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Select item 102566391.

Estimation of FMO3 Ontogeny by Mechanistic Population Pharmacokinetic Modelling of Risdiplam and Its Impact on Drug–Drug Interactions in Children

Yumi Cleary, Heidemarie Kletzl, Paul Grimsey, Katja Heinig, Kayode Ogungbenro, Hanna Elisabeth Silber Baumann, Nicolas Frey, Leon Aarons, Aleksandra Galetin, Michael Gertz

Clin Pharmacokinet. 2023; 62(6): 891–904. Published online 2023 May 6. doi: 10.1007/s40262-023-01241-7

PMCID:: PMC10256639

Abstract Article PDF–2.1M

Select item 86187682.

Adaptive Modelling of Mutated FMO3 Enzyme Could Unveil Unexplored Scenarios Linking Variant Haplotypes to TMAU Phenotypes

Simona Alibrandi, Fabiana Nicita, Luigi Donato, Concetta Scimone, Carmela Rinaldi, Rosalia D’Angelo, Antonina Sidoti

Molecules. 2021 Nov; 26(22): 7045. Published online 2021 Nov 22. doi: 10.3390/molecules26227045

PMCID:: PMC8618768

Abstract Article PDF–3.6M

Select item 56971033.

Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver

Meijuan Xu, Deepak Kumar Bhatt, Catherine K. Yeung, Katrina G. Claw, Amarjit S. Chaudhry, Andrea Gaedigk, Robin E. Pearce, Ulrich Broeckel, Roger Gaedigk, Deborah A. Nickerson, Erin Schuetz, Allan E. Rettie, J. Steven Leeder, Kenneth E. Thummel, Bhagwat Prasad

J Pharmacol Exp Ther. 2017 Nov; 363(2): 265–274. Published online 2017 Nov. doi: 10.1124/jpet.117.243113

PMCID:: PMC5697103

Abstract Article PDF–714K

Select item 56796294.

Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway

Ibrahim El-Serafi, Ylva Terelius, Manuchehr Abedi-Valugerdi, Seán Naughton, Maryam Saghafian, Ali Moshfegh, Jonas Mattsson, Zuzana Potácová, Moustapha Hassan

PLoS One. 2017; 12(11): e0187294. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0187294

Correction in:: PLoS One. 2017; 12(12): e0190181.

PMCID:: PMC5679629

Abstract Article PDF–3.3M

Select item 53463825.

Effects of FMO3 Polymorphisms on Pharmacokinetics of Sulindac in Chinese Healthy Male Volunteers

Yong-Jun Tang, Kai Hu, Wei-Hua Huang, Chong-Zhi Wang, Zhi Liu, Yao Chen, Dong-Sheng Ouyang, Zhi-Rong Tan, Hong-Hao Zhou, Chun-Su Yuan

Biomed Res Int. 2017; 2017: 4189678. Published online 2017 Feb 26. doi: 10.1155/2017/4189678

PMCID:: PMC5346382

Abstract Article PDF–1.0M

Select item 49813776.

Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients

Cassianne Robinson-Cohen, Richard Newitt, Danny D. Shen, Allan E. Rettie, Bryan R. Kestenbaum, Jonathan Himmelfarb, Catherine K. Yeung

PLoS One. 2016; 11(8): e0161074. Published online 2016 Aug 11. doi: 10.1371/journal.pone.0161074

PMCID:: PMC4981377

Abstract Article PDF–496K

Select item 47557197.

Inter-individual variations of flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors

Satomi Nagashima, Makiko Shimizu, Hiroshi Yano, Norie Murayama, Toshio Kumai, Shinichi Kobayashi, F. Peter Guengerich, Hiroshi Yamazaki

Drug Metab Pharmacokinet. Author manuscript; available in PMC 2016 Feb 16.

Published in final edited form as: Drug Metab Pharmacokinet. 2009; 24(3): 218–225. doi: 10.2133/dmpk.24.218

PMCID:: PMC4755719

Abstract Article PDF–910K

Select item 46665148.

Emerging Roles of Flavin Monooxygenase 3 (FMO3) in Cholesterol Metabolism and Atherosclerosis

Rebecca C. Schugar, J. Mark Brown

Curr Opin Lipidol. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Curr Opin Lipidol. 2015 Oct; 26(5): 426–431. doi: 10.1097/MOL.0000000000000215

PMCID:: PMC4666514

Abstract Article PDF–263K

Select item 45830639.

Effects upon in vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption

Dr. A. Joseph Bloom, Dr. Sharon E. Murphy, Ms. Maribel Martinez, Dr. Linda B. von Weymarn, Dr. Laura J. Bierut, Dr. Alison Goate

Pharmacogenet Genomics. Author manuscript; available in PMC 2015 Sep 25.

Published in final edited form as: Pharmacogenet Genomics. 2013 Feb; 23(2): 62–68. doi: 10.1097/FPC.0b013e32835c3b48

PMCID:: PMC4583063

Abstract Article PDF–292K

Select item 440195110.

Fish Malodour syndrome in a child

Alexandra Oliveira, Ana Faria, Mónica Oliva

BMJ Case Rep. 2015; 2015: bcr2014207002. Published online 2015 Apr 13. doi: 10.1136/bcr-2014-207002

PMCID:: PMC4401951

Abstract Article PDF–233K

Select item 419059211.

Fish odor syndrome (trimethylaminuria) supporting the possible FMO3 down expression in childhood: a case report

Rosalia D’Angelo, Concetta Scimone, Teresa Esposito, Daniele Bruschetta, Carmela Rinaldi, Alessia Ruggeri, Antonina Sidoti

J Med Case Rep. 2014; 8: 328. Published online 2014 Oct 6. doi: 10.1186/1752-1947-8-328

PMCID:: PMC4190592

Abstract Article PDF–254K

Select item 400440412.

Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population

Makiko Shimizu, Charles K Allerston, Elizabeth A Shephard, Hiroshi Yamazaki, Ian R Phillips

Br J Clin Pharmacol. 2014 May; 77(5): 839–851. Published online 2014 Apr 22. doi: 10.1111/bcp.12240

PMCID:: PMC4004404

Abstract Article PDF–1.1M

Select item 364702213.

Inflammation in the Setting of Chronic Allograft Dysfunction Post-Kidney Transplant: Phenotype & Genotype

Ajay K. Israni, Robert Leduc, Pamala A. Jacobson, Winston Wildebush, Weihua Guan, David Schladt, Arthur J. Matas, William S. Oetting

Clin Transplant. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Clin Transplant. 2013 May; 27(3): 348–358. Published online 2013 Jan 27. doi: 10.1111/ctr.12074

PMCID:: PMC3647022

Abstract Article PDF–599K

Select item 273959314.

Novel Variants of the Human Flavin-Containing Monooxygenase 3 (FMO3) Gene Associated with Trimethylaminuria

Meike S. Motika, Jun Zhang, Xueying Zheng, Kiersten Riedler, John R. Cashman

Mol Genet Metab. Author manuscript; available in PMC 2010 Jun 1.

Published in final edited form as: Mol Genet Metab. 2009 Jun; 97(2): 128–135. Published online 2009 Feb 27. doi: 10.1016/j.ymgme.2009.02.006

PMCID:: PMC2739593

Abstract Article PDF–321K

Select item 237333615.

Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase

Andrea Alfieri, Enrico Malito, Roberto Orru, Marco W. Fraaije, Andrea Mattevi

Proc Natl Acad Sci U S A. 2008 May 6; 105(18): 6572–6577. Published online 2008 Apr 28. doi: 10.1073/pnas.0800859105

PMCID:: PMC2373336

Abstract Article PDF–1.2M

Select item 221390716.

Genetic polymorphisms of human flavin-containing monooxygenase 3: implications for drug metabolism and clinical perspectives

Irfan M Hisamuddin, Vincent W Yang

Pharmacogenomics. Author manuscript; available in PMC 2008 Jan 25.

Published in final edited form as: Pharmacogenomics. 2007 Jun; 8(6): 635–643. doi: 10.2217/14622416.8.6.635

PMCID:: PMC2213907

Abstract Article PDF–557K

Select item 221362617.

Genetic Polymorphisms of Flavin Monooxygenase 3 in Sulindac-Induced Regression of Colorectal Adenomas in Familial Adenomatous Polyposis

Irfan M. Hisamuddin, Mohammad A. Wehbi, Brian Schmotzer, Kirk A. Easley, Linda M. Hylind, Francis M. Giardiello, Vincent W. Yang

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2008 Jan 24.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2005 Oct; 14(10): 2366–2369. doi: 10.1158/1055-9965.EPI-05-0312

PMCID:: PMC2213626

Abstract Article PDF–126K

Select item 203992118.

Functional Characterization of Genetic Variants of Human FMO3 Associated with Trimethylaminuria

Catherine K. Yeung, Elinor T. Adman, Allan E. Rettie

Arch Biochem Biophys. Author manuscript; available in PMC 2008 Aug 15.

Published in final edited form as: Arch Biochem Biophys. 2007 Aug 15; 464(2): 251–259. Published online 2007 May 2. doi: 10.1016/j.abb.2007.04.014

PMCID:: PMC2039921

Abstract Article PDF–927K

Select item 179088519.

Transient trimethylaminuria related to menstruation

Makiko Shimizu, John R Cashman, Hiroshi Yamazaki

BMC Med Genet. 2007; 8: 2. Published online 2007 Jan 27. doi: 10.1186/1471-2350-8-2

PMCID:: PMC1790885

Abstract Article PDF–267K

Select item 4091220.

Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.

N Lomri, Q Gu, J R Cashman

Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21): 9910. doi: 10.1073/pnas.92.21.9910

Corrects:: Proc Natl Acad Sci U S A. 1992 Mar 1; 89(5): 1685–1689.

PMCID:: PMC40912

Correction PDF–163K

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PMC Links for Gene (Select 2328) (46)
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Slfn2 schlafen family member 2 [Rattus norvegicus]
Slfn2 schlafen family member 2 [Rattus norvegicus]
Gene ID:303380

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Zfp207 zinc finger protein 207 [Rattus norvegicus]
Zfp207 zinc finger protein 207 [Rattus norvegicus]
Gene ID:303763

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