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Select item 111586731.

Erythropoietin‐producing hepatocyte B6 variant‐derived peptides with the ability to induce glioma‐reactive cytotoxic T lymphocytes in human leukocyte antigen‐A2⁺ glioma patients

Mingyue Jin, Yoshihiro Komohara, Shigeki Shichijo, Ryuya Yamanaka, Junichi Nikawa, Kyogo Itoh, Akira Yamada

Cancer Sci. 2008 Aug; 99(8): 1656–1662. Published online 2008 Aug 14. doi: 10.1111/j.1349-7006.2008.00866.x

PMCID:: PMC11158673

Abstract Article PDF–353K

Select item 79970482.

Structure of the EphB6 receptor ectodomain

Emilia O. Mason, Yehuda Goldgur, Dorothea Robev, Andrew Freywald, Dimitar B. Nikolov, Juha P. Himanen

PLoS One. 2021; 16(3): e0247335. Published online 2021 Mar 26. doi: 10.1371/journal.pone.0247335

PMCID:: PMC7997048

Abstract Article PDF–2.1M

Select item 60624993.

EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumours

Behzad M. Toosi, Amr El Zawily, Luke Truitt, Matthew Shannon, Odette Allonby, Mohan Babu, John DeCoteau, Darrell Mousseau, Mohsin Ali, Tanya Freywald, Amanda Gall, Frederick S. Vizeacoumar, Morgan W. Kirzinger, C. Ronald Geyer, Deborah H. Anderson, TaeHyung Kim, Alana L. Welm, Peter Siegel, Franco J. Vizeacoumar, Anthony Kusalik, Andrew Freywald

Oncogene. 2018; 37(30): 4073–4093. Published online 2018 Apr 27. doi: 10.1038/s41388-018-0228-x

PMCID:: PMC6062499

Abstract Article PDF–4.2M

Select item 56767114.

The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment

Amr El Zawily, Emily McEwen, Behzad Toosi, Frederick S. Vizeacoumar, Tanya Freywald, Franco J. Vizeacoumar, Andrew Freywald

Sci Rep. 2017; 7: 14767. Published online 2017 Nov 7. doi: 10.1038/s41598-017-15200-3

PMCID:: PMC5676711

Abstract Article PDF–3.0M

Select item 52265665.

Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment

James M. Paul, Behzad Toosi, Frederick S. Vizeacoumar, Kalpana Kalyanasundaram Bhanumathy, Yue Li, Courtney Gerger, Amr El Zawily, Tanya Freywald, Deborah H. Anderson, Darrell Mousseau, Rani Kanthan, Zhaolei Zhang, Franco J. Vizeacoumar, Andrew Freywald

Oncotarget. 2016 Aug 2; 7(31): 50027–50042. Published online 2016 Jul 13. doi: 10.18632/oncotarget.10569

PMCID:: PMC5226566

Abstract Article PDF–12M

Select item 46376866.

High expression of EphB6 protein in tongue squamous cell carcinoma is associated with a poor outcome

Yingchun Dong, Jicheng Pan, Yanhong Ni, Xiaofeng Huang, Xiao Chen, Jiandong Wang

Int J Clin Exp Pathol. 2015; 8(9): 11428–11433. Published online 2015 Sep 1.

PMCID:: PMC4637686

Abstract Article PDF–856K

Select item 44982607.

Dynamic Interactions between Cancer Cells and the Embryonic Microenvironment Regulate Cell Invasion and Reveal EphB6 as a Metastasis Suppressor

Caleb M. Bailey, Paul M. Kulesa

Mol Cancer Res. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Mol Cancer Res. 2014 Sep; 12(9): 1303–1313. Published online 2014 May 16. doi: 10.1158/1541-7786.MCR-13-0673

PMCID:: PMC4498260

Abstract Article PDF–2.7M

Select item 35143098.

Mutations of the EPHB6 Receptor Tyrosine Kinase Induce a Pro-Metastatic Phenotype in Non-Small Cell Lung Cancer

Etmar Bulk, Jun Yu, Antje Hascher, Steffen Koschmieder, Rainer Wiewrodt, Utz Krug, Bernd Timmermann, Alessandro Marra, Ludger Hillejan, Karsten Wiebe, Wolfgang E. Berdel, Albrecht Schwab, Carsten Müller-Tidow

PLoS One. 2012; 7(12): e44591. Published online 2012 Dec 4. doi: 10.1371/journal.pone.0044591

PMCID:: PMC3514309

Abstract Article PDF–704K

Select item 31396439.

EphB6 Receptor Modulates Micro RNA Profile of Breast Carcinoma Cells

Lokesh Bhushan, Raj P. Kandpal

PLoS One. 2011; 6(7): e22484. Published online 2011 Jul 19. doi: 10.1371/journal.pone.0022484

PMCID:: PMC3139643

Abstract Article PDF–586K

Select item 15079810.

EphB6 crosslinking results in costimulation of T cells

Hongyu Luo, Guang Yu, Yulian Wu, Jiangping Wu

J Clin Invest. 2002 Oct 15; 110(8): 1141–1150. doi: 10.1172/JCI15883

PMCID:: PMC150798

Abstract Article PDF–1.7M

Select item 2712711.

Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma

Xao X. Tang, Huaqing Zhao, Marjorie E. Robinson, Brian Cohen, Avital Cnaan, Wendy London, Susan L. Cohn, Nai-Kong V. Cheung, Garrett M. Brodeur, Audrey E. Evans, Naohiko Ikegaki

Proc Natl Acad Sci U S A. 2000 Sep 26; 97(20): 10936–10941. Published online 2000 Sep 12. doi: 10.1073/pnas.190123297

PMCID:: PMC27127

Abstract Article PDF–333K

Select item 744157112.

The gut microbiota regulates autism-like behavior by mediating vitamin B₆ homeostasis in EphB6-deficient mice

Ying Li, Zheng-Yi Luo, Yu-Ying Hu, Yue-Wei Bi, Jian-Ming Yang, Wen-Jun Zou, Yun-Long Song, Shi Li, Tong Shen, Shu-Ji Li, Lang Huang, Ai-Jun Zhou, Tian-Ming Gao, Jian-Ming Li

Microbiome. 2020; 8: 120. Published online 2020 Aug 20. doi: 10.1186/s40168-020-00884-z

PMCID:: PMC7441571

Abstract Article PDF–5.2M

Select item 536362713.

The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation

Amr M. El Zawily, Behzad M. Toosi, Tanya Freywald, Vijaya V. Indukuri, Franco J. Vizeacoumar, Scot C. Leary, Andrew Freywald

Oncotarget. 2016 Nov 22; 7(47): 77865–77877. Published online 2016 Oct 24. doi: 10.18632/oncotarget.12838

PMCID:: PMC5363627

Abstract Article PDF–7.4M

Select item 517303914.

NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand

Angela M. Jones, Peter Ferguson, Jacqui Gardner, Serena Rooker, Tim Sutton, Antonio Ahn, Aniruddha Chatterjee, Vivienne M. Bickley, Makhdoom Sarwar, Patrick Emanuel, Diane Kenwright, Peter R. Shepherd, Michael R. Eccles

Oncotarget. 2016 Jul 5; 7(27): 41017–41030. Published online 2016 May 13. doi: 10.18632/oncotarget.9351

PMCID:: PMC5173039

Abstract Article PDF–4.5M

Select item 505874315.

EphB6 overexpression and Apc mutation together promote colorectal cancer

Dan Xu, Liang Yuan, Xin Liu, Mingqi Li, Fubin Zhang, XinYue Gu, Dongwei Zhang, Youlin Yang, Binbin Cui, Jinxue Tong, Jin Zhou, Zhiwei Yu

Oncotarget. 2016 May 24; 7(21): 31111–31121. Published online 2016 Apr 28. doi: 10.18632/oncotarget.9080

PMCID:: PMC5058743

Abstract Article PDF–5.5M

Select item 330729316.

Receptor Tyrosine Kinase Ephb6 Regulates Vascular Smooth Muscle Contractility and Modulates Blood Pressure in Concert with Sex Hormones

Hongyu Luo, Zenghui Wu, Johanne Tremblay, Eric Thorin, Junzheng Peng, Julie L. Lavoie, Bing Hu, Ekatherina Stoyanova, Guy Cloutier, Shijie Qi, Tao Wu, Mark Cameron, Jiangping Wu

J Biol Chem. 2012 Feb 24; 287(9): 6819–6829. Published online 2012 Jan 5. doi: 10.1074/jbc.M111.293365

PMCID:: PMC3307293

Abstract Article PDF–1.7M

Select item 758695517.

Cataloguing the dead: breathing new life into pseudokinase research

Safal Shrestha, Dominic P. Byrne, John A. Harris, Natarajan Kannan, Patrick A. Eyers

FEBS J. 2020 Oct; 287(19): 4150–4169. Published online 2020 Mar 10. doi: 10.1111/febs.15246

PMCID:: PMC7586955

Abstract Article PDF–7.7M

Select item 739200318.

DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression

Jia-En Wu, Yi-Ying Wu, Chia-Hao Tung, Yao-Tsung Tsai, Hsuan-Yu Chen, Yuh-Ling Chen, Tse-Ming Hong

Theranostics. 2020; 10(19): 8903–8923. Published online 2020 Jul 11. doi: 10.7150/thno.45785

PMCID:: PMC7392003

Abstract Article PDF–3.8M

Select item 654769519.

EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression

Sarah Yoon, Ji-Hye Choi, Sung Joo Kim, Eun-Ju Lee, Masaud Shah, Sangdun Choi, Hyun Goo Woo

Exp Mol Med. 2019 Jun; 51(6): 61. Published online 2019 Jun 3. doi: 10.1038/s12276-019-0261-z

PMCID:: PMC6547695

Abstract Article PDF–2.3M

Select item 616046820.

Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism

Tao Wu, Bi-Qi Zhang, John Raelson, Yu-Mei Yao, Huan-Dong Wu, Zao-Xian Xu, Francois-christophe Marois-blanchet, Muhammad Ramzan Tahir, Yujia Wang, W. Edward Bradley, Hongyu Luo, Jiangping Wu, Jian-Zhong Sheng, Shen-Jiang Hu

Sci Rep. 2018; 8: 14497. Published online 2018 Sep 27. doi: 10.1038/s41598-018-32836-x

PMCID:: PMC6160468

Abstract Article PDF–1.2M

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PMC Links for Gene (Select 2051) (38)
PMC
PREDICTED: Homo sapiens EPH receptor B6 (EPHB6), transcript variant X9, mRNA
PREDICTED: Homo sapiens EPH receptor B6 (EPHB6), transcript variant X9, mRNA
gi|2462489797|ref|XM_054328704.1|

Nucleotide
ephrin type-B receptor 6 isoform X4 [Homo sapiens]
ephrin type-B receptor 6 isoform X4 [Homo sapiens]
gi|1370509629|ref|XP_024302443.1|

Protein
ephrin type-B receptor 6 isoform X1 [Homo sapiens]
ephrin type-B receptor 6 isoform X1 [Homo sapiens]
gi|2462612795|ref|XP_054213438.1|

Protein
ephrin type-B receptor 6 isoform X3 [Homo sapiens]
ephrin type-B receptor 6 isoform X3 [Homo sapiens]
gi|2462612805|ref|XP_054213443.1|

Protein

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