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Items: 1 to 20 of 77

1.
Biogenesis of secretory immunoglobulin M requires intermediate non‐native disulfide bonds and engagement of the protein disulfide isomerase ERp44
Chiara Giannone, Maria Rita Chelazzi, Andrea Orsi, Tiziana Anelli, Tuan Nguyen, Johannes Buchner, Roberto Sitia
EMBO J. 2022 Feb 1; 41(3): e108518. Published online 2021 Dec 27. doi: 10.15252/embj.2021108518
PMCID:
PMC8804937
AbstractArticlePDF–2.6M
2.
Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma
Tian Xia, Hui Tian, Kaiwen Zhang, Siyu Zhang, Wenhui Chen, Si Shi, Yiwen You
BMC Cancer. 2021; 21: 1003. Published online 2021 Sep 8. doi: 10.1186/s12885-021-08712-9
PMCID:
PMC8424889
AbstractArticlePDF–3.8M
3.
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway
Satoshi Watanabe, Yuta Amagai, Sara Sannino, Tiziana Tempio, Tiziana Anelli, Manami Harayama, Shoji Masui, Ilaria Sorrentino, Momo Yamada, Roberto Sitia, Kenji Inaba
Nat Commun. 2019; 10: 603. Published online 2019 Feb 5. doi: 10.1038/s41467-019-08429-1
PMCID:
PMC6363758
AbstractArticlePDF–3.4M
4.
Progressive quality control of secretory proteins in the early secretory compartment by ERp44
Sara Sannino, Tiziana Anelli, Margherita Cortini, Shoji Masui, Massimo Degano, Claudio Fagioli, Kenji Inaba, Roberto Sitia
J Cell Sci. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: J Cell Sci. 2014 Oct 1; 127(19): 4260–4269. Published online 2014 Aug 5. doi: 10.1242/jcs.153239
PMCID:
PMC4251952
AbstractArticlePDF–2.0M
5.
A pH-Regulated Quality Control Cycle for Surveillance of Secretory Protein Assembly
Stefano Vavassori, Margherita Cortini, Shoji Masui, Sara Sannino, Tiziana Anelli, Imma R. Caserta, Claudio Fagioli, Maria F. Mossuto, Arianna Fornili, Eelco van Anken, Massimo Degano, Kenji Inaba, Roberto Sitia
Mol Cell. 2013 Jun 27; 50(6): 783–792. doi: 10.1016/j.molcel.2013.04.016
PMCID:
PMC3699783
AbstractArticle
6.
Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail
Likun Wang, Lei Wang, Stefano Vavassori, Shengjian Li, Huimin Ke, Tiziana Anelli, Massimo Degano, Riccardo Ronzoni, Roberto Sitia, Fei Sun, Chih-chen Wang
EMBO Rep. 2008 Jul; 9(7): 642–647. Published online 2008 Jun 13. doi: 10.1038/embor.2008.88
PMCID:
PMC2475331
AbstractArticlePDF–301K
7.
Protein tyrosine phosphatase receptor type O (PTPRO) knockdown enhances the proliferative, invasive and angiogenic activities of trophoblast cells by suppressing ER resident protein 44 (ERp44) expression in preeclampsia
Yang Yang, Xiaoxia Qiu, Fang Wang
Bioengineered. 2021; 12(2): 9561–9574. Published online 2021 Dec 11. doi: 10.1080/21655979.2021.1997561
PMCID:
PMC8810010
AbstractArticlePDF–4.7M
8.
GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake
Yicong Li, Coedy Hadden, Preeti Singh, Charles P. Mercado, Pamela Murphy, Nafisa K. Dajani, Curtis L. Lowery, Drucilla J. Roberts, Luc Maroteaux, Fusun Kilic
Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52): E5697–E5705. Published online 2014 Dec 15. doi: 10.1073/pnas.1416675112
PMCID:
PMC4284607
AbstractArticlePDF–1.4M
9.
Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44
Tiziana Anelli, Massimo Alessio, Angela Bachi, Leda Bergamelli, Gloria Bertoli, Serena Camerini, Alexandre Mezghrani, Elena Ruffato, Thomas Simmen, Roberto Sitia
EMBO J. 2003 Oct 1; 22(19): 5015–5022. doi: 10.1093/emboj/cdg491
PMCID:
PMC204474
AbstractArticlePDF–237K
10.
Secretory kinase Fam20C tunes endoplasmic reticulum redox state via phosphorylation of Ero1α
Jianchao Zhang, Qinyu Zhu, Xi'e Wang, Jiaojiao Yu, Xinxin Chen, Jifeng Wang, Xi Wang, Junyu Xiao, Chih‐chen Wang, Lei Wang
EMBO J. 2018 Jul 13; 37(14): e98699. Published online 2018 Jun 1. doi: 10.15252/embj.201798699
PMCID:
PMC6043849
AbstractArticlePDF–4.5M
11.
Dynamic Regulation of Ero1α and Peroxiredoxin 4 Localization in the Secretory Pathway
Taichi Kakihana, Kazutaka Araki, Stefano Vavassori, Shun-ichiro Iemura, Margherita Cortini, Claudio Fagioli, Tohru Natsume, Roberto Sitia, Kazuhiro Nagata
J Biol Chem. 2013 Oct 11; 288(41): 29586–29594. Published online 2013 Aug 26. doi: 10.1074/jbc.M113.467845
PMCID:
PMC3795256
AbstractArticlePDF–2.2M
12.
Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis
Tiziana Anelli, Stefania Ceppi, Leda Bergamelli, Margherita Cortini, Silvia Masciarelli, Caterina Valetti, Roberto Sitia
EMBO J. 2007 Oct 3; 26(19): 4177–4188. Published online 2007 Sep 6. doi: 10.1038/sj.emboj.7601844
PMCID:
PMC2230840
AbstractArticlePDF–445K
13.
ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family
Tiziana Anelli, Massimo Alessio, Alexandre Mezghrani, Thomas Simmen, Fabio Talamo, Angela Bachi, Roberto Sitia
EMBO J. 2002 Feb 15; 21(4): 835–844. doi: 10.1093/emboj/21.4.835
PMCID:
PMC125352
AbstractArticlePDF–447K
14.
The human protein disulfide isomerase gene family
James J Galligan, Dennis R Petersen
Hum Genomics. 2012; 6(1): 6. Published online 2012 Jul 5. doi: 10.1186/1479-7364-6-6
PMCID:
PMC3500226
AbstractArticlePDF–852K
15.
Genome-wide association study of preeclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort
Linlu Zhao, Michael B. Bracken, Andrew T. DeWan
Ann Hum Genet. Author manuscript; available in PMC 2014 Jul 30.
Published in final edited form as: Ann Hum Genet. 2013 Jul; 77(4): 277–287. Published online 2013 Apr 2. doi: 10.1111/ahg.12021
PMCID:
PMC3740040
AbstractArticlePDF–151K
16.
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care
Clemens Gutmann, Kaloyan Takov, Sean A. Burnap, Bhawana Singh, Hashim Ali, Konstantinos Theofilatos, Ella Reed, Maria Hasman, Adam Nabeebaccus, Matthew Fish, Mark JW. McPhail, Kevin O’Gallagher, Lukas E. Schmidt, Christian Cassel, Marieke Rienks, Xiaoke Yin, Georg Auzinger, Salvatore Napoli, Salma F. Mujib, Francesca Trovato, Barnaby Sanderson, Blair Merrick, Umar Niazi, Mansoor Saqi, Konstantina Dimitrakopoulou, Rafael Fernández-Leiro, Silke Braun, Romy Kronstein-Wiedemann, Katie J. Doores, Jonathan D. Edgeworth, Ajay M. Shah, Stefan R. Bornstein, Torsten Tonn, Adrian C. Hayday, Mauro Giacca, Manu Shankar-Hari, Manuel Mayr
Nat Commun. 2021; 12: 3406. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23494-1
PMCID:
PMC8184784
AbstractArticlePDF–7.5M
17.
Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality
Arti T. Navare, Fred D. Mast, Jean Paul Olivier, Thierry Bertomeu, Maxwell L. Neal, Lindsay N. Carpp, Alexis Kaushansky, Jasmin Coulombe-Huntington, Mike Tyers, John D. Aitchison
J Cell Biol. 2022 Nov 7; 221(11): e202011050. Published online 2022 Oct 28. doi: 10.1083/jcb.202011050
PMCID:
PMC9623979
AbstractArticlePDF–3.7M
18.
EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired
Marioara Chiritoiu, Gabriela N. Chiritoiu, Cristian V. A. Munteanu, Florin Pastrama, N. Erwin Ivessa, Stefana M. Petrescu
Int J Mol Sci. 2020 May; 21(10): 3468. Published online 2020 May 14. doi: 10.3390/ijms21103468
PMCID:
PMC7279049
AbstractArticlePDF–12M
19.
A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair
Patrick Herr, Cecilia Lundin, Bastiaan Evers, Daniel Ebner, Christina Bauerschmidt, Guy Kingham, Timea Palmai-Pallag, Oliver Mortusewicz, Oliver Frings, Erik Sonnhammer, Thomas Helleday
Cell Discov. 2015; 1: 15034. Published online 2015 Dec 1. doi: 10.1038/celldisc.2015.34
PMCID:
PMC4860774
AbstractArticlePDF–4.1M
20.
Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress
Jiaojiao Yu, Tao Li, Yu Liu, Xi Wang, Jianchao Zhang, Xi'e Wang, Guizhi Shi, Jizhong Lou, Likun Wang, Chih‐chen Wang, Lei Wang
EMBO J. 2020 May 18; 39(10): e103841. Published online 2020 Mar 9. doi: 10.15252/embj.2019103841
PMCID:
PMC7232009
AbstractArticlePDF–5.5M

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