PMC Links for Gene (Select 23657) - PMC

Links from Gene

Items: 1 to 20 of 129

<< First< Prev

Page of 7

Select item 107610651.

The amino acid transporter SLC7A11 expression in breast cancer

Preyanka Nath, Lutfi H. Alfarsi, Rokaya El-Ansari, Brendah K. Masisi, Busra Erkan, Ali Fakroun, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

Cancer Biol Ther. 2024; 25(1): 2291855. Published online 2023 Dec 10. doi: 10.1080/15384047.2023.2291855

PMCID:: PMC10761065

Abstract Article PDF–2.1M

Select item 106002062.

SLC7A11, a potential immunotherapeutic target in lung adenocarcinoma

Qingqing Shan, Chi Zhang, Yangke Li, Qunying Li, Yifan Zhang, Xue Li, Junqing Shi, Fengying Hu

Sci Rep. 2023; 13: 18302. Published online 2023 Oct 25. doi: 10.1038/s41598-023-45284-z

PMCID:: PMC10600206

Abstract Article PDF–4.8M

Select item 105083843.

Bulk RNA-seq and scRNA-seq reveal SLC7A11, a key regulatory molecule of ferroptosis, is a prognostic-related biomarker and highly related to the immune system in lung adenocarcinoma

Xiaoyu Wu, Sheng Wang, Kaifang Chen

Medicine (Baltimore) 2023 Sep 15; 102(37): e34876. Published online 2023 Sep 15. doi: 10.1097/MD.0000000000034876

PMCID:: PMC10508384

Abstract Article PDF–5.3M

Select item 96997464.

Hypoxia Enhances Glioma Resistance to Sulfasalazine-Induced Ferroptosis by Upregulating SLC7A11 via PI3K/AKT/HIF-1α Axis

Shicheng Sun, Changfa Guo, Taihong Gao, Dengzhen Ma, Xiangsheng Su, Qi Pang, Rui Zhang

Oxid Med Cell Longev. 2022; 2022: 7862430. Published online 2022 Nov 18. doi: 10.1155/2022/7862430

PMCID:: PMC9699746

Abstract Article PDF–5.0M

Select item 96516295.

Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11

Long Zhang, Charbel S. Hobeika, Damir Khabibullin, Deyang Yu, Harilaos Filippakis, Michel Alchoueiry, Yan Tang, Hilaire C. Lam, Peter Tsvetkov, George Georgiou, Candice Lamb, Everett Stone, Pere Puigserver, Carmen Priolo, Elizabeth P. Henske

Proc Natl Acad Sci U S A. 2022 Jul 12; 119(28): e2122840119. Published online 2022 Jul 8. doi: 10.1073/pnas.2122840119

PMCID:: PMC9651629

Abstract Article PDF–2.5M

Select item 92533266.

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

Renhong Yan, Enjun Xie, Yaning Li, Jin Li, Yuanyuan Zhang, Ximin Chi, Xueping Hu, Lei Xu, Tingjun Hou, Brent R. Stockwell, Junxia Min, Qiang Zhou, Fudi Wang

Cell Res. 2022 Jul; 32(7): 687–690. Published online 2022 Mar 29. doi: 10.1038/s41422-022-00642-w

PMCID:: PMC9253326

Article PDF–1.4M

Select item 90954807.

Epigenome-wide association study of alcohol consumption in N = 8161 individuals and relevance to alcohol use disorder pathophysiology: identification of the cystine/glutamate transporter SLC7A11 as a top target

Falk W. Lohoff, Toni-Kim Clarke, Zachary A. Kaminsky, Rosie M. Walker, Mairead L. Bermingham, Jeesun Jung, Stewart W. Morris, Daniel Rosoff, Archie Campbell, Miruna Barbu, Katrin Charlet, Mark Adams, Jisoo Lee, David M. Howard, Emma M. O’Connell, Heather Whalley, David J. Porteous, Andrew M. McIntosh, Kathryn L. Evans

Mol Psychiatry. 2022; 27(3): 1754–1764. Published online 2021 Dec 2. doi: 10.1038/s41380-021-01378-6

PMCID:: PMC9095480

Abstract Article PDF–1.2M

Select item 90760128.

The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma

Li Liu, Jiangtu He, Guifeng Sun, Nan Huang, Zhixuan Bian, Chang Xu, Yue Zhang, Zhongqi Cui, Wenqiang Xu, Fenyong Sun, Chengle Zhuang, Qiuhong Man, Song Gu

Clin Transl Med. 2022 May; 12(5): e778. Published online 2022 May 6. doi: 10.1002/ctm2.778

PMCID:: PMC9076012

Abstract Article PDF–4.3M

Select item 90610459.

A Comprehensive Prognostic and Immune Analysis of Ferroptosis-Related Genes Identifies SLC7A11 as a Novel Prognostic Biomarker in Lung Adenocarcinoma

Li Qian, Fu Wang, Shu-min Lu, Hua-jie Miao, Xin He, Jia Feng, Hua Huang, Rong-feng Shi, Jian-guo Zhang

J Immunol Res. 2022; 2022: 1951620. Published online 2022 Apr 25. doi: 10.1155/2022/1951620

PMCID:: PMC9061045

Abstract Article PDF–2.7M

Select item 839539010.

Glutathione and Related Molecules in Parkinsonism

Masato Asanuma, Ikuko Miyazaki

Int J Mol Sci. 2021 Aug; 22(16): 8689. Published online 2021 Aug 13. doi: 10.3390/ijms22168689

PMCID:: PMC8395390

Abstract Article PDF–672K

Select item 831054711.

Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

Pranavi Koppula, Li Zhuang, Boyi Gan

Protein Cell. 2021 Aug; 12(8): 599–620. Published online 2020 Oct 1. doi: 10.1007/s13238-020-00789-5

PMCID:: PMC8310547

Abstract Article PDF–2.2M

Select item 826116212.

Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization

Nian Liu, JiangLin Zhang, Mingzhu Yin, Hong Liu, Xu Zhang, Jiaoduan Li, Bei Yan, Yeye Guo, Jianda Zhou, Juan Tao, Shuo Hu, Xiang Chen, Cong Peng

Mol Ther. 2021 Jul 7; 29(7): 2321–2334. Published online 2021 Mar 17. doi: 10.1016/j.ymthe.2021.03.013

PMCID:: PMC8261162

Abstract Article PDF–3.5M

Select item 811304113.

PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer

Ting Hong, Guang Lei, Xue Chen, He Li, Xiaoye Zhang, Nayiyuan Wu, Yu Zhao, Yilei Zhang, Jing Wang

Redox Biol. 2021 Jun; 42: 101928. Published online 2021 Mar 5. doi: 10.1016/j.redox.2021.101928

PMCID:: PMC8113041

Abstract Article PDF–9.7M

Select item 801773114.

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11

Subhadip Mukhopadhyay, Douglas E. Biancur, Seth J. Parker, Keisuke Yamamoto, Robert S. Banh, Joao A. Paulo, Joseph D. Mancias, Alec C. Kimmelman

Proc Natl Acad Sci U S A. 2021 Feb 9; 118(6): e2021475118. Published online 2021 Feb 2. doi: 10.1073/pnas.2021475118

PMCID:: PMC8017731

Abstract Article PDF–2.0M

Select item 767996015.

Consensus mutagenesis approach improves the thermal stability of system x_c⁻ transporter, xCT, and enables cryo‐EM analyses

Kazumasa Oda, Yongchan Lee, Pattama Wiriyasermkul, Yoko Tanaka, Mizuki Takemoto, Keitaro Yamashita, Shushi Nagamori, Tomohiro Nishizawa, Osamu Nureki

Protein Sci. 2020 Dec; 29(12): 2398–2407. Published online 2020 Nov 11. doi: 10.1002/pro.3966

PMCID:: PMC7679960

Abstract Article PDF–3.9M

Select item 724269116.

High cell density increases glioblastoma cell viability under glucose deprivation via degradation of the cystine/glutamate transporter xCT (SLC7A11)

Itsuki Yamaguchi, Shige H. Yoshimura, Hironori Katoh

J Biol Chem. 2020 May 15; 295(20): 6936–6945. Published online 2020 Apr 7. doi: 10.1074/jbc.RA119.012213

PMCID:: PMC7242691

Abstract Article PDF–2.7M

Select item 719413517.

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Xiaoguang Liu, Kellen Olszewski, Yilei Zhang, Esther W. Lim, Jiejun Shi, Xiaoshan Zhang, Jie Zhang, Hyemin Lee, Pranavi Koppula, Guang Lei, Li Zhuang, M. James You, Bingliang Fang, Wei Li, Christian M. Metallo, Masha V. Poyurovsky, Boyi Gan

Nat Cell Biol. Author manuscript; available in PMC 2020 Sep 30.

Published in final edited form as: Nat Cell Biol. 2020 Apr; 22(4): 476–486. Published online 2020 Mar 30. doi: 10.1038/s41556-020-0496-x

PMCID:: PMC7194135

Abstract Article PDF–5.2M

Select item 717855018.

Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions

Wenfei Wang, Yi Cai, Guofang Deng, Qianting Yang, Peijun Tang, Meiying Wu, Ziqi Yu, Fan Yang, Jianyong Chen, Oliver Werz, Xinchun Chen

mSphere. 2020 Mar-Apr; 5(2): e00263-20. Published online 2020 Apr 22. doi: 10.1128/mSphere.00263-20

PMCID:: PMC7178550

Abstract Article PDF–1.2M

Select item 706031819.

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

Costanza L. Vallerga, Futao Zhang, Javed Fowdar, Allan F. McRae, Ting Qi, Marta F. Nabais, Qian Zhang, Irfahan Kassam, Anjali K. Henders, Leanne Wallace, Grant Montgomery, Yu-Hsuan Chuang, Steve Horvath, Beate Ritz, Glenda Halliday, Ian Hickie, John B. Kwok, John Pearson, Toni Pitcher, Martin Kennedy, Steven R. Bentley, Peter A. Silburn, Jian Yang, Naomi R. Wray, Simon J. G. Lewis, Tim Anderson, John Dalrymple-Alford, George D. Mellick, Peter M. Visscher, Jacob Gratten

Nat Commun. 2020; 11: 1238. Published online 2020 Mar 6. doi: 10.1038/s41467-020-15065-7

PMCID:: PMC7060318

Abstract Article PDF–1.7M

Select item 695783320.

xCT (SLC7A11) expression confers intrinsic resistance to physical plasma treatment in tumor cells

Sander Bekeschus, Sebastian Eisenmann, Sanjeev Kumar Sagwal, Yana Bodnar, Juliane Moritz, Broder Poschkamp, Ingo Stoffels, Steffen Emmert, Muniswamy Madesh, Klaus-Dieter Weltmann, Thomas von Woedtke, Rajesh Kumar Gandhirajan

Redox Biol. 2020 Feb; 30: 101423. Published online 2020 Jan 3. doi: 10.1016/j.redox.2019.101423

PMCID:: PMC6957833

Abstract Article PDF–2.7M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 129

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity