jordan S. Orange, Peter M. van Hasselt, David A. Wheeler, Jan J. Palecek, Alan R. Lehmann, Antony W. Oliver, Laurence H. Pearl, Sharon E. Plon, Johanne M. Murray, Gijs van Haaften

J Clin Invest. 2016 Aug 1; 126(8): 2881–2892. Published online 2016 Jul 18. doi: 10.1172/JCI82890

PMCID:: PMC4966312

Abstract Article PDF–1.1M

Select item 11902426.

Human MMS21/NSE2 Is a SUMO Ligase Required for DNA Repair

Patrick Ryan Potts, Hongtao Yu

Mol Cell Biol. 2005 Aug; 25(16): 7021–7032. doi: 10.1128/MCB.25.16.7021-7032.2005

PMCID:: PMC1190242

Abstract Article PDF–780K

Select item 25559367.

Nse1 RING-like Domain Supports Functions of the Smc5-Smc6 Holocomplex in Genome Stability

Stephanie Pebernard, J. Jefferson P. Perry, John A. Tainer, Michael N. Boddy

Mol Biol Cell. 2008 Oct; 19(10): 4099–4109. doi: 10.1091/mbc.E08-02-0226

PMCID:: PMC2555936

Abstract Article PDF–1.1M

Select item 15231878.

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks

Patrick Ryan Potts, Matthew H Porteus, Hongtao Yu

EMBO J. 2006 Jul 26; 25(14): 3377–3388. Published online 2006 Jun 29. doi: 10.1038/sj.emboj.7601218

PMCID:: PMC1523187

Abstract Article PDF–260K

Select item 22587589.

Identification of the Proteins, Including MAGEG1, That Make Up the Human SMC5-6 Protein Complex

Elaine M. Taylor, Alice C. Copsey, Jessica J. R. Hudson, Susanne Vidot, Alan R. Lehmann

Mol Cell Biol. 2008 Feb; 28(4): 1197–1206. Published online 2007 Dec 17. doi: 10.1128/MCB.00767-07

PMCID:: PMC2258758

Abstract Article PDF–801K

Select item 304543610.

Interactions between the Nse3 and Nse4 Components of the SMC5-6 Complex Identify Evolutionarily Conserved Interactions between MAGE and EID Families

Jessica J. R. Hudson, Katerina Bednarova, Lucie Kozakova, Chunyan Liao, Marc Guerineau, Rita Colnaghi, Susanne Vidot, Jaromir Marek, Sreenivas R. Bathula, Alan R. Lehmann, Jan Palecek

PLoS One. 2011; 6(2): e17270. Published online 2011 Feb 25. doi: 10.1371/journal.pone.0017270

PMCID:: PMC3045436

Abstract Article PDF–1.7M

Select item 450978811.

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

Jennifer M. Doyle, Jinlan Gao, Jiawei Wang, Maojun Yang, Patrick Ryan Potts

Mol Cell. Author manuscript; available in PMC 2015 Jul 21.

Published in final edited form as: Mol Cell. 2010 Sep 24; 39(6): 963–974. doi: 10.1016/j.molcel.2010.08.029

PMCID:: PMC4509788

Abstract Article PDF–1.3M

Select item 866666512.

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

Jean-Philippe Guégan, Justine Pollet, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Marcus E. Peter, Patrick Legembre

iScience. 2021 Dec 17; 24(12): 103538. Published online 2021 Dec 1. doi: 10.1016/j.isci.2021.103538

PMCID:: PMC8666665

Abstract Article PDF–3.2M

Select item 913694313.

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Bhaskar Saha, Michelle Salemi, Geneva L. Williams, Seeun Oh, Michael L. Paffett, Brett Phinney, Michael A. Mandell

Cell Rep. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110797. doi: 10.1016/j.celrep.2022.110797

PMCID:: PMC9136943

Abstract Article PDF–3.2M

Select item 31093414.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 642645515.

Mapping the genetic landscape of human cells

Max A. Horlbeck, Albert Xu, Min Wang, Neal K. Bennett, Chong Y. Park, Derek Bogdanoff, Britt Adamson, Eric D. Chow, Martin Kampmann, Tim R. Peterson, Ken Nakamura, Michael A. Fischbach, Jonathan S. Weissman, Luke A. Gilbert

Cell. Author manuscript; available in PMC 2019 Aug 9.

Published in final edited form as: Cell. 2018 Aug 9; 174(4): 953–967.e22. Published online 2018 Jul 19. doi: 10.1016/j.cell.2018.06.010

PMCID:: PMC6426455

Abstract Article PDF–3.6M

Select item 810809316.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 954034517.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 577033718.

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions

Kinga Winczura, Manfred Schmid, Claudia Iasillo, Kelly R. Molloy, Lea Mørch Harder, Jens S. Andersen, John LaCava, Torben Heick Jensen

Cell Rep. 2018 Jan 2; 22(1): 44–58. Published online 2018 Jan 2. doi: 10.1016/j.celrep.2017.12.037

PMCID:: PMC5770337

Abstract Article

Select item 970808619.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 694204420.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

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