U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from Gene

Items: 1 to 20 of 79

1.
Cytosolic 5′-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway
Rossana Pesi, Simone Allegrini, Mercedes Garcia-Gil, Lucia Piazza, Roberta Moschini, Lars Petter Jordheim, Marcella Camici, Maria Grazia Tozzi
Int J Mol Sci. 2021 Jul; 22(13): 7004. Published online 2021 Jun 29. doi: 10.3390/ijms22137004
PMCID:
PMC8268954
ArticlePDF–3.0M
2.
Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia
Chuang Jiang, Wenjian Yang, Takaya Moriyama, Chengcheng Liu, Colton Smith, Wentao Yang, Maoxiang Qian, Ziping Li, Morten Tulstrup, Kjeld Schmiegelow, Kristine R. Crews, Hui Zhang, Ching-Hon Pui, William Evans, Mary Relling, Smita Bhatia, Jun J. YangP
Clin Pharmacol Ther. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Jun; 109(6): 1538–1545. Published online 2020 Nov 24. doi: 10.1002/cpt.2095
PMCID:
PMC8081740
ArticlePDF–716K
3.
Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia
Malwine J. Barz, Jana Hof, Stefanie Groeneveld-Krentz, Jui Wan Loh, Annabell Szymansky, Kathy Astrahantseff, Arend von Stackelberg, Hossein Khiabanian, Adolfo A. Ferrando, Cornelia Eckert, Renate Kirschner-Schwabe
Blood. 2020 Mar 19; 135(12): 921–933. Prepublished online 2020 Jan 22. doi: 10.1182/blood.2019002499
PMCID:
PMC7218751
Article
4.
The rs11191580 variant of the NT5C2 gene is associated with schizophrenia and symptom severity in a South Chinese Han population: evidence from GWAS
Zhen Li, Juan Jiang, Jianxiong Long, Weijun Ling, Guifeng Huang, Xiaojing Guo, Li Su
Braz J Psychiatry. 2017; 39(2): 104–109. Published online 2016 Nov 24. doi: 10.1590/1516-4446-2016-1958
PMCID:
PMC7111442
ArticlePDF–76K
5.
Mechanisms of NT5C2-mediated thiopurine resistance in acute lymphoblastic leukemia
Takaya Moriyama, Shuguang Liu, Jing Li, Julia Meyer, Xujie Zhao, Wentao Yang, Youming Shao, Richard Heath, Aleš Hnízda, William L Carroll, Jun J Yang
Mol Cancer Ther. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Mol Cancer Ther. 2019 Oct; 18(10): 1887–1895. Published online 2019 Jul 29. doi: 10.1158/1535-7163.MCT-18-1112
PMCID:
PMC6774896
ArticlePDF–1.5M
6.
Structure and mechanisms of NT5C2 mutations driving thiopurine resistance in relapsed lymphoblastic leukemia
Chelsea L. Dieck, Gannie Tzoneva, Farhad Forouhar, Zachary Carpenter, Alberto Ambesi-Impiombato, Marta Sánchez-Martín, Renate Kirschner-Schwabe, Scott Lew, Jayaraman Seetharaman, Liang Tong, Adolfo A. Ferrando
Cancer Cell. Author manuscript; available in PMC 2019 Jul 9.
Published in final edited form as: Cancer Cell. 2018 Jul 9; 34(1): 136–147.e6. doi: 10.1016/j.ccell.2018.06.003
PMCID:
PMC6049837
ArticlePDF–2.0M
7.
NT5C2 novel splicing variant expands the phenotypic spectrum of Spastic Paraplegia (SPG45): case report of a new member of thin corpus callosum SPG-Subgroup
Mahmoud F. Elsaid, Khalid Ibrahim, Nader Chalhoub, Ahmed Elsotouhy, Noora El Mudehki, Alice Abdel Aleem
BMC Med Genet. 2017; 18: 33. Published online 2017 Mar 21. doi: 10.1186/s12881-017-0395-6
PMCID:
PMC5359868
ArticlePDF–775K
8.
Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia
Aleš Hnízda, Jana Škerlová, Milan Fábry, Petr Pachl, Martina Šinalová, Lukáš Vrzal, Petr Man, Petr Novák, Pavlína Řezáčová, Václav Veverka
BMC Biol. 2016; 14: 91. Published online 2016 Oct 19. doi: 10.1186/s12915-016-0313-y
PMCID:
PMC5070119
ArticlePDF–3.6M
9.
Relapse specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
Julia A. Meyer, Jinhua Wang, Laura E. Hogan, Jun J. Yang, Smita Dandekar, Jay P. Patel, Zuojian Tang, Paul Zumbo, Sheng Li, Jiri Zavadil, Ross L. Levine, Timothy Cardozo, Stephen P. Hunger, Elizabeth A. Raetz, William E. Evans, Debra J. Morrison, Christopher E. Mason, William L. Carroll
Nat Genet. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: Nat Genet. 2013 Mar; 45(3): 290–294. Published online 2013 Feb 3. doi: 10.1038/ng.2558
PMCID:
PMC3681285
ArticlePDF–504K
10.
TRIM22 orchestrates the proliferation of GBMs and the benefits of TMZ by coordinating the modification and degradation of RIG-I
Xiaowei Fei, Xiuquan Wu, Ya-Nan Dou, Kai Sun, Qingdong Guo, Lei Zhang, Sanzhong Li, Jialiang Wei, Yu Huan, Xin He, Zhou Fei
Mol Ther Oncolytics. 2022 Sep 15; 26: 413–428. Published online 2022 Aug 25. doi: 10.1016/j.omto.2022.08.007
PMCID:
PMC9465028
ArticlePDF–7.2M
11.
The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells
Rodrigo R.R. Duarte, Nathaniel D. Bachtel, Marie-Caroline Côtel, Sang H. Lee, Sashika Selvackadunco, Iain A. Watson, Gary A. Hovsepian, Claire Troakes, Gerome D. Breen, Douglas F. Nixon, Robin M. Murray, Nicholas J. Bray, Ioannis Eleftherianos, Anthony C. Vernon, Timothy R. Powell, Deepak P. Srivastava
Biol Psychiatry. 2019 Jul 15; 86(2): 120–130. doi: 10.1016/j.biopsych.2019.03.977
PMCID:
PMC6614717
Article
12.
Cytosolic 5’-Nucleotidase II Interacts with the Leucin Rich Repeat of NLR Family Member Ipaf
Federico Cividini, Maria Grazia Tozzi, Alvaro Galli, Rossana Pesi, Marcella Camici, Charles Dumontet, Lars Petter Jordheim, Simone Allegrini
PLoS One. 2015; 10(3): e0121525. Published online 2015 Mar 26. doi: 10.1371/journal.pone.0121525
PMCID:
PMC4374842
ArticlePDF–3.2M
13.
Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL
Gannie Tzoneva, Arianne Perez Garcia, Zachary Carpenter, Hossein Khiabanian, Valeria Tosello, Maddalena Allegretta, Elisabeth Paietta, Janis Racevskis, Jacob M. Rowe, Martin S. Tallman, Maddalena Paganin, Giuseppe Basso, Jana Hof, Renate Kirschner-Schwabe, Teresa Palomero, Raul Rabadan, Adolfo Ferrando
Nat Med. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: Nat Med. 2013 Mar; 19(3): 368–371. Published online 2013 Feb 3. doi: 10.1038/nm.3078
PMCID:
PMC3594483
ArticlePDF–631K
14.
NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells
Shinpei Somazu, Yoichi Tanaka, Minori Tamai, Atsushi Watanabe, Keiko Kagami, Masako Abe, Daisuke Harama, Tamao Shinohara, Koshi Akahane, Kumiko Goi, Kanji Sugita, Takaya Moriyama, Jun Yang, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto, Junko Takita, Takeshi Inukai
J Cell Mol Med. 2021 Nov; 25(22): 10521–10533. Published online 2021 Oct 12. doi: 10.1111/jcmm.16981
PMCID:
PMC8581340
ArticlePDF–1.5M
15.
Bovine cytosolic IMP/GMP-specific 5'-nucleotidase: cloning and expression of active enzyme in Escherichia coli.
S Allegrini, R Pesi, M G Tozzi, C J Fiol, R B Johnson, S Eriksson
Biochem J. 1997 Dec 1; 328(Pt 2): 483–487. doi: 10.1042/bj3280483
PMCID:
PMC1218945
SummaryPDF–612K
16.
Associations between Gene-Gene Interaction and Overweight/Obesity of 12-Month-Old Chinese Infants
Hong Mei, Baoming Yin, Wenhong Yang, Jingli Zhang, Hongyan Lu, Xiaobin Qi, Wenhua Mei, Hongzhong Zhang, Jianduan Zhang
Biomed Res Int. 2022; 2022: 1499454. Published online 2022 Mar 7. doi: 10.1155/2022/1499454
PMCID:
PMC8920651
ArticlePDF–470K
17.
NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes
Yng-Tay Chen, Wei-De Lin, Wen-Ling Liao, Ya-Ching Tsai, Jiunn-Wang Liao, Fuu-Jen Tsai
Sci Rep. 2020; 10: 16087. Published online 2020 Sep 30. doi: 10.1038/s41598-020-71336-9
Correction in:
Sci Rep. 2021; 11: 6961.
PMCID:
PMC7527562
ArticlePDF–1.6M
18.
Genome‐wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis‐regulation of BORCS7, AS3MT, and NT5C2 in the human brain
Rodrigo R. R. Duarte, Claire Troakes, Matthew Nolan, Deepak P. Srivastava, Robin M. Murray, Nicholas J. Bray
Am J Med Genet B Neuropsychiatr Genet. 2016 Sep; 171(6): 806–814. Published online 2016 Mar 22. doi: 10.1002/ajmg.b.32445
PMCID:
PMC4988385
ArticlePDF–725K
19.
Identification of Drosophila and Human 7-Methyl GMP-specific Nucleotidases
Juliane Buschmann, Bodo Moritz, Mandy Jeske, Hauke Lilie, Angelika Schierhorn, Elmar Wahle
J Biol Chem. 2013 Jan 25; 288(4): 2441–2451. Published online 2012 Dec 5. doi: 10.1074/jbc.M112.426700
PMCID:
PMC3554913
ArticlePDF–2.1M
20.
GENOME-WIDE ASSOCIATION STUDY META-ANALYSIS REVEALS TRANS-ETHNIC REPLICATION OF MEAN ARTERIAL AND PULSE PRESSURE LOCI
Tanika N. Kelly, Fumihiko Takeuchi, Yasuharu Tabara, Todd L. Edwards, Young Jin Kim, Peng Chen, Huaixing Li, Ying Wu, Chi-Fan Yang, Yonghong Zhang, Dongfeng Gu, Tomohiro Katsuya, Takayoshi Ohkubo, Yu-Tang Gao, Min Jin Go, Yik Ying Teo, Ling Lu, Nanette R. Lee, Li-Ching Chang, Hao Peng, Qi Zhao, Eitaro Nakashima, Yoshikuni Kita, Xiao-Ou Shu, Nam Hee Kim, E Shyong Tai, Yiqin Wang, Linda S. Adair, Chien-Hsiun Chen, Shihiu Zhang, Changwei Li, Toru Nabika, Satoshi Umemura, Qiuyin Cai, Yoon Shin Cho, Tien Yin Wong, Jingwen Zhu, Jer-Yuarn Wu, Xin Gao, James E. Hixson, Hui Cai, Juyoung Lee, Ching-Yu Cheng, Dabeeru C. Rao, Yong-Bing Xiang, Myeong-Chan Cho, Bok-Ghee Han, Aili Wang, Fuu-Jen Tsai, Karen Mohlke, Xu Lin, Mohammad Kamran Ikram, Jong-Young Lee, Wei Zheng, Miki Tetsuro, Norihiro Kato, Jiang He
Hypertension. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: Hypertension. 2013 Nov; 62(5): 853–859. Published online 2013 Sep 3. doi: 10.1161/HYPERTENSIONAHA.113.01148
PMCID:
PMC3972802
ArticlePDF–1.2M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center