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Items: 1 to 20 of 47

1.
Beyond Impairment of Virion Infectivity: New Activities of the Anti-HIV Host Cell Factor SERINC5
Samy Sid Ahmed, Kathrin Bajak, Oliver T. Fackler
Viruses. 2024 Feb; 16(2): 284. Published online 2024 Feb 12. doi: 10.3390/v16020284
PMCID:
PMC10892966
AbstractArticlePDF–1.6M
2.
Relative resistance of patient-derived envelope sequences to SERINC5-mediated restriction of HIV-1 infectivity
Emmanuel Nkuwi, George P. Judicate, Toong Seng Tan, Godfrey Barabona, Mako Toyoda, Bruno Sunguya, Doreen Kamori, Takamasa Ueno
J Virol. 2023 Oct; 97(10): e00823-23. Published online 2023 Sep 28. doi: 10.1128/jvi.00823-23
PMCID:
PMC10617508
AbstractArticlePDF–974K
3.
SERINC5 Mediates a Postintegration Block to HIV-1 Gene Expression in Macrophages
Pavitra Ramdas, Ajit Chande
mBio. 2023 Mar-Apr; 14(2): e00166-23. Published online 2023 Mar 28. doi: 10.1128/mbio.00166-23
Correction in:
mBio. 2023 Jul-Aug; 14(4): e01222-23.
PMCID:
PMC10127607
AbstractArticlePDF–3.0M
4.
Restriction of Influenza A Virus by SERINC5
Kin Kui Lai, James B. Munro, Guoli Shi, Saliha Majdoul, Alex A. Compton, Alan Rein
mBio. 2022 Nov-Dec; 13(6): e02923-22. Published online 2022 Nov 21. doi: 10.1128/mbio.02923-22
PMCID:
PMC9765469
AbstractArticlePDF–2.2M
5.
SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane
Gokul Raghunath, Yen-Cheng Chen, Mariana Marin, Hui Wu, Gregory B. Melikyan
Viruses. 2022 Aug; 14(8): 1636. Published online 2022 Jul 27. doi: 10.3390/v14081636
PMCID:
PMC9332783
AbstractArticlePDF–1.8M
6.
Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity
William E. Diehl, Mehmet H. Guney, Teresa Vanzo, Pyae P. Kyawe, Judith M. White, Massimo Pizzato, Jeremy Luban
Viruses. 2021 Jul; 13(7): 1279. Published online 2021 Jun 30. doi: 10.3390/v13071279
PMCID:
PMC8310182
AbstractArticlePDF–8.3M
7.
Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters
Yen-Cheng Chen, Chetan Sood, Mariana Marin, Jesse Aaron, Enrico Gratton, Khalid Salaita, Gregory B. Melikyan
ACS Nano. Author manuscript; available in PMC 2021 Jul 12.
Published in final edited form as: ACS Nano. 2020 Sep 22; 14(9): 10929–10943. Published online 2020 Jun 1. doi: 10.1021/acsnano.0c02699
PMCID:
PMC8274448
AbstractArticlePDF–2.1M
8.
SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles
Virginia Pierini, Lara Gallucci, Christina M. Stürzel, Frank Kirchhoff, Oliver T. Fackler
J Virol. 2021 May; 95(9): e02372-20. Prepublished online 2021 Feb 17. Published online 2021 Apr 12. doi: 10.1128/JVI.02372-20
PMCID:
PMC8104095
AbstractArticlePDF–3.2M
9.
SERINC5 Is an Unconventional HIV Restriction Factor That Is Upregulated during Myeloid Cell Differentiation
Ariane Zutz, Christian Schölz, Stephanie Schneider, Virginia Pierini, Maximilian Münchhoff, Kathrin Sutter, Georg Wittmann, Ulf Dittmer, Rika Draenert, Johannes R. Bogner, Oliver T. Fackler, Oliver T. Keppler
J Innate Immun. 2020 Sep; 12(5): 399–409. Published online 2020 Jan 14. doi: 10.1159/000504888
PMCID:
PMC7900780
AbstractArticlePDF–4.1M
10.
Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals
Mako Toyoda, Doreen Kamori, Toong Seng Tan, Kageaki Goebuchi, Jun Ohashi, Jonathan Carlson, Ai Kawana-Tachikawa, Hiroyuki Gatanaga, Shinichi Oka, Massimo Pizzato, Takamasa Ueno
Sci Rep. 2020; 10: 19416. Published online 2020 Nov 10. doi: 10.1038/s41598-020-76375-w
PMCID:
PMC7656250
AbstractArticlePDF–1.1M
11.
Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5
Sebastian Molnar, Lindsay Wieczorek, Michelle Zemil, Bianca Schulte, Elizabeth Martinez, Syna Gift, Lan Tang, Hendrik Streeck, Robert A. Gramzinski, Nelson L. Michael, Gordon Joyce, Victoria R. Polonis
MAbs. 2020 Jan-Dec; 12(1): 1802187. Published online 2020 Aug 23. doi: 10.1080/19420862.2020.1802187
PMCID:
PMC7531522
AbstractArticlePDF–4.0M
12.
Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor
Vânia Passos, Thomas Zillinger, Nicoletta Casartelli, Amelie S. Wachs, Shuting Xu, Angelina Malassa, Katja Steppich, Hildegard Schilling, Sergej Franz, Daniel Todt, Eike Steinmann, Kathrin Sutter, Ulf Dittmer, Jens Bohne, Olivier Schwartz, Winfried Barchet, Christine Goffinet
J Virol. 2019 Dec 15; 93(24): e01221-19. Prepublished online 2019 Oct 9. Published online 2019 Nov 26. doi: 10.1128/JVI.01221-19
PMCID:
PMC6880170
AbstractArticlePDF–1.6M
13.
An N-Glycosylated Form of SERINC5 Is Specifically Incorporated into HIV-1 Virions
Shilpi Sharma, Mary K. Lewinski, John Guatelli
J Virol. 2018 Nov 15; 92(22): e00753-18. Prepublished online 2018 Aug 29. Published online 2018 Oct 29. doi: 10.1128/JVI.00753-18
PMCID:
PMC6206478
AbstractArticlePDF–2.1M
14.
Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction
Xianfeng Zhang, Tao Zhou, Jie Yang, Yumei Lin, Jing Shi, Xihe Zhang, Dylan A. Frabutt, Xiangwei Zeng, Sunan Li, Patrick J. Venta, Yong-Hui Zheng
J Virol. 2017 May 15; 91(10): e00137-17. Prepublished online 2017 Mar 8. Published online 2017 Apr 28. doi: 10.1128/JVI.00137-17
PMCID:
PMC5411613
AbstractArticlePDF–1.4M
15.
Genome-wide analyses of borderline personality features
GH Lubke, C Laurin, N Amin, JJ Hottenga, G Willemsen, G van Grootheest, A Abdellaoui, LC Karssen, BA Oostra, CM van Duijn, BWJH Penninx, DI Boomsma
Mol Psychiatry. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Mol Psychiatry. 2014 Aug; 19(8): 923–929. Published online 2013 Aug 27. doi: 10.1038/mp.2013.109
PMCID:
PMC3872258
AbstractArticlePDF–1.4M
16.
Nef enhances HIV-1 replication and infectivity independently of SERINC5 in CEM T cells
Peter W. Ramirez, Thomas Vollbrecht, Francisco M. Acosta, Marissa Suarez, Aaron O. Angerstein, Jared Wallace, Ryan M. O’ Connell, John Guatelli
Virology. Author manuscript; available in PMC 2023 Sep 7.
Published in final edited form as: Virology. 2023 Jan; 578: 154–162. Published online 2022 Dec 23. doi: 10.1016/j.virol.2022.12.008
PMCID:
PMC10484624
AbstractArticlePDF–1.2M
17.
Nef homodimers down-regulate SERINC5 by AP-2–mediated endocytosis to promote HIV-1 infectivity
Ryan P. Staudt, Thomas E. Smithgall
J Biol Chem. 2020 Nov 13; 295(46): 15540–15552. Published online 2020 Sep 1. doi: 10.1074/jbc.RA120.014668
PMCID:
PMC7667984
AbstractArticlePDF–2.9M
18.
HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy
Amanda E. Ward, Volker Kiessling, Owen Pornillos, Judith M. White, Barbie K. Ganser-Pornillos, Lukas K. Tamm
J Biol Chem. 2020 Nov 6; 295(45): 15183–15195. Published online 2020 Aug 11. doi: 10.1074/jbc.RA120.014466
PMCID:
PMC7650252
AbstractArticlePDF–2.9M
19.
SERINC5 Inhibits HIV-1 Infectivity by Altering the Conformation of gp120 on HIV-1 Particles
Austin Featherstone, Christopher Aiken
J Virol. 2020 Oct; 94(20): e00594-20. Prepublished online 2020 Aug 12. Published online 2020 Sep 29. doi: 10.1128/JVI.00594-20
PMCID:
PMC7527050
AbstractArticlePDF–747K
20.
Sensitivity to Monoclonal Antibody 447–52D and an Open Env Trimer Conformation Correlate Poorly with Inhibition of HIV-1 Infectivity by SERINC5
Aaron O. Angerstein, Charlotte A. Stoneham, Peter W. Ramirez, John C. Guatelli, Thomas Vollbrecht
Virology. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Virology. 2020 Sep; 548: 73–81. Published online 2020 Jun 17. doi: 10.1016/j.virol.2020.06.007
Correction in:
Virology. 2021 Feb 10
PMCID:
PMC7447835
AbstractArticlePDF–656K

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