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Items: 1 to 20 of 80

1.
Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance
Fei Li, Yizhe Wang, Inah Hwang, Ja-Young Jang, Libo Xu, Zhong Deng, Eun Young Yu, Yiming Cai, Caizhi Wu, Zhenbo Han, Yu-Han Huang, Xiangao Huang, Ling Zhang, Jun Yao, Neal F. Lue, Paul M. Lieberman, Haoqiang Ying, Jihye Paik, Hongwu Zheng
Nat Commun. 2023; 14: 1756. Published online 2023 Mar 29. doi: 10.1038/s41467-023-37480-2
PMCID:
PMC10060224
AbstractArticlePDF–3.7M
2.
Histone H3K36me2 demethylase KDM2A promotes bladder cancer progression through epigenetically silencing RARRES3
Bing Lu, Jiatian Wei, Houhong Zhou, Jie Chen, Yuqing Li, Liefu Ye, Wei Zhao, Song Wu
Cell Death Dis. 2022 Jun; 13(6): 547. Published online 2022 Jun 13. doi: 10.1038/s41419-022-04983-7
PMCID:
PMC9192503
AbstractArticlePDF–5.0M
3.
Expression pattern and regulatory effect of lysine-specific demethylase 2A gene in clear cell renal cell carcinoma
Jiannan Wang, Tan Li, Xiang Li, Yixia Zhang, Xuemei Wang
BMC Urol. 2021; 21: 108. Published online 2021 Aug 14. doi: 10.1186/s12894-021-00867-8
PMCID:
PMC8364110
AbstractArticlePDF–1.2M
4.
Lysine demethylase 2A expression in cancer-associated fibroblasts promotes breast tumour growth
Jing-Yi Chen, Chien-Feng Li, You-Syuan Lai, Wen-Chun Hung
Br J Cancer. 2021 Jan 19; 124(2): 484–493. Published online 2020 Oct 7. doi: 10.1038/s41416-020-01112-z
PMCID:
PMC7852571
AbstractArticlePDF–3.5M
5.
Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription
Yuji Tanaka, Hideru Obinata, Akimitsu Konishi, Noriyuki Yamagiwa, Makoto Tsuneoka
Cells. 2020 Oct; 9(10): 2266. Published online 2020 Oct 10. doi: 10.3390/cells9102266
PMCID:
PMC7601038
AbstractArticlePDF–1.0M
6.
Lysine-specific demethylase 2A enhances binding of various nuclear factors to CpG-rich genomic DNAs by action of its CXXC-PHD domain
Shiro Iuchi, Joao A. Paulo
Sci Rep. 2019; 9: 5496. Published online 2019 Apr 2. doi: 10.1038/s41598-019-41896-6
PMCID:
PMC6445129
AbstractArticlePDF–3.6M
7.
Lysine demethylase 2A promotes the progression of ovarian cancer by regulating the PI3K pathway and reversing epithelial-mesenchymal transition
Dan-Hua Lu, Jiang Yang, Li-Kun Gao, Jie Min, Jian-Ming Tang, Ming Hu, Yang Li, Su-Ting Li, Jing Chen, Li Hong
Oncol Rep. 2019 Feb; 41(2): 917–927. Published online 2018 Nov 27. doi: 10.3892/or.2018.6888
PMCID:
PMC6313075
AbstractArticlePDF–1.8M
8.
Targeting glioma stem‐like cell survival and chemoresistance through inhibition of lysine‐specific histone demethylase KDM2B
Mikkel Staberg, Rikke Darling Rasmussen, Signe Regner Michaelsen, Henriette Pedersen, Kamilla Ellermann Jensen, Mette Villingshøj, Jane Skjoth‐Rasmussen, Jannick Brennum, Kristoffer Vitting‐Seerup, Hans Skovgaard Poulsen, Petra Hamerlik
Mol Oncol. 2018 Mar; 12(3): 406–420. Published online 2018 Feb 12. doi: 10.1002/1878-0261.12174
PMCID:
PMC5830623
AbstractArticlePDF–2.3M
9.
Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1
Jing-Yi Chen, Chien-Feng Li, Pei-Yi Chu, You-Syuan Lai, Chung-Hsing Chen, Shih Sheng Jiang, Ming-Feng Hou, Wen-Chun Hung
Oncotarget. 2016 May 10; 7(19): 27689–27710. Published online 2016 Mar 25. doi: 10.18632/oncotarget.8381
PMCID:
PMC5053681
AbstractArticlePDF–9.0M
10.
Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer
Hui Liu, Lanxin Liu, Andreana Holowatyj, Yuanyuan Jiang, Zeng-Quan Yang
Mol Carcinog. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Mol Carcinog. 2016 May; 55(5): 977–990. Published online 2015 Jul 24. doi: 10.1002/mc.22341
PMCID:
PMC4724550
AbstractArticlePDF–1.3M
11.
A Photoreactive Small-Molecule Probe for 2-Oxoglutarate Oxygenases
Dante Rotili, Mikael Altun, Akane Kawamura, Alexander Wolf, Roman Fischer, Ivanhoe K. H. Leung, Mukram M. Mackeen, Ya-min Tian, Peter J. Ratcliffe, Antonello Mai, Benedikt M. Kessler, Christopher J. Schofield
Chem Biol. Author manuscript; available in PMC 2015 Dec 16.
Published in final edited form as: Chem Biol. 2011 May 27; 18(5): 642–654. doi: 10.1016/j.chembiol.2011.03.007
PMCID:
PMC4681097
AbstractArticlePDF–2.6M
12.
Mild Glucose Starvation Induces KDM2A-Mediated H3K36me2 Demethylation through AMPK To Reduce rRNA Transcription and Cell Proliferation
Yuji Tanaka, Hirohisa Yano, Sachiko Ogasawara, Sho-ichi Yoshioka, Hiromi Imamura, Kengo Okamoto, Makoto Tsuneoka
Mol Cell Biol. 2015 Dec; 35(24): 4170–4184. Prepublished online 2015 Sep 28. Published online 2015 Nov 17. doi: 10.1128/MCB.00579-15
PMCID:
PMC4648824
AbstractArticlePDF–1.1M
13.
Lysine-specific demethylase 2A (KDM2A) normalizes human embryonic stem cell derived keratinocytes
Shiro Iuchi, Howard Green
Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24): 9442–9447. Published online 2012 May 25. doi: 10.1073/pnas.1206176109
PMCID:
PMC3386085
AbstractArticlePDF–707K
14.
JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation
Yuji Tanaka, Kengo Okamoto, Kwesi Teye, Toshiyuki Umata, Noriyuki Yamagiwa, Yutaka Suto, Yi Zhang, Makoto Tsuneoka
EMBO J. 2010 May 5; 29(9): 1510–1522. Published online 2010 Apr 8. doi: 10.1038/emboj.2010.56
PMCID:
PMC2876952
AbstractArticlePDF–1.7M
15.
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state
David Frescas, Daniele Guardavaccaro, Hiroyuki Kato, Andrey Poleshko, Richard A. Katz, Michele Pagano
Cell Cycle. Author manuscript; available in PMC 2009 May 15.
Published in final edited form as: Cell Cycle. 2008 Nov 15; 7(22): 3539–3547. Published online 2008 Nov 24. doi: 10.4161/cc.7.22.7062
PMCID:
PMC2636745
AbstractArticlePDF–3.7M
16.
Up-regulation of miR-663a inhibits the cancer stem cell-like properties of glioma via repressing the KDM2A-mediated TGF-β/SMAD signaling pathway
Lei Wang, Bojuan Lang, Youdong Zhou, Jinyang Ma, Keqi Hu
Cell Cycle. 2021; 20(19): 1935–1952. Published online 2021 Aug 23. doi: 10.1080/15384101.2021.1966962
PMCID:
PMC8565824
AbstractArticlePDF–4.4M
17.
Demethylation of SFRP2 by histone demethylase KDM2A regulated osteo‐/dentinogenic differentiation of stem cells of the apical papilla
Guoxia Yu, Jinsong Wang, Xiao Lin, Shu Diao, Yu Cao, Rui Dong, Liping Wang, Songlin Wang, Zhipeng Fan
Cell Prolif. 2016 Jun; 49(3): 330–340. Published online 2016 Apr 13. doi: 10.1111/cpr.12256
PMCID:
PMC6496193
AbstractArticlePDF–1.0M
18.
MicroRNA-3666 suppresses the growth and migration of glioblastoma cells by targeting KDM2A
Taotao Shou, Huyin Yang, Jia Lv, Dai Liu, Xiaoyang Sun
Mol Med Rep. 2019 Feb; 19(2): 1049–1055. Published online 2018 Nov 27. doi: 10.3892/mmr.2018.9698
PMCID:
PMC6323202
AbstractArticlePDF–1.0M
19.
A demethylation deficient isoform of the lysine demethylase KDM2A interacts with pericentromeric heterochromatin in an HP1a-dependent manner
Dijana Lađinović, Jitka Novotná, Soňa Jakšová, Ivan Raška, Tomáš Vacík
Nucleus. 2017; 8(5): 563–572. Published online 2017 Aug 17. doi: 10.1080/19491034.2017.1342915
Correction in:
Nucleus. 2018; 9(1): 291.
PMCID:
PMC5703260
AbstractArticlePDF–869K
20.
Expanding the Molecular Signature of Ossifying Fibromyxoid Tumors with 2 Novel Gene Fusions: CREBBP-BCORL1 and KDM2A-WWTR1
Yu-Chien Kao, Yun-Shao Sung, Lei Zhang, Chun-Liang Chen, Shih-Chiang Huang, Cristina R. Antonescu
Genes Chromosomes Cancer. Author manuscript; available in PMC 2017 Aug 24.
Published in final edited form as: Genes Chromosomes Cancer. 2017 Jan; 56(1): 42–50. Published online 2016 Aug 26. doi: 10.1002/gcc.22400
PMCID:
PMC5570549
AbstractArticlePDF–841K

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