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Select item 91530121.

HGAL inhibits lymphoma dissemination by interacting with multiple cytoskeletal proteins

Xiaoyu Jiang, XiaoQing Lu, Andrew J. Gentles, Dekuang Zhao, Seth A. Wander, Yu Zhang, Yasodha Natkunam, Joyce Slingerland, Isildinha M. Reis, Brian Rabinovich, Midhat H. Abdulreda, Vincent T. Moy, Izidore S. Lossos

Blood Adv. 2021 Dec 14; 5(23): 5072–5085. Published online 2021 Dec 3. doi: 10.1182/bloodadvances.2021004304

PMCID:: PMC9153012

Abstract Article PDF–2.5M

Select item 43041102.

HGAL localization to cell membrane regulates B-cell receptor signaling

Xiaoqing Lu, Renaud Sicard, Xiaoyu Jiang, Jessica N. Stockus, George McNamara, Midhat Abdulreda, Vincent T. Moy, Ralf Landgraf, Izidore S. Lossos

Blood. 2015 Jan 22; 125(4): 649–657. Prepublished online 2014 Nov 7. doi: 10.1182/blood-2014-04-571331

PMCID:: PMC4304110

Abstract Article

Select item 30972723.

Germinal Center Specific Protein HGAL Directly Interacts with Both Myosin and Actin and Increases the Binding of Myosin to Actin

Xiaoqing Lu, Katarzyna Kazmierczak, Xiaoyu Jiang, Michelle Jones, James Watt, David M. Helfman, Jeffrey R. Moore, Danuta Szczesna-Cordary, Izidore S. Lossos

FEBS J. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: FEBS J. 2011 Jun; 278(11): 1922–1931. Published online 2011 Apr 20. doi: 10.1111/j.1742-4658.2011.08109.x

PMCID:: PMC3097272

Abstract Article PDF–672K

Select item 28828844.

Human germinal center-associated lymphoma protein expression is associated with improved failure-free survival in Brazilian patients with classical Hodgkin lymphoma

DENIZE AZAMBUJA, IZIDORE S. LOSSOS, IRENE BIASOLI, JOSÉ CARLOS MORAIS, LUCIANA BRITTO, ADRIANA SCHELIGA, WOLMAR PULCHERI, YASODHA NATKUNAM, NELSON SPECTOR

Leuk Lymphoma. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Leuk Lymphoma. 2009 Nov; 50(11): 1830–1836. doi: 10.3109/10428190903242628

PMCID:: PMC2882884

Abstract Article PDF–389K

Select item 18950835.

Expression of the human germinal center–associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation

Yasodha Natkunam, Izidore S. Lossos, Behnaz Taidi, Shuchun Zhao, XiaoQing Lu, Feying Ding, Anne Sofie Hammer, Teresa Marafioti, Gerald E. Byrne, Jr, Shoshana Levy, Roger A Warnke, Ronald Levy

Blood. 2005 May 15; 105(10): 3979–3986. Prepublished online 2005 Jan 27. doi: 10.1182/blood-2004-08-3112

PMCID:: PMC1895083

Abstract Article

Select item 66930156.

Interplay between HGAL and Grb2 proteins regulates B-cell receptor signaling

Xiaoyu Jiang, Xiaoqing Lu, Yu Zhang, Leda Lacaria, Brett J. Schuchardt, David C. Mikles, Marco Magistri, Idoia García-Ramírez, Isidro Sanchez-Garcia, Amjad Farooq, Ramiro E. Verdun, Midhat H. Abdulreda, Vincent T. Moy, Izidore S. Lossos

Blood Adv. 2019 Aug 13; 3(15): 2286–2297. Published online 2019 Jul 30. doi: 10.1182/bloodadvances.2018016162

PMCID:: PMC6693015

Abstract Article PDF–2.3M

Select item 48471437.

The Efficacy of HGAL and LMO2 in the Separation of Lymphomas Derived From Small B Cells in Nodal and Extranodal Sites, Including the Bone Marrow

Sheren F. Younes, Andrew H. Beck, Robert S. Ohgami, Izidore S. Lossos, Ronald Levy, Roger A. Warnke, Yasodha Natkunam

Am J Clin Pathol. Author manuscript; available in PMC 2016 Apr 27.

Published in final edited form as: Am J Clin Pathol. 2011 May; 135(5): 697–708. doi: 10.1309/AJCP7Z2BIBUNQPLZ

PMCID:: PMC4847143

Abstract Article PDF–797K

Select item 29292848.

Immunoarchitectural Patterns in Follicular Lymphoma: Efficacy of HGAL and LMO2 in the Detection of the Interfollicular and Diffuse Components

Sheren Fouad-Younes, Andrew Beck, Izidore S Lossos, Ronald Levy, Roger A. Warnke, Yasodha Natkunam

Am J Surg Pathol. Author manuscript; available in PMC 2011 Sep 1.

Published in final edited form as: Am J Surg Pathol. 2010 Sep; 34(9): 1266–1276. doi: 10.1097/PAS.0b013e3181e9343d

PMCID:: PMC2929284

Abstract Article PDF–6.3M

Select item 18681639.

Two Newly Characterized Germinal Center B-Cell-Associated Genes, GCET1 and GCET2, Have Differential Expression in Normal and Neoplastic B Cells

Zenggang Pan, Yulei Shen, Cheng Du, Guimei Zhou, Andreas Rosenwald, Louis M. Staudt, Timothy C. Greiner, Timothy W. McKeithan, Wing C. Chan

Am J Pathol. 2003 Jul; 163(1): 135–144. doi: 10.1016/S0002-9440(10)63637-1

PMCID:: PMC1868163

Abstract Article PDF–829K

Select item 1047625110.

Value of GCET1, HGAL (GCET2), and LMO2 in the Determination of Germinal Center Phenotype in Diffuse Large B-cell Lymphoma

Neslihan Berker, Gülçin Yeğen, Yasemin Özlük, Öner Doğan

Turk J Haematol. 2023 Sep; 40(3): 162–173. Published online 2023 Aug 31. doi: 10.4274/tjh.galenos.2023.2023.0110

PMCID:: PMC10476251

Abstract Article PDF–2.4M

Select item 802026411.

Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice

Javier Raboso-Gallego, Ana Casado-García, Xiaoyu Jiang, Marta Isidro-Hernández, Andrew J. Gentles, Shuchun Zhao, Yaso Natkunam, Oscar Blanco, Verónica Domínguez, Belén Pintado, Diego Alonso-López, Javier De Las Rivas, Carolina Vicente-Dueñas, Izidore S. Lossos, Isidro Sanchez-Garcia

Blood. 2021 Apr 1; 137(13): 1741–1753. Prepublished online 2020 Oct 6. doi: 10.1182/blood.2020004996

PMCID:: PMC8020264

Abstract Article

Select item 354540612.

Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation

Isabel Romero-Camarero, Xiaoyu Jiang, Yasodha Natkunam, Xiaoqing Lu, Carolina Vicente-Dueñas, Ines Gonzalez-Herrero, Teresa Flores, Juan Luis Garcia, George McNamara, Christian Kunder, Shuchun Zhao, Victor Segura, Lorena Fontan, Jose A. Martínez-Climent, Francisco Javier García-Criado, Jason D. Theis, Ahmet Dogan, Elena Campos-Sánchez, Michael R. Green, Ash A. Alizadeh, Cesar Cobaleda, Isidro Sánchez-García, Izidore S. Lossos

Nat Commun. Author manuscript; available in PMC 2013 Jul 8.

Published in final edited form as: Nat Commun. 2013; 4: 1338. doi: 10.1038/ncomms2334

PMCID:: PMC3545406

Abstract Article PDF–2.5M

Select item 320190113.

Comparison of germinal center markers CD10, BCL6 and human germinal center-associated lymphoma (HGAL) in follicular lymphomas

Gaia Goteri, Guendalina Lucarini, Antonio Zizzi, Antonello Costagliola, Federica Giantomassi, Daniela Stramazzotti, Corrado Rubini, Pietro Leoni

Diagn Pathol. 2011; 6: 97. Published online 2011 Oct 11. doi: 10.1186/1746-1596-6-97

PMCID:: PMC3201901

Abstract Article PDF–5.9M

Select item 315884014.

PRDM1/Blimp1 Down-regulates Expression of Germinal Center Genes LMO2 and HGAL

Elena Cubedo, Michelle Maurin, Xiaoyu Jiang, Izidore S Lossos, Kenneth L. Wright

FEBS J. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: FEBS J. 2011 Sep; 278(17): 3065–3075. Published online 2011 Aug 2. doi: 10.1111/j.1742-4658.2011.08227.x

PMCID:: PMC3158840

Abstract Article PDF–1.1M

Select item 301253915.

HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway

Xiaoyu Jiang, Xiaoqing Lu, George McNamara, Xiaofei Liu, Elena Cubedo, Kristopher A. Sarosiek, Isidro Sánchez-García, David M. Helfman, Izidore S. Lossos

Blood. 2010 Dec 9; 116(24): 5217–5227. Prepublished online 2010 Sep 15. doi: 10.1182/blood-2010-04-281568

PMCID:: PMC3012539

Abstract Article

Select item 223478516.

HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration

Xiaoqing Lu, Jun Chen, Raquel Malumbres, Elena Cubedo Gil, David M. Helfman, Izidore S. Lossos

Blood. 2007 Dec 15; 110(13): 4268–4277. Prepublished online 2007 Sep 6. doi: 10.1182/blood-2007-04-087775

PMCID:: PMC2234785

Abstract Article

Select item 51531617.

Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions

Yutaka Suzuki, Riu Yamashita, Matsuyuki Shirota, Yuta Sakakibara, Joe Chiba, Junko Mizushima-Sugano, Kenta Nakai, Sumio Sugano

Genome Res. 2004 Sep; 14(9): 1711–1718. doi: 10.1101/gr.2435604

PMCID:: PMC515316

Abstract Article PDF–181K

Select item 464794118.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 889702219.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

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