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Select item 104328701.

The expanding universe of NUTM1 fusions in pediatric cancer

Rosane Charlab, Rebecca Racz

Clin Transl Sci. 2023 Aug; 16(8): 1331–1339. Published online 2023 May 14. doi: 10.1111/cts.13535

PMCID:: PMC10432870

Abstract Article PDF–1.1M

Select item 84786412.

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

Judith M. Boer, Maria Grazia Valsecchi, Femke M. Hormann, Željko Antić, Marketa Zaliova, Claire Schwab, Giovanni Cazzaniga, Chloé Arfeuille, Hélène Cavé, Andishe Attarbaschi, Sabine Strehl, Gabriele Escherich, Toshihiko Imamura, Kentaro Ohki, Tanja A. Grüber, Rosemary Sutton, Agata Pastorczak, Tim Lammens, Frédéric Lambert, Chi Kong Li, Enrique Carrillo de Santa Pau, Steve Hoffmann, Anja Möricke, Christine J. Harrison, Monique L. Den Boer, Paola De Lorenzo, Ronald W. Stam, Anke K. Bergmann, Rob Pieters

Leukemia. 2021; 35(10): 2978–2982. Published online 2021 Jul 1. doi: 10.1038/s41375-021-01333-y

PMCID:: PMC8478641

Article PDF–1008K

Select item 81943663.

NUTM1-rearranged neoplasia: a multi-institution experience yields novel fusion partners and expands the histologic spectrum

Todd M. Stevens, Diana Morlote, Joanne Xiu, Jeffrey Swensen, Margaret Brandwein-Weber, Markku M. Miettinen, Zoran Gatalica, Julia A. Bridge

Mod Pathol. Author manuscript; available in PMC 2021 Jun 11.

Published in final edited form as: Mod Pathol. 2019 Jun; 32(6): 764–773. Published online 2019 Feb 5. doi: 10.1038/s41379-019-0206-z

PMCID:: PMC8194366

Abstract Article PDF–1.0M

Select item 79159104.

Challenges and Opportunities in NUT Carcinoma Research

Bin Gu, Maxwell C. Hakun

Genes (Basel) 2021 Feb; 12(2): 235. Published online 2021 Feb 5. doi: 10.3390/genes12020235

PMCID:: PMC7915910

Abstract Article PDF–8.8M

Select item 58934075.

NUTM1 GENE FUSIONS CHARACTERIZE A SUBSET OF UNDIFFERENTIATED SOFT TISSUE AND VISCERAL TUMORS

Brendan C. Dickson, Yun-Shao Sung, Marc K. Rosenblum, Victor E. Reuter, Mohammed Harb, Jay S. Wunder, David Swanson, Cristina R. Antonescu

Am J Surg Pathol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Am J Surg Pathol. 2018 May; 42(5): 636–645. doi: 10.1097/PAS.0000000000001021

PMCID:: PMC5893407

Abstract Article PDF–2.2M

Select item 45608686.

NUT expression in primary lung tumours

Marius Lund-Iversen, Krystyna Kotanska Grøholt, Åslaug Helland, Elin Borgen, Odd Terje Brustugun

Diagn Pathol. 2015; 10: 156. Published online 2015 Sep 5. doi: 10.1186/s13000-015-0395-9

PMCID:: PMC4560868

Abstract Article PDF–1.0M

Select item 44438477.

Primary Pulmonary NUT-Midline Carcinoma: Clinical, Radiographic, and Pathologic Characterization

Lynette M. Sholl, Mizuki Nishino, Saraswati Pokharel, Mari Mino-Kenudson, Christopher A. French, Pasi A. Janne, Christopher Lathan

J Thorac Oncol. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: J Thorac Oncol. 2015 Jun; 10(6): 951–959. doi: 10.1097/JTO.0000000000000545

PMCID:: PMC4443847

Abstract Article PDF–1.0M

Select item 33081278.

NUT Rearrangement is Uncommon in Human Thymic Epithelial Tumors

Iacopo Petrini, Christopher A. French, Arun Rajan, Michael J. Cameron, Elaine Jaffe, Paolo A. Zucali, Jianwu Xie, Yisong Wang, Giuseppe Giaccone

J Thorac Oncol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: J Thorac Oncol. 2012 Apr; 7(4): 744–750. doi: 10.1097/JTO.0b013e3182460f8f

PMCID:: PMC3308127

Abstract Article PDF–3.2M

Select item 98709039.

Structural mechanism of BRD4-NUT and p300 bipartite interaction in propagating aberrant gene transcription in chromatin in NUT carcinoma

Di Yu, Yingying Liang, Claudia Kim, Anbalagan Jaganathan, Donglei Ji, Xinye Han, Xuelan Yang, Yanjie Jia, Ruirui Gu, Chunyu Wang, Qiang Zhang, Ka Lung Cheung, Ming-Ming Zhou, Lei Zeng

Nat Commun. 2023; 14: 378. Published online 2023 Jan 24. doi: 10.1038/s41467-023-36063-5

PMCID:: PMC9870903

Abstract Article PDF–3.8M

Select item 791421710.

Supercharging BRD4 with NUT in carcinoma

Kyle P. Eagen, Christopher A. French

Oncogene. Author manuscript; available in PMC 2021 Jul 15.

Published in final edited form as: Oncogene. 2021 Feb; 40(8): 1396–1408. Published online 2021 Jan 15. doi: 10.1038/s41388-020-01625-0

PMCID:: PMC7914217

Abstract Article PDF–1.2M

Select item 766997111.

YAP1-NUTM1 Gene Fusion in Porocarcinoma of the External Auditory Canal

Abbas Agaimy, Lars Tögel, Florian Haller, Johannes Zenk, Joachim Hornung, Bruno Märkl

Head Neck Pathol. 2020 Dec; 14(4): 982–990. Published online 2020 May 20. doi: 10.1007/s12105-020-01173-9

PMCID:: PMC7669971

Abstract Article PDF–3.0M

Select item 688182112.

CIC-NUTM1 fusion: A case which expands the spectrum of NUT-rearranged epithelioid malignancies

Inga-Marie Schaefer, Paola Dal Cin, Latrice M. Landry, Christopher D. M. Fletcher, Glenn J. Hanna, Christopher A. French

Genes Chromosomes Cancer. Author manuscript; available in PMC 2019 Nov 28.

Published in final edited form as: Genes Chromosomes Cancer. 2018 Sep; 57(9): 446–451. Published online 2018 Aug 14. doi: 10.1002/gcc.3

PMCID:: PMC6881821

Abstract Article PDF–2.8M

Select item 537822513.

Complex chromosomal rearrangements by single catastrophic pathogenesis in NUT midline carcinoma

J.-K. Lee, S. Louzada, Y. An, S. Y. Kim, S. Kim, J. Youk, S. Park, S. H. Koo, B. Keam, Y. K. Jeon, J.-L. Ku, F. Yang, T. M. Kim, Y. S. Ju

Ann Oncol. 2017 Apr; 28(4): 890–897. Published online 2017 Feb 14. doi: 10.1093/annonc/mdw686

PMCID:: PMC5378225

Abstract Article PDF–1.5M

Select item 504774414.

The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns

Barry M. Zee, Amy B. Dibona, Artyom A. Alekseyenko, Christopher A. French, Mitzi I. Kuroda

PLoS One. 2016; 11(10): e0163820. Published online 2016 Oct 3. doi: 10.1371/journal.pone.0163820

PMCID:: PMC5047744

Abstract Article PDF–1.7M

Select item 452673515.

The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains

Artyom A. Alekseyenko, Erica M. Walsh, Xin Wang, Adlai R. Grayson, Peter T. Hsi, Peter V. Kharchenko, Mitzi I. Kuroda, Christopher A. French

Genes Dev. 2015 Jul 15; 29(14): 1507–1523. doi: 10.1101/gad.267583.115

PMCID:: PMC4526735

Abstract Article PDF–793K

Select item 431703516.

Mechanistic Analysis of the Role of Bromodomain-containing Protein 4 (BRD4) in BRD4-NUT Oncoprotein-induced Transcriptional Activation

Ranran Wang, Jianxin You

J Biol Chem. 2015 Jan 30; 290(5): 2744–2758. Published online 2014 Dec 15. doi: 10.1074/jbc.M114.600759

PMCID:: PMC4317035

Abstract Article PDF–3.6M

Select item 314935717.

Perturbation of BRD4 Protein Function by BRD4-NUT Protein Abrogates Cellular Differentiation in NUT Midline Carcinoma

Junpeng Yan, Jason Diaz, Jing Jiao, Ranran Wang, Jianxin You

J Biol Chem. 2011 Aug 5; 286(31): 27663–27675. Published online 2011 Jun 7. doi: 10.1074/jbc.M111.246975

PMCID:: PMC3149357

Abstract Article PDF–3.1M

Select item 173610518.

Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro

N Haruki, K Kawaguchi, S Eichenberger, P Massion, A Gonzalez, A Gazdar, J Minna, D Carbone, T Dang

J Med Genet. 2005 Jul; 42(7): 558–564. doi: 10.1136/jmg.2004.029686

PMCID:: PMC1736105

Summary PDF–283K

Select item 671538319.

Recurrent YAP1-MAML2 and YAP1-NUTM1 fusions in poroma and porocarcinoma

Shigeki Sekine, Tohru Kiyono, Eijitsu Ryo, Reiko Ogawa, Susumu Wakai, Hitoshi Ichikawa, Koyu Suzuki, Satoru Arai, Koji Tsuta, Mitsuaki Ishida, Yuko Sasajima, Naoki Goshima, Naoya Yamazaki, Taisuke Mori

J Clin Invest. 2019 Sep 3; 129(9): 3827–3832. Published online 2019 Aug 12. doi: 10.1172/JCI126185

PMCID:: PMC6715383

Abstract Article PDF–8.9M

Select item 294405120.

Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains

Nicolas Reynoird, Brian E Schwartz, Manuela Delvecchio, Karin Sadoul, David Meyers, Chandrani Mukherjee, Cécile Caron, Hiroshi Kimura, Sophie Rousseaux, Philip A Cole, Daniel Panne, Christopher A French, Saadi Khochbin

EMBO J. 2010 Sep 1; 29(17): 2943–2952. Published online 2010 Jul 30. doi: 10.1038/emboj.2010.176

PMCID:: PMC2944051

Abstract Article PDF–1.6M

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