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Items: 1 to 20 of 200

1.
Conformational diversity of human HP1α
Tina Ukmar‐Godec, Taekyung Yu, Alain Ibanez de Opakua, Christian F. Pantoja, Francesca Munari, Markus Zweckstetter
Protein Sci. 2024 Jul; 33(7): e5079. Published online 2024 Jun 19. doi: 10.1002/pro.5079
PMCID:
PMC11187854
AbstractArticlePDF–6.9M
2.
Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres
Kosuke Sako, Ayako Furukawa, Ryu-Suke Nozawa, Jun-ichi Kurita, Yoshifumi Nishimura, Toru Hirota
J Cell Biol. 2024 Sep 2; 223(9): e202312021. Published online 2024 May 23. doi: 10.1083/jcb.202312021
PMCID:
PMC11116813
AbstractArticlePDF–7.4M
3.
Molecular interactions underlying the phase separation of HP1α: role of phosphorylation, ligand and nucleic acid binding
Cheenou Her, Tien M Phan, Nina Jovic, Utkarsh Kapoor, Bryce E Ackermann, Azamat Rizuan, Young C Kim, Jeetain Mittal, Galia T Debelouchina
Nucleic Acids Res. 2022 Dec 9; 50(22): 12702–12722. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1194
PMCID:
PMC9825191
AbstractArticlePDF–6.0M
4.
Visualization and Quantitation of Phase-Separated Droplet Formation by Human HP1α
Madeline M. Keenen, Adam G. Larson, Geeta J. Narlikar
Methods Enzymol. Author manuscript; available in PMC 2022 Apr 8.
Published in final edited form as: Methods Enzymol. 2018; 611: 51–66. Published online 2018 Oct 31. doi: 10.1016/bs.mie.2018.09.034
PMCID:
PMC8989641
AbstractArticlePDF–584K
5.
Depletion of HP1α alters the mechanical properties of MCF7 nuclei
Susav Pradhan, Raoul Solomon, Ankita Gangotra, Gleb E. Yakubov, Geoff R. Willmott, Catherine P. Whitby, Tracy K. Hale, Martin A.K. Williams
Biophys J. 2021 Jul 6; 120(13): 2631–2643. Published online 2021 Jun 2. doi: 10.1016/j.bpj.2021.05.017
PMCID:
PMC8390905
AbstractArticlePDF–2.8M
6.
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Amy R Strom, Ronald J Biggs, Edward J Banigan, Xiaotao Wang, Katherine Chiu, Cameron Herman, Jimena Collado, Feng Yue, Joan C Ritland Politz, Leah J Tait, David Scalzo, Agnes Telling, Mark Groudine, Clifford P Brangwynne, John F Marko, Andrew D Stephens
eLife. 2021; 10: e63972. Published online 2021 Jun 9. doi: 10.7554/eLife.63972
PMCID:
PMC8233041
AbstractArticlePDF–4.1M
7.
Physical modeling of the heritability and maintenance of epigenetic modifications
Sarah H. Sandholtz, Quinn MacPherson, Andrew J. Spakowitz
Proc Natl Acad Sci U S A. 2020 Aug 25; 117(34): 20423–20429. Published online 2020 Aug 10. doi: 10.1073/pnas.1920499117
PMCID:
PMC7456148
AbstractArticlePDF–2.0M
8.
HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry
Jan G Ruppert, Kumiko Samejima, Melpomeni Platani, Oscar Molina, Hiroshi Kimura, A Arockia Jeyaprakash, Shinya Ohta, William C Earnshaw
EMBO J. 2018 Mar 15; 37(6): e97677. Published online 2018 Feb 21. doi: 10.15252/embj.201797677
PMCID:
PMC5852645
AbstractArticlePDF–3.4M
9.
Liquid droplet formation by HP1a suggests a role for phase separation in heterochromatin
Adam G. Larson, Daniel Elnatan, Madeline M. Keenen, Michael J. Trnka, Jonathan B. Johnston, Alma L. Burlingame, David A. Agard, Sy Redding, Geeta J. Narlikar
Nature. Author manuscript; available in PMC 2017 Dec 21.
Published in final edited form as: Nature. 2017 Jul 13; 547(7662): 236–240. Published online 2017 Jun 21. doi: 10.1038/nature22822
PMCID:
PMC5606208
AbstractArticlePDF–1.6M
10.
SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy
Feng-Ming Lin, Santosh Kumar, Jing Ren, Samaneh Karami, Shaymaa Bahnassy, Yue Li, Xiaofeng Zheng, Jing Wang, Tasneem Bawa-Khalfe
Oncotarget. 2016 May 24; 7(21): 30336–30349. Published online 2016 Apr 14. doi: 10.18632/oncotarget.8733
PMCID:
PMC5058684
AbstractArticlePDF–1.7M
11.
Extended string-like binding of the phosphorylated HP1α N-terminal tail to the lysine 9-methylated histone H3 tail
Hideaki Shimojo, Ayumi Kawaguchi, Takashi Oda, Nobuto Hashiguchi, Satoshi Omori, Kei Moritsugu, Akinori Kidera, Kyoko Hiragami-Hamada, Jun-ichi Nakayama, Mamoru Sato, Yoshifumi Nishimura
Sci Rep. 2016; 6: 22527. Published online 2016 Mar 3. doi: 10.1038/srep22527
PMCID:
PMC4776139
AbstractArticlePDF–2.3M
12.
The Spatiotemporal Dynamics of Chromatin Protein HP1α Is Essential for Accurate Chromosome Segregation during Cell Division
Lingluo Chu, Yuda Huo, Xing Liu, Phil Yao, Kelwyn Thomas, Hao Jiang, Tongge Zhu, Guanglan Zhang, Maryam Chaudhry, Gregory Adams, Winston Thompson, Zhen Dou, Changjiang Jin, Ping He, Xuebiao Yao
J Biol Chem. 2014 Sep 19; 289(38): 26249–26262. Published online 2014 Aug 7. doi: 10.1074/jbc.M114.581504
PMCID:
PMC4176231
AbstractArticlePDF–3.1M
13.
Heterochromatin protein 1α: a hallmark of cell proliferation relevant to clinical oncology
Leanne De Koning, Alexia Savignoni, Charlène Boumendil, Haniya Rehman, Bernard Asselain, Xavier Sastre-Garau, Geneviève Almouzni
EMBO Mol Med. 2009 Jun; 1(3): 178–191. doi: 10.1002/emmm.200900022
Correction in:
EMBO Mol Med. 2009 Jul; 1(4): 249.
PMCID:
PMC3378125
AbstractArticlePDF–1.0M
14.
HP1: Heterochromatin binding proteins working the genome
Weihua Zeng, Alexander R. Ball, Jr, Kyoko Yokomori
Epigenetics. Author manuscript; available in PMC 2011 May 29.
Published in final edited form as: Epigenetics. 2010 May 16; 5(4): 287–292. Published online 2010 May 3. doi: 10.4161/epi.5.4.11683
PMCID:
PMC3103764
AbstractArticlePDF–180K
15.
Heterochromatin Protein 1 Is Extensively Decorated with Histone Code-like Post-translational Modifications
Gary LeRoy, John T. Weston, Barry M. Zee, Nicolas L. Young, Mariana D. Plazas-Mayorca, Benjamin A. Garcia
Mol Cell Proteomics. 2009 Nov; 8(11): 2432–2442. Published online 2009 Jun 30. doi: 10.1074/mcp.M900160-MCP200
PMCID:
PMC2773712
AbstractArticlePDF–1.5M
16.
Heterochromatin Protein 1 (HP1) Proteins Do Not Drive Pericentromeric Cohesin Enrichment in Human Cells
Ángel Serrano, Miriam Rodríguez-Corsino, Ana Losada
PLoS One. 2009; 4(4): e5118. Published online 2009 Apr 8. doi: 10.1371/journal.pone.0005118
PMCID:
PMC2662427
AbstractArticlePDF–1.9M
17.
HP1 Proteins Are Essential for a Dynamic Nuclear Response That Rescues the Function of Perturbed Heterochromatin in Primary Human Cells
Rugang Zhang, Song-tao Liu, Wei Chen, Michael Bonner, John Pehrson, Timothy J. Yen, Peter D. Adams
Mol Cell Biol. 2007 Feb; 27(3): 949–962. Published online 2006 Nov 13. doi: 10.1128/MCB.01639-06
PMCID:
PMC1800672
AbstractArticlePDF–1.3M
18.
Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers
Michael T. Zimmermann, Monique M. Williams, Eric W. Klee, Gwen A. Lomberk, Raul Urrutia
Proteins. 2019 Nov; 87(11): 904–916. Published online 2019 Jun 14. doi: 10.1002/prot.25752
PMCID:
PMC6790107
AbstractArticlePDF–3.1M
19.
MacroH2A1.2 Inhibits Prostate Cancer-induced Osteoclastogenesis through Cooperation with HP1α and H1.2
Jinman Kim, Yonghwan Shin, Sunyoung Lee, Miyeong Kim, Vasu Punj, Hongin Shin, Kyunghwan Kim, Jungmin Koh, Daewon Jeong, Woojin An
Oncogene. Author manuscript; available in PMC 2018 Dec 28.
Published in final edited form as: Oncogene. 2018 Oct; 37(43): 5749–5765. Published online 2018 Jun 20. doi: 10.1038/s41388-018-0356-3
PMCID:
PMC6309402
AbstractArticlePDF–1.4M
20.
LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis
Saima Akram, Fengrui Yang, Junying Li, Gregory Adams, Yingying Liu, Xiaoxuan Zhuang, Lingluo Chu, Xu Liu, Nerimah Emmett, Winston Thompson, McKay Mullen, Saravana Muthusamy, Wenwen Wang, Fei Mo, Xing Liu
J Mol Cell Biol. 2018 Dec; 10(6): 527–538. Published online 2018 Jul 16. doi: 10.1093/jmcb/mjy040
PMCID:
PMC6304163
AbstractArticlePDF–1.1M

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