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Select item 99945131.

Role and mechanism of alpa1-antitrypsin in polycystic ovary syndrome

Shouxi Pan, Yilihaer Aizezi, Honglei Wang, Yingli Lu, Baigong Xue

Saudi Med J. 2022 Dec; 43(12): 1309–1316. doi: 10.15537/smj.2022.43.12.20210398

PMCID:: PMC9994513

Abstract Article PDF–1.7M

Select item 46544622.

Alpha1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis

Colm B. Collins, Carol M. Aherne, Stefan F. Ehrentraut, Mark E. Gerich, Eóin N. McNamee, Martine C. McManus, Matthew D.P. Lebsack, Paul Jedlicka, Tania Azam, Edwin F. de Zoeten, Charles A. Dinarello, Jesús Rivera-Nieves

Inflamm Bowel Dis. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Inflamm Bowel Dis. 2013 Aug; 19(9): 1964–1973. doi: 10.1097/MIB.0b013e31829292aa

PMCID:: PMC4654462

Abstract Article PDF–838K

Select item 31369583.

Lung Disease Associated with α₁-Antitrypsin Deficiency

Rubin M. Tuder, Sabina M. Janciauskiene, Irina Petrache

Proc Am Thorac Soc. 2010 Nov 1; 7(6): 381–386. doi: 10.1513/pats.201002-020AW

PMCID:: PMC3136958

Abstract Article PDF–594K

Select item 22593614.

Gene expression profiles in primary pancreatic tumors and metastatic lesions of Ela-c-myc transgenic mice

Archana Thakur, Aliccia Bollig, Jiusheng Wu, Dezhong J Liao

Mol Cancer. 2008; 7: 11. Published online 2008 Jan 24. doi: 10.1186/1476-4598-7-11

PMCID:: PMC2259361

Abstract Article PDF–628K

Select item 18388315.

Proteomic analysis of the serum in patients with idiopathic pulmonary arterial hypertension

Min Yu, Xing-xiang Wang, Fu-rong Zhang, Yun-peng Shang, Yu-xi Du, Hong-juan Chen, Jun-zhu Chen

J Zhejiang Univ Sci B. 2007 Apr; 8(4): 221–227. doi: 10.1631/jzus.2007.B0221

PMCID:: PMC1838831

Abstract Article PDF–401K

Select item 53252076.

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury

Nuria Maicas, Johan van der Vlag, Janin Bublitz, Sandrine Florquin, Marinka Bakker-van Bebber, Charles A. Dinarello, Vivienne Verweij, Roos Masereeuw, Leo A. Joosten, Luuk B. Hilbrands

PLoS One. 2017; 12(2): e0168981. Published online 2017 Feb 24. doi: 10.1371/journal.pone.0168981

PMCID:: PMC5325207

Abstract Article PDF–2.8M

Select item 49070147.

Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection

Pedro Ayala, Manuel Meneses, Pablo Olmos, Rebeca Montalva, Karla Droguett, Mariana Ríos, Gisella Borzone

Respir Res. 2016; 17: 71. Published online 2016 Jun 14. doi: 10.1186/s12931-016-0379-7

PMCID:: PMC4907014

Abstract Article PDF–3.2M

Select item 40325878.

Serum concentration of alpha-1 antitrypsin is significantly higher in colorectal cancer patients than in healthy controls

Sergio Pérez-Holanda, Ignacio Blanco, Manuel Menéndez, Luis Rodrigo

BMC Cancer. 2014; 14: 355. Published online 2014 May 21. doi: 10.1186/1471-2407-14-355

PMCID:: PMC4032587

Abstract Article PDF–220K

Select item 33149049.

Structural Dynamics Associated with Intermediate Formation in an Archetypal Conformational Disease

Mun Peak Nyon, Lakshmi Segu, Lisa D. Cabrita, Géraldine R. Lévy, John Kirkpatrick, Benoit D. Roussel, Anathe O.M. Patschull, Tracey E. Barrett, Ugo I. Ekeowa, Richard Kerr, Christopher A. Waudby, Noor Kalsheker, Marian Hill, Konstantinos Thalassinos, David A. Lomas, John Christodoulou, Bibek Gooptu

Structure. 2012 Mar 7; 20-135(3-3): 504–512. doi: 10.1016/j.str.2012.01.012

PMCID:: PMC3314904

Abstract Article PDF–1.0M

Select item 318534510.

Molecular basis of α₁-antitrypsin deficiency revealed by the structure of a domain-swapped trimer

Masayuki Yamasaki, Timothy J Sendall, Mary C Pearce, James C Whisstock, James A Huntington

EMBO Rep. 2011 Oct; 12(10): 1011–1017. Published online 2011 Sep 9. doi: 10.1038/embor.2011.171

PMCID:: PMC3185345

Abstract Article PDF–1.1M

Select item 315908911.

Genetic Influences on Asthma Susceptibility in the Developing Lung

Nicole Carpe, Isabel Mandeville, Leslie Ribeiro, Andre Ponton, James G. Martin, Alvin T. Kho, Jen-Hwa Chu, Kelan Tantisira, Scott T. Weiss, Benjamin A. Raby, Feige Kaplan

Am J Respir Cell Mol Biol. 2010 Dec; 43(6): 720–730. Published online 2010 Jan 29. doi: 10.1165/rcmb.2009-0412OC

PMCID:: PMC3159089

Abstract Article PDF–1.5M

Select item 285277912.

Alpha-1-antitrypsin phenotypes in adult liver disease patients

Aleksandra Topic, Tamara Alempijevic, Aleksandra Sokic Milutinovic, Nada Kovacevic

Ups J Med Sci. 2009 Dec; 114(4): 228–234. Published online 2009 Dec 8. doi: 10.3109/03009730903243472

PMCID:: PMC2852779

Abstract Article PDF–75K

Select item 284360413.

Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study

Karin F Kok, René H te Morsche, Martijn GH van Oijen, Joost PH Drenth

BMC Gastroenterol. 2010; 10: 22. Published online 2010 Feb 20. doi: 10.1186/1471-230X-10-22

PMCID:: PMC2843604

Abstract Article PDF–343K

Select item 466946914.

Hepatic steatosis depresses alpha-1-antitrypsin levels in human and rat acute pancreatitis

Qian Wang, Jianjun Du, Pengfei Yu, Bin Bai, Zhanwei Zhao, Shiqi Wang, Junjie Zhu, Quanxin Feng, Yun Gao, Qingchuan Zhao, Chaoxu Liu

Sci Rep. 2015; 5: 17833. Published online 2015 Dec 4. doi: 10.1038/srep17833

PMCID:: PMC4669469

Abstract Article PDF–1.4M

Select item 399057215.

Active Trafficking of Alpha 1 Antitrypsin across the Lung Endothelium

Angelia D. Lockett, Mary Beth Brown, Nieves Santos-Falcon, Natalia I. Rush, Houssam Oueini, Amber J. Oberle, Esther Bolanis, Miryam A. Fragoso, Daniela N. Petrusca, Karina A. Serban, Kelly S. Schweitzer, Robert G. Presson Jr., Michael Campos, Irina Petrache

PLoS One. 2014; 9(4): e93979. Published online 2014 Apr 17. doi: 10.1371/journal.pone.0093979

PMCID:: PMC3990572

Abstract Article PDF–1.1M

Select item 157384616.

Mechanism of kinin release during experimental acute pancreatitis in rats: evidence for pro- as well as anti-inflammatory roles of oedema formation

Thomas Griesbacher, Irmgard Rainer, Beate Tiran, Edwin Fink, Fred Lembeck, Bernhard A Peskar

Br J Pharmacol. 2003 May; 139(2): 299–308. Published online 2003 May 29. doi: 10.1038/sj.bjp.0705247

PMCID:: PMC1573846

Abstract Article PDF–195K

Select item 371124317.

GENETIC MODIFIERS OF LIVER DISEASE IN CYSTIC FIBROSIS

Jaclyn R. Bartlett, Kenneth J. Friedman, Simon C. Ling, Rhonda G. Pace, Scott C. Bell, Billy Bourke, Giuseppe Castaldo, Carlo Castellani, Marco Cipolli, Carla Colombo, John L. Colombo, Dominique Debray, Adriana Fernandez, Florence Lacaille, Milan Macek, Jr., Marion Rowland, Francesco Salvatore, Christopher J. Taylor, Claire Wainwright, Michael Wilschanski, Dana Zemková, William B. Hannah, M. James Phillips, Mary Corey, Julian Zielenski, Ruslan Dorfman, Yunfei Wang, Fei Zou, Lawrence M. Silverman, Mitchell L. Drumm, Fred A. Wright, Ethan M. Lange, Peter R. Durie, Michael R. Knowles

JAMA. Author manuscript; available in PMC 2013 Jul 15.

Published in final edited form as: JAMA. 2009 Sep 9; 302(10): 1076–1083. doi: 10.1001/jama.2009.1295

PMCID:: PMC3711243

Abstract Article PDF–342K

Select item 369123818.

SERPINA2 Is a Novel Gene with a Divergent Function from SERPINA1

Patrícia Isabel Marques, Zélia Ferreira, Manuella Martins, Joana Figueiredo, Diana Isabel Silva, Patrícia Castro, Ramiro Morales-Hojas, Joana Simões-Correia, Susana Seixas

PLoS One. 2013; 8(6): e66889. Published online 2013 Jun 24. doi: 10.1371/journal.pone.0066889

PMCID:: PMC3691238

Abstract Article PDF–6.7M

Select item 160368519.

Trypsin-2 Degrades Human Type II Collagen and Is Expressed and Activated in Mesenchymally Transformed Rheumatoid Arthritis Synovitis Tissue

Mathias Stenman, Mari Ainola, Leena Valmu, Anders Bjartell, Guofeng Ma, Ulf-Håkan Stenman, Timo Sorsa, Reijo Luukkainen, Yrjö T. Konttinen

Am J Pathol. 2005 Oct; 167(4): 1119–1124. doi: 10.1016/S0002-9440(10)61200-X

PMCID:: PMC1603685

Abstract Article PDF–728K

Select item 118826820.

Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity

Roman Szabo, Sarah Netzel-Arnett, John P. Hobson, Toni M. Antalis, Thomas H. Bugge

Biochem J. 2005 Aug 15; 390(Pt 1): 231–242. Prepublished online 2005 Apr 27. Published online 2005 Aug 9. doi: 10.1042/BJ20050299

PMCID:: PMC1188268

Abstract Article PDF–917K

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