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Select item 111588111.

Enhanced colitis‐associated colon carcinogenesis in a novel Apc mutant rat

Kazuto Yoshimi, Takuji Tanaka, Akiko Takizawa, Megumi Kato, Masumi Hirabayashi, Tomoji Mashimo, Tadao Serikawa, Takashi Kuramoto

Cancer Sci. 2009 Nov; 100(11): 2022–2027. Published online 2009 Jul 17. doi: 10.1111/j.1349-7006.2009.01287.x

PMCID:: PMC11158811

Abstract Article PDF–953K

Select item 59866572.

Computational development of a molecular-based approach to improve risk stratification of endometrial cancer patients

Federica Torricelli, Davide Nicoli, Riccardo Bellazzi, Alessia Ciarrocchi, Enrico Farnetti, Valentina Mastrofilippo, Raffaella Zamponi, Giovanni Battista La Sala, Bruno Casali, Vincenzo Dario Mandato

Oncotarget. 2018 May 22; 9(39): 25517–25528. Published online 2018 May 22. doi: 10.18632/oncotarget.25354

PMCID:: PMC5986657

Abstract Article PDF–2.2M

Select item 59215143.

Frequent Somatic Mutations of the APC and p53 Genes in Sporadic Ampullary Carcinomas

Yasuo Imai, Hideaki Oda, Naomi Tsurutani, Yoko Nakatsuru, Tohru Inoue, Takatoshi Ishikawa

Jpn J Cancer Res. 1997 Sep; 88(9): 846–854. doi: 10.1111/j.1349-7006.1997.tb00460.x

PMCID:: PMC5921514

Summary PDF–544K

Select item 53051864.

Association between Hepatitis C Virus Infection, p53 Phenotypes, and Gene Variants of Adenomatous Polyposis Coli in Hepatocellular Carcinomas

Leona N Council, Chandrakumar Shanmugam, Esther A Suswam, Venkat R Katkoori, Martine J Heslin, Alex Hanna, Nirag C Jhala, Sooryanarayana Varambally, Upender Manne

J Dig Dis Hepatol. Author manuscript; available in PMC 2017 Feb 13.

Published in final edited form as: J Dig Dis Hepatol. 2016; 2016(5): JDDH-121. Published online 2016 Dec 23.

PMCID:: PMC5305186

Abstract Article PDF–1.1M

Select item 40879995.

Wnt/β-catenin signaling pathway is active in pancreatic development of rat embryo

Qi-Ming Wang, Ye Zhang, Kai-Ming Yang, Hong-Ying Zhou, Hui-Jun Yang

World J Gastroenterol. 2006 Apr 28; 12(16): 2615–2619. Published online 2006 Apr 28. doi: 10.3748/wjg.v12.i16.2615

PMCID:: PMC4087999

Abstract Article PDF–912K

Select item 33245826.

Mitogen-activated protein kinase (MAPK/ERK) regulates adenomatous polyposis coli during growth-factor-induced cell extension

Hector Y. Caro-Gonzalez, Lene N. Nejsum, Kathleen A. Siemers, Thomas A. Shaler, W. James Nelson, Angela I. M. Barth

J Cell Sci. 2012 Mar 1; 125(5): 1247–1258. doi: 10.1242/jcs.095166

PMCID:: PMC3324582

Abstract Article

Select item 31279717.

Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine

Pi-Che Chen, Ming-Hsuan Tsai, Sidney KH Yip, Yeong-Chin Jou, Chi-Fai Ng, Yanning Chen, Xiaoling Wang, Wei Huang, Chun-Liang Tung, Gary CW Chen, Martin MS Huang, Joanna HM Tong, Eing-Ju Song, De-Ching Chang, Cheng-Da Hsu, Ka-Fai To, Cheng-Huang Shen, Michael WY Chan

BMC Med Genomics. 2011; 4: 45. Published online 2011 May 20. doi: 10.1186/1755-8794-4-45

PMCID:: PMC3127971

Abstract Article PDF–1.0M

Select item 18054868.

A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

James M. Amos-Landgraf, Lawrence N. Kwong, Christina M. Kendziorski, Mark Reichelderfer, Jose Torrealba, Jamey Weichert, Jill D. Haag, Kai-Shun Chen, Jordy L. Waller, Michael N. Gould, William F. Dove

Proc Natl Acad Sci U S A. 2007 Mar 6; 104(10): 4036–4041. Published online 2007 Feb 27. doi: 10.1073/pnas.0611690104

PMCID:: PMC1805486

Abstract Article PDF–498K

Select item 999799.

Cell Density and Phosphorylation Control the Subcellular Localization of Adenomatous Polyposis Coli Protein

Fang Zhang, Raymond L. White, Kristi L. Neufeld

Mol Cell Biol. 2001 Dec; 21(23): 8143–8156. doi: 10.1128/MCB.21.23.8143-8156.2001

PMCID:: PMC99979

Abstract Article PDF–7.6M

Select item 4273010.

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

H Kakiuchi, M Watanabe, T Ushijima, M Toyota, K Imai, J H Weisburger, T Sugimura, M Nagao

Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3): 910–914. doi: 10.1073/pnas.92.3.910

PMCID:: PMC42730

Summary Page Browse PDF–1.2M

Select item 1115893411.

APC promoter hypermethylation is an early event in endometrial tumorigenesis

Atanas Ignatov, Joachim Bischoff, Tanja Ignatov, Christa Schwarzenau, Thomas Krebs, Doerthe Kuester, Serban D. Costa, Albert Roessner, Andrzej Semczuk, Regine Schneider‐Stock

Cancer Sci. 2010 Feb; 101(2): 321–327. Published online 2009 Oct 12. doi: 10.1111/j.1349-7006.2009.01397.x

PMCID:: PMC11158934

Abstract Article PDF–317K

Select item 813095912.

Inhibitory effects of a selective prostaglandin E2 receptor antagonist RQ-15986 on inflammation-related colon tumorigenesis in APC-mutant rats

Yohei Shirakami, Takayuki Nakanishi, Noritaka Ozawa, Takayasu Ideta, Takahiro Kochi, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Takuji Tanaka, Masahito Shimizu

PLoS One. 2021; 16(5): e0251942. Published online 2021 May 18. doi: 10.1371/journal.pone.0251942

PMCID:: PMC8130959

Abstract Article PDF–1.0M

Select item 413310113.

APC is an RNA-Binding Protein and its Interactome Provides a Link to Neural Development and Microtubule Assembly

Nicolas Preitner, Jie Quan, Dan W. Nowakowski, Melissa L. Hancock, Jianhua Shi, Joseph Tcherkezian, Tracy L. Young-Pearse, John G. Flanagan

Cell. Author manuscript; available in PMC 2015 Jul 17.

Published in final edited form as: Cell. 2014 Jul 17; 158(2): 368–382. doi: 10.1016/j.cell.2014.05.042

PMCID:: PMC4133101

Abstract Article PDF–2.9M

Select item 356368614.

APC binds intermediate filaments and is required for their reorganization during cell migration

Yasuhisa Sakamoto, Batiste Boëda, Sandrine Etienne-Manneville

J Cell Biol. 2013 Feb 4; 200(3): 249–258. doi: 10.1083/jcb.201206010

PMCID:: PMC3563686

Abstract Article PDF–3.3M

Select item 337378915.

Neurite outgrowth involves adenomatous polyposis coli protein and β-catenin

Violet Votin, W. James Nelson, Angela I. M. Barth

J Cell Sci. Author manuscript; available in PMC 2012 Jun 12.

Published in final edited form as: J Cell Sci. 2005 Dec 15; 118(Pt 24): 5699–5708. Published online 2005 Nov 22. doi: 10.1242/jcs.02679

PMCID:: PMC3373789

Abstract Article PDF–1.5M

Select item 252620916.

A critical role for Apc in hematopoietic stem and progenitor cell survival

Zhijian Qian, Lina Chen, Anthony A. Fernald, Bart O. Williams, Michelle M. Le Beau

J Exp Med. 2008 Sep 1; 205(9): 2163–2175. doi: 10.1084/jem.20080578

PMCID:: PMC2526209

Abstract Article PDF–9.7M

Select item 251736817.

Developmental abnormalities in multiple proliferative tissues of Apc^Min/+ mice

Shaojin You, Masami Ohmori, Maria Marjorette O Peña, Basel Nassri, Jovelyn Quiton, Ziad A Al-Assad, Lucy Liu, Patricia A Wood, Sondra H Berger, ZhiJian Liu, Michael D Wyatt, Robert L Price, Franklin G Berger, William J M Hrushesky

Int J Exp Pathol. 2006 Jun; 87(3): 227–236. doi: 10.1111/j.1365-2613.2006.00477.x

PMCID:: PMC2517368

Abstract Article PDF–566K

Select item 227923318.

Mutational Analysis of Ctnnb1 and Apc in Tumors from Rats Given 1,2-Dimethylhydrazine or 2-Amino-3-methylimidazo[4,5-f]quinoline: Mutational ‘Hotspots’ and the Relative Expression of β-Catenin and c-jun

Carmen A. Blum, Tomoko Tanaka, Xiaoying Zhong, Qingjie Li, Wan-Mohaiza Dashwood, Clifford Pereira, Meirong Xu, Roderick H. Dashwood

Mol Carcinog. Author manuscript; available in PMC 2008 Apr 3.

Published in final edited form as: Mol Carcinog. 2003 Apr; 36(4): 195–203. doi: 10.1002/mc.10112

PMCID:: PMC2279233

Abstract Article PDF–1.3M

Select item 206464719.

APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice

Christine M. Caldwell, Rebecca A. Green, Kenneth B. Kaplan

J Cell Biol. 2007 Sep 24; 178(7): 1109–1120. doi: 10.1083/jcb.200703186

PMCID:: PMC2064647

Abstract Article PDF–7.4M

Select item 186718820.

Genetic and Immunohistochemical Analysis of Pancreatic Acinar Cell Carcinoma : Frequent Allelic Loss on Chromosome 11p and Alterations in the APC/β-Catenin Pathway

Susan C. Abraham, Tsung-Teh Wu, Ralph H. Hruban, Jae-Hyuk Lee, Charles J. Yeo, Kevin Conlon, Murray Brennan, John L. Cameron, David S. Klimstra

Am J Pathol. 2002 Mar; 160(3): 953–962. doi: 10.1016/s0002-9440(10)64917-6

PMCID:: PMC1867188

Abstract Article PDF–694K

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PMC Links for Gene (Select 24205) (74)
PMC
Human DNA sequence from clone RP4-735C1 on chromosome 1, complete sequence
Human DNA sequence from clone RP4-735C1 on chromosome 1, complete sequence
gi|15131467|emb|AL158847.22|

Nucleotide
Homo sapiens cDNA FLJ51755 complete cds, highly similar to Glutathione S-transfe...
Homo sapiens cDNA FLJ51755 complete cds, highly similar to Glutathione S-transferase Mu 3 (EC 2.5.1.18)
gi|194385553|dbj|AK304300.1|

Nucleotide
Homo sapiens glutathione S-transferase mu 3 (brain), mRNA (cDNA clone MGC:3310 I...
Homo sapiens glutathione S-transferase mu 3 (brain), mRNA (cDNA clone MGC:3310 IMAGE:3509784), complete cds
gi|38014180|gb|BC000088.2|

Nucleotide
Homo sapiens KIAA0185 mRNA, complete cds
Homo sapiens KIAA0185 mRNA, complete cds
gi|1136429|dbj|D80007.1|

Nucleotide

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