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Select item 113160681.

Fibroblast growth receptor 1 is regulated by G-quadruplex in metastatic breast cancer

Hang Lin, Muhammad Hassan Safdar, Sarah Washburn, Saeed S. Akhand, Jonathan Dickerhoff, Mitchell Ayers, Marvis Monteiro, Luis Solorio, Danzhou Yang, Michael K. Wendt

Commun Biol. 2024; 7: 963. Published online 2024 Aug 9. doi: 10.1038/s42003-024-06602-x

PMCID:: PMC11316068

Abstract Article PDF–6.3M

Select item 112879992.

Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li

Eur J Histochem. 2024 Jun 27; 68(3): 4048. Published online 2024 Jul 22. doi: 10.4081/ejh.2024.4048

PMCID:: PMC11287999

Abstract Article PDF–830K

Select item 112802133.

Clinical manifestations and spermatogenesis outcomes in Chinese patients with congenital hypogonadotropic hypogonadism caused by inherited or de novo FGFR1 mutations

Yu-Fan Yang, Hai-Lu Ma, Xi Wang, Min Nie, Jiang-Feng Mao, Xue-Yan Wu

Asian J Androl. 2024 Jul-Aug; 26(4): 426–432. Published online 2024 Jan 9. doi: 10.4103/aja202366

PMCID:: PMC11280213

Abstract Article PDF–843K

Select item 110397274.

RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma

Anna M. Jermakowicz, Alison M. Kurimchak, Katherine J. Johnson, Florence Bourgain-Guglielmetti, Simon Kaeppeli, Maurizio Affer, Hari Pradhyumnan, Robert K. Suter, Winston Walters, Maria Cepero, James S. Duncan, Nagi G. Ayad

Sci Rep. 2024; 14: 9284. Published online 2024 Apr 23. doi: 10.1038/s41598-024-60031-8

PMCID:: PMC11039727

Abstract Article PDF–5.5M

Select item 109773535.

How human genetic context can inform pathogenicity classification: FGFR1 variation in idiopathic hypogonadotropic hypogonadism

Wanxue Xu, Lacey Plummer, Stephanie B. Seminara, Ravikumar Balasubramanian, Margaret F. Lippincott

Hum Genet. Author manuscript; available in PMC 2024 Mar 28.

Published in final edited form as: Hum Genet. 2023 Nov; 142(11): 1611–1619. Published online 2023 Oct 7. doi: 10.1007/s00439-023-02601-w

PMCID:: PMC10977353

Abstract Article PDF–661K

Select item 106177676.

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

Florian Malchers, Lucia Nogova, Martijn H.A. van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E. Weeden, Andreas H. Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merkelbach-Bruse, Roopika Menon, Oliver Gautschi, Johannes M. Heuckmann, Elisabeth Brambilla, Marie-Liesse Asselin-Labat, Thorsten Persigehl, John D. Minna, Henning Walczak, Roland T. Ullrich, Matthias Fischer, Hans Christian Reinhardt, Jürgen Wolf, Reinhard Büttner, Martin Peifer, Julie George, Roman K. Thomas

J Clin Invest. 2023 Nov 1; 133(21): e170217. Published online 2023 Nov 1. doi: 10.1172/JCI170217

PMCID:: PMC10617767

Abstract Article PDF–8.7M

Select item 105763437.

FGFR1 variants contributed to families with tooth agenesis

Siyue Yao, Xi Zhou, Min Gu, Chengcheng Zhang, Oliver Bartsch, Barbara Vona, Liwen Fan, Lan Ma, Yongchu Pan

Hum Genomics. 2023; 17: 93. Published online 2023 Oct 13. doi: 10.1186/s40246-023-00539-8

PMCID:: PMC10576343

Abstract Article PDF–4.5M

Select item 95479798.

FGFR1 antibody validation and characterization of FGFR1 protein expression in ER+ breast cancer

Paula I. Gonzalez-Ericsson, Alberto Servetto, Luigi Formisano, Violeta Sánchez, Ingrid A. Mayer, Carlos L. Arteaga, Melinda E. Sanders

Appl Immunohistochem Mol Morphol. Author manuscript; available in PMC 2023 Oct 1.

Published in final edited form as: Appl Immunohistochem Mol Morphol. 2022 Oct 1; 30(9): 600–608. Published online 2022 Sep 12. doi: 10.1097/PAI.0000000000001058

PMCID:: PMC9547979

Abstract Article PDF–1.9M

Select item 89309529.

Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors

Sophie Engelhardt, Felix Behling, Rudi Beschorner, Franziska Eckert, Patricia Kohlhof, Marcos Tatagiba, Ghazaleh Tabatabai, Martin U. Schuhmann, Martin Ebinger, Jens Schittenhelm

J Cancer Res Clin Oncol. 2022; 148(4): 857–866. Published online 2022 Jan 11. doi: 10.1007/s00432-021-03906-x

PMCID:: PMC8930952

Abstract Article PDF–886K

Select item 861614810.

FGFR1 Overexpression Induces Cancer Cell Stemness and Enhanced Akt/Erk-ER Signaling to Promote Palbociclib Resistance in Luminal A Breast Cancer Cells

Qiong Cheng, Zhikun Ma, Yujie Shi, Amanda B. Parris, Lingfei Kong, Xiaohe Yang

Cells. 2021 Nov; 10(11): 3008. Published online 2021 Nov 4. doi: 10.3390/cells10113008

PMCID:: PMC8616148

Abstract Article PDF–10M

Select item 855300811.

FGFR1 Signaling Stimulates Proliferation of Human Mesenchymal Stem Cells by Inhibiting the Cyclin-Dependent Kinase Inhibitors p21^Waf1 and p27^Kip1

Christian Dombrowski, Torben Helledie, Ling Ling, Martin Grünert, Claire A. Canning, C. Michael Jones, James H. Hui, Victor Nurcombe, Andre J. van Wijnen, Simon M. Cool

Stem Cells. Author manuscript; available in PMC 2021 Oct 28.

Published in final edited form as: Stem Cells. 2013 Dec; 31(12): 2724–2736. doi: 10.1002/stem.1514

PMCID:: PMC8553008

Abstract Article PDF–1.6M

Select item 849800212.

Metabolic flexibility maintains proliferation and migration of FGFR signaling–deficient lymphatic endothelial cells

Hongyuan Song, Jie Zhu, Ping Li, Fei Han, Longhou Fang, Pengchun Yu

J Biol Chem. 2021 Oct; 297(4): 101149. Published online 2021 Aug 30. doi: 10.1016/j.jbc.2021.101149

PMCID:: PMC8498002

Abstract Article PDF–2.0M

Select item 839389713.

Novel FGFR1 Variants Are Associated with Congenital Scoliosis

Shengru Wang, Xiran Chai, Zihui Yan, Sen Zhao, Yang Yang, Xiaoxin Li, Yuchen Niu, Guanfeng Lin, Zhe Su, Zhihong Wu, Terry Jianguo Zhang, Nan Wu

Genes (Basel) 2021 Aug; 12(8): 1126. Published online 2021 Jul 24. doi: 10.3390/genes12081126

PMCID:: PMC8393897

Abstract Article PDF–2.2M

Select item 839245514.

FGF1 Fusions with the Fc Fragment of IgG1 for the Assembly of GFPpolygons-Mediated Multivalent Complexes Recognizing FGFRs

Marta Poźniak, Weronika Zarzycka, Natalia Porębska, Agata Knapik, Paulina Marczakiewicz-Perera, Malgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński

Biomolecules. 2021 Aug; 11(8): 1088. Published online 2021 Jul 23. doi: 10.3390/biom11081088

PMCID:: PMC8392455

Abstract Article PDF–4.1M

Select item 829023115.

GZD824 overcomes FGFR1‐V561F/M mutant resistance in vitro and in vivo

Kaili Jiang, Xia Tang, Jing Guo, Rui He, Shingpan Chan, Xiaojuan Song, Zhengchao Tu, Yuting Wang, Xiaomei Ren, Ke Ding, Zhang Zhang

Cancer Med. 2021 Jul; 10(14): 4874–4884. Published online 2021 Jun 10. doi: 10.1002/cam4.4041

PMCID:: PMC8290231

Abstract Article PDF–1.2M

Select item 812130916.

Prognostic value of FGFR1 expression and amplification in patients with HNSCC: A systematic review and meta-analysis

Yao Hu, Li-Sha Ai, Liu-Qing Zhou

PLoS One. 2021; 16(5): e0251202. Published online 2021 May 14. doi: 10.1371/journal.pone.0251202

PMCID:: PMC8121309

Abstract Article PDF–1.1M

Select item 801388317.

FGFR1 Is Associated With Tamoxifen Resistance and Poor Prognosis of ER-Positive Breast Cancers by Suppressing ER Protein Expression

Qing Lv, Shiming Guan, Mingjie Zhu, Hu Huang, Junqiang Wu, Xiaofeng Dai

Technol Cancer Res Treat. 2021; 20: 15330338211004935. Published online 2021 Mar 30. doi: 10.1177/15330338211004935

PMCID:: PMC8013883

Abstract Article PDF–1002K

Select item 788158418.

FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1

Silvana Mouron, Luis Manso, Eduardo Caleiras, Jose L. Rodriguez-Peralto, Oscar M. Rueda, Carlos Caldas, Ramon Colomer, Miguel Quintela-Fandino, Maria J. Bueno

Breast Cancer Res. 2021; 23: 21. Published online 2021 Feb 12. doi: 10.1186/s13058-021-01398-8