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Select item 65466831.

Knockdown of TRIM65 inhibits autophagy and cisplatin resistance in A549/DDP cells by regulating miR-138-5p/ATG7

Xufeng Pan, Yong Chen, Yuzhou Shen, Jicheng Tantai

Cell Death Dis. 2019 Jun; 10(6): 429. Published online 2019 Jun 3. doi: 10.1038/s41419-019-1660-8

PMCID:: PMC6546683

Article PDF–3.8M

Select item 53484102.

Knockdown of TRIM65 inhibits lung cancer cell proliferation, migration and invasion: A therapeutic target in human lung cancer

Xiao-Lin Wang, Wei-Ping Shi, Hong-Can Shi, Shi-Chun Lu, Kang Wang, Chao Sun, Jian-Sheng He, Wei-Guo Jin, Xiao-Xia Lv, Hui Zou, Yu-Sheng Shu

Oncotarget. 2016 Dec 6; 7(49): 81527–81540. Published online 2016 Nov 5. doi: 10.18632/oncotarget.13131

PMCID:: PMC5348410

Article PDF–7.1M

Select item 94023073.

TRIM65 Promotes Malignant Cell Behaviors in Triple-Negative Breast Cancer by Impairing the Stability of LATS1 Protein

Yongbin Lu, Yi Xiao, Jingru Yang, Hongxin Su, Xiaobin Zhang, Fei Su, Baohong Tian, Da Zhao, Xiaoling Ling, Tao Zhang

Oxid Med Cell Longev. 2022; 2022: 4374978. Published online 2022 Aug 17. doi: 10.1155/2022/4374978

PMCID:: PMC9402307

Article PDF–3.2M

Select item 93406364.

TRIM65 determines the fate of a novel subtype of pituitary neuroendocrine tumors via ubiquitination and degradation of TPIT

Hong Yao, Wanqun Xie, Yuting Dai, Yanting Liu, Weiting Gu, Jianfeng Li, Liang Wu, Jing Xie, Weiwei Rui, Bohan Ren, Li Xue, Yijun Cheng, Shaojian Lin, Changsheng Li, Hao Tang, Yu Wang, Meiqing Lou, Xiaobiao Zhang, Ronggui Hu, Hanbing Shang, Jinyan Huang, Zhe Bao Wu

Neuro Oncol. 2022 Aug; 24(8): 1286–1297. Published online 2022 Feb 26. doi: 10.1093/neuonc/noac053

PMCID:: PMC9340636

Article PDF–21M

Select item 67562365.

Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation

Daici Chen, Yichen Li, Xiaowen Zhang, Haiyong Wu, Qian Wang, Jian Cai, Yanmei Cui, Huanliang Liu, Ping Lan, Jianping Wang, Zihuan Yang, Lei Wang

Oncogene. 2019; 38(37): 6429–6444. Published online 2019 Jul 22. doi: 10.1038/s41388-019-0891-6

PMCID:: PMC6756236

Article PDF–5.6M

Select item 52418036.

Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA

Evgenij Fiskin, Sagar Bhogaraju, Lina Herhaus, Sissy Kalayil, Marcel Hahn, Ivan Dikic

Nat Commun. 2017; 8: 14004. Published online 2017 Jan 13. doi: 10.1038/ncomms14004

PMCID:: PMC5241803

Article PDF–4.9M

Select item 31221477.

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE Consortium

Myriam Fornage, Stephanie Debette, Joshua C. Bis, Helena Schmidt, M. Arfan Ikram, Carole Dufouil, Sigurdur Sigurdsson, Thomas Lumley, Anita L. DeStefano, Franz Fazekas, Henri A. Vrooman, Dean K. Shibata, Pauline Maillard, Alex Zijdenbos, Albert V. Smith, Haukur Gudnason, Renske de Boer, Mary Cushman, Bernard Mazoyer, Gerardo Heiss, Meike W. Vernooij, Christian Enzinger, Nicole L. Glazer, Alexa Beiser, David S. Knopman, Margherita Cavalieri, Wiro J. Niessen, Tamara B. Harris, Katja Petrovic, Oscar L. Lopez, Rhoda Au, Jean-Charles Lambert, Albert Hofman, Rebecca F. Gottesman, Melissa Garcia, Susan R. Heckbert, Larry D. Atwood, Diane J. Catellier, Andre G. Uitterlinden, Qiong Yang, Nicholas L. Smith, Thor Aspelund, Jose R. Romero, Kenneth Rice, Kent D. Taylor, Michael A. Nalls, Jerome I. Rotter, Richey Sharret, Cornelia M. van Duijn, Philippe Amouyel, Philip A. Wolf, Vilmundur Gudnason, Aad van der Lugt, Eric Boerwinkle, Bruce M. Psaty, Sudha Seshadri, Christophe Tzourio, Monique M.B. Breteler, Thomas H. Mosley, Reinhold Schmidt, W.T. Longstreth, Charles DeCarli, Lenore J. Launer

Ann Neurol. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Ann Neurol. 2011 Jun; 69(6): 928–939. doi: 10.1002/ana.22403

PMCID:: PMC3122147

Article PDF–429K

Select item 84362058.

LncRNA LINC00963 promotes colorectal cancer cell proliferation and metastasis by regulating miR-1281 and TRIM65

Haidong Lv, Dixia Zhou, Guoqing Liu

Mol Med Rep. 2021 Nov; 24(5): 781. Published online 2021 Sep 7. doi: 10.3892/mmr.2021.12421

PMCID:: PMC8436205

Article PDF–11M

Select item 71817229.

TRIM65 E3 ligase targets VCAM-1 degradation to limit LPS-induced lung inflammation

Yong Li, Xuan Huang, Fang Guo, Tianhua Lei, Shitao Li, Paula Monaghan-Nichols, Zhisheng Jiang, Hong-Bo Xin, Mingui Fu

J Mol Cell Biol. 2020 Mar; 12(3): 190–201. Published online 2019 Jul 16. doi: 10.1093/jmcb/mjz077

PMCID:: PMC7181722

Article PDF–1.6M

Select item 552091310.

ARRDC4 regulates enterovirus 71-induced innate immune response by promoting K63 polyubiquitination of MDA5 through TRIM65

Jun Meng, Zhenyu Yao, Yaqing He, Renli Zhang, Yanwei Zhang, Xiangjie Yao, Hong Yang, Long Chen, Zhen Zhang, Hailong Zhang, Xueqin Bao, Gang Hu, Tangchun Wu, Jinquan Cheng

Cell Death Dis. 2017 Jun; 8(6): e2866. Published online 2017 Jun 8. doi: 10.1038/cddis.2017.257

PMCID:: PMC5520913

Article PDF–1.4M

Select item 529485011.

TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity

Xueting Lang, Tiantian Tang, Tengchuan Jin, Chen Ding, Rongbin Zhou, Wei Jiang

J Exp Med. 2017 Feb; 214(2): 459–473. doi: 10.1084/jem.20160592

PMCID:: PMC5294850

Article PDF–2.8M

Select item 500852712.

Analysis of genetic polymorphisms associated with leukoaraiosis in the southern Chinese population: A case–control study

Wen-Qing Huang, Hui-Ming Ye, Fang-Fang Li, Ke-Hui Yi, Ya Zhang, Liang-Liang Cai, Hui-Nuan Lin, Qing Lin, Chi-Meng Tzeng

Medicine (Baltimore) 2016 Aug; 95(35): e3857. Published online 2016 Sep 2. doi: 10.1097/MD.0000000000003857

PMCID:: PMC5008527

Article PDF–425K

Select item 842743013.

The E3 Ubiquitin Ligase TRIM65 Negatively Regulates Inflammasome Activation Through Promoting Ubiquitination of NLRP3

Tiantian Tang, Ping Li, Xinhui Zhou, Rui Wang, Xiuqin Fan, Mengyi Yang, Kemin Qi

Front Immunol. 2021; 12: 741839. Published online 2021 Aug 26. doi: 10.3389/fimmu.2021.741839

PMCID:: PMC8427430

Article PDF–2.1M

Select item 818367614.

Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases

Kazuki Kato, Sadeem Ahmad, Zixiang Zhu, Janet M. Young, Xin Mu, Sehoon Park, Harmit S. Malik, Sun Hur

Mol Cell. Author manuscript; available in PMC 2021 Jun 7.

Published in final edited form as: Mol Cell. 2021 Feb 4; 81(3): 599–613.e8. Published online 2020 Dec 28. doi: 10.1016/j.molcel.2020.11.047

PMCID:: PMC8183676

Article PDF–3.6M

Select item 488910515.

Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins

Hirotaka Takahashi, Atsushi Uematsu, Satoshi Yamanaka, Mei Imamura, Tatsuro Nakajima, Kousuke Doi, Saki Yasuoka, Chikako Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki

PLoS One. 2016; 11(6): e0156718. Published online 2016 Jun 1. doi: 10.1371/journal.pone.0156718

PMCID:: PMC4889105

Article PDF–3.3M

Select item 812022716.

KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1

Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng

Theranostics. 2021; 11(13): 6278–6292. Published online 2021 Apr 15. doi: 10.7150/thno.57455

PMCID:: PMC8120227

Article PDF–2.7M

Select item 457686817.

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity

Tomonori Kimura, Ashish Jain, Seong Won Choi, Michael A. Mandell, Kate Schroder, Terje Johansen, Vojo Deretic

J Cell Biol. 2015 Sep 14; 210(6): 973–989. doi: 10.1083/jcb.201503023

PMCID:: PMC4576868

Article PDF–3.1M

Select item 273665218.

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

Sjoerd J L van Wijk, Sjoerd J de Vries, Patrick Kemmeren, Anding Huang, Rolf Boelens, Alexandre M J J Bonvin, H Th Marc Timmers

Mol Syst Biol. 2009; 5: 295. Published online 2009 Aug 18. doi: 10.1038/msb.2009.55

Correction in:: Mol Syst Biol. 2009; 5: 317.

PMCID:: PMC2736652

Article PDF–5.6M

Select item 339495219.

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson

Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162

PMCID:: PMC3394952

Article PDF–3.3M

Select item 276528020.

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson

Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109

PMCID:: PMC2765280

Article PDF–425K

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