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Items: 1 to 20 of 51

1.
Critical role of SIK3 in mediating high salt and IL-17 synergy leading to breast cancer cell proliferation
Suneetha Amara, Ciera Majors, Bipradas Roy, Salisha Hill, Kristie L. Rose, Elbert L. Myles, Venkataswarup Tiriveedhi
PLoS One. 2017; 12(6): e0180097. Published online 2017 Jun 28. doi: 10.1371/journal.pone.0180097
PMCID:
PMC5489190
AbstractArticlePDF–3.2M
2.
Faecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer
C-J Huang, C-C Chien, S-H Yang, C-C Chang, H-L Sun, Y-C Cheng, C-C Liu, S-C Lin, C-M Lin
J Cell Mol Med. 2008 Oct; 12(5b): 1936–1943. Published online 2008 Feb 6. doi: 10.1111/j.1582-4934.2008.00253.x
PMCID:
PMC4506161
AbstractArticlePDF–322K
3.
Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses
Luke D. Hutchinson, Nicola J. Darling, Stephanos Nicolaou, Ilaria Gori, Daniel R. Squair, Philip Cohen, Caroline S. Hill, Gopal P. Sapkota
Cell Death Dis. 2020 Jan; 11(1): 49. Published online 2020 Jan 22. doi: 10.1038/s41419-020-2241-6
PMCID:
PMC6976658
AbstractArticlePDF–2.7M
4.
Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes
Johanna Säll, Annie M. L. Pettersson, Christel Björk, Emma Henriksson, Sebastian Wasserstrom, Wilhelm Linder, Yuedan Zhou, Ola Hansson, Daniel P. Andersson, Mikael Ekelund, Eva Degerman, Karin G. Stenkula, Jurga Laurencikiene, Olga Göransson
Diabetologia. 2017; 60(2): 314–323. Published online 2016 Nov 2. doi: 10.1007/s00125-016-4141-y
PMCID:
PMC6518086
AbstractArticlePDF–631K
5.
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3
Yasuhito Yahara, Hiroshi Takemori, Minoru Okada, Azuma Kosai, Akihiro Yamashita, Tomohito Kobayashi, Kaori Fujita, Yumi Itoh, Masahiro Nakamura, Hiroyuki Fuchino, Nobuo Kawahara, Naoshi Fukui, Akira Watanabe, Tomoatsu Kimura, Noriyuki Tsumaki
Nat Commun. 2016; 7: 10959. Published online 2016 Mar 24. doi: 10.1038/ncomms10959
Correction in:
Nat Commun. 2016; 7: 12117.
PMCID:
PMC4820810
AbstractArticlePDF–3.0M
6.
Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death
H Chen, S Huang, X Han, J Zhang, C Shan, Y H Tsang, H T Ma, R Y C Poon
Cell Death Dis. 2014 Apr; 5(4): e1177. Published online 2014 Apr 17. doi: 10.1038/cddis.2014.154
PMCID:
PMC4001308
AbstractArticlePDF–2.5M
7.
An Lkb1-Sik axis suppresses lung tumor growth and controls differentiation
Christopher W. Murray, Jennifer J. Brady, Min K. Tsai, Chuan Li, Ian P. Winters, Rui Tang, Laura Andrejka, Rosanna K. Ma, Christian A. Kunder, Pauline Chu, Monte M. Winslow
Cancer Discov. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Cancer Discov. 2019 Nov; 9(11): 1590–1605. Published online 2019 Jul 26. doi: 10.1158/2159-8290.CD-18-1237
PMCID:
PMC6825558
AbstractArticlePDF–3.2M
8.
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia
Yusuke Tarumoto, Bin Lu, Tim D. D. Somerville, Yu-Han Huang, Joseph P. Milazzo, Xiaoli S. Wu, Olaf Klingbeil, Osama El Demerdash, Junwei Shi, Christopher R. Vakoc
Mol Cell. Author manuscript; available in PMC 2019 Mar 15.
Published in final edited form as: Mol Cell. 2018 Mar 15; 69(6): 1017–1027.e6. Published online 2018 Mar 8. doi: 10.1016/j.molcel.2018.02.011
PMCID:
PMC5856641
AbstractArticlePDF–1.9M
9.
Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis
Fusheng Zhou, Changbing Shen, Jingkai Xu, Jing Gao, Xiaodong Zheng, Randy Ko, Jinfa Dou, Yuyan Cheng, Caihong Zhu, Shuangjun Xu, Xianfa Tang, Xianbo Zuo, Xianyong Yin, Yong Cui, Liangdan Sun, Lam C. Tsoi, Yi-Hsiang Hsu, Sen Yang, Xuejun Zhang
Clin Epigenetics. 2016; 8: 131. Published online 2016 Dec 5. doi: 10.1186/s13148-016-0297-z
PMCID:
PMC5139011
AbstractArticlePDF–1.4M
10.
Salt-inducible Kinases Are Critical Determinants of Female Fertility
Marah Armouti, Nicola Winston, Osamu Hatano, Elie Hobeika, Jennifer Hirshfeld-Cytron, Juergen Liebermann, Hiroshi Takemori, Carlos Stocco
Endocrinology. 2020 Jul; 161(7): bqaa069. Published online 2020 Apr 28. doi: 10.1210/endocr/bqaa069
PMCID:
PMC7286620
AbstractArticle
11.
PTH/PTHrP-SIK3 mediated pathway affects skeletogenesis through altered mTOR signaling
Fabiana Csukasi, Ivan Duran, Maya Barad, Tomas Barta, Iva Gudernova, Lukas Trantirek, Jorge Martin, Caroline Y. Kuo, Jeremy Woods, Hane Lee, Daniel H. Cohn, Pavel Krejci, Deborah Krakow
Sci Transl Med. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Sci Transl Med. 2018 Sep 19; 10(459): eaat9356. doi: 10.1126/scitranslmed.aat9356
PMCID:
PMC7529349
AbstractArticlePDF–1.8M
12.
14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs)
Tim Sonntag, Joan M. Vaughan, Marc Montminy
FEBS J. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: FEBS J. 2018 Feb; 285(3): 467–480. Published online 2018 Jan 9. doi: 10.1111/febs.14351
PMCID:
PMC5799007
AbstractArticlePDF–2.3M
13.
Common Variants near MBNL1 and NKX2-5 are Associated with Infantile Hypertrophic Pyloric Stenosis
Bjarke Feenstra, Frank Geller, Camilla Krogh, Mads V. Hollegaard, Sanne Gørtz, Heather A. Boyd, Jeffrey C. Murray, David M. Hougaard, Mads Melbye
Nat Genet. Author manuscript; available in PMC 2013 Jun 26.
Published in final edited form as: Nat Genet. 2012 Feb 5; 44(3): 334–337. Published online 2012 Feb 5. doi: 10.1038/ng.1067
PMCID:
PMC3693399
ArticlePDF–785K
14.
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels
Konrad Oexle, Janina S. Ried, Andrew A. Hicks, Toshiko Tanaka, Caroline Hayward, Mathias Bruegel, Martin Gögele, Peter Lichtner, Bertram Müller-Myhsok, Angela Döring, Thomas Illig, Christine Schwienbacher, Cosetta Minelli, Irene Pichler, G. Martin Fiedler, Joachim Thiery, Igor Rudan, Alan F. Wright, Harry Campbell, Luigi Ferrucci, Stefania Bandinelli, Peter P. Pramstaller, H.-Erich Wichmann, Christian Gieger, Juliane Winkelmann, Thomas Meitinger
Hum Mol Genet. 2011 Mar 1; 20(5): 1042–1047. Published online 2010 Dec 10. doi: 10.1093/hmg/ddq538
PMCID:
PMC3033185
AbstractArticlePDF–187K
15.
Salt-Inducible Kinases 1 and 3 Negatively Regulate Toll-Like Receptor 4-Mediated Signal
So Yong Kim, Sookyung Jeong, Kyong-Hwa Chah, Eunyu Jung, Kwan-Hyuck Baek, Seong-Tae Kim, Jae-Hyuck Shim, Eunyoung Chun, Ki-Young Lee
Mol Endocrinol. 2013 Nov; 27(11): 1958–1968. Published online 2013 Sep 23. doi: 10.1210/me.2013-1240
PMCID:
PMC5427829
AbstractArticle
16.
The Tumor Suppressor Kinase LKB1 Activates the Downstream Kinases SIK2 and SIK3 to Stimulate Nuclear Export of Class IIa Histone Deacetylases
Donald R. Walkinshaw, Ryan Weist, Go-Woon Kim, Linya You, Lin Xiao, Jianyun Nie, Cathy S. Li, Songping Zhao, Minghong Xu, Xiang-Jiao Yang
J Biol Chem. 2013 Mar 29; 288(13): 9345–9362. Published online 2013 Feb 7. doi: 10.1074/jbc.M113.456996
PMCID:
PMC3611005
AbstractArticlePDF–2.8M
17.
Salt-inducible kinase 3, SIK3, is a new gene associated with hearing
Lisa E. Wolber, Giorgia Girotto, Annalisa Buniello, Dragana Vuckovic, Nicola Pirastu, Beatriz Lorente-Cánovas, Igor Rudan, Caroline Hayward, Ozren Polasek, Marina Ciullo, Massimo Mangino, Claire Steves, Maria Pina Concas, Massilimiliano Cocca, Tim D. Spector, Paolo Gasparini, Karen P. Steel, Frances M.K. Williams
Hum Mol Genet. 2014 Dec 1; 23(23): 6407–6418. Published online 2014 Jul 24. doi: 10.1093/hmg/ddu346
PMCID:
PMC4222365
AbstractArticlePDF–907K
18.
Genome-Wide Association Study Identifies Three Common Variants Associated with Serologic Response to Vitamin E Supplementation in Men
Jacqueline M. Major, Kai Yu, Charles C. Chung, Stephanie J. Weinstein, Meredith Yeager, William Wheeler, Kirk Snyder, Margaret E. Wright, Jarmo Virtamo, Stephen Chanock, Demetrius Albanes
J Nutr. 2012 May; 142(5): 866–871. Published online 2012 Mar 21. doi: 10.3945/jn.111.156349
PMCID:
PMC3327745
AbstractArticlePDF–855K
19.
Amerindian-specific regions under positive selection harbour new lipid variants in Latinos
Arthur Ko, Rita M. Cantor, Daphna Weissglas-Volkov, Elina Nikkola, Prasad M. V. Linga Reddy, Janet S. Sinsheimer, Bogdan Pasaniuc, Robert Brown, Marcus Alvarez, Alejandra Rodriguez, Rosario Rodriguez-Guillen, Ivette C. Bautista, Olimpia Arellano-Campos, Linda L. Muñoz-Hernández, Veikko Salomaa, Jaakko Kaprio, Antti Jula, Matti Jauhiainen, Markku Heliövaara, Olli Raitakari, Terho Lehtimäki, Johan G. Eriksson, Markus Perola, Kirk E. Lohmueller, Niina Matikainen, Marja-Riitta Taskinen, Maribel Rodriguez-Torres, Laura Riba, Teresa Tusie-Luna, Carlos A. Aguilar-Salinas, Päivi Pajukanta
Nat Commun. 2014 Jun 2; 5: 3983. Published online 2014 Jun 2. doi: 10.1038/ncomms4983
PMCID:
PMC4062071
AbstractArticlePDF–821K
20.
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
Jose M Lizcano, Olga Göransson, Rachel Toth, Maria Deak, Nick A Morrice, Jérôme Boudeau, Simon A Hawley, Lina Udd, Tomi P Mäkelä, D Grahame Hardie, Dario R Alessi
EMBO J. 2004 Feb 25; 23(4): 833–843. Published online 2004 Feb 19. doi: 10.1038/sj.emboj.7600110
PMCID:
PMC381014
AbstractArticlePDF–586K

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