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Items: 1 to 20 of 26

1.
Prevalence and clinical characteristics of T2DM patients with OTUD3 gene rs78466831 SNP at a single academic center in China
Jian-Ping Liu, Ai-Ping Yang, Gang Lei, Man Yu, Yu Peng, Ai-ping Le
Front Endocrinol (Lausanne) 2022; 13: 1059641. Published online 2022 Dec 2. doi: 10.3389/fendo.2022.1059641
PMCID:
PMC9755877
AbstractArticlePDF–1.7M
2.
The deubiquitinase OTUD3 stabilizes ACTN4 to drive growth and metastasis of hepatocellular carcinoma
Peiyi Xie, Yanglin Chen, Hongfei Zhang, Guichao Zhou, Qing Chao, Jiangwen Wang, Yue Liu, Jiayu Fang, Jing Xie, Jing Zhen, Zhiyuan Wang, Liang Hao, Da Huang
Aging (Albany NY) 2021 Aug 15; 13(15): 19317–19338. Published online 2021 Aug 10. doi: 10.18632/aging.203293
PMCID:
PMC8386523
AbstractArticlePDF–3.0M
3.
Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells
Qian Pu, Yan-rong Lv, Ke Dong, Wen-wen Geng, Hai-dong Gao
BMC Cancer. 2020; 20: 583. Published online 2020 Jun 22. doi: 10.1186/s12885-020-07069-9
PMCID:
PMC7310228
AbstractArticlePDF–2.0M
4.
Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized
Danielle M Garshott, Elayanambi Sundaramoorthy, Marilyn Leonard, Eric J Bennett
eLife. 2020; 9: e54023. Published online 2020 Feb 3. doi: 10.7554/eLife.54023
PMCID:
PMC7064338
AbstractArticlePDF–4.5M
5.
miR-520h Stimulates Drug Resistance to Paclitaxel by Targeting the OTUD3-PTEN Axis in Breast Cancer
Wenwen Geng, Haiyun Song, Qianqian Zhao, Ke Dong, Qian Pu, Haidong Gao, Yanrong Lv
Biomed Res Int. 2020; 2020: 9512793. Published online 2020 May 9. doi: 10.1155/2020/9512793
PMCID:
PMC7391095
AbstractArticlePDF–1.8M
6.
Deubiquitylase OTUD3 Mediates Endoplasmic Reticulum Stress through Regulating Fortilin Stability to Restrain Dopaminergic Neurons Apoptosis
Ling Chen, Xuejie Huan, Fengju Jia, Zhen Zhang, Mingxia Bi, Lin Fu, Xixun Du, Xi Chen, Chunling Yan, Qian Jiao, Hong Jiang
Antioxidants (Basel) 2023 Apr; 12(4): 809. Published online 2023 Mar 26. doi: 10.3390/antiox12040809
PMCID:
PMC10135230
AbstractArticlePDF–3.4M
7.
Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2
Fengju Jia, Hongchang Li, Qian Jiao, Chaonan Li, Lin Fu, Chunping Cui, Hong Jiang, Lingqiang Zhang
Cell Death Dis. 2022 Apr; 13(4): 418. Published online 2022 Apr 30. doi: 10.1038/s41419-022-04704-0
PMCID:
PMC9056525
AbstractArticlePDF–6.3M
8.
Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer
Meng Wang, Yue Li, Yunyun Xiao, Muwen Yang, Jinxin Chen, Yunting Jian, Xin Chen, Dongni Shi, Xiangfu Chen, Ying Ouyang, Lingzhi Kong, Xinjian Huang, Jiewen Bai, Chuyong Lin, Libing Song
Nat Commun. 2021; 12: 7006. Published online 2021 Dec 1. doi: 10.1038/s41467-021-27348-8
PMCID:
PMC8636640
AbstractArticlePDF–7.4M
9.
Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer
Pengfei Zhang, Chaonan Li, Hongchang Li, Lin Yuan, Hongmiao Dai, Zhiqiang Peng, Zhikang Deng, Zhijie Chang, Chun-Ping Cui, Lingqiang Zhang
Cell Death Differ. 2020 Nov; 27(11): 3177–3195. Published online 2020 Jun 1. doi: 10.1038/s41418-020-0571-7
PMCID:
PMC7560627
AbstractArticlePDF–6.1M
10.
Assembly, analysis and architecture of atypical ubiquitin chains
Manuela K. Hospenthal, Stefan M.V. Freund, David Komander
Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Sep 27.
Published in final edited form as: Nat Struct Mol Biol. 2013 May; 20(5): 555–565. Published online 2013 Apr 7. doi: 10.1038/nsmb.2547
PMCID:
PMC4176834
AbstractArticlePDF–3.4M
11.
SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth
Siyuan Su, Jianfeng Chen, Yao Jiang, Ying Wang, Tamara Vital, Jiaming Zhang, Christian Laggner, Kong T. Nguyen, Zhichuan Zhu, Alex W. Prevatte, Natalie K. Barker, Laura E. Herring, Ian J. Davis, Pengda Liu
Adv Sci (Weinh) 2021 Jul; 8(14): 2004846. Published online 2021 Jun 1. doi: 10.1002/advs.202004846
PMCID:
PMC8292909
AbstractArticlePDF–4.0M
12.
Identification and validation of Selective Deubiquitinase Inhibitors
Anthony C. Varca, Dominick Casalena, Wai Cheung Chan, Bin Hu, Robert S. Magin, Rebekka M. Roberts, Xiaoxi Liu, He Zhu, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jarrod A. Marto, Douglas Auld, Sara J. Buhrlage
Cell Chem Biol. Author manuscript; available in PMC 2022 Dec 16.
Published in final edited form as: Cell Chem Biol. 2021 Dec 16; 28(12): 1758–1771.e13. Published online 2021 Jun 14. doi: 10.1016/j.chembiol.2021.05.012
PMCID:
PMC9473745
AbstractArticlePDF–2.3M
13.
Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets
Dennis Flierman, Gerbrand J. van der Heden van Noort, Reggy Ekkebus, Paul P. Geurink, Tycho E.T. Mevissen, Manuela K. Hospenthal, David Komander, Huib Ovaa
Cell Chem Biol. 2016 Apr 21; 23(4): 472–482. Published online 2016 Apr 21. doi: 10.1016/j.chembiol.2016.03.009
PMCID:
PMC4850247
AbstractArticle
14.
The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis
Tongde Du, Hongchang Li, Yongsheng Fan, Lin Yuan, Xiaodan Guo, Qiong Zhu, Yuying Yao, Xin Li, Chunlei Liu, Xinhe Yu, Zhaofei Liu, Chun-Ping Cui, Chuanchun Han, Lingqiang Zhang
Nat Commun. 2019; 10: 2914. Published online 2019 Jul 2. doi: 10.1038/s41467-019-10824-7
PMCID:
PMC6606649
AbstractArticlePDF–4.7M
15.
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
The UK IBD Genetics Consortium, The Wellcome Trust Case Control Consortium 2
Nat Genet. Author manuscript; available in PMC 2010 Jun 1.
Published in final edited form as: Nat Genet. 2009 Dec; 41(12): 1330–1334. Published online 2009 Nov 15. doi: 10.1038/ng.483
PMCID:
PMC2812019
AbstractArticlePDF–597K
16.
Ulcerative colitis loci on chromosomes 1p36 and 12q15 identified by genome-wide association study
Mark S. Silverberg, Judy H. Cho, John D. Rioux, Dermot P.B. McGovern, Jing Wu, Vito Annese, Jean-Paul Achkar, Philippe Goyette, Regan Scott, Wei Xu, M. Michael Barmada, Lambertus Klei, Mark J. Daly, Clara Abraham, Theodore M. Bayless, Fabrizio Bossa, Anne M. Griffiths, Andrew F. Ippoliti, Raymond G. Lahaie, Anna Latiano, Pierre Paré, Deborah D. Proctor, Miguel D. Regueiro, A. Hillary Steinhart, Stephan R. Targan, L. Philip Schumm, Emily O. Kistner, Annette T. Lee, Peter K. Gregersen, Jerome I. Rotter, Steven R. Brant, Kent D. Taylor, Kathryn Roeder, Richard H. Duerr
Nat Genet. Author manuscript; available in PMC 2009 Aug 1.
Published in final edited form as: Nat Genet. 2009 Feb; 41(2): 216–220. Published online 2009 Jan 4. doi: 10.1038/ng.275
Correction in:
volume 41 on page 762
PMCID:
PMC2652837
AbstractArticlePDF–571K
17.
KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1
Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng
Theranostics. 2021; 11(13): 6278–6292. Published online 2021 Apr 15. doi: 10.7150/thno.57455
PMCID:
PMC8120227
AbstractArticlePDF–2.7M
18.
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Dermot P.B. McGovern, Agnès Gardet, Leif Törkvist, Philippe Goyette, Jonah Essers, Kent D. Taylor, Benjamin M. Neale, Rick T.H. Ong, Caroline Lagacé, Chun Li, Todd Green, Christine R. Stevens, Claudine Beauchamp, Phillip R. Fleshner, Marie Carlson, Mauro D'Amato, Jonas Halfvarson, Martin L. Hibberd, Mikael Lördal, Leonid Padyukov, Angelo Andriulli, Elisabetta Colombo, Anna Latiano, Orazio Palmieri, Edmond-Jean Bernard, Colette Deslandres, Daan W. Hommes, Dirk J de Jong, Pieter C. Stokkers, Rinse K. Weersma, The NIDDK IBDGC, Yashoda Sharma, Mark Silverberg, Judy H. Cho, Jing Wu, Kathryn Roeder, Steven R. Brant, L. Phillip Schumm, Richard H. Duerr, Marla C. Dubinsky, Nicole L. Glazer, Talin Haritunians, Andy Ippoliti, Gil Y. Melmed, David S. Siscovick, Eric A. Vasiliauskas, Stephan R. Targan, Vito Annese, Cisca Wijmenga, Sven Pettersson, Jerome I. Rotter, Ramnik J. Xavier, Mark J. Daly, John D. Rioux, Mark Seielstad
Nat Genet. Author manuscript; available in PMC 2011 May 4.
Published in final edited form as: Nat Genet. 2010 Apr; 42(4): 332–337. Published online 2010 Mar 14. doi: 10.1038/ng.549
Correction in:
volume 43 on page 388
PMCID:
PMC3087600
AbstractArticlePDF–505K
19.
OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase
Hyo Jin Kim, Jongchan Kim
Int J Mol Sci. 2021 Feb; 22(4): 1936. Published online 2021 Feb 16. doi: 10.3390/ijms22041936
PMCID:
PMC7919836
AbstractArticlePDF–5.0M
20.
OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink, Paul R. Elliott, Masato Akutsu, Nadia Arnaudo, Reggy Ekkebus, Yogesh Kulathu, Tobias Wauer, Farid El Oualid, Stefan M.V. Freund, Huib Ovaa, David Komander
Cell. 2013 Jul 3; 154(1): 169–184. doi: 10.1016/j.cell.2013.05.046
PMCID:
PMC3705208
AbstractArticle

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