PMC Links for Gene (Select 23097) - PMC

Finn-Ole Paulsen, Christian Idel, Julika Ribbat-Idel, Patrick Kuppler, Luise Klapper, Dirk Rades, Karl-Ludwig Bruchhage, Barbara Wollenberg, Johannes Brägelmann, Sven Perner, Anne Offermann

Int J Mol Sci. 2020 Aug; 21(15): 5508. Published online 2020 Jul 31. doi: 10.3390/ijms21155508

PMCID:: PMC7432755

Abstract Article PDF–4.0M

Select item 54728324.

A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response

K. Audrey Audetat, Matthew D. Galbraith, Aaron T. Odell, Thomas Lee, Ahwan Pandey, Joaquin M. Espinosa, Robin D. Dowell, Dylan J. Taatjes

Mol Cell Biol. 2017 Jul 1; 37(13): e00626-16. Prepublished online 2017 Apr 17. Published online 2017 Jun 15. doi: 10.1128/MCB.00626-16

PMCID:: PMC5472832

Abstract Article PDF–5.4M

Select item 104151395.

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins

Mengqian Chen, Jing Li, Li Zhang, Lili Wang, Chen Cheng, Hao Ji, Serena Altilia, Xiaokai Ding, Guoshuai Cai, Diego Altomare, Michael Shtutman, Stephanie D Byrum, Samuel G Mackintosh, Alexey Feoktistov, Nataliya Soshnikova, Vladislav A Mogila, Victor Tatarskiy, Maksim Erokhin, Darya Chetverina, Angga Prawira, Yi Ni, Stephan Urban, Campbell McInnes, Eugenia V Broude, Igor B Roninson

Nucleic Acids Res. 2023 Aug 11; 51(14): 7288–7313. Published online 2023 Jun 28. doi: 10.1093/nar/gkad538

PMCID:: PMC10415139

Abstract Article PDF–11M

Select item 73545996.

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection

Molly Butler, Nunya Chotiwan, Connie D. Brewster, James E. DiLisio, David F. Ackart, Brendan K. Podell, Randall J. Basaraba, Rushika Perera, Sandra L. Quackenbush, Joel Rovnak

Viruses. 2020 Jun; 12(6): 654. Published online 2020 Jun 17. doi: 10.3390/v12060654

PMCID:: PMC7354599

Abstract Article PDF–3.0M

Select item 72124817.

De Novo Variants in CDK19 Are Associated with a Syndrome Involving Intellectual Disability and Epileptic Encephalopathy

Hyung-lok Chung, Xiao Mao, Hua Wang, Ye-Jin Park, Paul C. Marcogliese, Jill A. Rosenfeld, Lindsay C. Burrage, Pengfei Liu, David R. Murdock, Shinya Yamamoto, Michael F. Wangler, Undiagnosed Diseases Network, Hsiao-Tuan Chao, Hongyu Long, Li Feng, Carlos A. Bacino, Hugo J. Bellen, Bo Xiao

Am J Hum Genet. 2020 May 7; 106(5): 717–725. Published online 2020 Apr 23. doi: 10.1016/j.ajhg.2020.04.001

PMCID:: PMC7212481

Abstract Article PDF–2.8M

Select item 66881158.

HIV Transcription Is Independent of Mediator Kinases

Daniele C. Cary, Mona Rheinberger, Ajda Rojc, B. Matija Peterlin

AIDS Res Hum Retroviruses. 2019 Aug 1; 35(8): 710–717. Published online 2019 Aug 1. doi: 10.1089/aid.2019.0039

PMCID:: PMC6688115

Abstract Article PDF–314K

Select item 66025679.

Regulatory functions of the Mediator kinases CDK8 and CDK19

Charli B. Fant, Dylan J. Taatjes

Transcription. 2019; 10(2): 76–90. Published online 2018 Dec 26. doi: 10.1080/21541264.2018.1556915

PMCID:: PMC6602567

Abstract Article PDF–1.5M

Select item 561729910.

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB

Mengqian Chen, Jiaxin Liang, Hao Ji, Zhengguan Yang, Serena Altilia, Bing Hu, Adam Schronce, Martina S. J. McDermott, Gary P. Schools, Chang-uk Lim, David Oliver, Michael S. Shtutman, Tao Lu, George R. Stark, Donald C. Porter, Eugenia V. Broude, Igor B. Roninson

Proc Natl Acad Sci U S A. 2017 Sep 19; 114(38): 10208–10213. Published online 2017 Aug 30. doi: 10.1073/pnas.1710467114

PMCID:: PMC5617299

Abstract Article PDF–1.1M

Select item 464152511.

Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML

Henry E. Pelish, Brian B. Liau, Ioana I. Nitulescu, Anupong Tangpeerachaikul, Zachary C. Poss, Diogo H. Da Silva, Brittany T. Caruso, Alexander Arefolov, Olugbeminiyi Fadeyi, Amanda L. Christie, Karrie Du, Deepti Banka, Elisabeth V. Schneider, Anja Jestel, Ge Zou, Chong Si, Christopher C. Ebmeier, Roderick T. Bronson, Andrei V. Krivtsov, Andrew G. Myers, Nancy E. Kohl, Andrew L. Kung, Scott A. Armstrong, Madeleine E. Lemieux, Dylan J. Taatjes, Matthew D. Shair

Nature. Author manuscript; available in PMC 2016 Apr 8.

Published in final edited form as: Nature. 2015 Oct 8; 526(7572): 273–276. Published online 2015 Sep 28. doi: 10.1038/nature14904

PMCID:: PMC4641525

Abstract Article PDF–2.6M

Select item 903370212.

Hotair promotes the migration and proliferation in ovarian cancer by miR-222-3p/CDK19 axis

Lili Fan, Han Lei, Ying Lin, Zhengwei Zhou, Juanni Li, Anqi Wu, Guang Shu, Sébastien Roger, Gang Yin

Cell Mol Life Sci. 2022 May; 79(5): 254. Published online 2022 Apr 22. doi: 10.1007/s00018-022-04250-0

PMCID:: PMC9033702

Abstract Article PDF–8.3M

Select item 956689013.

CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF

Marius V. Dannappel, Danxi Zhu, Xin Sun, Hui Kheng Chua, Marle Poppelaars, Monica Suehiro, Subash Khadka, Terry C.C. Lim Kam Sian, Dhanya Sooraj, Melissa Loi, Hugh Gao, Daniel Croagh, Roger J. Daly, Pouya Faridi, Thomas G. Boyer, Ron Firestein

J Clin Invest. 2022 Oct 17; 132(20): e158593. Published online 2022 Oct 17. doi: 10.1172/JCI158593

PMCID:: PMC9566890

Abstract Article PDF–9.1M

Select item 588013914.

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Min Ju Park, Hailian Shen, Jason M. Spaeth, Jaana H. Tolvanen, Courtney Failor, Jennifer F. Knudtson, Jessica McLaughlin, Sunil K. Halder, Qiwei Yang, Serdar E. Bulun, Ayman Al-Hendy, Robert S. Schenken, Lauri A. Aaltonen, Thomas G. Boyer

J Biol Chem. 2018 Mar 30; 293(13): 4870–4882. Published online 2018 Feb 13. doi: 10.1074/jbc.RA118.001725

PMCID:: PMC5880139

Abstract Article PDF–2.4M

Select item 377436515.

Mediator Complex Recruits Epigenetic Regulators via Its Two Cyclin-dependent Kinase Subunits to Repress Transcription of Immune Response Genes

Taiki Tsutsui, Rikiya Fukasawa, Kaori Shinmyouzu, Reiko Nakagawa, Kazuyuki Tobe, Aki Tanaka, Yoshiaki Ohkuma

J Biol Chem. 2013 Jul 19; 288(29): 20955–20965. Published online 2013 Jun 9. doi: 10.1074/jbc.M113.486746

PMCID:: PMC3774365

Abstract Article PDF–1.5M

Select item 637714816.

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7

Kerstin Köhler, Luis Sanchez-Pulido, Verena Höfer, Anika Marko, Chris P. Ponting, Ambrosius P. Snijders, Regina Feederle, Aloys Schepers, Dominik Boos

PLoS Biol. 2019 Jan; 17(1): e2006767. Published online 2019 Jan 29. doi: 10.1371/journal.pbio.2006767

PMCID:: PMC6377148

Abstract Article PDF–4.1M

Select item 291410417.

Cyclin-dependent kinases: a family portrait

Marcos Malumbres, Edward Harlow, Tim Hunt, Tony Hunter, Jill M. Lahti, Gerard Manning, David O. Morgan, Li-Huei Tsai, Debra J. Wolgemuth

Nat Cell Biol. Author manuscript; available in PMC 2010 Aug 2.

Published in final edited form as: Nat Cell Biol. 2009 Nov; 11(11): 1275–1276. doi: 10.1038/ncb1109-1275

PMCID:: PMC2914104

Article PDF–146K

Select item 364861218.

A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

Kuang-Lei Tsai, Shigeo Sato, Chieri Tomomori-Sato, Ronald C. Conaway, Joan W. Conaway, Francisco J. Asturias

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Nat Struct Mol Biol. 2013 May; 20(5): 611–619. Published online 2013 Apr 7. doi: 10.1038/nsmb.2549

PMCID:: PMC3648612

Abstract Article PDF–1.4M

Select item 282392219.

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

Anna Malovannaya, Yehua Li, Yaroslava Bulynko, Sung Yun Jung, Yi Wang, Rainer B. Lanz, Bert W. O’Malley, Jun Qin

Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2431–2436. Published online 2010 Jan 22. doi: 10.1073/pnas.0912599106

Correction in:: Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13): 6118.

PMCID:: PMC2823922

Abstract Article PDF–566K

Select item 314532520.

Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway

Cell. Author manuscript; available in PMC 2012 Jul 8.

Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005

PMCID:: PMC3145325

Abstract Article PDF–1.9M

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