PMC Links for Gene (Select 2122) - PMC

Michell M. Lozano Chinga, Alison A. Bertuch, Zeinab Afify, Kaylee Dollerschell, Joanne I. Hsu, Tami D. John, Emily S. Rao, R. Grant Rowe, Vijay G. Sankaran, Akiko Shimamura, David A. Williams, Taizo A. Nakano

Am J Med Genet A. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Am J Med Genet A. 2023 Jul; 191(7): 1826–1835. Published online 2023 Apr 17. doi: 10.1002/ajmg.a.63208

PMCID:: PMC10330190

Abstract Article PDF–793K

Select item 96488244.

Mapping the developing human cardiac endothelium at single-cell resolution identifies MECOM as a regulator of arteriovenous gene expression

Ian R McCracken, Ross Dobie, Matthew Bennett, Rainha Passi, Abdelaziz Beqqali, Neil C Henderson, Joanne C Mountford, Paul R Riley, Chris P Ponting, Nicola Smart, Mairi Brittan, Andrew H Baker

Cardiovasc Res. 2022 Oct; 118(14): 2960–2972. Published online 2022 Feb 25. doi: 10.1093/cvr/cvac023

PMCID:: PMC9648824

Abstract Article PDF–4.6M

Select item 88352425.

EVI1 Promotes the Proliferation and Invasive Properties of Human Head and Neck Squamous Cell Carcinoma Cells

Alexander Michael Grandits, Sophie Bromberger, Gerwin Heller, Barbara Andrea Reinoehl, Erwin Tomasich, Klaudia Schossleitner, Anna Sophie Berghoff, Thorsten Fuereder, Rotraud Wieser

Int J Mol Sci. 2022 Feb; 23(3): 1050. Published online 2022 Jan 19. doi: 10.3390/ijms23031050

PMCID:: PMC8835242

Abstract Article PDF–4.4M

Select item 85509656.

Identification of therapeutic targets of the hijacked super-enhancer complex in EVI1-rearranged leukemia

Sandra Kiehlmeier, Mahmoud-Reza Rafiee, Ali Bakr, Jagoda Mika, Sabrina Kruse, Judith Müller, Sabrina Schweiggert, Carl Herrmann, Gianluca Sigismondo, Peter Schmezer, Jeroen Krijgsveld, Stefan Gröschel

Leukemia. 2021; 35(11): 3127–3138. Published online 2021 Apr 28. doi: 10.1038/s41375-021-01235-z

PMCID:: PMC8550965

Abstract Article PDF–1.1M

Select item 79854987.

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies

Christine Birdwell, Warren Fiskus, Tapan M. Kadia, Courtney D. DiNardo, Christopher P. Mill, Kapil N. Bhalla

Blood Cancer J. 2021 Mar; 11(3): 64. Published online 2021 Mar 22. doi: 10.1038/s41408-021-00457-9

PMCID:: PMC7985498

Abstract Article PDF–811K

Select item 73952838.

EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase

Yusuke Saito, Daisuke Sawa, Mariko Kinoshita, Ai Yamada, Sachiyo Kamimura, Akira Suekane, Honami Ogoh, Hidemasa Matsuo, Souichi Adachi, Takashi Taga, Daisuke Tomizawa, Motomi Osato, Tomoyoshi Soga, Kazuhiro Morishita, Hiroshi Moritake

Haematologica. 2020 Aug; 105(8): 2118–2129. Prepublished online 2019 Oct 24. doi: 10.3324/haematol.2019.225953

PMCID:: PMC7395283

Abstract Article PDF–4.2M

Select item 70380159.

EVI1 as a Marker for Lymph Node Metastasis in HNSCC

Christian Idel, Julika Ribbat-Idel, Patrick Kuppler, Rosemarie Krupar, Anne Offermann, Wenzel Vogel, Dirk Rades, Jutta Kirfel, Barbara Wollenberg, Sven Perner

Int J Mol Sci. 2020 Feb; 21(3): 854. Published online 2020 Jan 28. doi: 10.3390/ijms21030854

PMCID:: PMC7038015

Abstract Article PDF–1.7M

Select item 659642110.

Creatine Kinase Pathway Inhibition Alters GSK3 and WNT Signaling in EVI1-positive AML

Lina Benajiba, Gabriela Alexe, Angela Su, Emmanuel Raffoux, Jean Soulier, Michael T. Hemann, Olivier Hermine, Raphael Itzykson, Kimberly Stegmaier, Alexandre Puissant

Leukemia. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Leukemia. 2019 Mar; 33(3): 800–804. Published online 2018 Nov 2. doi: 10.1038/s41375-018-0291-x

PMCID:: PMC6596421

Article PDF–892K

Select item 637773111.

EVI1 promotes epithelial-to-mesenchymal transition, cancer stem cell features and chemo−/radioresistance in nasopharyngeal carcinoma

Yaoyong Lu, Yingying Liang, Xin Zheng, Xubin Deng, Wendong Huang, Gong Zhang

J Exp Clin Cancer Res. 2019; 38: 82. Published online 2019 Feb 15. doi: 10.1186/s13046-019-1077-3

PMCID:: PMC6377731

Abstract Article PDF–6.4M

Select item 587323812.

MECOM-associated syndrome: a heterogeneous inherited bone marrow failure syndrome with amegakaryocytic thrombocytopenia

Manuela Germeshausen, Phil Ancliff, Jaime Estrada, Markus Metzler, Eva Ponstingl, Horst Rütschle, Dirk Schwabe, Richard H. Scott, Sule Unal, Angela Wawer, Bernward Zeller, Matthias Ballmaier

Blood Adv. 2018 Mar 27; 2(6): 586–596. Published online 2018 Mar 14. doi: 10.1182/bloodadvances.2018016501

PMCID:: PMC5873238

Abstract Article PDF–1.0M

Select item 586542513.

Lethal neonatal bone marrow failure syndrome with multiple congenital abnormalities, including limb defects, due to a constitutional deletion of 3′ MECOM

Lars T. van der Veken, Merel C. Maiburg, Floris Groenendaal, Mariëlle E. van Gijn, Andries C. Bloem, Claudia Erpelinck, Stefan Gröschel, Mathijs A. Sanders, Ruud Delwel, Marc B. Bierings, Arjan Buijs

Haematologica. 2018 Apr; 103(4): e173–e176. doi: 10.3324/haematol.2017.185033

PMCID:: PMC5865425

Article PDF–876K

Select item 583381914.

Ecotropic viral integration site 1 promotes metastasis independent of epithelial mesenchymal transition in colon cancer cells

Kasturi Bala Nayak, I. S. Sajitha, T. R. Santhosh Kumar, Soumen Chakraborty

Cell Death Dis. 2018 Feb; 9(2): 18. Published online 2018 Jan 16. doi: 10.1038/s41419-017-0036-1

PMCID:: PMC5833819

Abstract Article PDF–2.2M

Select item 581036915.

High EVI1 Expression Predicts Poor Outcomes in Adult Acute Myeloid Leukemia Patients with Intermediate Cytogenetic Risk Receiving Chemotherapy

Ya-Zhen Qin, Ting Zhao, Hong-Hu Zhu, Jing Wang, Jin-Song Jia, Yue-Yun Lai, Xiao-Su Zhao, Hong-Xia Shi, Yan-Rong Liu, Hao Jiang, Xiao-Jun Huang, Qian Jiang

Med Sci Monit. 2018; 24: 758–767. Published online 2018 Feb 6. doi: 10.12659/MSM.905903

PMCID:: PMC5810369

Abstract Article PDF–746K

Select item 579228616.

MDS1 and EVI1 complex locus (MECOM): a novel candidate gene for hereditary hematological malignancies

Tim Ripperger, Winfried Hofmann, Jan C. Koch, Katayoon Shirneshan, Detlef Haase, Gerald Wulf, Peter R. Issing, Matthias Karnebogen, Gunnar Schmidt, Bernd Auber, Brigitte Schlegelberger, Thomas Illig, Birgit Zirn, Doris Steinemann

Haematologica. 2018 Feb; 103(2): e55–e58. doi: 10.3324/haematol.2017.178723

PMCID:: PMC5792286

Article PDF–629K

Select item 477640917.

Persistent polyclonal binucleated B-cell lymphocytosis and MECOM gene amplification

Edouard Cornet, Hossein Mossafa, Karine Courel, Jean-François Lesesve, Xavier Troussard

BMC Res Notes. 2016; 9: 138. Published online 2016 Mar 2. doi: 10.1186/s13104-015-1742-3

PMCID:: PMC4776409

Abstract Article PDF–883K

Select item 467842918.

Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia

Tetsuya Niihori, Meri Ouchi-Uchiyama, Yoji Sasahara, Takashi Kaneko, Yoshiko Hashii, Masahiro Irie, Atsushi Sato, Yuka Saito-Nanjo, Ryo Funayama, Takeshi Nagashima, Shin-ichi Inoue, Keiko Nakayama, Keiichi Ozono, Shigeo Kure, Yoichi Matsubara, Masue Imaizumi, Yoko Aoki

Am J Hum Genet. 2015 Dec 3; 97(6): 848–854. Published online 2015 Nov 12. doi: 10.1016/j.ajhg.2015.10.010

PMCID:: PMC4678429

Abstract Article PDF–898K

Select item 461365719.

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid

Birgit Steinmetz, Hubert Hackl, Eva Slabáková, Ilse Schwarzinger, Monika Smějová, Andreas Spittler, Itziar Arbesu, Medhat Shehata, Karel Souček, Rotraud Wieser

Cell Cycle. 2014 Sep 15; 13(18): 2931–2943. Published online 2014 Oct 30. doi: 10.4161/15384101.2014.946869

Correction in:: Cell Cycle. 2015 Jun 3; 14(11): 1759.

PMCID:: PMC4613657

Abstract Article PDF–771K

Select item 452064620.

EVI1, a target gene for amplification at 3q26, antagonizes transforming growth factor-β-mediated growth inhibition in hepatocellular carcinoma

Kohichiroh Yasui, Chika Konishi, Yasuyuki Gen, Mio Endo, Osamu Dohi, Akira Tomie, Tomoko Kitaichi, Nobuhisa Yamada, Naoto Iwai, Taichiro Nishikawa, Kanji Yamaguchi, Michihisa Moriguchi, Yoshio Sumida, Hironori Mitsuyoshi, Shinji Tanaka, Shigeki Arii, Yoshito Itoh

Cancer Sci. 2015 Jul; 106(7): 929–937. Published online 2015 Jun 5. doi: 10.1111/cas.12694

PMCID:: PMC4520646

Abstract Article PDF–1.9M

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PMC Links for Gene (Select 2122) (120)
PMC
ubiquinol-cytochrome c reductase complex assembly factor 1 isoform X4 [Homo sapi...
ubiquinol-cytochrome c reductase complex assembly factor 1 isoform X4 [Homo sapiens]
gi|768017465|ref|XP_011527183.1|

Protein
PREDICTED: Homo sapiens MDS1 and EVI1 complex locus (MECOM), transcript variant ...
PREDICTED: Homo sapiens MDS1 and EVI1 complex locus (MECOM), transcript variant X3, mRNA
gi|2217342536|ref|XM_047447677.1|

Nucleotide

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