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Select item 100730931.

TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway

Seul Gi Lee, Jongbeom Chae, Seon Min Woo, Seung Un Seo, Ha-Jeong Kim, Sang-Yeob Kim, David D. Schlaepfer, In-San Kim, Hee-Sae Park, Taeg Kyu Kwon, Ju-Ock Nam

Exp Mol Med. 2023 Mar; 55(3): 520–531. Published online 2023 Mar 1. doi: 10.1038/s12276-023-00947-9

PMCID:: PMC10073093

Abstract Article PDF–4.4M

Select item 90374172.

Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy

Liyuan Wang, Chuchu Zhao, Tao Zheng, Yi Zhang, Hanruo Liu, Xi Wang, Xianling Tang, Baowen Zhao, Ping Liu

Autophagy. 2022; 18(4): 765–782. Published online 2021 Aug 17. doi: 10.1080/15548627.2021.1955469

PMCID:: PMC9037417

Abstract Article PDF–6.5M

Select item 81024893.

Endothelial angiogenic activity and adipose angiogenesis is controlled by extracellular matrix protein TGFBI

Seul Gi Lee, Jin Soo Kim, Ha-Jeong Kim, David D. Schlaepfer, In-San Kim, Ju-Ock Nam

Sci Rep. 2021; 11: 9644. Published online 2021 May 6. doi: 10.1038/s41598-021-88959-1

PMCID:: PMC8102489

Abstract Article PDF–1.7M

Select item 70053004.

Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair

Kohdai Kitamoto, Yukako Taketani, Wataru Fujii, Aya Inamochi, Tetsuya Toyono, Takashi Miyai, Satoru Yamagami, Masahiko Kuroda, Tomohiko Usui, Yasuo Ouchi

Sci Rep. 2020; 10: 2000. Published online 2020 Feb 6. doi: 10.1038/s41598-020-58876-w

PMCID:: PMC7005300

Abstract Article PDF–3.7M

Select item 53625015.

Bigh3 silencing increases retinoblastoma tumor growth in the murine SV40-TAg-Rb model

Nathalie Allaman-Pillet, Anne Oberson, Daniel F Schorderet

Oncotarget. 2017 Feb 28; 8(9): 15490–15506. Published online 2017 Jan 14. doi: 10.18632/oncotarget.14659

PMCID:: PMC5362501

Abstract Article PDF–17M

Select item 47465856.

Lithium inhibits tumor lymphangiogenesis and metastasis through the inhibition of TGFBIp expression in cancer cells

Yong-Sun Maeng, Rina Lee, Boram Lee, Seung-il Choi, Eung Kweon Kim

Sci Rep. 2016; 6: 20739. Published online 2016 Feb 9. doi: 10.1038/srep20739

PMCID:: PMC4746585

Abstract Article PDF–2.6M

Select item 26792767.

Expression patterns of βig-h3 in chondrocyte differentiation during endochondral ossification

Min-Su Han, Jung-Eun Kim, Hong-In Shin, In-San Kim

Exp Mol Med. 2008 Aug 31; 40(4): 453–460. Published online 2008 Aug 31. doi: 10.3858/emm.2008.40.4.453

PMCID:: PMC2679276

Abstract Article PDF–6.2M

Select item 45110018.

Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2

Katsuya Yamazoe, Satoru Yoshida, Miyuki Yasuda, Shin Hatou, Emi Inagaki, Yoko Ogawa, Kazuo Tsubota, Shigeto Shimmura

PLoS One. 2015; 10(7): e0133397. Published online 2015 Jul 21. doi: 10.1371/journal.pone.0133397

PMCID:: PMC4511001

Abstract Article PDF–2.0M

Select item 42864729.

BIGH3 protein and Macrophages in Retinal Endothelial Cell Apoptosis

Albert A. Mondragon, Brandi S. Betts-Obregon, Robert J. Moritz, Kalpana Parvathaneni, Mary M. Navarro, Hong Seok Kim, Chi Fung Lee, Richard G. LeBaron, Reto Asmis, Andrew T. Tsin

Apoptosis. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Apoptosis. 2015 Jan; 20(1): 29–37. doi: 10.1007/s10495-014-1052-6

PMCID:: PMC4286472

Abstract Article PDF–869K

Select item 411941010.

TGFBI (βIG-H3) is a diabetes-risk gene based on mouse and human genetic studies

Bing Han, Hongyu Luo, John Raelson, Jie Huang, Yun Li, Johanne Tremblay, Bing Hu, Shijie Qi, Jiangping Wu

Hum Mol Genet. 2014 Sep 1; 23(17): 4597–4611. Published online 2014 Apr 11. doi: 10.1093/hmg/ddu173

PMCID:: PMC4119410

Abstract Article PDF–804K

Select item 354288311.

βig-h3 Potentiates the Profibrogenic Effect of TGFβ Signaling on Connective Tissue Progenitor Cells Through the Negative Regulation of Master Chondrogenic Genes

Carlos I. Lorda-Diez, Juan A. Montero, Manuel J. Diaz-Mendoza, Juan A. Garcia-Porrero, Juan M. Hurle

Tissue Eng Part A. 2013 Feb; 19(3-4): 448–457. Published online 2012 Oct 24. doi: 10.1089/ten.tea.2012.0188

PMCID:: PMC3542883

Abstract Article PDF–768K

Select item 266430512.

TGFBI deficiency predisposes mice to spontaneous tumor development

Ye Zhang, Gengyun Wen, Genze Shao, Cuidong Wang, Chyuansheng Lin, Hongbo Fang, Adayabalam S. Balajee, Govind Bhagat, Tom K. Hei, Yongliang Zhao

Cancer Res. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Cancer Res. 2009 Jan 1; 69(1): 37–44. doi: 10.1158/0008-5472.CAN-08-1648

PMCID:: PMC2664305

Abstract Article PDF–2.1M

Select item 790933313.

Transforming Growth Factor–induced Protein Promotes NF-κB–mediated Angiogenesis during Postnatal Lung Development

Min Liu, Cristiana Iosef, Shailaja Rao, Racquel Domingo-Gonzalez, Sha Fu, Paige Snider, Simon J. Conway, Gray S. Umbach, Sarah C. Heilshorn, Ruby E. Dewi, Mar J. Dahl, Donald M. Null, Kurt H. Albertine, Cristina M. Alvira

Am J Respir Cell Mol Biol. 2021 Mar; 64(3): 318–330. doi: 10.1165/rcmb.2020-0153OC

PMCID:: PMC7909333

Abstract Article PDF–2.1M

Select item 576027714.

Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies

Ebbe Toftgaard Poulsen, Kasper Runager, Nadia Sukusu Nielsen, Marie V. Lukassen, Karen Thomsen, Paige Snider, Olga Simmons, Henrik Vorum, Simon J. Conway, Jan J. Enghild

FEBS J. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: FEBS J. 2018 Jan; 285(1): 101–114. Published online 2017 Nov 23. doi: 10.1111/febs.14321

PMCID:: PMC5760277

Abstract Article PDF–653K

Select item 1049781515.

Deficiency for scavenger receptors Stabilin‐1 and Stabilin‐2 leads to age‐dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice

Thomas Leibing, Anna Riedel, Yannick Xi, Monica Adrian, Jessica Krzistetzko, Christof Kirkamm, Christof Dormann, Kai Schledzewski, Sergij Goerdt, Cyrill Géraud

Aging Cell. 2023 Sep; 22(9): e13914. Published online 2023 Jun 25. doi: 10.1111/acel.13914

PMCID:: PMC10497815

Abstract Article PDF–15M

Select item 1080579016.

Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity

Fabio Zanini, Xibing Che, Nina E. Suresh, Carsten Knutsen, Paula Klavina, Yike Xie, Racquel Domingo-Gonzalez, Min Liu, Alexander Kum, Robert C. Jones, Stephen R. Quake, Cristina M. Alvira, David N. Cornfield

Sci Rep. 2024; 14: 2033. Published online 2024 Jan 23. doi: 10.1038/s41598-023-50717-w