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Select item 93389051.

Mechanisms of ion transport regulation by HNF1β in the kidney: beyond transcriptional regulation of channels and transporters

Lotte E. Tholen, Joost G. J. Hoenderop, Jeroen H. F. de Baaij

Pflugers Arch. 2022; 474(8): 901–916. Published online 2022 May 13. doi: 10.1007/s00424-022-02697-5

Correction in:: Pflugers Arch. 2022; 474(8): 917.

PMCID:: PMC9338905

Abstract Article PDF–1.5M

Select item 68838342.

Hepatocyte nuclear factor-1β regulates Wnt signaling through genome-wide competition with β-catenin/lymphoid enhancer binding factor

Siu Chiu Chan, Ying Zhang, Marco Pontoglio, Peter Igarashi

Proc Natl Acad Sci U S A. 2019 Nov 26; 116(48): 24133–24142. Published online 2019 Nov 11. doi: 10.1073/pnas.1909452116

PMCID:: PMC6883834

Abstract Article PDF–2.0M

Select item 53459773.

Polychlorinated biphenyls-153 induces metabolic dysfunction through activation of ROS/NF-κB signaling via downregulation of HNF1b

Hao Wu, Weihua Yu, Fansen Meng, Jie Mi, Jie Peng, Jiangzheng Liu, Xiaodi Zhang, Chunxu Hai, Xin Wang

Redox Biol. 2017 Aug; 12: 300–310. Published online 2017 Mar 7. doi: 10.1016/j.redox.2017.02.026

PMCID:: PMC5345977

Abstract Article PDF–2.4M

Select item 4196024.

Comprehensive search for HNF-1β-regulated genes in mouse hepatoma cells perturbed by transcription regulatory factor-targeted RNAi

Taku Tanaka, Yasuhiro Tomaru, Yuki Nomura, Hisashi Miura, Masanori Suzuki, Yoshihide Hayashizaki

Nucleic Acids Res. 2004; 32(9): 2740–2750. Published online 2004 May 17. doi: 10.1093/nar/gkh597

Correction in:: Nucleic Acids Res. 2004; 32(11): 3511.

PMCID:: PMC419602

Abstract Article PDF–198K

Select item 77629465.

Hepatocyte nuclear factor 1β suppresses canonical Wnt signaling through transcriptional repression of lymphoid enhancer–binding factor 1

Siu Chiu Chan, Sachin S. Hajarnis, Sophia M. Vrba, Vishal Patel, Peter Igarashi

J Biol Chem. 2020 Dec 18; 295(51): 17560–17572. Published online 2020 Oct 13. doi: 10.1074/jbc.RA120.015592

PMCID:: PMC7762946

Abstract Article PDF–2.6M

Select item 61712766.

Mechanism of Fibrosis in HNF1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease

Siu Chiu Chan, Ying Zhang, Annie Shao, Svetlana Avdulov, Jeremy Herrera, Karam Aboudehen, Marco Pontoglio, Peter Igarashi

J Am Soc Nephrol. 2018 Oct; 29(10): 2493–2509. Published online 2018 Aug 10. doi: 10.1681/ASN.2018040437

PMCID:: PMC6171276

Abstract Article

Select item 56199577.

Hepatocyte Nuclear Factor–1β Regulates Urinary Concentration and Response to Hypertonicity

Karam Aboudehen, Lama Noureddine, Patricia Cobo-Stark, Svetlana Avdulov, Shayan Farahani, Micah D. Gearhart, Daniel G. Bichet, Marco Pontoglio, Vishal Patel, Peter Igarashi

J Am Soc Nephrol. 2017 Oct; 28(10): 2887–2900. Published online 2017 May 15. doi: 10.1681/ASN.2016101095

PMCID:: PMC5619957

Abstract Article

Select item 37256728.

Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1β

Yun-Hee Choi, Brian T. McNally, Peter Igarashi

Am J Physiol Renal Physiol. 2013 Jul 1; 305(1): F100–F110. Published online 2013 May 8. doi: 10.1152/ajprenal.00582.2012

PMCID:: PMC3725672

Abstract Article

Select item 30625369.

A mitotic transcriptional switch in polycystic kidney disease

Francisco Verdeguer, Stephanie Le Corre, Evelyne Fischer, Celine Callens, Serge Garbay, Antonia Doyen, Peter Igarashi, Fabiola Terzi, Marco Pontoglio

Nat Med. Author manuscript; available in PMC 2011 Mar 22.

Published in final edited form as: Nat Med. 2010 Jan; 16(1): 106–110. Published online 2009 Dec 6. doi: 10.1038/nm.2068

PMCID:: PMC3062536

Abstract Article PDF–1.2M

Select item 261573510.

HNF-1β Regulates Transcription of the PKD Modifier Gene Kif12

Yimei Gong, Zhendong Ma, Vishal Patel, Evelyne Fischer, Thomas Hiesberger, Marco Pontoglio, Peter Igarashi

J Am Soc Nephrol. 2009 Jan; 20(1): 41–47. doi: 10.1681/ASN.2008020238

PMCID:: PMC2615735

Abstract Article

Select item 256450711.

Mutations in hepatocyte nuclear factor‐1β and their related phenotypes

E L Edghill, C Bingham, S Ellard, A T Hattersley

J Med Genet. 2006 Jan; 43(1): 84–90. Published online 2005 Jun 8. doi: 10.1136/jmg.2005.032854

PMCID:: PMC2564507

Abstract Article PDF–234K

Select item 215444012.

Mutations of HNF-1β inhibit epithelial morphogenesis through dysregulation of SOCS-3

Zhendong Ma, Yimei Gong, Vishal Patel, Courtney M. Karner, Evelyne Fischer, Thomas Hiesberger, Thomas J. Carroll, Marco Pontoglio, Peter Igarashi

Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51): 20386–20391. Published online 2007 Dec 12. doi: 10.1073/pnas.0705957104

PMCID:: PMC2154440

Abstract Article PDF–1.0M

Select item 39106813.

A transcriptional network in polycystic kidney disease

Lionel Gresh, Evelyne Fischer, Andreas Reimann, Myriam Tanguy, Serge Garbay, Xinli Shao, Thomas Hiesberger, Laurence Fiette, Peter Igarashi, Moshe Yaniv, Marco Pontoglio

EMBO J. 2004 Apr 7; 23(7): 1657–1668. Published online 2004 Mar 18. doi: 10.1038/sj.emboj.7600160

PMCID:: PMC391068

Abstract Article PDF–832K

Select item 584486114.

The Role of Tumor Necrosis Factor Alpha in Regulating the Expression of Tamm-Horsfall Protein (Uromodulin) in Thick Ascending Limbs during Kidney Injury

Monique Heitmeier, Ruth McCracken, Radmila Micanovic, Shehnaz Khan, Tarek M. El-Achkar

Am J Nephrol. Author manuscript; available in PMC 2018 Mar 10.

Published in final edited form as: Am J Nephrol. 2014; 40(5): 458–467. Published online 2014 Dec 6. doi: 10.1159/000369836

PMCID:: PMC5844861

Abstract Article PDF–1000K

Select item 335312115.

The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation

Maria-Elena Torres-Padilla, Lucy Richardson, Paulina Kolasinska, Sigolène M. Meilhac, Merlin Verena Luetke-Eversloh, Magdalena Zernicka-Goetz

Dev Biol. Author manuscript; available in PMC 2012 May 16.

Published in final edited form as: Dev Biol. 2007 Sep 1; 309(1): 97–112. Published online 2007 Jul 3. doi: 10.1016/j.ydbio.2007.06.020

PMCID:: PMC3353121

Abstract Article PDF–3.1M

Select item 672230116.

Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis

Evans Quilichini, Mélanie Fabre, Thassadite Dirami, Aline Stedman, Matias De Vas, Ozge Ozguc, Raymond C. Pasek, Silvia Cereghini, Lucie Morillon, Carmen Guerra, Anne Couvelard, Maureen Gannon, Cécile Haumaitre

Cell Mol Gastroenterol Hepatol. 2019; 8(3): 487–511. Published online 2019 Jun 21. doi: 10.1016/j.jcmgh.2019.06.005

PMCID:: PMC6722301

Abstract Article PDF–19M

Select item 590326917.

Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease

Andreas Kompatscher, Jeroen H.F. de Baaij, Karam Aboudehen, Anke P.W.M. Hoefnagels, Peter Igarashi, René J.M. Bindels, Gertjan J.C. Veenstra, Joost G.J. Hoenderop

Kidney Int. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Kidney Int. 2017 Nov; 92(5): 1145–1156. Published online 2017 May 31. doi: 10.1016/j.kint.2017.03.034

PMCID:: PMC5903269

Abstract Article PDF–1.5M

Select item 562662618.

HNF1B loss exacerbates the development of chromophobe renal cell carcinomas

Mianen Sun, Pan Tong, Wen Kong, Baijun Dong, Yiran Huang, Young Park, Lijun Zhou, Xian-De Liu, Zhiyong Ding, Xuesong Zhang, Shanshan Bai, Peter German, Reid Powell, Quan Wang, Xuefei Tong, Nizar M. Tannir, Surena F. Matin, W. Kimryn Rathmell, Gregory N. Fuller, Ian E. McCutcheon, Cheryl L. Walker, Jing Wang, Eric Jonasch

Cancer Res. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Cancer Res. 2017 Oct 1; 77(19): 5313–5326. Published online 2017 Aug 14. doi: 10.1158/0008-5472.CAN-17-0986

PMCID:: PMC5626626

Abstract Article PDF–1.6M

Select item 366044219.

Hnf-1β Transcription Factor Is an Early Hif-1α-Independent Marker of Epithelial Hypoxia and Controls Renal Repair

Stanislas Faguer, Nicolas Mayeur, Audrey Casemayou, Anne-Laure Pageaud, Claire Courtellemont, Claire Cartery, Gilbert J. Fournie, Joost P. Schanstra, Ivan Tack, Jean-Loup Bascands, Dominique Chauveau

PLoS One. 2013; 8(5): e63585. Published online 2013 May 21. doi: 10.1371/journal.pone.0063585

PMCID:: PMC3660442

Abstract Article PDF–1.4M

Select item 323500820.

Cardiovascular defects in a mouse model of HOXA1 syndrome

Nadja Makki, Mario R. Capecchi

Hum Mol Genet. 2012 Jan 1; 21(1): 26–31. Published online 2011 Sep 22. doi: 10.1093/hmg/ddr434

PMCID:: PMC3235008

Abstract Article PDF–358K

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