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Select item 45790921.

The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi Apparatus

Wan Yin Lee, Germaine Goh, Joanne Chia, Adrian Boey, Natalia V. Gunko, Frederic Bard

PLoS One. 2015; 10(9): e0138789. Published online 2015 Sep 22. doi: 10.1371/journal.pone.0138789

PMCID:: PMC4579092

Abstract Article PDF–3.3M

Select item 44168442.

Pathogenic Mutations Differentially Affect the Catalytic Activities of the Human B₁₂-processing Chaperone CblC and Increase Futile Redox Cycling

Carmen Gherasim, Markus Ruetz, Zhu Li, Stephanie Hudolin, Ruma Banerjee

J Biol Chem. 2015 May 1; 290(18): 11393–11402. Published online 2015 Mar 25. doi: 10.1074/jbc.M115.637132

PMCID:: PMC4416844

Abstract Article PDF–2.0M

Select item 44844163.

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity

Jessica Frankum, Pavel Moudry, Rachel Brough, Zdenek Hodny, Alan Ashworth, Jiri Bartek, Christopher J. Lord

Oncotarget. 2015 May 10; 6(13): 10746–10758. Published online 2015 Mar 18. doi: 10.18632/oncotarget.3628

PMCID:: PMC4484416

Abstract Article PDF–1.3M

Select item 34098224.

CBL mutations in myeloproliferative neoplasms are also found in the gene’s proline-rich domain and in patients with the V617FJAK2

Paula Aranaz, Cristina Hurtado, Ignacio Erquiaga, Itziar Miguéliz, Cristina Ormazábal, Ion Cristobal, Marina García-Delgado, Francisco Javier Novo, José Luis Vizmanos

Haematologica. 2012 Aug; 97(8): 1234–1241. doi: 10.3324/haematol.2011.052605

PMCID:: PMC3409822

Abstract Article PDF–1.6M

Select item 66022015.

Loss of function Cbl-c mutations in solid tumors

Silvano Rakeem Daniels, Mariya Liyasova, Stephen C. Kales, Marion M. Nau, Philip E. Ryan, Jeffrey E. Green, Stanley Lipkowitz

PLoS One. 2019; 14(7): e0219143. Published online 2019 Jul 1. doi: 10.1371/journal.pone.0219143

PMCID:: PMC6602201

Abstract Article PDF–2.7M

Select item 39007166.

Enigma Prevents Cbl-c-Mediated Ubiquitination and Degradation of RETMEN2A

Stephen C. Kales, Marion M. Nau, Anand S. Merchant, Stanley Lipkowitz

PLoS One. 2014; 9(1): e87116. Published online 2014 Jan 23. doi: 10.1371/journal.pone.0087116

PMCID:: PMC3900716

Abstract Article PDF–1.2M

Select item 34922847.

Cbl-c Ubiquitin Ligase Activity Is Increased via the Interaction of Its RING Finger Domain with a LIM Domain of the Paxillin Homolog, Hic 5

Philip E. Ryan, Stephen C. Kales, Rajgopal Yadavalli, Marion M. Nau, Han Zhang, Stanley Lipkowitz

PLoS One. 2012; 7(11): e49428. Published online 2012 Nov 7. doi: 10.1371/journal.pone.0049428

PMCID:: PMC3492284

Abstract Article PDF–2.0M

Select item 29112988.

The N Terminus of Cbl-c Regulates Ubiquitin Ligase Activity by Modulating Affinity for the Ubiquitin-conjugating Enzyme

Philip E. Ryan, Nina Sivadasan-Nair, Marion M. Nau, Sarah Nicholas, Stanley Lipkowitz

J Biol Chem. 2010 Jul 30; 285(31): 23687–23698. Published online 2010 Jun 4. doi: 10.1074/jbc.M109.091157

PMCID:: PMC2911298

Abstract Article PDF–1.7M

Select item 41402519.

Negative Regulation of NADPH Oxidase 4 by Hydrogen Peroxide-inducible Clone 5 (Hic-5) Protein

Leena P. Desai, Yong Zhou, Aida V. Estrada, Qiang Ding, Guangjie Cheng, James F. Collawn, Victor J. Thannickal

J Biol Chem. 2014 Jun 27; 289(26): 18270–18278. Published online 2014 May 15. doi: 10.1074/jbc.M114.562249

PMCID:: PMC4140251

Abstract Article PDF–1.1M

Select item 12628910.

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

Esther Sook Miin Wong, Chee Wai Fong, Jormay Lim, Permeen Yusoff, Boon Chuan Low, Wallace Y. Langdon, Graeme R. Guy

EMBO J. 2002 Sep 16; 21(18): 4796–4808. doi: 10.1093/emboj/cdf493

PMCID:: PMC126289

Abstract Article PDF–408K

Select item 384477611.

CD2AP and Cbl-3/Cbl-c Constitute a Critical Checkpoint in the Regulation of Ret Signal Transduction

Cynthia C. Tsui, Brian A. Pierchala

J Neurosci. 2008 Aug 27; 28(35): 8789–8800. doi: 10.1523/JNEUROSCI.2738-08.2008

PMCID:: PMC3844776

Abstract Article PDF–806K

Select item 13388012.

Functional Cooperation between c-Cbl and Src-Like Adaptor Protein 2 in the Negative Regulation of T-Cell Receptor Signaling

Michael P. Loreto, Donna M. Berry, C. Jane McGlade

Mol Cell Biol. 2002 Jun; 22(12): 4241–4255. doi: 10.1128/MCB.22.12.4241-4255.2002

PMCID:: PMC133880

Abstract Article PDF–846K

Select item 697099413.

Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation

Sylwia Jones, Peter J. King, Costin N. Antonescu, Michael G. Sugiyama, Amandeep Bhamra, Silvia Surinova, Nicos Angelopoulos, Michael Kragh, Mikkel W. Pedersen, John A. Hartley, Clare E. Futter, Daniel Hochhauser

Sci Rep. 2020; 10: 663. Published online 2020 Jan 20. doi: 10.1038/s41598-019-57153-9

PMCID:: PMC6970994

Abstract Article PDF–5.7M

Select item 352229514.

Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15

Sebastian D. Hayes, Han Liu, Ewan MacDonald, Christopher M. Sanderson, Judy M. Coulson, Michael J. Clague, Sylvie Urbé

J Biol Chem. 2012 Dec 14; 287(51): 43007–43018. Published online 2012 Oct 26. doi: 10.1074/jbc.M112.386938

PMCID:: PMC3522295

Abstract Article PDF–2.6M

Select item 531685515.

The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies

Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina Gonzalez-Pecchi, Qi Qi, Songlin Liu, Philip Webber, Elizabeth McMillan, Lauren Rusnak, Cau Pham, Xiaoqian Chen, Xiulei Mo, Brian Revennaugh, Wei Zhou, Adam Marcus, Sahar Harati, Xiang Chen, Margaret A. Johns, Michael A. White, Carlos S. Moreno, Lee A. D. Cooper, Yuhong Du, Fadlo R. Khuri, Haian Fu

Nat Commun. 2017; 8: 14356. Published online 2017 Feb 16. doi: 10.1038/ncomms14356

Correction in:: Nat Commun. 2017; 8: 15350.

PMCID:: PMC5316855

Abstract Article PDF–4.1M

Select item 339495216.

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson

Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162

PMCID:: PMC3394952

Abstract Article PDF–3.3M

Select item 276528017.

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson

Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109

PMCID:: PMC2765280

Abstract Article PDF–425K

Select item 438092818.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 484876219.

Pooled‐matrix protein interaction screens using Barcode Fusion Genetics

Nozomu Yachie, Evangelia Petsalaki, Joseph C Mellor, Jochen Weile, Yves Jacob, Marta Verby, Sedide B Ozturk, Siyang Li, Atina G Cote, Roberto Mosca, Jennifer J Knapp, Minjeong Ko, Analyn Yu, Marinella Gebbia, Nidhi Sahni, Song Yi, Tanya Tyagi, Dayag Sheykhkarimli, Jonathan F Roth, Cassandra Wong, Louai Musa, Jamie Snider, Yi‐Chun Liu, Haiyuan Yu, Pascal Braun, Igor Stagljar, Tong Hao, Michael A Calderwood, Laurence Pelletier, Patrick Aloy, David E Hill, Marc Vidal, Frederick P Roth

Mol Syst Biol. 2016 Apr; 12(4): 863. Published online 2016 Apr 23. doi: 10.15252/msb.20156660

PMCID:: PMC4848762

Abstract Article PDF–2.8M

Select item 1626720.

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags

Emmanuel Dias Neto, Ricardo Garcia Correa, Sergio Verjovski-Almeida, Marcelo R. S. Briones, Maria Aparecida Nagai, Wilson da Silva, Jr., Marco Antonio Zago, Silvana Bordin, Fernando Ferreira Costa, Gustavo Henrique Goldman, Alex F. Carvalho, Adriana Matsukuma, Gilson S. Baia, David H. Simpson, Adriana Brunstein, Paulo S. L. de Oliveira, Philipp Bucher, C. Victor Jongeneel, Michael J. O'Hare, Fernando Soares, Ricardo R. Brentani, Luis F. L. Reis, Sandro J. de Souza, Andrew J. G. Simpson

Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7): 3491–3496. doi: 10.1073/pnas.97.7.3491

PMCID:: PMC16267

Abstract Article PDF–111K

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PMC Links for Gene (Select 23624) (28)
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E3 ubiquitin ligase RNF121 isoform X4 [Homo sapiens]
E3 ubiquitin ligase RNF121 isoform X4 [Homo sapiens]
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