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Select item 88653711.

LPIN1 Is a Regulatory Factor Associated With Immune Response and Inflammation in Sepsis

Wei Dai, Ping Zheng, Deqiang Luo, Qian Xie, Fen Liu, Qiang Shao, Ning Zhao, Kejian Qian

Front Immunol. 2022; 13: 820164. Published online 2022 Feb 9. doi: 10.3389/fimmu.2022.820164

PMCID:: PMC8865371

Abstract Article PDF–33M

Select item 83853272.

Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis

Yamina Hamel, François-Xavier Mauvais, Marine Madrange, Perrine Renard, Corinne Lebreton, Ivan Nemazanyy, Olivier Pellé, Nicolas Goudin, Xiaoyun Tang, Mathieu P. Rodero, Caroline Tuchmann-Durand, Patrick Nusbaum, David N. Brindley, Peter van Endert, Pascale de Lonlay

Cell Rep Med. 2021 Aug 17; 2(8): 100370. Published online 2021 Aug 17. doi: 10.1016/j.xcrm.2021.100370

PMCID:: PMC8385327

Abstract Article PDF–8.9M

Select item 78940203.

LPIN1 downregulation enhances anticancer activity of the novel HDAC/PI3K dual inhibitor FK‐A11

Hiroo Imai, Ken Saijo, Sonoko Chikamatsu, Yoshifumi Kawamura, Chikashi Ishioka

Cancer Sci. 2021 Feb; 112(2): 792–802. Published online 2021 Jan 8. doi: 10.1111/cas.14759

PMCID:: PMC7894020

Abstract Article PDF–1.4M

Select item 76007824.

Regulation of Signaling and Metabolism by Lipin-mediated Phosphatidic Acid Phosphohydrolase Activity

Andrew J. Lutkewitte, Brian N. Finck

Biomolecules. 2020 Oct; 10(10): 1386. Published online 2020 Sep 29. doi: 10.3390/biom10101386

PMCID:: PMC7600782

Abstract Article PDF–868K

Select item 72669915.

Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1

Jonghwa Lee, Jayme Salsman, Jason Foster, Graham Dellaire, Neale D Ridgway

Life Sci Alliance. 2020 Aug; 3(8): e202000751. Published online 2020 May 27. doi: 10.26508/lsa.202000751

PMCID:: PMC7266991

Abstract Article PDF–2.8M

Select item 70628816.

UVB-dependent inhibition of lipin-1 protects against proinflammatory responses in human keratinocytes

Minjung Chae, Eui Dong Son, Il-Hong Bae, Eun-Gyung Cho, Hyoung-June Kim, Ji-Yong Jung

Exp Mol Med. 2020 Feb; 52(2): 293–307. Published online 2020 Feb 21. doi: 10.1038/s12276-020-0388-y

PMCID:: PMC7062881

Abstract Article PDF–3.4M

Select item 61619007.

Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation

Lidia Mingorance, Victoria Castro, Ginés Ávila-Pérez, Gema Calvo, María Josefa Rodriguez, José L. Carrascosa, Sofía Pérez-del-Pulgar, Xavier Forns, Pablo Gastaminza

PLoS Pathog. 2018 Sep; 14(9): e1007284. Published online 2018 Sep 18. doi: 10.1371/journal.ppat.1007284

PMCID:: PMC6161900

Abstract Article PDF–7.4M

Select item 61375008.

Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival

Jingquan He, Feng Zhang, Li Wei Rachel Tay, Salome Boroda, Weiqi Nian, Kandice R. Levental, Ilya Levental, Thurl E. Harris, Jeffrey T. Chang, Guangwei Du

FASEB J. 2017 Jul; 31(7): 2893–2904. Published online 2017 Mar 27. doi: 10.1096/fj.201601353R

PMCID:: PMC6137500

Abstract Article

Select item 60108639.

Lipin‐1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy

Xueyu Fan, Yuanyuan Weng, Yongfeng Bai, Zongpan Wang, Siwei Wang, Jin Zhu, Feng Zhang

Cancer Med. 2018 Jun; 7(6): 2541–2554. Published online 2018 Apr 16. doi: 10.1002/cam4.1483

PMCID:: PMC6010863

Abstract Article PDF–1.0M

Select item 571149710.

Normal human adipose tissue functions and differentiation in patients with biallelic LPIN1 inactivating mutations

Michele Pelosi, Eric Testet, Soazig Le Lay, Isabelle Dugail, Xiaoyun Tang, Guillaume Mabilleau, Yamina Hamel, Marine Madrange, Thomas Blanc, Thierry Odent, Todd P. W. McMullen, Marco Alfò, David N. Brindley, Pascale de Lonlay

J Lipid Res. 2017 Dec; 58(12): 2348–2364. Published online 2017 Oct 6. doi: 10.1194/jlr.P075440

PMCID:: PMC5711497

Abstract Article PDF–1.5M

Select item 505026611.

LPIN1 deficiency: A novel mutation associated with different phenotypes in the same family

D Nunes, C Nogueira, A Lopes, P Chaves, E Rodrigues, T Cardoso, E Leão Teles, L Vilarinho

Mol Genet Metab Rep. 2016 Dec; 9: 29–30. Published online 2016 Oct 2. doi: 10.1016/j.ymgmr.2016.09.004

PMCID:: PMC5050266

Article PDF–336K

Select item 496934512.

Redundant roles of the phosphatidate phosphatase family in triacylglycerol synthesis in human adipocytes

Ana Temprano, Hiroshi Sembongi, Gil-Soo Han, David Sebastián, Jordi Capellades, Cristóbal Moreno, Juan Guardiola, Martin Wabitsch, Cristóbal Richart, Oscar Yanes, Antonio Zorzano, George M. Carman, Symeon Siniossoglou, Merce Miranda

Diabetologia. 2016; 59: 1985–1994. Published online 2016 Jun 25. doi: 10.1007/s00125-016-4018-0

PMCID:: PMC4969345

Abstract Article PDF–723K

Select item 480876513.

Lipin-1 expression is critical for keratinocyte differentiation

Minjung Chae, Ji-Yong Jung, Il-Hong Bae, Hyoung-June Kim, Tae Ryong Lee, Dong Wook Shin

J Lipid Res. 2016 Apr; 57(4): 563–573. doi: 10.1194/jlr.M062588

PMCID:: PMC4808765

Abstract Article PDF–1.3M

Select item 480875914.

Lipid signaling in keratinocytes: Lipin-1 plays a PArt

Wendy B. Bollag

J Lipid Res. 2016 Apr; 57(4): 523–525. doi: 10.1194/jlr.C067074

PMCID:: PMC4808759

Article PDF–506K

Select item 473321915.

Molecular analysis of LPIN1 in Jordanian patients with rhabdomyolysis

Saied A. Jaradat, Wajdi Amayreh, Kefah Al-Qa'qa', Jan Krayyem

Meta Gene. 2016 Feb; 7: 90–94. Published online 2015 Dec 22. doi: 10.1016/j.mgene.2015.12.003

PMCID:: PMC4733219

Abstract Article PDF–755K

Select item 448445516.

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment

Laura Brohée, Stéphane Demine, Jérome Willems, Thierry Arnould, Alain C. Colige, Christophe F. Deroanne

Oncotarget. 2015 May 10; 6(13): 11264–11280. Published online 2015 Mar 14. doi: 10.18632/oncotarget.3595

PMCID:: PMC4484455

Abstract Article PDF–3.0M

Select item 400709917.

Combination of lipid metabolism alterations and their sensitivity to inflammatory cytokines in human lipin-1-deficient myoblasts

Caroline Michot, Asmaa Mamoune, Joseph Vamecq, Mai Thao Viou, Lu-Sheng Hsieh, Eric Testet, Jeanne Lainé, Laurence Hubert, Anne-Frédérique Dessein, Monique Fontaine, Chris Ottolenghi, Laetitia Fouillen, Karim Nadra, Etienne Blanc, Jean Bastin, Sophie Candon, Mario Pende, Arnold Munnich, Asma Smahi, Fatima Djouadi, George M. Carman, Norma Romero, Yves de Keyzer, Pascale de Lonlay

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Dec; 1832(12): 2103–2114. Published online 2013 Aug 6. doi: 10.1016/j.bbadis.2013.07.021

PMCID:: PMC4007099

Abstract Article PDF–1.2M

Select item 383093718.

Lipins, Lipinopathies, and the Modulation of Cellular Lipid Storage and Signaling

Lauren S. Csaki, Jennifer R. Dwyer, Loren G. Fong, Peter Tontonoz, Stephen G. Young, Karen Reue

Prog Lipid Res. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Prog Lipid Res. 2013 Jul; 52(3): 10.1016/j.plipres.2013.04.001. Published online 2013 Apr 17. doi: 10.1016/j.plipres.2013.04.001

PMCID:: PMC3830937

Abstract Article PDF–398K

Select item 351638219.

Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression

Ilias Mylonis, Hiroshi Sembongi, Christina Befani, Panagiotis Liakos, Symeon Siniossoglou, George Simos

J Cell Sci. 2012 Jul 15; 125(14): 3485–3493. doi: 10.1242/jcs.106682

PMCID:: PMC3516382

Abstract Article

Select item 311727220.

Lipin-1 gamma isoform is a novel lipid droplet-associated protein highly expressed in the brain

Huajin Wang, Jing Zhang, Wei Qiu, Gil-Soo Han, George M. Carman, Khosrow Adeli

FEBS Lett. Author manuscript; available in PMC 2012 Jun 23.

Published in final edited form as: FEBS Lett. 2011 Jun 23; 585(12): 1979–1984. Published online 2011 May 20. doi: 10.1016/j.febslet.2011.05.035

PMCID:: PMC3117272

Abstract Article PDF–1.6M

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