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Select item 85052891.

Oestrogen-regulated protein SLC39A6: a biomarker of good prognosis in luminal breast cancer

Maryam Althobiti, Khloud A. El-sharawy, Chitra Joseph, Mohammed Aleskandarany, Michael S. Toss, Andrew R. Green, Emad A. Rakha

Breast Cancer Res Treat. 2021; 189(3): 621–630. Published online 2021 Aug 28. doi: 10.1007/s10549-021-06336-y

PMCID:: PMC8505289

Abstract Article PDF–1.1M

Select item 68391522.

Involvement of SLC39A6 in gastric adenocarcinoma and correlation of the SLC39A6 polymorphism rs1050631 with clinical outcomes after resection

Jian Gao, Wenjun Ren, Chunhong Xiao, Lie Wang, Qiaojia Huang, Zaizhong Zhang, Yuan Dang, Pengcheng Weng, Hui Wang, Xuehong Fang, Minxian Zhuang, Liying Lin, Shaoquan Chen

BMC Cancer. 2019; 19: 1069. Published online 2019 Nov 8. doi: 10.1186/s12885-019-6222-z

PMCID:: PMC6839152

Abstract Article PDF–3.5M

Select item 45952403.

SLC39A6: a potential target for diagnosis and therapy of esophageal carcinoma

Xiao-Bin Cui, Yao-yuan Shen, Ting-ting Jin, Su Li, Ting-ting Li, Shu-mao Zhang, Hao Peng, Chun-xia Liu, Shu-gang Li, Lan Yang, Na Li, Jian-ming Hu, Jin-Fang Jiang, Man Li, Wei-hua Liang, Yong Li, Yu-tao Wei, Zhen-zhu Sun, Chuan-yue Wu, Yun-Zhao Chen, Feng Li

J Transl Med. 2015; 13: 321. Published online 2015 Oct 6. doi: 10.1186/s12967-015-0681-z

PMCID:: PMC4595240

Abstract Article PDF–13M

Select item 34079874.

Zinc and Cancer: Implications for LIV-1 in Breast Cancer

Bruce J. Grattan, Hedley C. Freake

Nutrients. 2012 Jul; 4(7): 648–675. Published online 2012 Jul 4. doi: 10.3390/nu4070648

PMCID:: PMC3407987

Abstract Article PDF–240K

Select item 31353405.

Regulation of T cell receptor signaling by activation-induced zinc influx

Mingcan Yu, Won-Woo Lee, Deepak Tomar, Sergey Pryshchep, Marta Czesnikiewicz-Guzik, David L. Lamar, Guangjin Li, Karnail Singh, Lu Tian, Cornelia M. Weyand, Jörg J. Goronzy

J Exp Med. 2011 Apr 11; 208(4): 775–785. doi: 10.1084/jem.20100031

PMCID:: PMC3135340

Abstract Article PDF–1.6M

Select item 2667586.

Gene Expression Patterns in Ovarian Carcinomas

Marci E. Schaner, Douglas T. Ross, Giuseppe Ciaravino, Therese Sørlie, Olga Troyanskaya, Maximilian Diehn, Yan C. Wang, George E. Duran, Thomas L. Sikic, Sandra Caldeira, Hanne Skomedal, I-Ping Tu, Tina Hernandez-Boussard, Steven W. Johnson, Peter J. O'Dwyer, Michael J. Fero, Gunnar B. Kristensen, Anne-Lise Børresen-Dale, Trevor Hastie, Robert Tibshirani, Matt van de Rijn, Nelson N. Teng, Teri A. Longacre, David Botstein, Patrick O. Brown, Branimir I. Sikic

Mol Biol Cell. 2003 Nov; 14(11): 4376–4386. doi: 10.1091/mbc.E03-05-0279

PMCID:: PMC266758

Abstract Article PDF–1.3M

Select item 83586787.

Zap70 Regulates TCR-Mediated Zip6 Activation at the Immunological Synapse

Bonah Kim, Hee Young Kim, Won-Woo Lee

Front Immunol. 2021; 12: 687367. Published online 2021 Jul 29. doi: 10.3389/fimmu.2021.687367

PMCID:: PMC8358678

Abstract Article PDF–8.7M

Select item 45131318.

Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION

Ying Liu, Battsetseg Batchuluun, Louisa Ho, Dan Zhu, Kacey J. Prentice, Alpana Bhattacharjee, Ming Zhang, Farzaneh Pourasgari, Alexandre B. Hardy, Kathryn M. Taylor, Herbert Gaisano, Feihan F. Dai, Michael B. Wheeler

J Biol Chem. 2015 Jul 24; 290(30): 18757–18769. Published online 2015 May 12. doi: 10.1074/jbc.M115.640524

PMCID:: PMC4513131

Abstract Article PDF–1.2M

Select item 39386479.

High Glucose Level Promotes Migration Behavior of Breast Cancer Cells through Zinc and Its Transporters

Tomoka Takatani-Nakase, Chihiro Matsui, Sachie Maeda, Satomi Kawahara, Koichi Takahashi

PLoS One. 2014; 9(2): e90136. Published online 2014 Feb 28. doi: 10.1371/journal.pone.0090136

PMCID:: PMC3938647

Abstract Article PDF–611K

Select item 357788110.

Negative Correlation of LIV-1 and E-Cadherin Expression in Hepatocellular Carcinoma Cells

Rongxi Shen, Feng Xie, Hui Shen, Qu liu, Tao Zheng, Xingrui Kou, Dexian Wang, Jiamei Yang

PLoS One. 2013; 8(2): e56542. Published online 2013 Feb 20. doi: 10.1371/journal.pone.0056542

PMCID:: PMC3577881

Abstract Article PDF–259K

Select item 1054264711.

Suppression of SLC39A6‐CREB1 axis in liver cancer causes PCK1‐mediated mitochondrial dysfunction

Ze Yu, Cheng Chen, Hongpeng Gu, Jinliang Dong, Yingjie Zhang, Jie Wang, Haijie Ma, Guoqiang Zhang

Cell Prolif. 2023 Oct; 56(10): e13527. Published online 2023 Jul 12. doi: 10.1111/cpr.13527

PMCID:: PMC10542647

Article PDF–1.5M

Select item 790473712.

The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis

Thirayost Nimmanon, Silvia Ziliotto, Olivia Ogle, Anna Burt, Julia M. W. Gee, Glen K. Andrews, Pete Kille, Christer Hogstrand, Wolfgang Maret, Kathryn M. Taylor

Cell Mol Life Sci. 2021 Feb; 78(4): 1781–1798. Published online 2020 Aug 14. doi: 10.1007/s00018-020-03616-6

PMCID:: PMC7904737

Abstract Article PDF–4.1M

Select item 482306313.

miR-192, a prognostic indicator, targets the SLC39A6/SNAIL pathway to reduce tumor metastasis in human hepatocellular carcinoma

Junwei Lian, Ying Jing, Qiongzhu Dong, Lin Huan, Di Chen, Chunyang Bao, Qifeng Wang, Fangyu Zhao, Jinjun Li, Ming Yao, Lunxiu Qin, Linhui Liang, Xianghuo He

Oncotarget. 2016 Jan 19; 7(3): 2672–2683. Published online 2015 Dec 14. doi: 10.18632/oncotarget.6603

PMCID:: PMC4823063

Abstract Article PDF–4.7M

Select item 378923114.

A mechanism for epithelial–mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)

Christer Hogstrand, Peter Kille, Margaret Leigh Ackland, Stephen Hiscox, Kathryn M. Taylor

Biochem J. 2013 Oct 15; 455(Pt 2): 229–237. Prepublished online 2013 Aug 7. Published online 2013 Sep 27. doi: 10.1042/BJ20130483

PMCID:: PMC3789231

Abstract Article PDF–1.0M

Select item 694528015.

The LIV-1-GRPEL1 axis adjusts cell fate during anti-mitotic agent-damaged mitosis

Pingbo Chen, Beibei Wang, Qingqing Mo, Peng Wu, Yong Fang, Yuan Tian, Xin Jin, Yue Gao, Yuan Wu, Yang Cao, Yang Zhang, Ling Xi, Shixuan Wang, Junbo Hu, Ding Ma, Jianfeng Zhou, Qinglei Gao, Gang Chen

EBioMedicine. 2019 Nov; 49: 26–39. Published online 2019 Oct 19. doi: 10.1016/j.ebiom.2019.09.054

PMCID:: PMC6945280

Abstract Article PDF–5.9M

Select item 321802216.

LIV-1 Promotes Prostate Cancer Epithelial-to-Mesenchymal Transition and Metastasis through HB-EGF Shedding and EGFR-Mediated ERK Signaling

Hui-Wen Lue, Xiaojian Yang, Ruoxiang Wang, Weiping Qian, Roy Z. H. Xu, Robert Lyles, Adeboye O. Osunkoya, Binhua P. Zhou, Robert L. Vessella, Majd Zayzafoon, Zhi-Ren Liu, Haiyen E. Zhau, Leland W. K. Chung

PLoS One. 2011; 6(11): e27720. Published online 2011 Nov 16. doi: 10.1371/journal.pone.0027720

PMCID:: PMC3218022

Abstract Article PDF–3.2M

Select item 122366017.

Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters.

Kathryn M Taylor, Helen E Morgan, Andrea Johnson, Lisa J Hadley, Robert I Nicholson

Biochem J. 2003 Oct 1; 375(Pt 1): 51–59. doi: 10.1042/BJ20030478

PMCID:: PMC1223660

Summary PDF–293K

Select item 268036118.

Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia

Deborah French, Wenjian Yang, Cheng Cheng, Susana C. Raimondi, Charles G. Mullighan, James R. Downing, William E. Evans, Ching-Hon Pui, Mary V. Relling

Blood. 2009 May 7; 113(19): 4512–4520. Prepublished online 2008 Dec 9. doi: 10.1182/blood-2008-07-172106