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Select item 110211801.

The eukaryotic translation initiation factor eIF4E unexpectedly acts in splicing thereby coupling mRNA processing with translation: eIF4E induces widescale splicing reprogramming providing system‐wide connectivity between splicing, nuclear mRNA export and translation

Katherine L. B. Borden

Bioessays. 2024 Jan; 46(1): 2300145. Published online 2023 Nov 5. doi: 10.1002/bies.202300145

PMCID:: PMC11021180

Abstract Article PDF–1.1M

Select item 95504362.

Expression of eIF4E Gene in Glioma and Its Sensitivity to Oxidative Stress

Jian Liang, Yaoqiang Yang, Xing Li, Guangmou Cai, Jianxuan Cao, Bo Zhang

Oxid Med Cell Longev. 2022; 2022: 5413035. Published online 2022 Oct 3. doi: 10.1155/2022/5413035

PMCID:: PMC9550436

Abstract Article PDF–2.1M

Select item 93456143.

Down-regulated Circ_0000190 promotes cervical cancer by facilitating the activity of proto-oncogene protein EIF4E

Chengcheng Yang, Jia Xie, Qian Chen, Yisi Yang

Cell Cycle. 2022; 21(13): 1349–1359. Published online 2022 Apr 13. doi: 10.1080/15384101.2021.2018212

PMCID:: PMC9345614

Abstract Article PDF–3.5M

Select item 86503344.

High expression of eIF4E is associated with tumor macrophage infiltration and leads to poor prognosis in breast cancer

Fan Li, Huizhi Sun, Yue Li, Xiaoyu Bai, Xueyi Dong, Nan Zhao, Jie Meng, Baocun Sun, Danfang Zhang

BMC Cancer. 2021; 21: 1305. Published online 2021 Dec 7. doi: 10.1186/s12885-021-09010-0

PMCID:: PMC8650334

Abstract Article PDF–9.7M

Select item 84606145.

Deep Computational Analysis Details Dysregulation of Eukaryotic Initiation Complex (eIF4F) in Human Cancers

Su Wu, Gerhard Wagner

Cell Syst. Author manuscript; available in PMC 2022 Sep 22.

Published in final edited form as: Cell Syst. 2021 Sep 22; 12(9): 907–923.e6. Published online 2021 Aug 5. doi: 10.1016/j.cels.2021.07.002

PMCID:: PMC8460614

Abstract Article PDF–4.1M

Select item 83069746.

Translation Initiation Regulated by RNA-Binding Protein in Mammals: The Modulation of Translation Initiation Complex by Trans-Acting Factors

Akira Fukao, Takumi Tomohiro, Toshinobu Fujiwara

Cells. 2021 Jul; 10(7): 1711. Published online 2021 Jul 6. doi: 10.3390/cells10071711

PMCID:: PMC8306974

Abstract Article PDF–1.6M

Select item 77878417.

eIF4E Overexpression Is Associated with Poor Prognoses of Ovarian Cancer

Jun Zheng, Xueqing Li, Chunyan Zhang, Yiqiang Zhang

Anal Cell Pathol (Amst) 2020; 2020: 8984526. Published online 2020 Dec 12. doi: 10.1155/2020/8984526

PMCID:: PMC7787841

Abstract Article PDF–1.2M

Select item 77140728.

The high‐risk HPV E6 proteins modify the activity of the eIF4E protein via the MEK/ERK and AKT/PKB pathways

Vicente Morales‐Garcia, Adriana Contreras‐Paredes, Eduardo Martinez‐Abundis, Nancy P. Gomez‐Crisostomo, Marcela Lizano, Fernanda Hernandez‐Landero, Erick de la Cruz‐Hernandez

FEBS Open Bio. 2020 Dec; 10(12): 2541–2552. Published online 2020 Nov 19. doi: 10.1002/2211-5463.12987

PMCID:: PMC7714072

Abstract Article PDF–2.6M

Select item 75190739.

Causal association between mTOR-dependent EIF-4E and EIF-4A circulating protein levels and type 2 diabetes: a Mendelian randomization study

Ghada A. Soliman, C. Mary Schooling

Sci Rep. 2020; 10: 15737. Published online 2020 Sep 25. doi: 10.1038/s41598-020-71987-8

PMCID:: PMC7519073

Abstract Article PDF–2.0M

Select item 725550310.

Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition

Dilraj Lama, Chandra S. Verma

Protein Sci. 2020 Jun; 29(6): 1373–1386. Published online 2019 Dec 16. doi: 10.1002/pro.3798

PMCID:: PMC7255503

Abstract Article PDF–11M

Select item 718557411.

The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer

Sara Karaki, Claudia Andrieu, Hajer Ziouziou, Palma Rocchi

Adv Protein Chem Struct Biol. 2015; 101: 1–26. Published online 2015 Oct 23. doi: 10.1016/bs.apcsb.2015.09.001

PMCID:: PMC7185574

Abstract Article PDF–4.9M

Select item 714441412.

Role of eIF4E on epithelial‐mesenchymal transition, invasion, and chemoresistance of prostate cancer cells

Xujie Liu, Amita M Vaidya, Da Sun, Yan Zhang, Nadia Ayat, Andrew Schilb, Zheng‐Rong Lu

Cancer Commun (Lond) 2020 Mar; 40(2-3): 126–131. Published online 2020 Mar 18. doi: 10.1002/cac2.12011

PMCID:: PMC7144414

Article PDF–1.4M

Select item 714201913.

Phosphorylation independent eIF4E translational reprogramming of selective mRNAs determines tamoxifen resistance in breast cancer

Chun Gong, Ho Tsoi, Ka Chun Mok, Jenny Cheung, Ellen P. S. Man, Kazunari Fujino, Ashely Wong, Eric W. F. Lam, Ui-Soon Khoo

Oncogene. 2020; 39(15): 3206–3217. Published online 2020 Feb 17. doi: 10.1038/s41388-020-1210-y

PMCID:: PMC7142019

Abstract Article PDF–2.3M

Select item 666190414.

Nuclear eIF4E Stimulates 3′-End Cleavage of Target RNAs

Margaret Rose Davis, Mildred Delaleau, Katherine L.B. Borden

Cell Rep. Author manuscript; available in PMC 2019 Jul 29.

Published in final edited form as: Cell Rep. 2019 Apr 30; 27(5): 1397–1408.e4. doi: 10.1016/j.celrep.2019.04.008

PMCID:: PMC6661904

Abstract Article PDF–1.4M

Select item 642673215.

eIF4E基因在非小细胞肺癌中的表达及意义

张波, 朱成楚, 陈保富, 章霞, 叶敏华, 林爱芬

Zhongguo Fei Ai Za Zhi. 2010 Dec 20; 13(12): 1132–1135. Chinese. doi: 10.3779/j.issn.1009-3419.2010.12.10

PMCID:: PMC6426732

Abstract Article PDF–789K

Select item 632730516.

Translation initiation factor eIF4E is a target for tumor cell radiosensitization

Thomas J. Hayman, Eli S. Williams, Muhammad Jamal, Uma T. Shankavaram, Kevin Camphausen, Philip J. Tofilon

Cancer Res. Author manuscript; available in PMC 2019 Jan 10.

Published in final edited form as: Cancer Res. 2012 May 1; 72(9): 2362–2372. Published online 2012 Mar 7. doi: 10.1158/0008-5472.CAN-12-0329

PMCID:: PMC6327305

Abstract Article PDF–1.1M

Select item 570520917.

The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

Hiba Ahmad Zahreddine, Biljana Culjkovic-Kraljacic, Audrey Emond, Filippa Pettersson, Ronald Midura, Mark Lauer, Sonia Del Rincon, Valbona Cali, Sarit Assouline, Wilson H Miller, Vincent Hascall, Katherine LB Borden

eLife. 2017; 6: e29830. Published online 2017 Nov 7. doi: 10.7554/eLife.29830

PMCID:: PMC5705209

Abstract Article PDF–5.7M

Select item 543586518.

A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

Laurent Volpon, Biljana Culjkovic-Kraljacic, Hye Seon Sohn, Alexis Blanchet-Cohen, Michael J. Osborne, Katherine L.B. Borden

RNA. 2017 Jun; 23(6): 927–937. doi: 10.1261/rna.060137.116

PMCID:: PMC5435865

Abstract Article PDF–1.6M

Select item 534184219.

eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma

Ting Liu, Rong Li, Hui Zhao, Juan Deng, Ying Long, Meng-ting Shuai, Qian Li, Huan Gu, Ya-qi Chen, Ai-min Leng

Oncotarget. 2016 Oct 11; 7(41): 66851–66864. Published online 2016 Aug 30. doi: 10.18632/oncotarget.11694

PMCID:: PMC5341842

Abstract Article PDF–5.8M

Select item 505516320.

peIF4E as an independent prognostic factor and a potential therapeutic target in diffuse infiltrating astrocytomas

Elena Martínez‐Sáez, Vicente Peg, Arantxa Ortega‐Aznar, Francisco Martínez‐Ricarte, Jessica Camacho, Javier Hernández‐Losa, Joan Carles Ferreres Piñas, Santiago Ramón y Cajal

Cancer Med. 2016 Sep; 5(9): 2501–2512. Published online 2016 Jul 20. doi: 10.1002/cam4.817